An Y, Cai M, Zhao C, Zhang M, Wu X, Huang W, Zhou. Consensus H3N2 HA immunogens incorporating key antigenic mutations elicit broad-spectrum neutralising responses. Emerg Microbes Infect. 2026 Sep 7:2731497. Abstract
submitted by kickingbird at 1 days ago from Emerg Microbes Infect. 2026 Sep 7:2731497 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
Seasonal influenza A/H3N2 poses a significant public health burden due to its rapid antigenic evolution, necessitating frequent vaccine updates. This study systematically analysed the antigenic evolution ... Lu Y, Chen J, Xiao H, Li J, Wang H, Liang T, Wang. ATG13 Promotes K63-Linked Polyubiquitination of MAVS via ASB1 to Restrict Influenza A Virus Replication. Emerg Microbes Infect. 2026 Sep 7:2731501. Abstract
submitted by kickingbird at 1 days ago from Emerg Microbes Infect. 2026 Sep 7:2731501 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
Autophagy-associated protein 13 (ATG13) plays a pivotal role in regulating the assembly of the autophagy initiation complex. However, the function and mechanism of action of ATG13 during influenza virus ... Martin Beukema, etc.,al. [preprint]Antibody profiles across H5N1 and previously circulating viruses are highly dynamic and age- and imprint- independent. https://doi.org/10.64898/2026.08.26.26361396. Abstract
submitted by kickingbird at 2 days ago from https://doi.org/10.64898/2026.08.26.26361396 (via https://www.medrxiv.org/content/10.64898/2026.08.26.26361396)
The increasing incidence of H5N1 influenza virus transmission from animal species to humans has heightened concerns about an imminent H5N1 pandemic. Prior studies using recombinant hemagglutinin and neuraminidase ... Rondi FI, Neumann-Heise J, Harder T, Allendorf V,. Water-Wheat-Wait: Monitoring wild mallards (Anas platyrhynchos) for avian influenza and ESBL- E. coli using feed-baited water bins, Germany, 2022 to 2023. One Health. 2026 Aug 17;23:101548. Abstract
submitted by kickingbird at 2 days ago from One Health. 2026 Aug 17;23:101548 (via https://www.sciencedirect.com/science/article/pii/S235277142)
Background: The southern Baltic Sea coast is an important stopover region for wild waterbirds, particularly between late August and April. These birds can contribute to the maintenance and spread of viral ... Yoo DS, Oh Y. Three-Phase Decline in Reported Farm-Level Fowl Typhoid Occurrence in the Republic of Korea, 2000–2024: Temporal Alignment with the 2016–2017 H5N6 HPAI Epidemic. Animals. 2026; 16(17):2716. Abstract
submitted by kickingbird at 2 days ago from Animals. 2026; 16(17):2716 (via https://www.mdpi.com/2076-2615/16/17/2716)
This study characterized the long-term changes in reported farm-level fowl typhoid occurrence in the Republic of Korea from 2000 to 2024. Farm-level notification records (n = 1495) were obtained from the ... Hayden Farquhar. No receptor-binding domain adaptation detected in within-host H5N1 surveillance of 4,559 US dairy outbreak sequences. Virology. Abstract
submitted by kickingbird at 3 days ago from Virology (via https://www.sciencedirect.com/science/article/pii/S004268222)
BackgroundThe 2024–2026 US H5N1 clade 2.3.4.4b dairy cattle outbreak has been characterised primarily through consensus-level phylogenetics. Whether mammalian-adaptation variants are emerging at sub-consensus ... Ronja Piesche, etc.,al. [preprint]Experimental reproduction numbers disentangle vaccine effects on susceptibility and infectiousness during H5N1 transmission in geese. https://doi.org/10.64898/2026.09.02.748824. Abstract
submitted by kickingbird at 3 days ago from https://doi.org/10.64898/2026.09.02.748824 (via https://www.biorxiv.org/content/10.64898/2026.09.02.748824v1)
Vaccination against high pathogenicity avian influenza virus (HPAIV) is increasingly used to protect poultry, but vaccine performance is commonly inferred from clinical protection and virus shedding rather ... Moor N, Chen N, Behrens GMN, Zhang L, Moldenhauer. Host cell entry and neutralisation sensitivity of H3N2 influenza A virus subclade K. NPJ Vaccines. 2026 Sep 4;11(1):176. Abstract
submitted by kickingbird at 4 days ago from NPJ Vaccines. 2026 Sep 4;11(1):176 (via https://www.nature.com/articles/s41541-026-01573-y)
In 2025, a mutated H3N2 lineage, subclade K, emerged, showing high activity in many regions. Mutations in the hemagglutinin (HA) may affect cell entry and antibody-mediated neutralisation. Using pseudovirus ... Jin Y, Li X, Cui H, Zhang C, Li Y, Wang H, Wang Y,. Environmental Adaptability of Influenza A(H9N2) Virus in the Process of Genetic Evolution. J Med Virol. 2026 Sep;98(9):e71127. Abstract
submitted by kickingbird at 5 days ago from J Med Virol. 2026 Sep;98(9):e71127 (via https://onlinelibrary.wiley.com/doi/10.1002/jmv.71127)
Understanding the transmission routes of avian influenza viruses (AIVs) is critical for outbreak control. Beyond direct contact and aerosol transmission, indirect transmission via contaminated environmental ... Allison K. Miller, etc.,al. Evaluating sampling strategies for the detection of avian influenza viruses in the environment. Virology. Abstract
submitted by kickingbird at 5 days ago from Virology (via https://www.sciencedirect.com/science/article/pii/S004268222)
