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2019-1-21 8:26:49

Bedford JG, O´Keeffe M, Reading PC, Wakim LM. Rapid interferon independent expression of IFITM3 following T cell activation protects cells from influenza virus infection. PLoS One. 2019 Jan 16;14(1):e0210132.  Abstract  
submitted by kickingbird at 3 days ago from PLoS One. 2019 Jan 16;14(1):e0210132 (via https://www.ncbi.nlm.nih.gov/pubmed/30650117)
Interferon-induced transmembrane protein 3 (IFITM3) is a potent antiviral protein that enhances cellular resistance to a variety of pathogens, including influenza virus. Classically defined as an interferon-stimulated ...

Liu L, Wang T, Wang M, Tong Q, Sun Y, Pu J, et al. Recombinant turkey herpesvirus expressing H9 hemagglutinin providing protection against H9N2 avian influenza. Virology. 2019 Jan 4;529:7-15.  Abstract  
submitted by kickingbird at 5 days ago from Virology. 2019 Jan 4;529:7-15 (via https://www.ncbi.nlm.nih.gov/pubmed/30641481)
H9N2 avian influenza viruses (AIVs) were prevailing in chickens, causing great economic losses and public health threats. In this study, turkey herpesviruses (HVT) was cloned as an infectious bacterial ...

Li J, et al. MOV10 sequesters the RNP of influenza A virus in the cytoplasm and is antagonized by viral NS1 protein. Biochem J. 2019 Jan 7.  Abstract  
submitted by kickingbird at 7 days ago from Biochem J. 2019 Jan 7 (via https://www.ncbi.nlm.nih.gov/pubmed/30617221)
MOV10 has emerged as an important host antiviral factor. MOV10 not only inhibits various viruses including human immunodeficiency virus type 1, hepatitis C virus and vesicular stomatitis virus, it also ...

Qin J, Peng O, Shen X, Gong L, Xue C, Cao Y. Multiple amino acid substitutions involved in the adaption of three avian-origin H7N9 influenza viruses in mice. Virol J. 2019 Jan 8;16(1):3.  Abstract  
submitted by kickingbird at 7 days ago from Virol J. 2019 Jan 8;16(1):3 (via https://www.ncbi.nlm.nih.gov/pubmed/30621708)
BACKGROUND: Avian influenza A H7N9 virus has caused five outbreak waves of human infections in China since 2013 and posed a dual challenge to public health and poultry industry. The number of reported ...

Qin C, Li W, Li Q, Yin W, Zhang X, et al. Real-time dissection of dynamic uncoating of individual influenza viruses. Proc Natl Acad Sci U S A. 2019 Jan 9..  Abstract  
submitted by kickingbird at 7 days ago from Proc Natl Acad Sci U S A. 2019 Jan 9. (via https://www.ncbi.nlm.nih.gov/pubmed/30626642)
Uncoating is an obligatory step in the virus life cycle that serves as an antiviral target. Unfortunately, it is challenging to study viral uncoating due to methodology limitations for detecting this transient ...

Evseev D, Magor KE. Innate Immune Responses to Avian Influenza Viruses in Ducks and Chickens. Vet Sci. 2019 Jan 10;6(1)..  Abstract  
submitted by kickingbird at 7 days ago from Vet Sci. 2019 Jan 10;6(1). (via https://www.ncbi.nlm.nih.gov/pubmed/30634569)
Mallard ducks are important natural hosts of low pathogenic avian influenza (LPAI) viruses and many strains circulate in this reservoir and cause little harm. Some strains can be transmitted to other hosts, ...

Hao M, et al. The PA Subunit of the Influenza Virus Polymerase Complex Affects Replication and Airborne Transmission of the H9N2 Subtype Avian Influenza Virus. Viruses. 2019 Jan 9;11(1).  Abstract  
submitted by kickingbird at 7 days ago from Viruses. 2019 Jan 9;11(1) (via https://www.ncbi.nlm.nih.gov/pubmed/30634394)
The polymerase acidic (PA) protein is the third subunit of the influenza A virus polymerase. In recent years, studies have shown that PA plays an important role in overcoming the host species barrier and ...

