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2019-10-19 21:44:04
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Samir A, Adel A, Arafa A, Sultan H, Hussein Ahmed. Molecular pathogenic and host range determinants of reassortant Egyptian low pathogenic avian influenza H9N2 viruses from backyard chicken. Int J Vet Sci Med. 2019 Jul 11;7(1):10-19.  Abstract  
submitted by kickingbird at 10 hours ago from Int J Vet Sci Med. 2019 Jul 11;7(1):10-19 (via https://www.tandfonline.com/doi/full/10.1080/23144599.2019.1)
Since the introduction of H9N2 low pathogenic avian influenza virus in Egypt, it became an endemic disease causing considerable economic losses in different poultry sectors especially in the presence of ...

Venkatesan S, Nguyen-Van-Tam JS, Siebers PO. A novel framework for evaluating the impact of individual decision-making on public health outcomes and its potential application to study antiviral treatment collection during an influenza pandemic. PLoS One. 2019 Oct 17;14(10):e0223946.  Abstract  
submitted by kickingbird at 10 hours ago from PLoS One. 2019 Oct 17;14(10):e0223946 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
The importance of accounting for social and behavioural processes when studying public health emergencies has been well-recognised. For infectious disease outbreaks in particular, several methods of incorporating ...

Martinez L, et al. A Risk Classification Model to Predict Mortality Among Laboratory-Confirmed Avian Influenza A H7N9 Patients: A Population-Based Observational Cohort Study. J Infect Dis. 2019 Oct 17..  Abstract  
submitted by kickingbird at 10 hours ago from J Infect Dis. 2019 Oct 17. (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
BACKGROUND: Avian influenza A H7N9 (A/H7N9) is characterized by rapid progressive pneumonia and respiratory failure. Mortality among laboratory-confirmed cases is above 30%; however, the clinical course ...

Chan WM, et al. Development and evaluation of a conventional RT-PCR for differentiating emerging influenza B/Victoria lineage viruses with hemagglutinin amino acid deletion from B/Yamagata lineage viruses. J Med Virol. 2019 Oct 14.  Abstract  
submitted by kickingbird at 3 days ago from J Med Virol. 2019 Oct 14 (via https://onlinelibrary.wiley.com/doi/abs/10.1002/jmv.25607)
BACKGROUND: Recent influenza B/Victoria lineage viruses contain amino-acid deletions at positions 162-164 of the haemagglutinin (HA) protein. These amino acid deletions have affected the detection of B/Victoria ...

van Aalst R, et al. Comparative effectiveness of high dose versus adjuvanted influenza vaccine: A retrospective cohort study. Vaccine. 2019 Oct 9..  Abstract  
submitted by kickingbird at 5 days ago from Vaccine. 2019 Oct 9. (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
BACKGROUND: Adults 65?years and older (seniors) experience more complications following influenza infection than younger adults. We estimated the relative vaccine effectiveness (rVE) of a trivalent high ...

Moriyama M, Koshiba T, Ichinohe T. Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses. Nat Commun. 2019 Oct 11;10(1):4624..  Abstract  
submitted by kickingbird at 6 days ago from Nat Commun. 2019 Oct 11;10(1):4624. (via https://www.nature.com/articles/s41467-019-12632-5)
Cytosolic mitochondrial DNA (mtDNA) activates cGAS-mediated antiviral immune responses, but the mechanism by which RNA viruses stimulate mtDNA release remains unknown. Here we show that viroporin activity ...

Sobolev I, et al. Novel reassortant of H1N1 swine influenza virus detected in pig population in Russia. Emerg Microbes Infect. 2019;8(1):1456-1464.  Abstract  
submitted by kickingbird at 6 days ago from Emerg Microbes Infect. 2019;8(1):1456-1464 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1)
Pigs play an important role in interspecies transmission of the influenza virus, particularly as "mixing vessels" for reassortment. Two influenza A/H1N1 virus strains, A/swine/Siberia/1sw/2016 and A/swine/Siberia/4sw/2017, ...

