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2024-12-9 18:29:36
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Chudan Liang, Zequn Wang, etc.,al. Rapidly quantification of intact infectious H1N1 virus using ICA-qPCR and PMA-qPCR. Biosafety and Health Available online 26 November.  Abstract  
submitted by kickingbird at 10 days ago from Biosafety and Health Available online 26 November (via https://www.sciencedirect.com/science/article/pii/S259005362)
The increase in emerging and reemerging infectious diseases has underscored the need for the prompt monitoring of intact infectious viruses and the quick assessment of their infectivity. However, molecular ...

Kirby MK, Shu B, Keller MW, Wilson MM, Rambo-Marti. Discriminating North American Swine Influenza Viruses with a Portable, One-Step, Triplex Real-Time RT-PCR Assay, and Portable Sequencing. Viruses. 2024; 16(10):1557.  Abstract  
submitted by kickingbird at Oct, 22, 2024 from Viruses. 2024; 16(10):1557 (via https://www.mdpi.com/1999-4915/16/10/1557)
Swine harbors a genetically diverse population of swine influenza A viruses (IAV-S), with demonstrated potential to transmit to the human population, causing outbreaks and pandemics. Here, we describe ...

Lamb C, Pitre E, Ajufo S, Rigby C, Bisht K, Oade M. Quantification of influenza virus mini viral RNAs using Cas13. RNA. 2024 Oct 17:rna.080174.124.  Abstract  
submitted by kickingbird at Oct, 18, 2024 from RNA. 2024 Oct 17:rna.080174.124 (via https://rnajournal.cshlp.org/content/early/2024/10/17/rna.08)
Influenza A virus (IAV) RNA synthesis produces full-length and deletion-containing RNA molecules, which include defective viral genomes (DVG) and mini viral RNAs (mvRNA). Sequencing approaches have shown ...

Vatzia E, Paudyal B, Dema B, Carr BV, Sedaghat-Ros. Aerosol immunization with influenza matrix, nucleoprotein, or both prevents lung disease in pig. NPJ Vaccines. 2024 Oct 13;9(1):188.  Abstract  
submitted by kickingbird at Oct, 14, 2024 from NPJ Vaccines. 2024 Oct 13;9(1):188 (via https://www.nature.com/articles/s41541-024-00989-8)
Current influenza vaccines are strain-specific and require frequent updates to combat new strains, making a broadly protective influenza vaccine (BPIV) highly desirable. A promising strategy is to induce ...

Qin Li, etc.,al. Thin-film freeze-drying of an influenza virus hemagglutinin mRNA vaccine in unilamellar lipid nanoparticles with blebs. Journal of Controlled Release.  Abstract  
submitted by kickingbird at Oct, 13, 2024 from Journal of Controlled Release (via https://www.sciencedirect.com/science/article/abs/pii/S01683)
Messenger RNA (mRNA) vaccines have revolutionized the fight against infectious diseases and are poised to transform other therapeutic areas. Lipid nanoparticles (LNP) represent the most successful delivery ...

Tian Y, Lu X, Xiao D, Zhou C.. Long-Lasting Chemiluminescence Based on Functionalized Multicolor Protein Capsules for Multiple Visualization Detection of Avian Influenza Virus Biomarkers. Anal Chem. 2024 Oct 11.  Abstract  
submitted by kickingbird at Oct, 12, 2024 from Anal Chem. 2024 Oct 11 (via https://pubs.acs.org/doi/10.1021/acs.analchem.4c04248)
Long-lasting chemiluminescence (CL) emissions are necessary for improving the detection accuracy and expanding the application scope. Here, we have synthesized three oil-in-water (O/W) multicolor protein ...

Zhang YN, Gomes KB, Lee YZ, Ward G, Xie B, Auclair. A Single-Component Multilayered Self-Assembling Protein Nanoparticle Vaccine Based on Extracellular Domains of Matrix Protein 2 against Both Influenza A and B. Vaccines (Basel). 2024 Aug 28;12(9):975.  Abstract  
submitted by kickingbird at Oct, 1, 2024 from Vaccines (Basel). 2024 Aug 28;12(9):975 (via https://www.mdpi.com/2076-393X/12/9/975)
The development of an effective and broadly protective influenza vaccine against circulating and emerging strains remains elusive. In this study, we evaluated a potentially universal influenza vaccine ...

