Niu X, Wang H, Zhao L, Lian P, Bai Y, Li J, Qiao J. All-trans retinoic acid increases the pathogenicity of the H9N2 influenza virus in mice. Virol J. 2022 Jun 28;19(1):113. Abstract
submitted by kickingbird at 5 days ago from Virol J. 2022 Jun 28;19(1):113 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: The H9N2 virus can infect not only birds but also humans. The pathogenicity of H9N2 virus infection is determined by an excessive immune response in the lung. All-trans retinoic acid (ATRA), ...
Neveau MN, Zeller MA, Kaplan BS, Souza CK, Gauger. Genetic and Antigenic Characterization of an Expanding H3 Influenza A Virus Clade in U.S. Swine Visualized by Nextstrain. mSphere. 2022 Jun 29;7(3):e0099421. Abstract
submitted by kickingbird at 5 days ago from mSphere. 2022 Jun 29;7(3):e0099421 (via https://journals.asm.org/doi/10.1128/msphere.00994-21)
Defining factors that influence spatial and temporal patterns of influenza A virus (IAV) is essential to inform vaccine strain selection and strategies to reduce the spread of potentially zoonotic swine-origin ...
Huang WJ, Cheng YH, Tan MJ, Liu J, Li XY, Zeng XX,. Epidemiological and virological surveillance of influenza viruses in China during 2020-2021. Infect Dis Poverty. 2022 Jun 29;11(1):74. Abstract
submitted by kickingbird at 5 days ago from Infect Dis Poverty. 2022 Jun 29;11(1):74 (via https://idpjournal.biomedcentral.com/articles/10.1186/s40249)
Background: During the coronavirus disease 2019 (COVID-19) pandemic, seasonal influenza activity declined globally and remained below previous seasonal levels, but intensified in China since 2021. Preventive ...
Sewald K, Danov O. Infection of Human Precision-Cut Lung Slices with the Influenza Virus. Methods Mol Biol. 2022;2506:119-134. Abstract
submitted by kickingbird at 5 days ago from Methods Mol Biol. 2022;2506:119-134 (via https://link.springer.com/protocol/10.1007/978-1-0716-2364-0)
Viral infections are common causes of asthma exacerbations. To model these processes ex vivo, human precision-cut lung slices (PCLSs) can be used. Here we describe the infection of human PCLSs with the ...
Dai H, Zhou N, Chen M, Li G, Yu X, Su Y, Yi S, Hon. Assess transmissibility of different influenza subtypes: Based on a SEIABR model. Infect Genet Evol. 2022 Jun 22:105319. Abstract
submitted by kickingbird at 9 days ago from Infect Genet Evol. 2022 Jun 22:105319 (via https://www.sciencedirect.com/science/article/pii/S156713482)
Objective: Influenza is a worldwide public health problem which causes a serious economic and health burden. In order to provide a scientific basis for improving the prevention and control level of influenza, ...
Ertesv?g NU, Cox RJ, Lartey SL, Mohn KG, Brokstad. Seasonal influenza vaccination expands hemagglutinin-specific antibody breadth to older and future A/H3N2 viruses. NPJ Vaccines. 2022 Jun 24;7(1):67. Abstract
submitted by kickingbird at 9 days ago from NPJ Vaccines. 2022 Jun 24;7(1):67 (via https://www.nature.com/articles/s41541-022-00490-0)
History of influenza A/H3N2 exposure, especially childhood infection, shape antibody responses after influenza vaccination and infection, but have not been extensively studied. We investigated the breadth ...
Yuan Z, Zhou T, Zhang J, Zeng Q, Jiang D, Wei M, L. The Genomic Evolution and the Transmission Dynamics of H6N2 Avian Influenza A Viruses in Southern China. Viruses. 2022 May 26;14(6):1154. Abstract
submitted by kickingbird at 11 days ago from Viruses. 2022 May 26;14(6):1154 (via https://www.mdpi.com/1999-4915/14/6/1154)
In China, the broad prevalence of H6 subtype influenza viruses, increasingly detected in aquatic birds, promotes their exchange materials with other highly pathogenic human-infecting H5N1, H5N6, and H7N9 ...
