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2023-10-2 23:41:00
Article

Sumner KM, Masalovich S, O´Halloran A, Holst. Severity of influenza-associated hospitalisations by influenza virus type and subtype in the USA, 2010-19: a repeated cross-sectional study. Lancet Microbe. 2023 Sep 25:S2666-5247(23)00187-8.  Abstract  
submitted by kickingbird at 1 days ago from Lancet Microbe. 2023 Sep 25:S2666-5247(23)00187-8 (via https://www.thelancet.com/journals/lanmic/article/PIIS2666-5)
Background: Influenza burden varies across seasons, partly due to differences in circulating influenza virus types or subtypes. Using data from the US population-based surveillance system, Influenza Hospitalization ...

Andreev K, Jones JC, Seiler P, Kandeil A, Turner J. Antiviral Susceptibility of Highly Pathogenic Avian Influenza A(H5N1) Viruses Circulating Globally in 2022-2023. J Infect Dis. 2023 Sep 28:jiad418.  Abstract  
submitted by kickingbird at 1 days ago from J Infect Dis. 2023 Sep 28:jiad418 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
The antiviral susceptibility of currently circulating (2022-2023) highly pathogenic avian influenza (HPAI) A(H5N1) viruses was assessed by genotypic and phenotypic approaches. The frequency of neuraminidase ...

Barkhasbaatar A, Gilbert M, Fine AE, Shiilegdamba. Ecological characterization of 175 low-pathogenicity avian influenza viruses isolated from wild birds in Mongolia, 2009-2013 and 2016-2018. Vet Med Sci. 2023 Sep 28.  Abstract  
submitted by kickingbird at 1 days ago from Vet Med Sci. 2023 Sep 28 (via https://onlinelibrary.wiley.com/doi/10.1002/vms3.1281)
Background: Since 2005, highly pathogenic avian influenza A H5N1 viruses have spread from Asia worldwide, infecting poultry, humans and wild birds. Subsequently, global interest in avian influenza (AI) ...

Lei Y, Sun Y, Wu W, Liu H, Wang X, Shu Y, Fang S. Influenza H7N9 virus disrupts the monolayer human brain microvascular endothelial cells barrier in vitro. Virol J. 2023 Sep 29;20(1):219.  Abstract  
submitted by kickingbird at 1 days ago from Virol J. 2023 Sep 29;20(1):219 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Influenza H7N9 virus causes human infections with about 40% case fatality rate. The severe cases usually present with pneumonia; however, some present with central nervous system complications. Pneumonia ...

Wang S, Zhang TH, Hu M, Tang K, Sheng L, Hong M, C. Deep mutational scanning of influenza A virus neuraminidase facilitates the identification of drug resistance mutations in vivo. mSystems. 2023 Sep 29:e0067023.  Abstract  
submitted by kickingbird at 1 days ago from mSystems. 2023 Sep 29:e0067023 (via https://journals.asm.org/doi/10.1128/msystems.00670-23)
Neuraminidase (NA) is a pivotal surface enzyme and a key therapeutic target in combating the influenza A virus. Its evolution can lead to potential zoonotic transmission, seasonal epidemics, and the emergence ...

Petrich A, Chiantia S. Influenza A Virus Infection Alters Lipid Packing and Surface Electrostatic Potential of the Host Plasma Membrane. Viruses. 2023 Aug 29;15(9):1830.  Abstract  
submitted by kickingbird at 4 days ago from Viruses. 2023 Aug 29;15(9):1830 (via https://www.mdpi.com/1999-4915/15/9/1830)
The pathogenesis of influenza A viruses (IAVs) is influenced by several factors, including IAV strain origin and reassortment, tissue tropism and host type. While such factors were mostly investigated ...

Kanekiyo M, Gillespie RA, Midgett M, O´Malle. Refined semi-lethal aerosol H5N1 influenza model in cynomolgus macaques for evaluation of medical countermeasures. iScience. 2023 Sep 6;26(10):107830.  Abstract  
submitted by kickingbird at 4 days ago from iScience. 2023 Sep 6;26(10):107830 (via https://www.cell.com/iscience/fulltext/S2589-0042(23)01907-7)
Highly pathogenic avian influenza A H5N1 viruses cause high mortality in humans and have pandemic potential. Effective vaccines and treatments against this threat are urgently needed. Here, we have refined ...

