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2024-11-21 22:52:29
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Sun J, Zheng T, Jia M, Wang Y, Yang J, Liu Y, Yang. Dual receptor-binding, infectivity, and transmissibility of an emerging H2N2 low pathogenicity avian influenza virus. Nat Commun. 2024 Nov 19;15(1):10012.  Abstract  
submitted by kickingbird at 13 hours ago from Nat Commun. 2024 Nov 19;15(1):10012 (via https://www.nature.com/articles/s41467-024-54374-z)
The 1957 H2N2 influenza pandemic virus [A(H2N2)pdm1957] has disappeared from humans since 1968, while H2N2 avian influenza viruses (AIVs) are still circulating in birds. It is necessary to reveal the recurrence ...

Reid SM, Coward VJ, James J, Hansen RDE, Birch C,. Validation of a reduction in time for avian influenza virus isolation using specific pathogen-free embryonated chicken eggs. Vet Rec. 2024 Nov 19:e4842.  Abstract  
submitted by kickingbird at 13 hours ago from Vet Rec. 2024 Nov 19:e4842 (via https://bvajournals.onlinelibrary.wiley.com/doi/10.1002/vetr)
Background: The international gold standard for avian influenza virus (AIV) diagnosis is virus isolation (VI) in specific pathogen-free embryonated chicken eggs (ECEs). AIV isolation typically involves ...

Vu TH, Kim C, Truong AD, Kim JM, Lillehoj HS, Hong. Unveiling the role of long non-coding RNAs in chicken immune response to highly pathogenic avian influenza H5N1 infection. Poult Sci. 2024 Nov 6;104(1):104524.  Abstract  
submitted by kickingbird at 13 hours ago from Poult Sci. 2024 Nov 6;104(1):104524 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Avian influenza viruses (AIVs) pose a significant threat to global poultry production, necessitating effective control strategies to mitigate economic losses and ensure animal welfare. Long non-coding ...

WHO. Influenza at the human-animal interface summary and assessment, 1 November 2024. WHO.  Abstract  
submitted by kickingbird at 13 hours ago from WHO (via https://www.who.int/publications/m/item/influenza-at-the-hum)
From 28 September to 1 November 2024, the detection of influenza A(H5) virus in 30 humans and influenza A(H9N2) virus in one human were reported officially.? New human cases: From 28 September to 1 November ...

Marie-Cécile Dupas, etc.,al. [preprint]Global risk mapping of highly pathogenic avian influenza H5N1 and H5Nx in the light of epidemic episodes occurring from 2020 onward. https://doi.org/10.1101/2024.11.15.623755.  Abstract  
submitted by kickingbird at 1 days ago from https://doi.org/10.1101/2024.11.15.623755 (via https://www.biorxiv.org/content/10.1101/2024.11.15.623755v1)
Avian influenza (AI) is a highly contagious viral disease affecting poultry and wild water birds, posing significant global challenges due to its high mortality rates and economic impacts. Highly pathogenic ...

Akanbi OB, Alaka OO, Olaifa OS, Meseko CA, Inuwa B. Pathology and molecular detection of influenza A subtype H9N2 virus in commercial poultry in Nigeria, 2024. Open Vet J. 2024 Sep;14(9):2381-2391.  Abstract  
submitted by kickingbird at 1 days ago from Open Vet J. 2024 Sep;14(9):2381-2391 (via https://www.bibliomed.org/?mno=204059)
Background: After the first Avian Influenza H5N1 outbreak in Nigerian poultry in 2006, subsequent waves of outbreaks occurred, causing substantial losses. Despite effective control measures by 2008, a ...

Goto T, Kawai N, Bando T, Takasaki Y, Shindo S, Sa. Virological and Clinical Outcomes of Influenza Outpatients Treated With Baloxavir, Oseltamivir, or Laninamivir in the 2023-2024 Season. Influenza Other Respir Viruses. 2024 Nov;18(11):e7.  Abstract  
submitted by kickingbird at 1 days ago from Influenza Other Respir Viruses. 2024 Nov;18(11):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70042)
Background: Clinical data on patients infected with influenza B Victoria (BV) after the approval of baloxavir is lacking.Methods: This observational study of the Japanese 2023-2024 influenza season analyzed ...

