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2024-10-12 5:52:24
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María Ríos Carrasco, Andrea Gr?ne, Judith M. A. v. The mammary glands of cows abundantly display receptors for circulating avian H5 viruses. Virology, 10 Oct 2024.  Abstract  
submitted by kickingbird at 8 hours ago from Virology, 10 Oct 2024 (via https://journals.asm.org/doi/10.1128/jvi.01052-24)
Influenza A viruses (IAVs) from the H5N1 2.3.4.4b clade are circulating in dairy farms in the USA.; ruminants were presumed not to be hosts for IAVs. Previously, IAV-positive mammalian species were hunters ...

Jarek Juraszek, etc.,al. Engineering a cleaved, prefusion-stabilized influenza B virus hemagglutinin by identification and locking of all six pH-switches. PNAS Nexus.  Abstract  
submitted by kickingbird at 8 hours ago from PNAS Nexus (via https://academic.oup.com/pnasnexus/advance-article/doi/10.10)
Vaccine components based on viral fusion proteins require high stability of the native prefusion conformation for optimal potency and manufacturability. In the case of influenza B virus hemagglutinin (HA), ...

Owuor DC, Ngoi JM, Nyasimi FM, Murunga N, Nyiro JU. Local patterns of spread of influenza A H3N2 virus in coastal Kenya over a 1-year period revealed through virus sequence data. Sci Rep. 2024 Oct 8;14(1):23426.  Abstract  
submitted by kickingbird at 8 hours ago from Sci Rep. 2024 Oct 8;14(1):23426 (via https://www.nature.com/articles/s41598-024-74218-6)
The patterns of spread of influenza A viruses in local populations in tropical and sub-tropical regions are unclear due to sparsity of representative spatiotemporal sequence data. We sequenced and analyzed ...

Zhang K, Cagatay T, Xie D, Angelos AE, Cornelius S. Cellular NS1-BP Protein Interacts with the mRNA Export Receptor NXF1 to Mediate Nuclear Export of Influenza Virus M mRNAs. J Biol Chem. 2024 Oct 7:107871.  Abstract  
submitted by kickingbird at 8 hours ago from J Biol Chem. 2024 Oct 7:107871 (via https://www.jbc.org/article/S0021-9258(24)02373-1/fulltext)
Influenza A viruses have eight genomic RNAs that are transcribed in the host cell nucleus. Two of the viral mRNAs undergo alternative splicing. The M1 mRNA encodes the matrix protein 1 (M1) and is also ...

Schaub A, Luo B, David SC, Glas I, Klein LK, Costa. Salt Supersaturation as an Accelerator of Influenza A Virus Inactivation in 1 μL Droplets. Environ Sci Technol. 2024 Oct 11.  Abstract  
submitted by kickingbird at 9 hours ago from Environ Sci Technol. 2024 Oct 11 (via https://pubs.acs.org/doi/10.1021/acs.est.4c04734)
Influenza A virus (IAV) spreads through exhaled aerosol particles and larger droplets. Estimating the stability of IAV is challenging and depends on factors such as the respiratory matrix and drying kinetics. ...

Musa E, Nia ZM, Bragazzi NL, Leung D, Lee N, Kong. Avian Influenza: Lessons from Past Outbreaks and an Inventory of Data Sources, Mathematical and AI Models, and Early Warning Systems for Forecasting and Hotspot Detection to Tackle Ongoing Outbreaks. Healthcare. 2024; 12(19):1959.  Abstract  
submitted by kickingbird at 9 hours ago from Healthcare. 2024; 12(19):1959 (via https://www.mdpi.com/2227-9032/12/19/1959)
Background/Objectives: The ongoing avian influenza (H5N1) outbreak, one of the most widespread and persistent in recent history, has significantly impacted public health and the poultry and dairy cattle ...

Andrew J Lee, etc.,al. Wastewater monitoring of human and avian influenza A viruses in Northern Ireland: a genomic surveillance study. The Lancet Microbe.  Abstract  
submitted by kickingbird at 9 hours ago from The Lancet Microbe (via https://www.sciencedirect.com/science/article/pii/S266652472)
BackgroundInfluenza A viruses (IAVs) are significant pathogens of humans and other animals. Although endemic in humans and birds, novel IAV strains can emerge, jump species, and cause epidemics, like the ...

Reina Yamaji, etc.,al. Pandemic risk characterisation of zoonotic influenza A viruses using the Tool for Influenza Pandemic Risk Assessment (TIPRA). The Lancet Microbe.  Abstract  
submitted by kickingbird at 9 hours ago from The Lancet Microbe (via https://www.sciencedirect.com/science/article/pii/S266652472)
A systematic risk assessment approach is essential for evaluating the relative risk of influenza A viruses (IAVs) with pandemic potential. To achieve this, the Tool for Influenza Pandemic Risk Assessment ...

Li Y, Sun Z, Liu X, Wei S, Zhang Y, Fuxiang Y, Qia. Highly Pathogenic Avian Influenza A(H5N1) Virus infection in dairy cattle:threat of bird flu has expanded to open-air farmed livestock. J Infect. 2024 Oct 7:106311.  Abstract  
submitted by kickingbird at 21 hours ago from J Infect. 2024 Oct 7:106311 (via https://www.journalofinfection.com/article/S0163-4453(24)002)
We read with interest the recent letter by Cai and colleagues who commented on recent cross-species activity of H5N1 Influenza virus and urged continuing surveillance of avian influenza. In March, the ...

Kessler S, Stegen P, Zhan S, Schwemmle M, Reuther. Jamaican fruit bats mount a stable and highly neutralizing antibody response after bat influenza virus infection. Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e241.  Abstract  
submitted by kickingbird at 21 hours ago from Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e241 (via https://pnas.org/doi/10.1073/pnas.2413619121)
Antibodies are an essential component of the antiviral response in many species, but to date, there is no compelling evidence that bats are capable of eliciting a robust humoral immunity, including neutralizing ...

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