Zhao X, Zheng X, Yang X, Guo Q, Zhang Y, Lou J. Establishment of a Lateral Flow Dipstick Detection Method for Influenza A Virus Based on CRISPR/Cas12a System. China CDC Wkly. 2024 Sep 13;6(37):946-952.  Abstract  
submitted by kickingbird at Oct, 1, 2024 from China CDC Wkly. 2024 Sep 13;6(37):946-952 (via https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2024)
Objective: This study aimed to develop a rapid, visual PCR-CRISPR/Cas12-LFD method for detecting influenza A by utilizing the conserved region of the matrix protein gene.Method: We crafted universal degradation ...

Webby, R.J. The practical longevity of stockpiled A(H5N1) influenza vaccine. Nat Med (2024).  Abstract  
submitted by kickingbird at Sep, 27, 2024 from Nat Med (2024) (via https://www.nature.com/articles/s41591-024-03256-4)
Stockpiled A(H5N1) influenza vaccines made using viruses from the mid-2000s stimulate antibodies that cross-react with current strains, despite being separated by 20 years of viral evolution — supporting ...

Ricker R, Perea Lopez N, Terrones M, Loew M, Ghedi. Rapid and label-free influenza A virus subtyping using surface-enhanced Raman spectroscopy with incident-wavelength analysis. Biomed Opt Express. 2024 Aug 7;15(9):5081-5097..  Abstract  
submitted by kickingbird at Sep, 20, 2024 from Biomed Opt Express. 2024 Aug 7;15(9):5081-5097. (via https://opg.optica.org/boe/fulltext.cfm?uri=boe-15-9-5081&id)
Early virus identification is a key component of both patient treatment and epidemiological monitoring. In the case of influenza A virus infections, where the detection of subtypes associated with bird ...

Yang D, Liao Y, Huang L, Shi J, Wang J, Qiao Z, Ma. Epidermal Growth Factor Receptor Emerges as a Viable Target for Reducing Tumorigenicity of MDCK Cells. Genes. 2024; 15(9):1208.  Abstract  
submitted by kickingbird at Sep, 16, 2024 from Genes. 2024; 15(9):1208 (via https://www.mdpi.com/2073-4425/15/9/1208)
The MDCK cell line is perceived as better than the embryos of hen eggs for the production of influenza vaccines, but the tumorigenicity of these cells is concerning. Epidermal growth factor receptor (EGFR) ...

Chaves M, Hashish A, Osemeke O, Sato Y, Suarez DL,. Evaluation of Commercial RNA Extraction Protocols for Avian Influenza Virus Using Nanopore Metagenomic Sequencing. Viruses. 2024; 16(9):1429.  Abstract  
submitted by kickingbird at Sep, 16, 2024 from Viruses. 2024; 16(9):1429 (via https://www.mdpi.com/1999-4915/16/9/1429)
Avian influenza virus (AIV) is a significant threat to the poultry industry, necessitating rapid and accurate diagnosis. The current AIV diagnostic process relies on virus identification via real-time ...

Li J, Cui H, Zhang Y, Wang X, Liu H, Mu Y, Wang H,. A Rapid Detection Method for H3 Avian Influenza Viruses Based on RT-RAA. Animals (Basel). 2024 Sep 6;14(17):2601.  Abstract  
submitted by kickingbird at Sep, 15, 2024 from Animals (Basel). 2024 Sep 6;14(17):2601 (via https://www.mdpi.com/2076-2615/14/17/2601)
The continued evolution of H3 subtype avian influenza virus (AIV)-which crosses the interspecific barrier to infect humans-and the potential risk of genetic recombination with other subtypes pose serious ...

