Bamunuarachchi G, Yang X, Huang C, Liang Y, Guo Y,. MicroRNA-206 Inhibits Influenza A Virus Replication by Targeting Tankyrase 2. Cell Microbiol. 2020 Oct 25:e13281. Abstract
submitted by kickingbird at 18 hours ago from Cell Microbiol. 2020 Oct 25:e13281 (via https://onlinelibrary.wiley.com/doi/10.1111/cmi.13281)
Due to the frequent mutations, influenza A virus (IAV) becomes resistant to anti-viral drugs targeting influenza viral proteins. There are increasing interests in anti-viral agents that target host cellular ...
Sharma A, Batra J, Stuchlik O, Reed MS, Pohl J, Ch. Influenza A Virus Nucleoprotein Activates the JNK Stress-Signaling Pathway for Viral Replication by Sequestering Host Filamin A Protein. Front Microbiol. 2020 Sep 25;11:581867. Abstract
submitted by kickingbird at 18 hours ago from Front Microbiol. 2020 Sep 25;11:581867 (via https://www.frontiersin.org/articles/10.3389/fmicb.2020.5818)
Influenza A virus (IAV) poses a major threat to global public health and is known to employ various strategies to usurp the host machinery for survival. Due to its fast-evolving nature, IAVs tend to escape ...
Burke DF, Mantell RG, Pitt CE, Wales DJ. Energy Landscape for the Membrane Fusion Pathway in Influenza A Hemagglutinin From Discrete Path Samplin. Front Chem. 2020 Sep 25;8:575195. Abstract
submitted by kickingbird at 18 hours ago from Front Chem. 2020 Sep 25;8:575195 (via https://www.frontiersin.org/articles/10.3389/fchem.2020.5751)
The conformational change associated with membrane fusion for Influenza A Hemagglutinin is investigated with a model based upon pre- and post-fusion structures of the HA2 component. We employ computational ...
Poulson R, Carter D, Beville S, Niles L, Dey A, Mi. Influenza A Viruses in Ruddy Turnstones ( Arenaria interpres); Connecting Wintering and Migratory Sites with an Ecological Hotspot at Delaware Bay. Viruses. 2020 Oct 22;12(11):E1205. Abstract
submitted by kickingbird at 18 hours ago from Viruses. 2020 Oct 22;12(11):E1205 (via https://www.mdpi.com/1999-4915/12/11/1205)
Each May for over three decades, avian influenza A viruses (IAVs) have been isolated from shorebirds and gulls (order Charadriiformes) at Delaware Bay (DE Bay), USA, which is a critical stopover site for ...
Liu LQ, Li Z, Jiao M, Lu J, Zhou JF, Li XY, Liu J,. Development and Assessment of Two Highly Pathogenic Avian Influenza (HPAI) H5N6 Candidate Vaccine Viruses for Pandemic Preparedness. Biomed Environ Sci. 2020 Sep 20;33(9):670-679. Abstract
submitted by kickingbird at 18 hours ago from Biomed Environ Sci. 2020 Sep 20;33(9):670-679 (via http://www.besjournal.com/en/article/doi/10.3967/bes2020.088)
Objective: In China, 24 cases of human infection with highly pathogenic avian influenza (HPAI) H5N6 virus have been confirmed since the first confirmed case in 2014. Therefore, we developed and assessed ...
Quandelacy TM, Cummings DAT, Jiang CQ, Yang B, Kwo. Using serological measures to estimate influenza incidence in the presence of secular trends in exposure and immuno-modulation of antibody response. Influenza Other Respir Viruses. 2020 Oct 27. Abstract
submitted by kickingbird at 18 hours ago from Influenza Other Respir Viruses. 2020 Oct 27 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.12807)
Background: Influenza infection is often measured by a fourfold antibody titer increase over an influenza season (ie seroconversion). However, this approach may fail when influenza seasons are less distinct ...
Wang Y, Chen X, Yuan Y. Antibody Response of a H9 Subtype Avian Influenza Poultry Vaccine on Three Kinds of Wild Birds in Shanghai Zoo. Avian Dis. 2020 Oct 27. Abstract
submitted by kickingbird at 18 hours ago from Avian Dis. 2020 Oct 27 (via https://pubmed.ncbi.nlm.nih.gov/33108447/)
A semi-annual immunization with a commercial inactivated H9 subtype avian influenza virus (AIV) vaccine developed for poultry has been used to prevent and control the avian influenza (AI) infections among ...