An SH, et al. Novel Mutations Evading Avian Immunity around the Receptor Binding Site of the Clade 2.3.2.1c Hemagglutinin Gene Reduce Viral Thermostability and Mammalian Pathogenicity. Viruses. 2019 Oct 9;11(10)..  Abstract  
submitted by kickingbird at 6 days ago from Viruses. 2019 Oct 9;11(10). (via https://www.mdpi.com/1999-4915/11/10/923)
Abstract: Since 2007, highly pathogenic clade 2.3.2 H5N1 avian influenza A (A(H5N1)) viruses have evolved to clade 2.3.2.1a, b, and c; currently only 2.3.2.1c A(H5N1) viruses circulate in wild birds and ...

Usui T, et al. Outbreaks of highly pathogenic avian influenza in zoo birds caused by HA clade 2.3.4.4 H5N6 subtype viruses in Japan in winter 2016. Transbound Emerg Dis. 2019 Oct 11..  Abstract  
submitted by kickingbird at 6 days ago from Transbound Emerg Dis. 2019 Oct 11. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13386)
In late 2016, two zoos, one in northern Japan and the other in central Japan, experienced highly pathogenic avian influenza (HPAI) outbreaks, in which multiple zoo birds were infected with H5N6 subtype ...

Laporte M, et al. Hemagglutinin cleavability, acid-stability and temperature dependence optimize influenza B virus for replication in human airways. J Virol. 2019 Oct 9. pii: JVI.01430-19..  Abstract  
submitted by kickingbird at 7 days ago from J Virol. 2019 Oct 9. pii: JVI.01430-19. (via https://jvi.asm.org/content/early/2019/10/03/JVI.01430-19)
Influenza A virus (IAV) and influenza B virus (IBV) cause yearly epidemics with significant morbidity and mortality. When zoonotic IAVs enter the human population, the viral hemagglutinin (HA) requires ...

Hensen L, et al. Hemagglutinin-dependent tropism of H5N1 and H7N9 influenza viruses to human endothelial cells is determined by reduced stability of the HA which allows the virus to cope with inefficient endosomal aci. J Virol. 2019 Oct 9. pii: JVI.01223-19..  Abstract  
submitted by kickingbird at 7 days ago from J Virol. 2019 Oct 9. pii: JVI.01223-19. (via https://jvi.asm.org/content/early/2019/10/03/JVI.01223-19)
Previous studies revealed that certain avian influenza A viruses (IAVs), including zoonotic H5N1 and H7N9 IAVs, infect cultured human lung microvascular endothelial cells (HULEC) more efficiently than ...

Monteagudo PL, et al. Differential modulation of innate immune responses in human primary cells by influenza A viruses carrying human or avian non-structural 1 proteins. J Virol. 2019 Oct 9. pii: JVI.00999-19.  Abstract  
submitted by kickingbird at 7 days ago from J Virol. 2019 Oct 9. pii: JVI.00999-19 (via https://jvi.asm.org/content/early/2019/10/03/JVI.00999-19)
The influenza A virus (IAV) non-structural protein 1 (NS1) contributes to disease pathogenesis through the inhibition of host innate immune responses. Dendritic cells (DCs) release interferons (IFN), pro-inflammatory ...

Kong H, et al. Identification of key amino acids in the PB2 and M1 proteins of H7N9 influenza virus that affect its transmission in guinea pigs. J Virol. 2019 Oct 9.  Abstract  
submitted by kickingbird at 7 days ago from J Virol. 2019 Oct 9 (via https://jvi.asm.org/content/early/2019/10/03/JVI.01180-19)
Efficient human-to-human transmission is a prerequisite for a novel influenza virus to cause an influenza pandemic; however, the genetic determinants of influenza virus transmission are still not fully ...

