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2022-12-9 18:17:29
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Kandeil A, Kayed A, Moatasim Y, Aboulhoda BE, El T. Molecular identification and virological characteristics of highly pathogenic avian influenza A/H5N5 virus in wild birds in Egypt. Microb Pathog. 2022 Dec 2:105928.  Abstract  
submitted by kickingbird at 1 days ago from Microb Pathog. 2022 Dec 2:105928 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
Multiple incursions of different subtypes of highly pathogenic avian influenza (HPAI) A/H5NX viruses have caused widely considerable outbreaks in poultry and hundreds of human infections. Extensive reassortment ...

Ren W, Pei S, Jiang W, Zhao M, Jiang L, Liu H, Yi. A replication-deficient H9N2 influenza virus carrying H5 hemagglutinin conferred protection against H9N2 and H5N1 influenza viruses in mice. Front Microbiol. 2022 Nov 15;13:1042916.  Abstract  
submitted by kickingbird at 5 days ago from Front Microbiol. 2022 Nov 15;13:1042916 (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.1042)
H5N1 and H9N2 influenza viruses have been reported to cause human infections and are believed to have pandemic potential. The vaccine is an effective tool to prevent influenza virus infection. However, ...

Yang B, García-Carreras B, Lessler J, Read JM, Zhu. Long term intrinsic cycling in human life course antibody responses to influenza A(H3N2): an observational and modelling study. Elife. 2022 Dec 2;11:e81457.  Abstract  
submitted by kickingbird at 5 days ago from Elife. 2022 Dec 2;11:e81457 (via https://elifesciences.org/articles/81457)
Background: Over a life-course, human adaptive immunity to antigenically mutable pathogens exhibits competitive and facilitative interactions. We hypothesize that such interactions may lead to cyclic dynamics ...

Zhu H, Li X, Chen H, Qian P. Genetic characterization and pathogenicity of a Eurasian avian-like H1N1 swine influenza reassortant virus. Virol J. 2022 Dec 2;19(1):205.  Abstract  
submitted by kickingbird at 5 days ago from Virol J. 2022 Dec 2;19(1):205 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: Swine influenza viruses (SIV), considered the "mixing vessels" of influenza viruses, posed a significant threat to global health systems and are dangerous pathogens. Eurasian avian-like H1N1(EA-H1N1) ...

Ran W, Sch?n J, Ciminski K, Kraft J, Kessler S, Eu. Generation of an Attenuated Chimeric Bat Influenza A Virus Live-Vaccine Prototype. Microbiol Spectr. 2022 Nov 29:e0142422.  Abstract  
submitted by kickingbird at 9 days ago from Microbiol Spectr. 2022 Nov 29:e0142422 (via https://journals.asm.org/doi/10.1128/spectrum.01424-22)
Recurring epizootic influenza A virus (IAV) infections in domestic livestock such as swine and poultry are associated with a substantial economic burden and pose a constant threat to human health. Therefore, ...

Zhang C, Cui H, Zhang C, Zhao K, Kong Y, Chen L, D. Pathogenicity and Transmissibility of Clade 2.3.4.4h H5N6 Avian Influenza Viruses in Mammals. Animals (Basel). 2022 Nov 9;12(22):3079.  Abstract  
submitted by kickingbird at 11 days ago from Animals (Basel). 2022 Nov 9;12(22):3079 (via https://www.mdpi.com/2076-2615/12/22/3079)
Avian influenza viruses (AIVs) have the potential for cross-species transmission and pandemics. In recent years, clade 2.3.4.4 H5N6 AIVs are prevalent in domestic poultry, posing a threat to the domestic ...

Mashaal D, Mahmoud SH, Müller C, Abo Shama NM, Kam. Differential Impact of Specific Amino Acid Residues on the Characteristics of Avian Influenza Viruses in Mammalian Systems. Pathogens. 2022 Nov 19;11(11):1385.  Abstract  
submitted by kickingbird at 14 days ago from Pathogens. 2022 Nov 19;11(11):1385 (via https://www.mdpi.com/2076-0817/11/11/1385)
Avian influenza virus (AIV) H9N2 was declared to be endemic in birds of the Middle East, in particular in Egypt, with multiple cases of human infections. Despite concerns about the pandemic threat posed ...