Haman KH, Pearson SF, Brown J, Frisbie LA, Penhall. A comprehensive epidemiological approach documenting an outbreak of H5N1 highly pathogenic avian influenza virus clade 2.3.4.4b among gulls, terns, and harbor seals in the Northeastern Pacific. Front Vet Sci. 2024 Nov 1;11:1483922.  Abstract  
submitted by kickingbird at 2 days ago from Front Vet Sci. 2024 Nov 1;11:1483922 (via https://www.frontiersin.org/journals/veterinary-science/arti)
Highly pathogenic avian influenza viruses (HPAIV) H5N1 clade 2.3.4.4b continue to have unprecedented global impacts on wild birds and mammals, with especially significant mortality observed in colonial ...

Youk S, Lee DH, Swayne DE, Killian ML, Torchetti M. Novel reassortant H2N2 low pathogenic avian influenza virus in live bird markets in the Northeastern United States, 2019-2023. Avian Pathol. 2024 Nov 18:1-7.  Abstract  
submitted by kickingbird at 2 days ago from Avian Pathol. 2024 Nov 18:1-7 (via https://www.tandfonline.com/doi/full/10.1080/03079457.2024.2)
The H2N2 avian influenza viruses (AIV) have been reported in the Northeast United States of America (USA) live bird market (LBM) system since 2014. In this study, we investigated the genetic evolution ...

Alexey Markin, Catherine A Macken, Amy L Baker,. [preprint]Revealing reassortment in influenza A viruses with TreeSort. https://doi.org/10.1101/2024.11.15.623781.  Abstract  
submitted by kickingbird at 4 days ago from https://doi.org/10.1101/2024.11.15.623781 (via https://www.biorxiv.org/content/10.1101/2024.11.15.623781v1)
Reassortment among influenza A viruses (IAV) facilitates genomic evolution and has been associated with interspecies transmission and pandemics. We introduce a novel tool called TreeSort that accurately ...

Chloe Qingzhou Huang, etc.,al. [preprint]Digitally immune optimised haemagglutinin with nanocage plug-and-display elicits broadly neutralising pan-H5 influenza subtype vaccine responses. https://doi.org/10.1101/2024.11.14.623359.  Abstract  
submitted by kickingbird at 4 days ago from https://doi.org/10.1101/2024.11.14.623359 (via https://www.biorxiv.org/content/10.1101/2024.11.14.623359v1)
The increasing global spread of the highly pathogenic avian influenza (HPAI) A/H5 viruses poses a serious public health threat. Circulating clade 2.3.4.4b viruses have demonstrated rapid transcontinental ...

Pari H Baker, etc.,al. [preprint]Intramammary infection of bovine H5N1 influenza virus in ferrets leads to transmission and mortality in suckling neonates. https://doi.org/10.1101/2024.11.15.623885.  Abstract  
submitted by kickingbird at 4 days ago from https://doi.org/10.1101/2024.11.15.623885 (via https://www.biorxiv.org/content/10.1101/2024.11.15.623885v2)
The spread of H5N1 clade 2.3.4.4b in dairy herds raises concerns about zoonotic transmission due to the high viral load in milk, a key point of contact between livestock and humans. H5N1 clade 2.3.4.4b ...

Frutos AM, Ahmad HM, Ujamaa D, et al. Underutilization of Influenza Antiviral Treatment Among Children and Adolescents at Higher Risk for Influenza-Associated Complications - United States, 2023-2024. MMWR Morb Mortal Wkly Rep 2024;73:1022–1029.  Abstract  
submitted by kickingbird at 5 days ago from MMWR Morb Mortal Wkly Rep 2024;73:1022–1029 (via https://www.cdc.gov/mmwr/volumes/73/wr/mm7345a2.htm)
Annually, tens of thousands of U.S. children and adolescents are hospitalized with seasonal influenza virus infection. Both influenza vaccination and early initiation of antiviral treatment can reduce ...