Sautto GA, Ross TM. Hemagglutinin consensus-based prophylactic approaches to overcome influenza virus diversity. Vet Ital. 2019 Sep 30;55(3):195-201..  Abstract  
submitted by kickingbird at 7 days ago from Vet Ital. 2019 Sep 30;55(3):195-201. (via http://www.izs.it/vet_italiana/2019/55_3/VetIt_1944_10352_1.)
Each year millions of people are infected by influenza viruses, and this causes a substantial economic and health burden on our society. Influenza epidemics and pandemics are attributable to the ongoing ...

Kamiki H, et al. Adaptation of H3N2 canine influenza virus to feline cell culture. PLoS One. 2019 Oct 10;14(10):e0223507..  Abstract  
submitted by kickingbird at 7 days ago from PLoS One. 2019 Oct 10;14(10):e0223507. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
H3N2 canine influenza viruses are prevalent in Asian and North American countries. During circulation of the viruses in dogs, these viruses are occasionally transmitted to cats. If this canine virus causes ...

Nagant C, et al. Alteration of humoral, cellular and cytokine immune response to inactivated influenza vaccine in patients with Sickle Cell Disease. PLoS One. 2019 Oct 10;14(10):e0223991.  Abstract  
submitted by kickingbird at 7 days ago from PLoS One. 2019 Oct 10;14(10):e0223991 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
INTRODUCTION: Patients suffering from Sickle Cell Disease (SCD) are at increased risk for complications due to influenza virus. Annual influenza vaccination is strongly recommended but few clinical studies ...

Kode SS, Pawar SD, Tare DS, Keng SS, Mullick J. Amantadine resistance markers among low pathogenic avian influenza H9N2 viruses isolated from poultry in India, during 2009~2017. Microb Pathog. 2019 Oct 7:103779.  Abstract  
submitted by kickingbird at 7 days ago from Microb Pathog. 2019 Oct 7:103779 (via https://www.sciencedirect.com/science/article/pii/S088240101)
Antiviral susceptibility screening of avian influenza (AI) H9N2 viruses is crucial considering their role at the animal-human interface and potential to cause human infections. The Matrix 2 (M2) inhibitors ...

Fujimoto Y, Inoue H, Ozawa M, Matsuu A. Serological survey of influenza A virus infection in Japanese wild boars (Sus scrofa leucomystax). Microbiol Immunol. 2019 Oct 9..  Abstract  
submitted by kickingbird at 9 days ago from Microbiol Immunol. 2019 Oct 9. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/1348-0421.12)
We conducted a serological survey to detect antibodies against influenza A virus (IAV) in Japanese wild boars in Kagoshima prefecture, Japan, between 2014 and 2017. Sero-prevalence against a pandemic-like ...

Nishioka K, Daidoji T, Nakaya T. Demethylation around the transcriptional start site of the IFN-β gene induces IFN-β production and protection against influenza virus infection. Biochem Biophys Res Commun. 2019 Oct 5..  Abstract  
submitted by kickingbird at 9 days ago from Biochem Biophys Res Commun. 2019 Oct 5. (via https://www.sciencedirect.com/science/article/pii/S0006291X1)
Seasonal influenza is related to lifestyle-associated risk factors and it has been suggested that the epigenetic state of the individual plays an important role in the severity of infection. It is well ...

Fallah Mehrabadi MH, et al. Prevalence of Avian Influenza in Live Bird Markets, Bird Gardens, and Zoos in Iran in 2015: A Cross-sectional Study. Arch Razi Inst. 2019 Sep;74(3):243-250.  Abstract  
submitted by kickingbird at 9 days ago from Arch Razi Inst. 2019 Sep;74(3):243-250 (via http://archrazi.areeo.ac.ir/article_119274.html)
Avian Influenza (AI) H9N2 is endemic in Iran; therefore, it is necessary to estimate the disease prevalence among birds in live bird markets (LBMs) and assess the risk spread across the country. Accordingly, ...

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