Souvestre M, Guinat C, Niqueux E, et al. Role of Backyard Flocks in Transmission Dynamics of Highly Pathogenic Avian Influenza A(H5N8) Clade, France, 2016-2017. Emerg Infect Dis. 2019 Mar 17;25(3).  Abstract  
submitted by kickingbird at 7 days ago from Emerg Infect Dis. 2019 Mar 17;25(3) (via https://www.ncbi.nlm.nih.gov/pubmed/30623754)
Highly pathogenic avian influenza A(H5N8) clade spread in France during 2016-2017. We assessed the biosecurity and avian influenza virus infection status of 70 backyard flocks near H5N8-infected ...

Shkurupy VA, et al. Changes in the Structure of Mouse Kidney in the Acute Period after Infection with Influenza Viruses A/H5N1 and A/H1N1. Bull Exp Biol Med. 2019 Jan 9.  Abstract  
submitted by kickingbird at 7 days ago from Bull Exp Biol Med. 2019 Jan 9 (via https://www.ncbi.nlm.nih.gov/pubmed/30627911)
Changes in the kidney structure in outbred and inbred male BALB/c mice were analyzed in the acute period after infection with influenza viruses A/H5N1 (10 MLD50; 10 days) and A/H1N1 (1 MLD50; 30 days). ...

Zhuang J, Zang N, Ye C, Xu F. Lethal Avian Influenza A (H5N1) Virus Replicates in Pontomedullary Chemosensitive Neurons and Depresses Hypercapnic Ventilatory Response in Mice. Am J Physiol Lung Cell Mol Physiol. 2019 Jan 10.  Abstract  
submitted by kickingbird at 7 days ago from Am J Physiol Lung Cell Mol Physiol. 2019 Jan 10 (via https://www.ncbi.nlm.nih.gov/pubmed/30628490)
The highly pathogenic H5N1 (HK483) viral infection causes a depressed hypercapnic ventilatory response (dHCVR, 20%↓) at 2 days post-infection (dpi) and death at 7 dpi in mice, but the relevant mechanisms ...

Lomakina NF, et al. Three Mutations in the Stalk Region of Hemagglutinin Affect the pH of Fusion and Pathogenicity of H5N1 Influenza Virus. Mol Biol (Mosk). 2018 Nov-Dec;52(6):1029-1037.  Abstract  
submitted by kickingbird at 7 days ago from Mol Biol (Mosk). 2018 Nov-Dec;52(6):1029-1037 (via https://www.ncbi.nlm.nih.gov/pubmed/30633245)
Previously, an attenuated variant Ku/at was obtained from the highly pathogenic avian influenza virus A/chicken/Kurgan/3/2005 (H5N1) by a reverse selection method aimed at increasing the virus resistance ...

Lam JH, Baumgarth N. The Multifaceted B Cell Response to Influenza Virus. J Immunol. 2019 Jan 15;202(2):351-359.  Abstract  
submitted by kickingbird at 12 days ago from J Immunol. 2019 Jan 15;202(2):351-359 (via https://www.ncbi.nlm.nih.gov/pubmed/30617116)
Protection from yearly recurring, highly acute infections with a pathogen that rapidly and continuously evades previously induced protective neutralizing Abs, as seen during seasonal influenza virus infections, ...

Kuroki T, Osari S, Nagata K, Kawaguchi A. Influenza A Virus NS1 Protein Suppresses JNK1-Dependent Autophagosome Formation Mediated by Rab11a Recycling Endosomes. Front Microbiol. 2018 Dec 14;9:3120..  Abstract  
submitted by kickingbird at 12 days ago from Front Microbiol. 2018 Dec 14;9:3120. (via https://www.ncbi.nlm.nih.gov/pubmed/30619194)
Autophagy is an essential process for cellular metabolism and homeostasis, but also functions as one of innate immune responses against pathogen infection. However, in contrast to cellular metabolism and ...