Marchenko V, Mukhametdinova D, Amosova I, Lioznov. Influenza A(H1N1)pdm09 Virus Alters Expression of Endothelial Factors in Pulmonary Vascular Endothelium in Rats. Viruses. 2022 Nov 14;14(11):2518.  Abstract  
submitted by kickingbird at 14 days ago from Viruses. 2022 Nov 14;14(11):2518 (via https://www.mdpi.com/1999-4915/14/11/2518)
Influenza virus infection may cause endothelial activation and dysfunction. However, it is still not known to what extent the influenza virus can dysregulate the expression of various endothelial proteins. ...

Wang Y, Li X, Xu Q, Niu X, Zhang S, Qu X, Chu H, C. Characterization of Neutralizing Monoclonal Antibodies and Identification of a Novel Conserved C-Terminal Linear Epitope on the Hemagglutinin Protein of the H9N2 Avian Influenza Virus. Viruses. 2022 Nov 15;14(11):2530.  Abstract  
submitted by kickingbird at 14 days ago from Viruses. 2022 Nov 15;14(11):2530 (via https://www.mdpi.com/1999-4915/14/11/2530)
The H9N2 avian influenza virus (AIV) remains a serious threat to the global poultry industry and public health. The hemagglutinin (HA) protein is an essential protective antigen of AIVs and a major target ...

Liu T, Huang Y, Xie S, Xu L, Chen J, Qi W, Liao M,. A Characterization and an Evolutionary and a Pathogenicity Analysis of Reassortment H3N2 Avian Influenza Virus in South China in 2019-2020. Viruses. 2022 Nov 21;14(11):2574.  Abstract  
submitted by kickingbird at 14 days ago from Viruses. 2022 Nov 21;14(11):2574 (via https://www.mdpi.com/1999-4915/14/11/2574)
Seasonal H3N2 influenza virus has always been a potential threat to public health. The reassortment of the human and avian H3N2 influenza viruses has resulted in major influenza outbreaks, which have seriously ...

Niqueux é, Flodrops M, Allée C, Lebras MO, Pierre. Evaluation of three hemagglutinin-based vaccines for the experimental control of a panzootic clade 2.3.4.4b A(H5N8) high pathogenicity avian influenza virus in mule ducks. Vaccine. 2022 Nov 18:S0264-410X(22)01398-6.  Abstract  
submitted by kickingbird at Nov, 22, 2022 from Vaccine. 2022 Nov 18:S0264-410X(22)01398-6 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
In France during winter 2016-2017, 487 outbreaks of clade 2.3.4.4b H5N8 subtype high pathogenicity (HP) avian influenza A virus (AIV) infections were detected in poultry and captive birds. During this ...

Horwood PF, Horm SV, Yann S, Tok S, Chan M, Suttie. Aerosol exposure of live bird market workers to viable influenza A/H5N1 and A/H9N2 viruses, Cambodia. Zoonoses Public Health. 2022 Nov 21.  Abstract  
submitted by kickingbird at Nov, 22, 2022 from Zoonoses Public Health. 2022 Nov 21 (via https://onlinelibrary.wiley.com/doi/10.1111/zph.13009)
Live bird markets (LBMs) have been identified as key factors in the spread, persistence and evolution of avian influenza viruses (AIVs). In addition, these settings have been associated with human infections ...

Lai KK, Munro JB, Shi G, Majdoul S, Compton AA, Re. Restriction of Influenza A Virus by SERINC5. mBio. 2022 Nov 21:e0292322.  Abstract  
submitted by kickingbird at Nov, 22, 2022 from mBio. 2022 Nov 21:e0292322 (via https://journals.asm.org/doi/10.1128/mbio.02923-22)
Serine incorporator 5 (Ser5), a transmembrane protein, has recently been identified as a host antiviral factor against human immunodeficiency virus (HIV)-1 and gammaretroviruses like murine leukemia viruses ...

