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2024-7-12 22:37:44

Zhou Y, Chen W, Wang G, Lei Z, Zhang M, Li Y. A label-free H1N1 influenza virus immunosensor based on an N-LIG/Au laser induced graphene microelectrode. Anal Methods. 2024 Jul 11.  Abstract  
submitted by kickingbird at 11 hours ago from Anal Methods. 2024 Jul 11 (via https://pubs.rsc.org/en/content/articlelanding/2024/ay/d4ay0)
A label-free immunosensor based on an N-doped laser direct graphene (N-LIG)/Au electrode was proposed for H1N1 influenza virus detection. By utilizing the instantaneous high temperature of laser irradiation, ...

J Nuzzo, etc.,al. The United States Needs A Better Testing Playbook For Future Public Health Emergencies. https://doi.org/10.1377/hlthaff.2024.00038.  Abstract  
submitted by kickingbird at Jun, 21, 2024 from https://doi.org/10.1377/hlthaff.2024.00038 (via https://www.healthaffairs.org/doi/10.1377/hlthaff.2024.00038)
The absence of a comprehensive national playbook for developing and deploying testing has hindered the United States’ ability to rapidly suppress recent biological emergencies (for example, the COVID-19 ...

Wang Q, Wu S, Shuai J, Li Y, Fu X, Zhang M, Yu X,. Dual Gene Detection of H5N1 Avian Influenza Virus Based on Dual RT-RPA. Molecules. 2024; 29(12):2801.  Abstract  
submitted by kickingbird at Jun, 16, 2024 from Molecules. 2024; 29(12):2801 (via https://www.mdpi.com/1420-3049/29/12/2801)
The H5N1 avian influenza virus seriously affects the health of poultry and humans. Once infected, the mortality rate is very high. Therefore, accurate and timely detection of the H5N1 avian influenza virus ...

Ge F-f, Shen L-p, Yang D-q, Yang X-c, Li X, Shen H. H3N2 canine influenza virus-like particle vaccine with great protection in beagle dogs. Microbiol Spectr. 2024 Jun 14:e0044524.  Abstract  
submitted by kickingbird at Jun, 15, 2024 from Microbiol Spectr. 2024 Jun 14:e0044524 (via https://journals.asm.org/doi/10.1128/spectrum.00445-24)
In 2016, a distinct branch of H3N2 canine influenza virus (CIV) emerged, which has mutations related to mammalian adaptation and has replaced previously prevalent strains. This branch poses a risk of zoonotic ...

Lianyu Lu, etc.,al. Dissolution-Enhanced Luminescence Enhanced Digital Microfluidics Immunoassay for Sensitive and Automated Detection of H5N1. ACS Appl. Mater. Interfaces 2023, 15, 5, 6526–6535.  Abstract  
submitted by kickingbird at Jun, 11, 2024 from ACS Appl. Mater. Interfaces 2023, 15, 5, 6526–6535 (via https://pubs.acs.org/doi/10.1021/acsami.2c20289)
Protein bioassay is a critical tool for the screening and detection of protein biomarkers in disease diagnostics and biological applications. However, the detection sensitivity and system automation of ...

Wang X, Li S, Qu H, Hao L, Shao T, Wang K, Xia Z,. SERS-based immunomagnetic bead for rapid detection of H5N1 influenza virus. Influenza Other Respir Viruses. 2023 Mar 9;17(3):e.  Abstract  
submitted by kickingbird at Jun, 11, 2024 from Influenza Other Respir Viruses. 2023 Mar 9;17(3):e (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13114)
The surface-enhanced Raman scattering (SERS) has recently drawn attention in the detection of respiratory viruses, but there have been few reports of the direct detection of viruses. In this study, a sandwich ...

Wang Y, Ruan Q, Lei ZC, Lin SC, Zhu Z, Zhou L, Yan. Highly Sensitive and Automated Surface Enhanced Raman Scattering-based Immunoassay for H5N1 Detection with Digital Microfluidics. Anal Chem. 2018 Apr 17;90(8):5224-5231.  Abstract  
submitted by kickingbird at Jun, 11, 2024 from Anal Chem. 2018 Apr 17;90(8):5224-5231 (via https://pubs.acs.org/doi/10.1021/acs.analchem.8b00002)
Digital microfluidics (DMF) is a powerful platform for a broad range of applications, especially immunoassays having multiple steps, due to the advantages of low reagent consumption and high automatization. ...