Seekings AH, Warren CJ, Thomas SS, Lean FZX, Selde. Different Outcomes of Chicken Infection with UK-Origin H5N1-2020 and H5N8-2020 High-Pathogenicity Avian Influenza Viruses (Clade 2.3.4.4b). Viruses. 2023 Sep 12;15(9):1909.  Abstract  
submitted by kickingbird at 4 days ago from Viruses. 2023 Sep 12;15(9):1909 (via https://www.mdpi.com/1999-4915/15/9/1909)
Clade 2.3.4.4 H5Nx highly pathogenic avian influenza viruses (HPAIVs) of the "goose/Guangdong" lineage have caused a series of European epizootics since 2014. During autumn/winter 2020-2021, several H5Nx ...

Takashita E, Fujisaki S, Morita H, Nagata S, Miura. A community cluster of influenza A(H3N2) virus infection with reduced susceptibility to baloxavir due to a PA E199G substitution in Japan, February to March 2023. Euro Surveill. 2023 Sep;28(39).  Abstract  
submitted by kickingbird at 4 days ago from Euro Surveill. 2023 Sep;28(39) (via https://pubmed.ncbi.nlm.nih.gov/37768560/)
A community cluster of influenza A(H3N2) caused by viruses with an E199G substitution in PA was detected in Nara, Japan, between February and March 2023. The three patients with these mutant viruses had ...

Pepin KM, Leach CB, Barrett NL, Ellis JW, VanDalen. Environmental transmission of influenza A virus in mallards. mBio. 2023 Sep 28:e0086223.  Abstract  
submitted by kickingbird at 4 days ago from mBio. 2023 Sep 28:e0086223 (via https://journals.asm.org/doi/10.1128/mbio.00862-23)
Influenza A viruses present a major challenge for animal and human health. They circulate widely in wild waterfowl and frequently spillover into poultry, emphasizing the need for risk-based surveillance ...

Soda K, Mekata H, Usui T, Ito H, Matsui Y, Yamada. Genetic and antigenic analyses of H5N8 and H5N1 subtypes high pathogenicity avian influenza viruses isolated from wild birds and poultry farms in Japan in the winter of 2021-2022. J Vet Med Sci. 2023 Sep 26.  Abstract  
submitted by kickingbird at 4 days ago from J Vet Med Sci. 2023 Sep 26 (via https://www.jstage.jst.go.jp/article/jvms/advpub/0/advpub_23)
In the winter of 2021-2022, multiple subtypes (H5N8 and H5N1) of high pathogenicity avian influenza viruses (HPAIVs) were confirmed to be circulating simultaneously in Japan. Here, we phylogenetically ...

Qian Zhang, etc.,al. Isolation, identification and phylogenetic analysis of a wild bird-derived H1N1 avian influenza virus in the northern Tianshan Mountain. DOI: 10.3760/cma.j.cn112309-20200213-00060.  Abstract  
submitted by kickingbird at 10 days ago from DOI: 10.3760/cma.j.cn112309-20200213-00060 (via https://rs.yiigle.com/cmaid/1257546)
ObjectiveTo analyze the complete genome sequence and phylogenetic structure of a wild bird-derived H1N1 avian influenza virus (AIV) in the northern Tianshan Mountain.MethodsIn November 2018, 320 samples ...

Nana Chang, etc.,al. Isolation, identification and phylogenetic analysis of six strains of H5N6 highly pathogenic avian influenza virus. DOI: 10.3760/cma.j.cn112309-20210124-00036.  Abstract  
submitted by kickingbird at 10 days ago from DOI: 10.3760/cma.j.cn112309-20210124-00036 (via https://rs.yiigle.com/cmaid/1317811)
ObjectiveTo analyze phylogenetic structure and molecular characteristics of H5N6 avian influenza virus (AIVs) isolated from live poultry market (LPM).MethodsOropharyngeal and cloacal swabs from poultry, ...

