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2024-11-21 19:50:06
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Sun J, Zheng T, Jia M, Wang Y, Yang J, Liu Y, Yang. Dual receptor-binding, infectivity, and transmissibility of an emerging H2N2 low pathogenicity avian influenza virus. Nat Commun. 2024 Nov 19;15(1):10012.  Abstract  
submitted by kickingbird at 10 hours ago from Nat Commun. 2024 Nov 19;15(1):10012 (via https://www.nature.com/articles/s41467-024-54374-z)
The 1957 H2N2 influenza pandemic virus [A(H2N2)pdm1957] has disappeared from humans since 1968, while H2N2 avian influenza viruses (AIVs) are still circulating in birds. It is necessary to reveal the recurrence ...

Reid SM, Coward VJ, James J, Hansen RDE, Birch C,. Validation of a reduction in time for avian influenza virus isolation using specific pathogen-free embryonated chicken eggs. Vet Rec. 2024 Nov 19:e4842.  Abstract  
submitted by kickingbird at 10 hours ago from Vet Rec. 2024 Nov 19:e4842 (via https://bvajournals.onlinelibrary.wiley.com/doi/10.1002/vetr)
Background: The international gold standard for avian influenza virus (AIV) diagnosis is virus isolation (VI) in specific pathogen-free embryonated chicken eggs (ECEs). AIV isolation typically involves ...

Vu TH, Kim C, Truong AD, Kim JM, Lillehoj HS, Hong. Unveiling the role of long non-coding RNAs in chicken immune response to highly pathogenic avian influenza H5N1 infection. Poult Sci. 2024 Nov 6;104(1):104524.  Abstract  
submitted by kickingbird at 10 hours ago from Poult Sci. 2024 Nov 6;104(1):104524 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Avian influenza viruses (AIVs) pose a significant threat to global poultry production, necessitating effective control strategies to mitigate economic losses and ensure animal welfare. Long non-coding ...

Marie-Cécile Dupas, etc.,al. [preprint]Global risk mapping of highly pathogenic avian influenza H5N1 and H5Nx in the light of epidemic episodes occurring from 2020 onward. https://doi.org/10.1101/2024.11.15.623755.  Abstract  
submitted by kickingbird at 1 days ago from https://doi.org/10.1101/2024.11.15.623755 (via https://www.biorxiv.org/content/10.1101/2024.11.15.623755v1)
Avian influenza (AI) is a highly contagious viral disease affecting poultry and wild water birds, posing significant global challenges due to its high mortality rates and economic impacts. Highly pathogenic ...

Akanbi OB, Alaka OO, Olaifa OS, Meseko CA, Inuwa B. Pathology and molecular detection of influenza A subtype H9N2 virus in commercial poultry in Nigeria, 2024. Open Vet J. 2024 Sep;14(9):2381-2391.  Abstract  
submitted by kickingbird at 1 days ago from Open Vet J. 2024 Sep;14(9):2381-2391 (via https://www.bibliomed.org/?mno=204059)
Background: After the first Avian Influenza H5N1 outbreak in Nigerian poultry in 2006, subsequent waves of outbreaks occurred, causing substantial losses. Despite effective control measures by 2008, a ...

Goto T, Kawai N, Bando T, Takasaki Y, Shindo S, Sa. Virological and Clinical Outcomes of Influenza Outpatients Treated With Baloxavir, Oseltamivir, or Laninamivir in the 2023-2024 Season. Influenza Other Respir Viruses. 2024 Nov;18(11):e7.  Abstract  
submitted by kickingbird at 1 days ago from Influenza Other Respir Viruses. 2024 Nov;18(11):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70042)
Background: Clinical data on patients infected with influenza B Victoria (BV) after the approval of baloxavir is lacking.Methods: This observational study of the Japanese 2023-2024 influenza season analyzed ...