Huang X, Huang J, Yin G, Cai Y, Chen M, Hu J, Feng. Identification of NP Protein-Specific B-Cell Epitopes for H9N2 Subtype of Avian Influenza Virus. Viruses. 2022 May 28;14(6):1172. Abstract
submitted by kickingbird at 11 days ago from Viruses. 2022 May 28;14(6):1172 (via https://www.mdpi.com/1999-4915/14/6/1172)
Avian Influenza (AI) caused by the H9N2 subtype of the avian influenza virus (AIV) poses a serious threat to both the poultry industry and to public health safety. NP is one of the major structural proteins ...
Yu M, Guo Y, Zhao L, Lu Y, Liu Q, Li Y, Deng L, Sh. D2I and F9Y Mutations in the NS1 Protein of Influenza A Virus Affect Viral Replication via Regulating Host Innate Immune Responses. Viruses. 2022 Jun 1;14(6):1206. Abstract
submitted by kickingbird at 11 days ago from Viruses. 2022 Jun 1;14(6):1206 (via https://www.mdpi.com/1999-4915/14/6/1206)
Influenza A viruses (IAV) modulate host antiviral responses to promote viral growth and pathogenicity. The non-structural (NS1) protein of influenza A virus has played an indispensable role in the inhibition ...
He D, Wang X, Wu H, Wang X, Yan Y, Li Y, Zhan T, H. Genome-Wide Reassortment Analysis of Influenza A H7N9 Viruses Circulating in China during 2013-2019. Viruses. 2022 Jun 9;14(6):1256. Abstract
submitted by kickingbird at 11 days ago from Viruses. 2022 Jun 9;14(6):1256 (via https://www.mdpi.com/1999-4915/14/6/1256)
Reassortment with the H9N2 virus gave rise to the zoonotic H7N9 avian influenza virus (AIV), which caused more than five outbreak waves in humans, with high mortality. The frequent exchange of genomic ...
Panzarin V, Marciano S, Fortin A, Brian I, D´. Redesign and Validation of a Real-Time RT-PCR to Improve Surveillance for Avian Influenza Viruses of the H9 Subtype. Viruses. 2022 Jun 10;14(6):1263. Abstract
submitted by kickingbird at 11 days ago from Viruses. 2022 Jun 10;14(6):1263 (via https://www.mdpi.com/1999-4915/14/6/1263)
Avian influenza viruses of the H9 subtype cause significant losses to poultry production in endemic regions of Asia, Africa and the Middle East and pose a risk to human health. The availability of reliable ...
Pekarek MJ, Petro-Turnquist EM, Rubrum A, Webby RJ. Expanding Mouse-Adapted Yamagata-like Influenza B Viruses in Eggs Enhances In Vivo Lethality in BALB/c Mice. Viruses. 2022 Jun 14;14(6):1299. Abstract
submitted by kickingbird at 11 days ago from Viruses. 2022 Jun 14;14(6):1299 (via https://www.mdpi.com/1999-4915/14/6/1299)
Despite the yearly global impact of influenza B viruses (IBVs), limited host range has been a hurdle to developing a readily accessible small animal disease model for vaccine studies. Mouse-adapting IBV ...
Praena B, Wan XF. Influenza Virus Infections in Polarized Cells. Viruses. 2022 Jun 15;14(6):1307. Abstract
submitted by kickingbird at 11 days ago from Viruses. 2022 Jun 15;14(6):1307 (via https://www.mdpi.com/1999-4915/14/6/1307)
In humans and other mammals, the respiratory tract is represented by a complex network of polarized epithelial cells, forming an apical surface facing the external environment and a basal surface attached ...
