El Taweel, A., Gomaa, M., Moatasim, Y. et al. Partial protection of commercial H5 avian influenza vaccines to clade 2.3.4·4b H5N1 and H5N8 avian influenza infections in chickens. Poult. Sci. Manag. 3, 22 (2026). Abstract
submitted by kickingbird at 1 days ago from Poult. Sci. Manag. 3, 22 (2026) (via https://link.springer.com/article/10.1186/s44364-026-00041-6)
BackgroundAvian influenza viruses (AIVs) continue to cause substantial economic losses to the poultry industry and pose a significant burden on global public health systems. The increasing diversity and ... Maria DA, Martins IM, Porto GPM, Villas-Boas IM, L. Safety, humoral and cellular immune responses to a pre-pandemic adjuvanted influenza A (H5N8) vaccine. Vaccine. 2026 Sep 4;92:129049. Abstract
submitted by kickingbird at 4 days ago from Vaccine. 2026 Sep 4;92:129049 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Highly pathogenic avian influenza (HPAI) A(H5) viruses can be transmitted from infected birds to various mammalian species, including humans. Avian influenza viruses (AIVs), members of the Orthomyxoviridae ... Kohei Oishi, etc.,al. An endonuclease inhibitor unlocks the PA-X shutoff mechanism in influenza A virus. Cell Reports. Abstract
submitted by kickingbird at 6 days ago from Cell Reports (via https://www.sciencedirect.com/science/article/pii/S221112472)
Influenza A virus protein PA-X mediates host shutoff, yet its molecular mechanism and the role of its C-terminal region remain unclear. When ectopically expressed via plasmids, PA-X cleaves its own mRNAs, ... Guo K, Chen X, Wang C, Liu Y, Liu C, Wu Y, Fan X,. A Novel Cell-Based High-Throughput Screening Model for Inhibitors Targeting Influenza Virus Hemagglutinin-α-2,6-Sialic Acid Interaction. Biomolecules. 2026; 16(9):1253. Abstract
submitted by kickingbird at 9 days ago from Biomolecules. 2026; 16(9):1253 (via https://www.mdpi.com/2218-273X/16/9/1253)
Rising drug resistance undermines current anti-influenza virus therapies. Although targeting the hemagglutinin (HA)–sialic acid receptor interaction is a promising strategy, progress is impeded by the ... Nguyen VH, Settembre E, Youhanna J, Beck E, Van de. Estimating the Relative Vaccine Efficacy of mRNA-1010 to High-Dose Influenza Vaccine in Adults ≥65 Years Using a Correlate of Protection Framework. Vaccines. 2026; 14(9):750. Abstract
submitted by kickingbird at 9 days ago from Vaccines. 2026; 14(9):750 (via https://www.mdpi.com/2076-393X/14/9/750)
Background/objective: Older adults experience a disproportionate burden of severe influenza. In the P303 trial (NCT058279789), mRNA-1010 showed greater immunogenicity versus high-dose inactivated influenza ... Jiaxin Bai, etc.,al. A Nanoemulsion-Adjuvanted Trivalent Neuraminidase Vaccine Confers Cross-Protection Against Divergent Influenza Viruses. Front. Cell. Infect. Microbiol.. Abstract
submitted by kickingbird at 10 days ago from Front. Cell. Infect. Microbiol. (via https://www.frontiersin.org/journals/cellular-and-infection-)
Developing universal influenza vaccines (UIVs) capable of eliciting broad protection remains a critical public health priority. Neuraminidase (NA), a relatively conserved surface antigen of influenza viruses, ... Ankita Singh, etc.,al. H5N1 influenza multi-epitope vaccine design through immunoinformatics approaches. Front. Appl. Math. Stat., 27 August 2026. Abstract
submitted by kickingbird at 12 days ago from Front. Appl. Math. Stat., 27 August 2026 (via https://www.frontiersin.org/journals/applied-mathematics-and)