Highly pathogenic avian influenza (HPAI) viruses pose an increasing threat to wildlife, livestock and human health, underscoring the need for scalable and early-warning surveillance systems. Environmental ... Wataru Sekine, etc.,al. HA1-T138A and HA1-Q226L substitutions in H3N2 canine influenza virus contribute to binding to human-type α2,6-linked sialic acid receptors. Virology. Abstract
submitted by kickingbird at 5 days ago from Virology (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
The H3N2 canine influenza A virus (IAV), which originated from an H3N2 avian IAV, has caused outbreaks in North America and Asia. Although H3N2 canine IAV has not been reported to transmit to humans, understanding ... Fanny Oldensand, etc.,al. Single-cell transcriptomic landscape of avian influenza H9N2 virus infection in human and chicken cells. Virology. Abstract
submitted by kickingbird at 5 days ago from Virology (via https://www.sciencedirect.com/science/article/pii/S004268222)
Avian influenza viruses circulate naturally among migratory wild birds but can occasionally infect other species, including poultry and a broad range of mammals and humans. Although highly pathogenic avian ... Yee-Chen Liu, etc.,al. [preprint]Immunogen selection and prior immunity shape antibody breadth following immunisation with avian H5 hemagglutinin. https://doi.org/10.64898/2026.09.01.748495. Abstract
submitted by kickingbird at 6 days ago from https://doi.org/10.64898/2026.09.01.748495 (via https://www.biorxiv.org/content/10.64898/2026.09.01.748495v1)
Avian influenza A viruses pose a persistent zoonotic threat to humans owing to their expanding host range and high case fatality rates. In particular, viruses from the 2.3.4.4b clade of the H5 subtype ... Wenyu Liu, etc.,al. Optimized electroporation-mediated delivery enhances the immunogenicity of an H5/H7 trivalent avian influenza DNA vaccine. Journal of Integrative Agriculture. Abstract
submitted by kickingbird at 6 days ago from Journal of Integrative Agriculture (via https://www.sciencedirect.com/science/article/pii/S209531192)
Highly pathogenic avian influenza viruses (HPAIVs) of the H5 and H7 subtypes continue to cause devastating outbreaks in poultry worldwide, resulting in substantial economic losses and persistent zoonotic ... I. Garcia-Atutxa, F. Villanueva-Flores. Mechanistically interpretable reconstruction of human A(H5N8) humoral dynamics from sparse open serology with comparator modeling, practical identifiability analysis, and external validation. Vacunas. Abstract
submitted by kickingbird at 6 days ago from Vacunas (via https://www.sciencedirect.com/science/article/abs/pii/S15769)
IntroductionHuman A(H5N8) vaccine datasets are increasingly important for pandemic preparedness because contemporary A(H5) viruses continue to circulate across animal reservoirs and occasionally infect ... Gabriel Dupre, etc.,al. [preprint]Mechanism-based prediction of insertion-driven high pathogenicity avian influenza virus emergence. https://doi.org/10.64898/2026.08.27.747464. Abstract
submitted by kickingbird at 7 days ago from https://doi.org/10.64898/2026.08.27.747464 (via https://www.biorxiv.org/content/10.64898/2026.08.27.747464v1)
High pathogenicity avian influenza viruses (HPAIVs) emerge from H5 and H7 low-pathogenicity avian influenza virus progenitors through mutations that introduce a multibasic cleavage site in haemagglutinin. ... Liu D, Zhang Y, Zhang M, Guo R, Peng W, Cao R, Yan. A neuraminidase-targeting nanobody as a therapeutic candidate against influenza A and B viruses. J Virol 0:e00874-26. Abstract
submitted by kickingbird at 7 days ago from J Virol 0:e00874-26 (via https://journals.asm.org/doi/10.1128/jvi.00874-26)
Influenza viruses continue to pose a significant threat to human and animal health. However, the limited number of licensed antivirals is increasingly compromised by drug resistance driven by high mutation ... Lee S, Cho S, Kim H, Shin W, Lee S, Demirev AV, Ki. Genome-informed structural analysis of polymerase and glycoprotein adaptation in H5N1 clade 2.3.4.4b. J Vet Sci. 2026 Jul 14. Abstract
submitted by kickingbird at 8 days ago from J Vet Sci. 2026 Jul 14 (via https://vetsci.org/DOIx.php?id=10.4142/jvs.26088)
Importance: Understanding the molecular mechanisms driving H5N1 clade 2.3.4.4b is critical for pandemic preparedness.Objective: To characterize the molecular drivers of viral fitness and mammalian adaptability ... Jesse Bloom. Near-real time mapping of the human neutralizing antibody landscape to influenza to inform vaccine selection. Options for Control of Influenza Meeting August 30. Abstract
submitted by kickingbird at 10 days ago from Options for Control of Influenza Meeting August 30 (via https://slides.com/jbloom/options2026)
[presentations] options2026 Near-real time mapping of the human neutralizing antibody landscape to influenza to inform vaccine selection. Brogaard L, Laybourn HA, Kristensen C, Welner S, L. Site-specific microRNA responses in lungs of pigs depend on the host-adaptation of H1N1 influenza A virus. Virology. 2026 Aug 27;624:111053. Abstract
submitted by kickingbird at 10 days ago from Virology. 2026 Aug 27;624:111053 (via https://www.sciencedirect.com/science/article/pii/S004268222)
Cross-species transmission of influenza A virus (IAV) represents a major risk for emergence of new pandemics, however, the host molecular responses invoked by cross-species IAV infection remain incompletely ... 7118 items, 20/Page, Page[1/356][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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