Alexey Markin, Catherine A Macken, Amy L Baker,. [preprint]Revealing reassortment in influenza A viruses with TreeSort. https://doi.org/10.1101/2024.11.15.623781.  Abstract  
submitted by kickingbird at 3 days ago from https://doi.org/10.1101/2024.11.15.623781 (via https://www.biorxiv.org/content/10.1101/2024.11.15.623781v1)
Reassortment among influenza A viruses (IAV) facilitates genomic evolution and has been associated with interspecies transmission and pandemics. We introduce a novel tool called TreeSort that accurately ...

Chloe Qingzhou Huang, etc.,al. [preprint]Digitally immune optimised haemagglutinin with nanocage plug-and-display elicits broadly neutralising pan-H5 influenza subtype vaccine responses. https://doi.org/10.1101/2024.11.14.623359.  Abstract  
submitted by kickingbird at 3 days ago from https://doi.org/10.1101/2024.11.14.623359 (via https://www.biorxiv.org/content/10.1101/2024.11.14.623359v1)
The increasing global spread of the highly pathogenic avian influenza (HPAI) A/H5 viruses poses a serious public health threat. Circulating clade 2.3.4.4b viruses have demonstrated rapid transcontinental ...

Pari H Baker, etc.,al. [preprint]Intramammary infection of bovine H5N1 influenza virus in ferrets leads to transmission and mortality in suckling neonates. https://doi.org/10.1101/2024.11.15.623885.  Abstract  
submitted by kickingbird at 3 days ago from https://doi.org/10.1101/2024.11.15.623885 (via https://www.biorxiv.org/content/10.1101/2024.11.15.623885v2)
The spread of H5N1 clade 2.3.4.4b in dairy herds raises concerns about zoonotic transmission due to the high viral load in milk, a key point of contact between livestock and humans. H5N1 clade 2.3.4.4b ...

Izumi H. Conformational Variability Prediction of Influenza Virus Hemagglutinins with Amino Acid Mutations Using Supersecondary Structure Code. Methods Mol Biol. 2025;2870:63-78.  Abstract  
submitted by kickingbird at 4 days ago from Methods Mol Biol. 2025;2870:63-78 (via https://link.springer.com/protocol/10.1007/978-1-0716-4213-9)
Supersecondary structure code (SSSC), which is represented as a conformation term using the letters "H," "S," "T," and "D" for each amino acid peptide unit, can be utilized to look up supersecondary structure ...

Chrzastek K, Kapczynski DR. In Silico Genomic Analysis of Avian Influenza Viruses Isolated From Marine Seal Colonies. Pathogens. 2024; 13(11):1009.  Abstract  
submitted by kickingbird at 4 days ago from Pathogens. 2024; 13(11):1009 (via https://www.mdpi.com/2076-0817/13/11/1009)
Genetically diverse avian influenza viruses (AIVs) are maintained in wild aquatic birds with increasingly frequent spillover into mammals, yet these represent a small proportion of the overall detections. ...

Thi Hao Vu, etc.,al. Unveiling the role of long non-coding RNAs in chicken immune response to highly pathogenic avian influenza H5N1 infection. Poultry Science.  Abstract  
submitted by kickingbird at 4 days ago from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
Avian influenza viruses (AIVs) pose a significant threat to global poultry production, necessitating effective control strategies to mitigate economic losses and ensure animal welfare. Long non-coding ...

Zhang Shuxia, Liu Jia, Tan Min, Yang Lei, Li Xiyan. Characteristics of Highly Pathogenic Avian Influenza A(H5) Clade 2.3.4.4b Viruses in China, 2010~2023. Disease Surveillance, 2024.  Abstract  
submitted by kickingbird at 6 days ago from Disease Surveillance, 2024 (via http://www.jbjc.org/)
Objectives Based on the global spread of highly pathogenic avian influenza A(H5) clade 2.3.4.4b viruses, this study analyzed the epidemic and phylogenetic evolution characteristics of clade 2.3.4.4b viruses ...