Liang Y, Hjulsager CK, Seekings AH, Warren CJ, Lea. Pathogenesis and infection dynamics of high pathogenicity avian influenza virus (HPAIV) H5N6 (clade 2.3.4.4b) in pheasants and onward transmission to chickens. Virology. 2022 Oct 29;577:138-148.  Abstract  
submitted by kickingbird at Nov, 17, 2022 from Virology. 2022 Oct 29;577:138-148 (via https://www.sciencedirect.com/science/article/pii/S004268222)
High pathogenicity avian influenza viruses clade 2.3.4.4 H5 have spread among wild birds worldwide during recent years causing annual die-offs among wild birds and outbreaks in poultry in multiple European ...

Zhou L, Yang H, Pan W, Xu J, Feng Y, Zhang W, Shao. Association between meteorological factors and the epidemics of influenza (sub)types in a subtropical basin of Southwest China. Epidemics. 2022 Nov 9;41:100650.  Abstract  
submitted by kickingbird at Nov, 16, 2022 from Epidemics. 2022 Nov 9;41:100650 (via https://www.sciencedirect.com/science/article/pii/S175543652)
Background: The effects of climatic conditions on the prevalence of individual influenza (sub)types are not well understood in the subtropics. This study aims to evaluate the associations between meteorological ...

Miller ML, Brown DM, Wysocki TA. Modeling an Immune Response to Influenza A Virus Infection in Alveolar Epithelial Cells. Biotechnol Bioeng. 2022 Nov 15.  Abstract  
submitted by kickingbird at Nov, 16, 2022 from Biotechnol Bioeng. 2022 Nov 15 (via https://onlinelibrary.wiley.com/doi/10.1002/bit.28284)
Influenza A viruses (IAV) have been the cause of several influenza pandemics in history and are a significant threat for the next global pandemic. Hospitalized influenza patients often have excess interferon ...

Human infections with H7N9 avian influenza A virus. H7N9 avian influenza virus infection in men is associated with testosterone depletion. Nat Commun. 2022 Nov 14;13(1):6936.  Abstract  
submitted by kickingbird at Nov, 16, 2022 from Nat Commun. 2022 Nov 14;13(1):6936 (via https://www.nature.com/articles/s41467-022-34500-5)
Human infections with H7N9 avian influenza A virus that emerged in East China in 2013 and caused high morbidity rates were more frequently detected in men than in women over the last five epidemic waves. ...

Zhang C, Cui H, Chen L, Yuan W, Dong S, Kong Y, Gu. Pathogenicity and Transmissibility of Goose-Origin H5N6 Avian Influenza Virus Clade 2.3.4.4h in Mammals. Viruses. 2022 Nov 5;14(11):2454.  Abstract  
submitted by kickingbird at Nov, 12, 2022 from Viruses. 2022 Nov 5;14(11):2454 (via https://www.mdpi.com/1999-4915/14/11/2454)
Throughout the last decade, H5N6 avian influenza viruses (AIVs) circulating in poultry and infecting humans have caused increasing global concerns that they might become a pandemic threat to global health. ...

Phyu WW, Saito R, Kyaw Y, Lin N, Win SMK, Win NC,. Evolutionary Dynamics of Whole-Genome Influenza A/H3N2 Viruses Isolated in Myanmar from 2015 to 2019. Viruses. 2022 Oct 31;14(11):2414.  Abstract  
submitted by kickingbird at Nov, 12, 2022 from Viruses. 2022 Oct 31;14(11):2414 (via https://www.mdpi.com/1999-4915/14/11/2414)
This study aimed to analyze the genetic and evolutionary characteristics of the influenza A/H3N2 viruses circulating in Myanmar from 2015 to 2019. Whole genomes from 79 virus isolates were amplified using ...

Petric PP, King J, Graf L, Pohlmann A, Beer M, Sch. Increased Polymerase Activity of Zoonotic H7N9 Allows Partial Escape from MxA. Viruses. 2022 Oct 24;14(11):2331.  Abstract  
submitted by kickingbird at Nov, 12, 2022 from Viruses. 2022 Oct 24;14(11):2331 (via https://www.mdpi.com/1999-4915/14/11/2331)
The interferon-induced myxovirus resistance protein A (MxA) is a potent restriction factor that prevents zoonotic infection from influenza A virus (IAV) subtype H7N9. Individuals expressing antivirally ...

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