Choi J, Martin SJ, Tripp RA, Tompkins SM, Dluhy RA. Detection of neuraminidase stalk motifs associated with enhanced N1 subtype influenza A virulence via Raman spectroscopy. Analyst. 2015 Nov 21;140(22):7748-60.  Abstract  
submitted by kickingbird at Jun, 11, 2024 from Analyst. 2015 Nov 21;140(22):7748-60 (via https://pubs.rsc.org/en/content/articlelanding/2015/an/c5an0)
Oligonucleotides corresponding to neuraminidase (NA) stalk motifs that have been associated with enhanced influenza virulence have been identified using surface-enhanced Raman spectroscopy (SERS). 5'-Thiolated ...

Zhou X, Wang S, Ma Y, Jiang Y, Li Y, Shi J, Deng G. On-Site and Visual Detection of the H5 Subtype Avian Influenza Virus Based on RT-RPA and CRISPR/Cas12a. Viruses. 2024; 16(5):753.  Abstract  
submitted by kickingbird at May, 25, 2024 from Viruses. 2024; 16(5):753 (via https://www.mdpi.com/1999-4915/16/5/753)
Avian influenza viruses (AIVs) of the H5 subtype rank among the most serious pathogens, leading to significant economic losses in the global poultry industry and posing risks to human health. Therefore, ...

Furey C, Scher G, Ye N, Kercher L, DeBeauchamp J,. Development of a nucleoside-modified mRNA vaccine against clade H5 highly pathogenic avian influenza virus. Nat Commun. 2024 May 23;15(1):4350.  Abstract  
submitted by kickingbird at May, 24, 2024 from Nat Commun. 2024 May 23;15(1):4350 (via https://www.nature.com/articles/s41467-024-48555-z)
mRNA lipid nanoparticle (LNP) vaccines would be useful during an influenza virus pandemic since they can be produced rapidly and do not require the generation of egg-adapted vaccine seed stocks. Highly ...

Chen X, Huang X, Kanwal S, Wang J, Wen J, Zhang D. A Portable Fluorescent Lateral Flow Immunoassay Platform for Rapid Detection of FluA. Biosensors 2024, 14(6), 263.  Abstract  
submitted by kickingbird at May, 24, 2024 from Biosensors 2024, 14(6), 263 (via https://www.mdpi.com/2079-6374/14/6/263)
The spread of the FluA virus poses significant public health concerns worldwide. Fluorescent lateral flow immunoassay (LFIA) test strips have emerged as vital tools for the early detection and monitoring ...

Se-Hee An, Na-Yeong Kim, etc.,al. Development and evaluation of a multiplex real-time RT-PCR assay for simultaneous detection of H5, H7, and H9 subtype avian influenza viruses. Journal of Virological Methods.  Abstract  
submitted by kickingbird at Apr, 28, 2024 from Journal of Virological Methods (via https://www.sciencedirect.com/science/article/abs/pii/S01660)
H5, H7 and H9 are the major subtypes of avian influenza virus (AIV) that cause economic losses in the poultry industry and sporadic zoonotic infection. Early detection of AIV is essential for preventing ...

Sanchez, P.L.; Andre, G.; Antipov, A.; Petrovsky,. Advax-SM?-Adjuvanted COBRA (H1/H3) Hemagglutinin Influenza Vaccines. Vaccines 2024, 12, 455.  Abstract  
submitted by kickingbird at Apr, 27, 2024 from Vaccines 2024, 12, 455 (via https://www.mdpi.com/2076-393X/12/5/455)
Adjuvants enhance immune responses stimulated by vaccines. To date, many seasonal influenza vaccines are not formulated with an adjuvant. In the present study, the adjuvant Advax-SM? was combined with ...