Dadak M, et al. Varying Patterns of CNS Imaging in Influenza A Encephalopathy in Childhood. Clin Neuroradiol. 2019 Jan 4.  Abstract  
submitted by kickingbird at 14 days ago from Clin Neuroradiol. 2019 Jan 4 (via https://www.ncbi.nlm.nih.gov/pubmed/30610262)
PURPOSE: The brain imaging findings in children with neurological complications associated with influenza A infections are presented and analyzed and pathological imaging changes including atypical intracerebral ...

Saito S, et al. Development and evaluation of a new real-time RT-PCR assay for detecting the latest H9N2 influenza viruses capable of causing human infection. Microbiol Immunol. 2019 Jan 1..  Abstract  
submitted by kickingbird at Jan, 4, 2019 from Microbiol Immunol. 2019 Jan 1. (via https://www.ncbi.nlm.nih.gov/pubmed/30599081)
The H9N2 subtype of avian influenza A viruses (AIVs) has spread among domestic poultry and wild bird worldwide. H9N2 AIV is sporadically transmitted to humans from avian species. A total of 42 laboratory-confirmed ...

Zhou X, Yin R, Kwoh CK, Zheng J. A context-free encoding scheme of protein sequences for predicting antigenicity of diverse influenza A viruses. BMC Genomics. 2018 Dec 31;19.  Abstract  
submitted by kickingbird at Jan, 4, 2019 from BMC Genomics. 2018 Dec 31;19 (via https://www.ncbi.nlm.nih.gov/pubmed/30598102)
BACKGROUND: The evolution of influenza A viruses leads to the antigenic changes. Serological diagnosis of the antigenicity is usually labor-intensive, time-consuming and not suitable for early-stage detection. ...

Peng Q, et al. Impact of the variations in potential glycosylation sites of the hemagglutinin of H9N2 influenza virus. Virus Genes. 2018 Dec 29..  Abstract  
submitted by kickingbird at Jan, 1, 2019 from Virus Genes. 2018 Dec 29. (via https://www.ncbi.nlm.nih.gov/pubmed/30594968)
Variations in the potential glycosylation sites were observed in hemagglutinin (HA) sequences of H9N2 avian influenza virus isolated in China, deposited in the Influenza Virus Resource of NCBI before 2017, ...

Li Z, et al. A novel linear epitope crossing Group 1 and Group 2 influenza A viruses located in the helix A of HA2 derived from H7N9. Vet Microbiol. 2019 Jan;228:39-44..  Abstract  
submitted by kickingbird at Dec, 30, 2018 from Vet Microbiol. 2019 Jan;228:39-44. (via https://www.ncbi.nlm.nih.gov/pubmed/30593378)
In this research, four monoclonal antibodies (mAbs) were first generated as an immunogen by using the GST fusion protein that carries the fusion peptide and helix A derived from H7N9 influenza A virus ...

Wang Z, et al. Pre-exposure with influenza A virus A/WSN/1933(H1N1) resulted in viral shedding reduction from pigs challenged with either swine H1N1 or H3N2 virus. Vet Microbiol. 2019 Jan;228:26-31.  Abstract  
submitted by kickingbird at Dec, 30, 2018 from Vet Microbiol. 2019 Jan;228:26-31 (via https://www.ncbi.nlm.nih.gov/pubmed/30593376)
There is an urgent need to develop a broad-spectrum vaccine that can effectively prevent or eliminate the spread of co-circulating swine influenza virus strains in multiple lineages or subtypes. We describe ...

An SH, Lee CY, Choi JG, Lee YJ, Kim JH, Kwon HJ. Generation of highly productive and mammalian nonpathogenic recombinant H9N2 avian influenza viruses by optimization of 3´end promoter and NS genome. Vet Microbiol. 2019 Jan;228:213-218..  Abstract  
submitted by kickingbird at Dec, 30, 2018 from Vet Microbiol. 2019 Jan;228:213-218. (via https://www.ncbi.nlm.nih.gov/pubmed/30593370)
We developed A/PR/8/34 (PR8) virus-based reverse genetics system in which six internal genes of PR8 and attenuated hemagglutinin and intact neuraminidase genes of field avian influenza viruses (AIVs) have ...

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