Izumi H. Conformational Variability Prediction of Influenza Virus Hemagglutinins with Amino Acid Mutations Using Supersecondary Structure Code. Methods Mol Biol. 2025;2870:63-78.  Abstract  
submitted by kickingbird at 5 days ago from Methods Mol Biol. 2025;2870:63-78 (via https://link.springer.com/protocol/10.1007/978-1-0716-4213-9)
Supersecondary structure code (SSSC), which is represented as a conformation term using the letters "H," "S," "T," and "D" for each amino acid peptide unit, can be utilized to look up supersecondary structure ...

Chrzastek K, Kapczynski DR. In Silico Genomic Analysis of Avian Influenza Viruses Isolated From Marine Seal Colonies. Pathogens. 2024; 13(11):1009.  Abstract  
submitted by kickingbird at 5 days ago from Pathogens. 2024; 13(11):1009 (via https://www.mdpi.com/2076-0817/13/11/1009)
Genetically diverse avian influenza viruses (AIVs) are maintained in wild aquatic birds with increasingly frequent spillover into mammals, yet these represent a small proportion of the overall detections. ...

Thi Hao Vu, etc.,al. Unveiling the role of long non-coding RNAs in chicken immune response to highly pathogenic avian influenza H5N1 infection. Poultry Science.  Abstract  
submitted by kickingbird at 5 days ago from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
Avian influenza viruses (AIVs) pose a significant threat to global poultry production, necessitating effective control strategies to mitigate economic losses and ensure animal welfare. Long non-coding ...

Fuyin Bi, etc.,al. Epidemiological and Genetic Characterization of Human Infection with Avian Influenza AI H5N6 Virus in Guangxi, China, 2021. International Journal of Infectious Diseases.  Abstract  
submitted by kickingbird at 5 days ago from International Journal of Infectious Diseases (via https://www.sciencedirect.com/science/article/pii/S120197122)
Avian influenza (AI) H5N6 has replaced H5N1 as the predominant strain, and the increasing number of cases and complex recombination patterns pose significant threats to human health. The data were collected ...

Zhang Shuxia, Liu Jia, Tan Min, Yang Lei, Li Xiyan. Characteristics of Highly Pathogenic Avian Influenza A(H5) Clade 2.3.4.4b Viruses in China, 2010~2023. Disease Surveillance, 2024.  Abstract  
submitted by kickingbird at 7 days ago from Disease Surveillance, 2024 (via http://www.jbjc.org/)
Objectives Based on the global spread of highly pathogenic avian influenza A(H5) clade 2.3.4.4b viruses, this study analyzed the epidemic and phylogenetic evolution characteristics of clade 2.3.4.4b viruses ...

Zhou Y, Jin L, Lai X, Li Y, Sheng L, Xie G, Fang J. Adverse events associated with oseltamivir and baloxavir marboxil in against influenza virus therapy: A pharmacovigilance study using the FAERS database. PLoS One. 2024 Nov 13;19(11):e0308998.  Abstract  
submitted by kickingbird at 7 days ago from PLoS One. 2024 Nov 13;19(11):e0308998 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Background: Influenza virus is a widespread pathogen that poses significant health risks to humans. Oseltamivir and Baloxavir Marboxil are commonly utilized medications for both treating and preventing ...

Mostafa A, Naguib MM, Nogales A, Barre RS, Stewart. Avian influenza A (H5N1) virus in dairy cattle: origin, evolution, and cross-species transmission. mBio. 2024 Nov 13:e0254224.  Abstract  
submitted by kickingbird at 8 days ago from mBio. 2024 Nov 13:e0254224 (via https://journals.asm.org/doi/10.1128/mbio.02542-24)
Since the emergence of highly pathogenic avian influenza virus (HPAIV) H5N1 of clade 2.3.4.4b as a novel reassortant virus from subtype H5N8, the virus has led to a massive number of outbreaks worldwide ...

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