Malosh RE, Petrie JG, Callear AP, Monto AS, Martin. Home collection of nasal swabs for detection of influenza in the Household Influenza Vaccine Evaluation Study. Influenza Other Respir Viruses. 2020 Oct 26. Abstract
submitted by kickingbird at 18 hours ago from Influenza Other Respir Viruses. 2020 Oct 26 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.12822)
Background: Community-based studies of influenza and other respiratory viruses (eg, SARS-CoV-2) require laboratory confirmation of infection. During the current COVID-19 pandemic, social distancing guidelines ...
Gao Q, Yang C, Ren C, Zhang S, Gao X, Jin M, Chen. Eukaryotic translation elongation factor 1 delta inhibits the nuclear import of nucleoprotein and PA-PB1 heterodimer of influenza A virus. J Virol. 2020 Oct 21:JVI.01391-20. Abstract
submitted by kickingbird at 3 days ago from J Virol. 2020 Oct 21:JVI.01391-20 (via https://jvi.asm.org/content/early/2020/10/16/JVI.01391-20)
The viral ribonucleoprotein (vRNP) of the influenza A virus (IAV) is responsible for the viral RNA transcription and replication in the nucleus and its functions rely on host factors. Previous study has ...
Deng L, Xu H, Liu P, Wu S, Shi Y, Lv Y, Chen X. Prolonged exposure to high humidity and high temperature environment can aggravate influenza virus infection through intestinal flora and Nod/RIP2/NF-κB signaling pathway. Vet Microbiol. 2020 Oct 16;251:108896. Abstract
submitted by kickingbird at 3 days ago from Vet Microbiol. 2020 Oct 16;251:108896 (via https://www.sciencedirect.com/science/article/pii/S037811352)
Seasonal influenza is an acute viral infection caused by influenza virus, which is often prevalent in the summer and winter. The influenza virus can infect pigs and poultry. Some literature reports that ...
Kajiwara N, Nomura N, Ukaji M, Yamamoto N, Kohara. Cell-penetrating peptide-mediated cell entry of H5N1 highly pathogenic avian influenza virus. Sci Rep. 2020 Oct 22;10(1):18008. Abstract
submitted by kickingbird at 3 days ago from Sci Rep. 2020 Oct 22;10(1):18008 (via https://www.nature.com/articles/s41598-020-74604-w)
H5N1 highly pathogenic avian influenza virus (HPAIV) poses a huge threat to public health and the global economy. These viruses cause systemic infection in poultry and accidental human infection leads ...
Karwelat D, Schmeck B, Ringel M, Benedikter BJ, Hü. Influenza virus-mediated suppression of bronchial Chitinase-3-like 1 secretion promotes secondary pneumococcal infection. FASEB J. 2020 Oct 23. Abstract
submitted by kickingbird at 3 days ago from FASEB J. 2020 Oct 23 (via https://faseb.onlinelibrary.wiley.com/doi/10.1096/fj.2019029)
Infections of the lung are among the leading causes of death worldwide. Despite the preactivation of innate defense programs during viral infection, secondary bacterial infection substantially elevates ...
Ciminski K, Chase GP, Beer M, Schwemmle M. Influenza A Viruses: Understanding Human Host Determinants. Trends Mol Med. 2020 Oct 20:S1471-4914(20)30261-6. Abstract
submitted by kickingbird at 3 days ago from Trends Mol Med. 2020 Oct 20:S1471-4914(20)30261-6 (via https://www.cell.com/trends/molecular-medicine/fulltext/S147)
Previous influenza A virus (IAV) pandemics have invariably been caused by the introduction of an emergent IAV strain from an animal host into a human population with no or only little pre-existing immunity ...
Gorsich EE, Webb CT, Merton AA, Hoeting JA, Miller. Continental-scale dynamics of avian influenza in U.S. waterfowl are driven by demography, migration, and temperature. Ecol Appl. 2020 Oct 24:e2245. Abstract
submitted by kickingbird at 3 days ago from Ecol Appl. 2020 Oct 24:e2245 (via https://esajournals.onlinelibrary.wiley.com/doi/10.1002/eap.)