Xiang Li, etc.,al. Quick detection of H5N1 avian influenza virus by surface enhanced Raman scattering(SERS) using aptamer capture. Chin J Vet Sci Oct, 2023 Vol.43 No.10.  Abstract  
submitted by kickingbird at Apr, 26, 2024 from Chin J Vet Sci Oct, 2023 Vol.43 No.10 (via http://www.flu.org.cn/scn/article_detail.asp?articleId=20372)
A rapid detection method for H5N1 avian influenza virus was established based on the combination of SERS(surface enhanced Raman scattering)and aptamer capture.Two aptamers with good specificity and sensitivity ...

Fu X, Wang Q, Ma B, Zhang B, Sun K, Yu X, Ye Z, Zh. Advances in Detection Techniques for the H5N1 Avian Influenza Virus. Int J Mol Sci. 2023 Dec 5;24(24):17157.  Abstract  
submitted by kickingbird at Mar, 31, 2024 from Int J Mol Sci. 2023 Dec 5;24(24):17157 (via https://www.mdpi.com/1422-0067/24/24/17157)
Avian influenza is caused by avian influenza virus infection; the H5N1 avian influenza virus is a highly pathogenic subtype, affecting poultry and human health. Since the discovery of the highly pathogenic ...

Wang Q, Luo J, Li B, Ye Q, Xu W, Gao F, Zhou L, Lu. Reduction in Interferon-Stimulated Genes Contributes to High-Yield Production of Influenza Virus in Suspension MDCK Cells. Vaccines (Basel). 2024 Mar 9;12(3):287.  Abstract  
submitted by kickingbird at Mar, 29, 2024 from Vaccines (Basel). 2024 Mar 9;12(3):287 (via https://www.mdpi.com/2076-393X/12/3/287)
Compared with the traditional vaccine produced in embryonated chicken eggs, cell-based manufacturing represented by the Madin-Darby canine kidney (MDCK) cell line has a larger production scale and reduces ...

Shi H, Ross TM. Inactivated recombinant influenza vaccine: the promising direction for the next generation of influenza vaccine. Expert Rev Vaccines. 2024 Mar 20.  Abstract  
submitted by kickingbird at Mar, 22, 2024 from Expert Rev Vaccines. 2024 Mar 20 (via https://www.tandfonline.com/doi/full/10.1080/14760584.2024.2)
Introduction: Vaccination is the most effective method to control the prevalence of seasonal influenza and the most widely used influenza vaccine is the inactivated influenza vaccine (IIV). Each season, ...

Yang RS, Traver M, Barefoot N, Stephens T, Alabanz. Mosaic quadrivalent influenza vaccine single nanoparticle characterization. Sci Rep. 2024 Feb 24;14(1):4534.  Abstract  
submitted by kickingbird at Feb, 26, 2024 from Sci Rep. 2024 Feb 24;14(1):4534 (via https://www.nature.com/articles/s41598-024-54876-2)
Recent work by our laboratory and others indicates that co-display of multiple antigens on protein-based nanoparticles may be key to induce cross-reactive antibodies that provide broad protection against ...

Li F, Liu B, Xiong Y, Zhang Z, Zhang Q, Qiu R, Pen. Enhanced Downstream Processing for a Cell-Based Avian Influenza (H5N1) Vaccine. Vaccines (Basel). 2024 Jan 29;12(2):138.  Abstract  
submitted by kickingbird at Feb, 25, 2024 from Vaccines (Basel). 2024 Jan 29;12(2):138 (via https://www.mdpi.com/2076-393X/12/2/138)
H5N1 highly pathogenic avian influenza virus (HPAIV) infections pose a significant threat to human health, with a mortality rate of around 50%. Limited global approval of H5N1 HPAIV vaccines, excluding ...

Yang Z, Yu S, Xu Y, Zhao Y, Li L, Sun J, Wang X, G. The Screening and Mechanism of Influenza-Virus Sensitive MDCK Cell Lines for Influenza Vaccine Production. Diseases. 2024 Jan 10;12(1):20.  Abstract  
submitted by kickingbird at Jan, 22, 2024 from Diseases. 2024 Jan 10;12(1):20 (via https://www.mdpi.com/2079-9721/12/1/20)
Influenza is a potentially fatal acute respiratory viral disease caused by the influenza virus. Influenza viruses vary in antigenicity and spread rapidly, resulting in seasonal epidemics. Vaccination is ...

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