Yonghu Wan, etc.,al. Genetic characteristics analysis of hemagglutinin gene of H9N2 subtype avian influenza viruses in Guizhou province. DOI: 10.3760/cma.j.cn112309-20201103-00498.  Abstract  
submitted by kickingbird at 13 days ago from DOI: 10.3760/cma.j.cn112309-20201103-00498 (via https://rs.yiigle.com/cmaid/1317812)
ObjectiveTo understand the genetic variation and the prevalence of H9N2 subtype avian influenza virus in Guizhou province, and to provide the scientific evidence for the prevention and control of avian ...

Jiang Liu, etc.,al. Analysis of the genome characteristics of H7N9 avian influenza virus in external environment in Huainan city in 2016. DOI: 10.3760/cma.j.cn112866-20200421-00138.  Abstract  
submitted by kickingbird at 13 days ago from DOI: 10.3760/cma.j.cn112866-20200421-00138 (via https://rs.yiigle.com/cmaid/1333295)
ObjectiveTo analyze the genomic characteristics of H7N9 avian influenza virus in external environment in Huainan city in 2016.MethodsSamples such as poultry feces, cages, table or cutting board, depilator, ...

Min Zhang, etc.,al. Molecular epidemiological investigation of avian influenza virus in live poultry market in Foshan city from 2017 to 2018. DOI: 10.3760/cma.j.issn.1673-4092.2021.05.015.  Abstract  
submitted by kickingbird at 13 days ago from DOI: 10.3760/cma.j.issn.1673-4092.2021.05.015 (via https://rs.yiigle.com/cmaid/1341321)
ObjectiveTo investigate the detection rate, epidemiological status of mixed positive and gene mutations of avian influenza virus in live poultry markets in Foshan city from 2017 to 2018, so as to assess ...

Briggs K, Kapczynski DR. Comparative analysis of PB2 residue 627E/K/V in H5 subtypes of avian influenza viruses isolated from birds and mammals. Front Vet Sci. 2023 Sep 1;10:1250952.  Abstract  
submitted by kickingbird at 14 days ago from Front Vet Sci. 2023 Sep 1;10:1250952 (via https://www.frontiersin.org/articles/10.3389/fvets.2023.1250)
Avian influenza viruses (AIVs) are naturally found in wild birds, primarily in migratory waterfowl. Although species barriers exist, many AIVs have demonstrated the ability to jump from bird species to ...

Gao R, Pascua PNQ, Nguyen HT, Chesnokov A, Champio. New insights into the neuraminidase-mediated hemagglutination activity of influenza A(H3N2) viruses. Antiviral Res. 2023 Sep 15:105719.  Abstract  
submitted by kickingbird at 14 days ago from Antiviral Res. 2023 Sep 15:105719 (via https://www.sciencedirect.com/science/article/pii/S016635422)
Influenza virus neuraminidase (NA) can act as a receptor-binding protein, a role commonly attributed to hemagglutinin (HA). In influenza A(H3N2) viruses, three NA amino acid residues have previously been ...

Jung Kj?r L, Ward MP, Boklund AE, Larsen LE, Hjuls. Using surveillance data for early warning modelling of highly pathogenic avian influenza in Europe reveals a seasonal shift in transmission, 2016-2022. Sci Rep. 2023 Sep 16;13(1):15396.  Abstract  
submitted by kickingbird at 15 days ago from Sci Rep. 2023 Sep 16;13(1):15396 (via https://www.nature.com/articles/s41598-023-42660-7)
Avian influenza in wild birds and poultry flocks constitutes a problem for animal welfare, food security and public health. In recent years there have been increasing numbers of outbreaks in Europe, with ...

Hewawaduge C, Kwon J, Sivasankar C, Park JY, Senev. Salmonella delivers H9N2 influenza virus antigens via a prokaryotic and eukaryotic dual-expression vector and elicits bivalent protection against avian influenza and fowl typhoid. Dev Comp Immunol. 2023 Sep 13:105058.  Abstract  
submitted by kickingbird at 16 days ago from Dev Comp Immunol. 2023 Sep 13:105058 (via https://www.sciencedirect.com/science/article/abs/pii/S01453)
The H9N2 avian influenza virus significantly affects the health of poultry and humans. We identified a prokaryotic and eukaryotic dual-expression vector system, pJHL270, that can provide simultaneous MHC ...

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