Sealy JE, Yaqub T, Peacock TP, Chang P, et al. Association of Increased Receptor-Binding Avidity of Influenza A(H9N2) Viruses with Escape from Antibody-Based Immunity and Enhanced Zoonotic Potential. Emerg Infect Dis. 2019 Jan;25(1):63-72. Abstract
submitted by kickingbird at Dec, 23, 2018 from Emerg Infect Dis. 2019 Jan;25(1):63-72 (via https://wwwnc.cdc.gov/eid/article/25/1/18-0616_article)
We characterized 55 influenza A(H9N2) viruses isolated in Pakistan during 2014-2016 and found that the hemagglutinin gene is of the G1 lineage and that internal genes have differentiated into a variety ... Chen H, Alvarez JJS, Ng SH, Nielsen R, Zhai W. Passage adaptation correlates with the reduced efficacy of the influenza vaccine. Clin Infect Dis. 2018 Dec 18.. Abstract
submitted by kickingbird at Dec, 23, 2018 from Clin Infect Dis. 2018 Dec 18. (via https://www.ncbi.nlm.nih.gov/pubmed/30561532)
Background: As a dominant seasonal influenza virus, H3N2 virus rapidly evolves in human and is a constant threat to public health. Despite sustained research efforts, the efficacy of H3N2 vaccine has decreased ... van Asten L, et al. Estimating severity of influenza epidemics from severe acute respiratory infections (SARI) in intensive care units. Crit Care. 2018 Dec 19;22(1):351. Abstract
submitted by kickingbird at Dec, 23, 2018 from Crit Care. 2018 Dec 19;22(1):351 (via https://www.ncbi.nlm.nih.gov/pubmed/30567568)
BACKGROUND: While influenza-like-illness (ILI) surveillance is well-organized at primary care level in Europe, few data are available on more severe cases. With retrospective data from intensive care units ... Zhang J, Su R, Jian X, An H, Jiang R, Mok CKP. The D253N Mutation in the Polymerase Basic 2 Gene in Avian Influenza (H9N2) Virus Contributes to the Pathogenesis of the Virus in Mammalian Hosts. Virol Sin. 2018 Dec 19.. Abstract
submitted by kickingbird at Dec, 23, 2018 from Virol Sin. 2018 Dec 19. (via https://www.ncbi.nlm.nih.gov/pubmed/30569291)
Mutations in the polymerase basic 2 (PB2) gene of avian influenza viruses are important signatures for their adaptation to mammalian hosts. Various adaptive mutations have been identified around the 627 ... Rojas-Quintero J, et al. Matrix metalloproteinase-9 deficiency protects mice from severe influenza A viral infection. JCI Insight. 2018 Dec 20;3(24).. Abstract
submitted by kickingbird at Dec, 23, 2018 from JCI Insight. 2018 Dec 20;3(24). (via https://www.ncbi.nlm.nih.gov/pubmed/30568032)
Matrix metalloproteinase-9 (MMP-9) cleaves various proteins to regulate inflammatory and injury responses. However, MMP-9's activities during influenza A viral (IAV) infections are incompletely understood. ... Obadan AO, et al. Flexibility in vitro of amino acid 226 in the receptor-binding site of an H9 subtype influenza A virus and its effect in vivo on virus replication, tropism, and transmission. J Virol. 2018 Dec 19.. Abstract
submitted by kickingbird at Dec, 23, 2018 from J Virol. 2018 Dec 19. (via https://www.ncbi.nlm.nih.gov/pubmed/30567980)
Influenza A viruses remain a significant public health threat causing more than 300,000 hospitalizations in the United states during 2015-2016 season alone. While only few IAVs of avian origin have been ... Yin R, Zhou X, Zheng J, Kwoh CK. Computational identification of physicochemical signatures for host tropism of influenza A virus. J Bioinform Comput Biol. 2018 Oct 30:1840023.. Abstract
submitted by kickingbird at Dec, 23, 2018 from J Bioinform Comput Biol. 2018 Oct 30:1840023. (via https://www.ncbi.nlm.nih.gov/pubmed/30567479)