Emerging diseases of wildlife origin are increasingly spilling over into humans and domestic animals. Surveillance and risk assessments for transmission between these populations are informed by a mechanistic ...
Drori Y, Jacob-Hirsch J, Pando R, Glatman-Freedman. Influenza A Virus Inhibits RSV Infection via a Two-Wave Expression of IFIT Proteins. Viruses. 2020 Oct 16;12(10):E1171. Abstract
submitted by kickingbird at 7 days ago from Viruses. 2020 Oct 16;12(10):E1171 (via https://www.mdpi.com/1999-4915/12/10/1171)
Influenza viruses and respiratory syncytial virus (RSV) are respiratory viruses that primarily circulate worldwide during the autumn and winter seasons. Seasonal surveillance has shown that RSV infection ...
Li S, Qiao Y, Xu Y, Li P, Nie J, Zhao Q, Chai W, S. Identification of Linear Peptide Immunogens with Verified Broad-spectrum Immunogenicity from the Conserved Regions within the Hemagglutinin Stem Domain of H1N1 Influenza Virus. Immunol Invest. 2020 Oct 20:1-14. Abstract
submitted by kickingbird at 8 days ago from Immunol Invest. 2020 Oct 20:1-14 (via https://www.tandfonline.com/doi/abs/10.1080/08820139.2020.18)
Background: Influenza A viruses (IAVs) induce acute respiratory disease and cause severe epidemics and pandemics. Since IAVs exhibit antigenic variation and genome reassortment, the development of broad-spectrum ...
Ohta M, Bannai H, Nemoto M, Kambayashi Y, Tamura N. Antibody Responses Against Equine Influenza Virus Induced by Concurrent and by Consecutive Use of an Inactivated Equine Influenza Virus Vaccine and a Modified Live Equine Herpesvirus Type 1 Vaccine in. J Equine Vet Sci. 2020 Nov;94:103221. Abstract
submitted by kickingbird at 8 days ago from J Equine Vet Sci. 2020 Nov;94:103221 (via https://www.sciencedirect.com/science/article/abs/pii/S07370)
An inactivated equine influenza virus (EIV) vaccine and a live equine herpesvirus type 1 (EHV-1) vaccine are usually administered concurrently to Thoroughbred racehorses in Japan. The objective of this ...
Shu B, Kirby MK, Warnes C, Sessions WM, Davis WG,. Detection and discrimination of influenza B Victoria lineage deletion variant viruses by real-time RT-PCR. Euro Surveill. 2020 Oct;25(41). Abstract
submitted by kickingbird at 9 days ago from Euro Surveill. 2020 Oct;25(41) (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
BackgroundDuring the 2016/17 influenza season, influenza B/VIC lineage variant viruses emerged with two (K162N163) or three (K162N163D164) amino acid (aa) deletions in the haemagglutinin (HA) protein. ...
Martin BE, Harris JD, Sun J, Koelle K, Brooke CB. Cellular co-infection can modulate the efficiency of influenza A virus production and shape the interferon response. PLoS Pathog. 2020 Oct 16;16(10):e1008974. Abstract
submitted by kickingbird at 9 days ago from PLoS Pathog. 2020 Oct 16;16(10):e1008974 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
During viral infection, the numbers of virions infecting individual cells can vary significantly over time and space. The functional consequences of this variation in cellular multiplicity of infection ...
Horman WSJ, Nguyen THO, Kedzierska K, Butler J, Sh. The Dynamics of the Ferret Immune Response During H7N9 Influenza Virus Infection. Front Immunol. 2020 Sep 24;11:559113. Abstract
submitted by kickingbird at 9 days ago from Front Immunol. 2020 Sep 24;11:559113 (via https://www.frontiersin.org/articles/10.3389/fimmu.2020.5591)
As the recent outbreak of SARS-CoV-2 has highlighted, the threat of a pandemic event from zoonotic viruses, such as the deadly influenza A/H7N9 virus subtype, continues to be a major global health concern. ...
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