Khalil AM, Kojima I, Fukunaga W, Okajima M, Mitara. Improved method for avian influenza virus isolation from environmental water samples. Transbound Emerg Dis. 2022 Jun 23. Abstract
submitted by kickingbird at 12 days ago from Transbound Emerg Dis. 2022 Jun 23 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14639)
Environmental water-targeted surveillance of migratory aquatic birds at overwintering sites is potentially one of the most effective approaches for understanding the ecology of avian influenza viruses ...
Cheng J, Tao J, Li B, Shi Y, Liu H. Swine influenza virus triggers ferroptosis in A549 cells to enhance virus replication. Virol J. 2022 Jun 17;19(1):104. Abstract
submitted by kickingbird at 13 days ago from Virol J. 2022 Jun 17;19(1):104 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: Recently, Influenza A virus (IAV) has been shown to activate several programmed cell death pathways that play essential roles in host defense. Indeed, cell death caused by viral infection may ...
Pohlmann A, King J, Fusaro A, Zecchin B, Banyard A. Has Epizootic Become Enzootic? Evidence for a Fundamental Change in the Infection Dynamics of Highly Pathogenic Avian Influenza in Europe, 2021. mBio. 2022 Jun 21:e0060922. Abstract
submitted by kickingbird at 13 days ago from mBio. 2022 Jun 21:e0060922 (via https://journals.asm.org/doi/10.1128/mbio.00609-22)
Phylogenetic evidence from the recent resurgence of high-pathogenicity avian influenza (HPAI) virus subtype H5N1, clade 220.127.116.11b, observed in European wild birds and poultry since October 2021, suggests ...
Dean DA, Klechka L, Hossain E, Parab AR, Eaton K,. Spatial Metabolomics Reveals Localized Impact of Influenza Virus Infection on the Lung Tissue Metabolome. mSystems. 2022 Jun 22:e0035322. Abstract
submitted by kickingbird at 13 days ago from mSystems. 2022 Jun 22:e0035322 (via https://journals.asm.org/doi/10.1128/msystems.00353-22)
The influenza virus (IAV) is a major cause of respiratory disease, with significant infection increases in pandemic years. Vaccines are a mainstay of IAV prevention but are complicated by IAV's vast strain ...
Sun W, Cheng SSM, Lam KNT, Kwan TC, Wong RWK, Lau. Natural Reassortment of Eurasian Avian-Like Swine H1N1 and Avian H9N2 Influenza Viruses in Pigs, China. Emerg Infect Dis. 2022 Jul;28(7):1509-1512. Abstract
submitted by kickingbird at 13 days ago from Emerg Infect Dis. 2022 Jul;28(7):1509-1512 (via https://wwwnc.cdc.gov/eid/article/28/7/22-0642_article)
Several zoonotic influenza A viruses detected in humans contain genes derived from avian H9N2 subtypes. We uncovered a Eurasian avian-like H1N1 swine influenza virus with polymerase basic 1 and matrix ...
Moise L, Meyers LM, Jang H, Grizotte-Lake M, Boyle. Novel H7N9 influenza immunogen design enhances mobilization of seasonal influenza T cell memory in H3N2 pre-immune mice. Hum Vaccin Immunother. 2022 Jun 15:2082191. Abstract
submitted by kickingbird at Jun, 18, 2022 from Hum Vaccin Immunother. 2022 Jun 15:2082191 (via https://www.tandfonline.com/doi/full/10.1080/21645515.2022.2)
Strategies that improve influenza vaccine immunogenicity are critical for the development of vaccines for pandemic preparedness. Hemagglutinin (HA)-specific CD4+ T cell epitopes support protective B cell ...
Zhu R, Xu S, Sun W, Li Q, Wang S, Shi H, Liu X. HA gene amino acid mutations contribute to antigenic variation and immune escape of H9N2 influenza virus. Vet Res. 2022 Jun 15;53(1):43. Abstract
submitted by kickingbird at Jun, 18, 2022 from Vet Res. 2022 Jun 15;53(1):43 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
Based on differences in the amino acid sequence of the protein haemagglutinin (HA), the H9N2 avian influenza virus (H9N2 virus) has been clustered into multiple lineages, and its rapidly ongoing evolution ...
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