Avian influenza viruses from migratory birds have managed to cross host species barriers and infected various hosts like human and swine. Epidemics and pandemics might occur when influenza viruses are ... Howard LM, et al. AS03-Adjuvanted H5N1 Avian Influenza Vaccine Modulates Early Innate Immune Signatures In Human Peripheral Blood Mononuclear Cells. J Infect Dis. 2018 Dec 19. Abstract
submitted by kickingbird at Dec, 21, 2018 from J Infect Dis. 2018 Dec 19 (via https://www.ncbi.nlm.nih.gov/pubmed/30566602)
Background: Adjuvant System 03 (AS03) markedly enhances responses to influenza A/H5N1 vaccines, but the mechanisms of this enhancement are incompletely understood.Methods: Using RNA-Seq on peripheral blood ... Zhou P, et al. Serological Evidence of H3N2 Canine Influenza Virus Infection among Horses with Dog Exposure. Transbound Emerg Dis. 2018 Dec 19. Abstract
submitted by kickingbird at Dec, 21, 2018 from Transbound Emerg Dis. 2018 Dec 19 (via https://www.ncbi.nlm.nih.gov/pubmed/30565867)
Currently, Canine influenza virus (CIV) H3N2 is continuously circulating in dog populations in China, Korea, and the United States (US). Both influenza SA-α-2,3-Gal and SA-α-2,6-Gal receptors have been ... Wu T, Perrings C. The live poultry trade and the spread of highly pathogenic avian influenza: Regional differences between Europe, West Africa, and Southeast Asia. PLoS One. 2018 Dec 19;13(12):e0208197.. Abstract
submitted by kickingbird at Dec, 21, 2018 from PLoS One. 2018 Dec 19;13(12):e0208197. (via https://www.ncbi.nlm.nih.gov/pubmed/30566454)
In the past two decades, avian influenzas have posed an increasing international threat to human and livestock health. In particular, highly pathogenic avian influenza H5N1 has spread across Asia, Africa, ... Bischoff WE, et al. How well do N95 respirators protect healthcare providers against aerosolized influenza virus?. Infect Control Hosp Epidemiol. 2018 Dec 18:1-3.. Abstract
submitted by kickingbird at Dec, 20, 2018 from Infect Control Hosp Epidemiol. 2018 Dec 18:1-3. (via https://www.ncbi.nlm.nih.gov/pubmed/30558691)
N95 respirator masks are recommended for protection against respiratory viruses. Despite passing fit-testing 10% of N95 respirator users encountered breakthroughs with exposure to influenza virus compared ... Amaro RE, et al. A Computational Assay that Explores the Hemagglutinin/Neuraminidase Functional Balance Reveals the Neuraminidase Secondary Site as a Novel Anti-Influenza Target. ACS Cent Sci. 2018 Nov 28;4(11):1570-1577. Abstract
submitted by kickingbird at Dec, 20, 2018 from ACS Cent Sci. 2018 Nov 28;4(11):1570-1577 (via https://www.ncbi.nlm.nih.gov/pubmed/30555910)
Studies of pathogen-host specificity, virulence, and transmissibility are critical for basic research as well as for assessing the pandemic potential of emerging infectious diseases. This is especially ... Han L, et al. The evolution and molecular characteristics of H9N2 avian influenza viruses in Jiangxi of China. J Med Virol. 2018 Dec 17. Abstract
submitted by kickingbird at Dec, 20, 2018 from J Med Virol. 2018 Dec 17 (via https://www.ncbi.nlm.nih.gov/pubmed/30560545)
To understand the evolution and molecular characteristics of Jiangxi H9N2 viruses, we isolated 17 viruses in 2011 and analyzed their characteristics. Phylogenetic analyses revealed that their hemagglutinin ... Ali M, et al. Avian Influenza A(H9N2) Virus in Poultry Worker, Pakistan, 2015. Emerg Infect Dis. 2019 Jan;25(1):136-139. Abstract