Zhou Y, Jin L, Lai X, Li Y, Sheng L, Xie G, Fang J. Adverse events associated with oseltamivir and baloxavir marboxil in against influenza virus therapy: A pharmacovigilance study using the FAERS database. PLoS One. 2024 Nov 13;19(11):e0308998.  Abstract  
submitted by kickingbird at 6 days ago from PLoS One. 2024 Nov 13;19(11):e0308998 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Background: Influenza virus is a widespread pathogen that poses significant health risks to humans. Oseltamivir and Baloxavir Marboxil are commonly utilized medications for both treating and preventing ...

Dadonaite B, Ahn JJ, Ort JT, Yu J, Furey C, Dosey. Deep mutational scanning of H5 hemagglutinin to inform influenza virus surveillance. PLoS Biol. 2024 Nov 12;22(11):e3002916.  Abstract  
submitted by kickingbird at 7 days ago from PLoS Biol. 2024 Nov 12;22(11):e3002916 (via https://journals.plos.org/plosbiology/article?id=10.1371/jou)
H5 influenza is considered a potential pandemic threat. Recently, H5 viruses belonging to clade 2.3.4.4b have caused large outbreaks in avian and multiple nonhuman mammalian species. Previous studies have ...

Xu J, Luo Q, Huang Y, Li J, Ye W, Yan R, Zhou X, H. Influenza neuraminidase mutations and resistance to neuraminidase inhibitors. Emerg Microbes Infect. 2024 Nov 12:2429627.  Abstract  
submitted by kickingbird at 7 days ago from Emerg Microbes Infect. 2024 Nov 12:2429627 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Mutations in influenza virus neuraminidase (NA) can lead to viral resistance to NA inhibitors (NAIs). To update global influenza NA mutations and resistance to NAIs, we investigated epidemic information ...

Ye Ge, etc.,al. Epidemic of wild-origin H1NX avian influenza viruses in Anhui, China. DOI: 10.1186/s40249-017-0304-4.  Abstract  
submitted by kickingbird at 8 days ago from DOI: 10.1186/s40249-017-0304-4 (via https://rs.yiigle.com/cmaid/1006054)
Background:As the natural hosts of avian influenza viruses (AIVs), aquatic and migratory birds provide a gene pool for genetic transfer among species and across species, forming transient "genome constellations." ...

Liang Lijun, etc.,al. Gene analysis of polymerase basic protein 2 variant strains of influenza virus H1N1pdm09 subtype in Guangdong province. DOI: 10.3760/cma.j.cn112866-20240521-00084.  Abstract  
submitted by kickingbird at 8 days ago from DOI: 10.3760/cma.j.cn112866-20240521-00084 (via https://rs.yiigle.com/cmaid/1518786)
Objective To understand the molecular characteristics of the mutant strain of polymerase basic protein 2 (PB2) gene of influenza A (H1N1pdm) in Guangdong province, and to explore its specific molecular ...

Vincent C Calhoun, Eneida L Hatcher, Linda Yankie,. Influenza sequence validation and annotation using VADR. Database, 2024.  Abstract  
submitted by kickingbird at 9 days ago from Database, 2024 (via https://academic.oup.com/database/article/doi/10.1093/databa)
Tens of thousands of influenza sequences are deposited into the GenBank database each year. The software tool FLu ANnotation tool (FLAN) has been used by GenBank since 2007 to validate and annotate incoming ...

Sultankulova KT, Argimbayeva TU, Aubakir NA, Bopi. Reassortants of the Highly Pathogenic Influenza Virus A/H5N1 Causing Mass Swan Mortality in Kazakhstan from 2023 to 2024. Animals. 2024; 14(22):3211.  Abstract  
submitted by kickingbird at 9 days ago from Animals. 2024; 14(22):3211 (via https://www.mdpi.com/2076-2615/14/22/3211)
In the winter of 2023/2024, the mass death of swans was observed on Lake Karakol on the eastern coast of the Caspian Sea. From 21 December 2023 to 25 January 2024, 1132 swan corpses (Cygnus olor, Cygnus ...

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