The H5N1 avian influenza virus poses a significant threat to both animal and human health, with a high potential for triggering a global pandemic. This study outlines a step-by-step immunoinformatics-driven ... Eckhardt, E., Friedrich, J., Lange, W. et al. Comparison of the adjuvant effect of AS01, AS03 and alum on the immune response to GMP-grade H5N1 antigen in guinea pigs. Sci Rep 16, 26175 (2026). Abstract
submitted by kickingbird at Aug, 22, 2026 from Sci Rep 16, 26175 (2026) (via https://link.springer.com/article/10.1038/s41598-026-65812-x)
Adjuvants function as an enhancer and activator of the immune response and can be of pivotal importance for the efficacy of vaccines. AS01, which is a liposome formulation spiked with the saponin derivate ... Deffner, P., Jankowitsch, K., Eddicks, M. et al. Detecting swine influenza A virus during fattening and at slaughter: implications for monitoring strategies in fattening herds. Porc Health Manag 12, 46 (2026). Abstract
submitted by kickingbird at Aug, 22, 2026 from Porc Health Manag 12, 46 (2026) (via https://link.springer.com/article/10.1186/s40813-026-00529-x)
BackgroundSwine influenza A virus (swIAV) is a major contributor to respiratory disease in pigs and represents a One-Health concern. This study evaluated whether slaughterhouse sampling can complement ... Yu H, Zheng Y, Luo Y, Chang H, He D. A photonic crystal-based fluorescent sensing platform for visual detection of influenza A via hybridization chain reaction-mediated formation of polymer DNAzyme nanostructures. Anal Methods. 2026 Aug 18. Abstract
submitted by kickingbird at Aug, 19, 2026 from Anal Methods. 2026 Aug 18 (via https://pubs.rsc.org/ay/article-abstract/doi/10.1039/d6ay011)
Herein, we develop a robust fluorescent sensing platform based on functional photonic crystals (PCs) to achieve naked-eye visual detection of influenza A (H1N1) virus at an LOD of 0.32 pg mL-1. Benefiting ... David Edge, etc.,al. [preprint]Revolutionising notifiable avian disease diagnostics: validation of direct swab testing for Avian Influenza and Newcastle disease using the CENOS platform. https://doi.org/10.64898/2026.08.11.744268. Abstract
submitted by kickingbird at Aug, 19, 2026 from https://doi.org/10.64898/2026.08.11.744268 (via https://www.biorxiv.org/content/10.64898/2026.08.11.744268v1)
Existing molecular diagnostic approaches for notifiable avian diseases (NADs) involve a suite of PCR assays that enable both generic detection, and where positive, subtyping of both avian influenza virus ... Aebischer A, Günther A, Piesche R, Wernike K, Murr. Development of a multi-species luciferase-based double-antigen ELISA for the detection of antibodies against influenza A virus H5 clade 2.3.4.4b. J Clin Microbiol. 2026 Aug 13:e0190725. Abstract
submitted by kickingbird at Aug, 14, 2026 from J Clin Microbiol. 2026 Aug 13:e0190725 (via J Clin Microbiol. 2026 Aug 13:e0190725)
The highly pathogenic avian influenza viruses of subtype H5N1 represent a major threat to animal and public health. The current panzootic with H5 clade 2.3.4.4b has caused numerous, widespread outbreaks ... Rachel C. Williams, etc.,al. Comparative evaluation of sequencing technologies for public health surveillance of influenza virus in wastewater and environmental samples. Water Research. Abstract
submitted by kickingbird at Aug, 9, 2026 from Water Research (via https://www.sciencedirect.com/science/article/abs/pii/S00431)
Influenza viruses, notably influenza A (IAV), remain a persistent public health challenge due to high mutation rates and the rapid emergence of new strains. Wastewater-based epidemiology (WBE) offers a ... Van Twuijver, E., Versage, E., Jacobs, R. L, Hohenboken, M. Heterologous prime-boost vaccination against H5 avian influenza: Safety and immunogenicity of a MF59-adjuvanted, cell-culture derived H5N6 vaccine. Human Vaccines & Immunotherapeutics, 22(1). Abstract