submitted by kickingbird at Dec, 20, 2018 from Emerg Infect Dis. 2019 Jan;25(1):136-139 (via https://www.ncbi.nlm.nih.gov/pubmed/30561309)
Avian influenza A(H9N2) virus isolated from a poultry worker in Pakistan in 2015 was closely related to viruses detected in poultry farms. Observed mutations in the hemagglutinin related to receptor-binding ... Nogales A, Martinez-Sobrido L, Topham DJ, et al. Modulation of Innate Immune Responses by the Influenza A NS1 and PA-X Proteins. Viruses. 2018 Dec 12;10(12).. Abstract
submitted by kickingbird at Dec, 18, 2018 from Viruses. 2018 Dec 12;10(12). (via https://www.ncbi.nlm.nih.gov/pubmed/30545063)
Influenza A viruses (IAV) can infect a broad range of animal hosts, including humans. In humans, IAV causes seasonal annual epidemics and occasional pandemics, representing a serious public health and ... Liu WJ, et al. Clinical, immunological and bacteriological characteristics of H7N9 patients nosocomially co-infected by Acinetobacter Baumannii: a case control study. BMC Infect Dis. 2018 Dec 14;18(1):664. Abstract
submitted by kickingbird at Dec, 18, 2018 from BMC Infect Dis. 2018 Dec 14;18(1):664 (via https://www.ncbi.nlm.nih.gov/pubmed/30551738)
BACKGROUND: Bacterial co-infection of patients suffering from influenza pneumonia is a key element that increases morbidity and mortality. The occurrence of Acinetobacter baumannii co-infection in patients ... York IA, Stevens J, Alymova IV. Influenza Virus N-linked Glycosylation and Innate Immunity. Biosci Rep. 2018 Dec 14. Abstract
submitted by kickingbird at Dec, 18, 2018 from Biosci Rep. 2018 Dec 14 (via https://www.ncbi.nlm.nih.gov/pubmed/30552137)
Influenza viruses cause seasonal epidemics and sporadic pandemics in humans. The virus's ability to change its antigenic nature through mutation and recombination, and the difficulty in developing highly ... Tangwangvivat R, et al. Evidence of pandemic H1N1 influenza exposure in dogs and cats, Thailand: A serological survey. Zoonoses Public Health. 2018 Dec 14. Abstract
submitted by kickingbird at Dec, 18, 2018 from Zoonoses Public Health. 2018 Dec 14 (via https://www.ncbi.nlm.nih.gov/pubmed/30552750)
Influenza A virus causes respiratory disease in both humans and animals. In this study, a survey of influenza A antibodies in domestic dogs and cats was conducted in 47 animal shelters in 19 provinces ... Britton AP, et al. Probable reverse zoonosis of influenza A(H1N1)pdm 09 in a striped skunk (Mephitis mephitis). Zoonoses Public Health. 2018 Dec 14. Abstract
submitted by kickingbird at Dec, 18, 2018 from Zoonoses Public Health. 2018 Dec 14 (via https://www.ncbi.nlm.nih.gov/pubmed/30552753)
Striped skunks (skunks) are susceptible to respiratory infection by influenza A viruses (IAV). As they are common synanthropes, maintenance of IAV in skunks could provide a source of infection for humans. ... Oshansky CM, et al. Safety and immunogenicity of influenza A(H5N1) vaccine stored up to twelve years in the National Pre-Pandemic Influenza Vaccine Stockpile (NPIVS). Vaccine. 2018 Dec 12. Abstract
submitted by kickingbird at Dec, 18, 2018 from Vaccine. 2018 Dec 12 (via https://www.ncbi.nlm.nih.gov/pubmed/30553570)
BACKGROUND: As part of the U.S. Department of Health and Human Services (HHS) Pandemic Influenza Plan preparedness and response strategy, the National Pre-Pandemic Influenza Vaccine Stockpile (NPIVS) program ... 8128 items, 20/Page, Page[208/407][|<<] [|<] [201] [202] [203] [204] [205] [206] [207] [208] [209] [210] [>|] [>>|] |
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