Gao P, Wu F, Liu J, Li R, Jiang X, Pan W, Zhao F,. Development of a dual-component biosensor for rapid and sensitive detection of influenza H7 and H5 subtypes. Talanta. 2024 Aug 13;280:126704.  Abstract  
submitted by kickingbird at Aug, 18, 2024 from Talanta. 2024 Aug 13;280:126704 (via https://www.sciencedirect.com/science/article/abs/pii/S00399)
The outbreak of highly pathogenic influenza virus subtypes, such as H7 and H5, presents a significant global health challenge, necessitating the development of rapid and sensitive diagnostic methods. In ...

Shen X, Zhang A, Zhao R, Yin L, Yin D, Dai Y, Hou. Effects of adding antibiotics to an inactivated oil-adjuvant avian influenza vaccine on vaccine characteristics and chick health. Poult Sci. 2024 Jul 29;103(10):104135.  Abstract  
submitted by kickingbird at Aug, 8, 2024 from Poult Sci. 2024 Jul 29;103(10):104135 (via https://www.sciencedirect.com/science/article/pii/S003257912)
During poultry immunization, antibiotics are typically added to inactivated oil-adjuvant avian influenza (AI) vaccines. Here, we evaluated the effects of adding ceftiofur, a third-generation cephalosporin, ...

Kang Sik Nam, etc., al. Air sampling and simultaneous detection of airborne influenza virus via gold nanorod-based plasmonic PCR. Journal of Hazardous Materials.  Abstract  
submitted by kickingbird at Jul, 14, 2024 from Journal of Hazardous Materials (via https://www.sciencedirect.com/science/article/abs/pii/S03043)
Reliable and sensitive virus detection is essential to prevent airborne virus transmission. The polymerase chain reaction (PCR) is one of the most compelling and effective diagnostic techniques for detecting ...

Sha-Sha Chen, Yong-Lei Yang, Hong-Yun Wang, Tian-K. CRISPR/Cas13a-based genome editing for establishing the detection method of H9N2 subtype avian influenza virus. Poultry Science, 2024, 104068.  Abstract  
submitted by kickingbird at Jul, 14, 2024 from Poultry Science, 2024, 104068 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Avian influenza virus (AIV) subtype H9N2 has significantly threatened the poultry business in recent years by having become the predominant subtype in flocks of chickens, ducks, and pigeons. In addition, ...

Zeng Z, Li Q, Guo H, Liu Y, Liang L, Lai Y, Fang Y. Modified transport medium for improving influenza virus detection. Front. Cell. Infect. Microbiol. 14:1399782.  Abstract  
submitted by kickingbird at Jul, 14, 2024 from Front. Cell. Infect. Microbiol. 14:1399782 (via https://www.frontiersin.org/journals/cellular-and-infection-)
Background: Accurate detection of influenza virus in clinical samples requires correct execution of all aspects of the detection test. If the viral load in a sample is below the detection limit, a false ...

Zhou Y, Chen W, Wang G, Lei Z, Zhang M, Li Y. A label-free H1N1 influenza virus immunosensor based on an N-LIG/Au laser induced graphene microelectrode. Anal Methods. 2024 Jul 11.  Abstract  
submitted by kickingbird at Jul, 12, 2024 from Anal Methods. 2024 Jul 11 (via https://pubs.rsc.org/en/content/articlelanding/2024/ay/d4ay0)
A label-free immunosensor based on an N-doped laser direct graphene (N-LIG)/Au electrode was proposed for H1N1 influenza virus detection. By utilizing the instantaneous high temperature of laser irradiation, ...

J Nuzzo, etc.,al. The United States Needs A Better Testing Playbook For Future Public Health Emergencies. https://doi.org/10.1377/hlthaff.2024.00038.  Abstract  
submitted by kickingbird at Jun, 21, 2024 from https://doi.org/10.1377/hlthaff.2024.00038 (via https://www.healthaffairs.org/doi/10.1377/hlthaff.2024.00038)
The absence of a comprehensive national playbook for developing and deploying testing has hindered the United States’ ability to rapidly suppress recent biological emergencies (for example, the COVID-19 ...

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