submitted by kickingbird at Aug, 6, 2026 from Human Vaccines & Immunotherapeutics, 22(1) (via https://www.tandfonline.com/doi/full/10.1080/21645515.2026.2)
With increasing H5 avian influenza cases reported globally and the potential for pandemic emergence, induction of cross-reactive antibody responses may represent an important attribute of an effective ... Liu Y, Bai M, Zhang T, Cui Y, Du X, Huang L, Zhang. Comparative Immunogenicity of Inactivated H7N9 Avian Influenza Vaccines with Different Internal Gene Backbones. Microorganisms. 2026; 14(8):1719. Abstract
submitted by kickingbird at Aug, 6, 2026 from Microorganisms. 2026; 14(8):1719 (via https://www.mdpi.com/2076-2607/14/8/1719)
H7N9 avian influenza virus (AIV) poses a persistent threat to poultry and public health. Despite widespread vaccination in China, rapid antigenic drift and reassortment necessitate frequent updates of ... Xu N, Wang L, Zhao C, Shen Y, Zhao Z, Nie J. Advances in clinical immunogenicity evaluation of influenza vaccines. Vaccine. 2026 Aug 3;89:128989. Abstract
submitted by kickingbird at Aug, 4, 2026 from Vaccine. 2026 Aug 3;89:128989 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Influenza vaccination is an effective intervention for preventing severe influenza, and assessing its immunogenicity is a critical step in determining vaccine protective efficacy. With the widespread use ... Ximing Zeng, etc.,al. Rapid and specific detection of influenza virus antigens via surface-enhanced Raman scattering-based immunoassay. Talanta. Abstract
submitted by kickingbird at Aug, 3, 2026 from Talanta (via https://www.sciencedirect.com/science/article/abs/pii/S00399)
Influenza is currently one of the most prevalent respiratory diseases in humans, with outbreaks typically occurring during the winter months. Its impact is particularly pronounced among vulnerable populations, ... Portela Catani, J.P., Smet, A., Ysenbaert, T. et a. Influenza neuraminidase as adjuvanted protein or mRNA vaccine protects mice against influenza A and B virus challenge. npj Vaccines (2026). Abstract
submitted by kickingbird at Aug, 2, 2026 from npj Vaccines (2026) (via https://link.springer.com/article/10.1038/s41541-026-01536-3)
Neuraminidase (NA) is an underutilized influenza vaccine antigen despite its recognized contribution to protective immunity. Here, we compared the immunogenicity and protective potential of multiple NA ... Kim BK, Park JH, Choi WS, Oh S, An SH, Lee GC, Cho. Capless self-amplifying mRNA vaccine induces dose-sparing protective immunity against HPAI clade 2.3.4.4 H5 virus in mice. Mol Ther. 2026 Jul 29:S1525-0016(26)00668-4. Abstract
submitted by kickingbird at Aug, 1, 2026 from Mol Ther. 2026 Jul 29:S1525-0016(26)00668-4 (via https://www.cell.com/molecular-therapy-family/molecular-ther)
Self-amplifying mRNA (samRNA) vaccines can induce potent immune responses at lower doses than conventional non-replicating mRNA vaccines; however, large RNA size and manufacturing considerations associated ... Raymond Ash, etc.,al. Contribution of Influenza H5 Head and Stalk Domains to the Development of Functional Non-Neutralizing Antibodies Following Mucosal rH5-NE Vaccination. The Journal of Immunology. Abstract
submitted by kickingbird at Jul, 29, 2026 from The Journal of Immunology (via https://academic.oup.com/jimmunol/article/215/Supplement_1/v)
IntroductionIn a prior Phase 1 trial we showed that an intranasal (IN) recombinant hemagglutinin (HA) H5 vaccine (rH5; A/Indo/05) nanoemulsion-adjuvanted (rH5 NE) and given on days 1 and 29 effectively ... 409 items, 20/Page, Page[1/21][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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