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2019-2-17 0:46:46
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White MC1, Tao H, Steel J, Lowen AC. H5N8 and H7N9 packaging signals constrain HA reassortment with a seasonal H3N2 influenza A virus. Proc Natl Acad Sci U S A. 2019 Feb 13.  Abstract  
submitted by kickingbird at 3 hours ago from Proc Natl Acad Sci U S A. 2019 Feb 13 (via https://www.ncbi.nlm.nih.gov/pubmed/30760600)
Influenza A virus (IAV) has a segmented genome, which (i) allows for exchange of gene segments in coinfected cells, termed reassortment, and (ii) necessitates a selective packaging mechanism to ensure ...

Ito M, et al. Characterization of Mouse Monoclonal Antibodies Against the HA of A(H7N9) Influenza Virus. Viruses. 2019 Feb 11;11(2).  Abstract  
submitted by kickingbird at 3 hours ago from Viruses. 2019 Feb 11;11(2) (via https://www.ncbi.nlm.nih.gov/pubmed/30754701)
Many cases of human infection with the H7N9 virus have been detected in China since 2013. H7N9 viruses are maintained in chickens and are transmitted to humans at live bird markets. During circulation ...

Powell JD, et al. An avian influenza virus A(H7N9) reassortant that recently emerged in the United States with low pathogenic phenotype does not efficiently infect swine. Influenza Other Respir Viruses. 2019 Feb 13..  Abstract  
submitted by kickingbird at 3 hours ago from Influenza Other Respir Viruses. 2019 Feb 13. (via https://www.ncbi.nlm.nih.gov/pubmed/30761746)
In 2017, outbreaks of low and highly pathogenic avian H7N9 viruses were reported in four States in the United States. In total, over 270 000 birds died or were culled, causing significant economic loss. ...

McAuley JL, et al. Influenza Virus Neuraminidase Structure and Functions. Front Microbiol. 2019 Jan 29;10:39..  Abstract  
submitted by kickingbird at 3 hours ago from Front Microbiol. 2019 Jan 29;10:39. (via https://www.ncbi.nlm.nih.gov/pubmed/30761095)
With the constant threat of emergence of a novel influenza virus pandemic, there must be continued evaluation of the molecular mechanisms that contribute to virulence. Although the influenza A virus surface ...

Vrijens P, et al. Influenza virus entry via the GM3 ganglioside-mediated platelet-derived growth factor receptor β signalling pathway. J Gen Virol. 2019 Feb 14..  Abstract  
submitted by kickingbird at 3 hours ago from J Gen Virol. 2019 Feb 14. (via https://www.ncbi.nlm.nih.gov/pubmed/30762518)
The possible resistance of influenza virus against existing antiviral drugs calls for new therapeutic concepts. One appealing strategy is to inhibit virus entry, in particular at the stage of internalization. ...

Asha K, Kumar B. Emerging Influenza D Virus Threat: What We Know so Far!. J Clin Med. 2019 Feb 5;8(2)..  Abstract  
submitted by kickingbird at 3 hours ago from J Clin Med. 2019 Feb 5;8(2). (via https://www.ncbi.nlm.nih.gov/pubmed/30764577)
Influenza viruses, since time immemorial, have been the major respiratory pathogen known to infect a wide variety of animals, birds and reptiles with established lineages. They belong to the family Orthomyxoviridae ...

Havlickova M, et al. Circulation of influenza A and B in the Czech Republic from 2000-2001 to 2015-2016. BMC Infect Dis. 2019 Feb 14;19(1):160..  Abstract  
submitted by kickingbird at 3 hours ago from BMC Infect Dis. 2019 Feb 14;19(1):160. (via https://www.ncbi.nlm.nih.gov/pubmed/30764763)
BACKGROUND: To improve national influenza vaccination recommendations, additional data on influenza A and B virus circulation are needed. Here, we describe the circulation of influenza A and B in the Czech ...

Yang L, et al. Comparison of influenza disease burden in older populations of Hong Kong and Brisbane: the impact of influenza and pneumococcal vaccination. BMC Infect Dis. 2019 Feb 14;19(1):162..  Abstract  
submitted by kickingbird at 3 hours ago from BMC Infect Dis. 2019 Feb 14;19(1):162. (via https://www.ncbi.nlm.nih.gov/pubmed/30764779)
BACKGROUND: Influenza and pneumococcal vaccine uptake in the older population aged 65?years or over of Hong Kong dramatically increased since the 2003 SARS outbreak. This study is aimed to evaluate the ...

Kargarfard F, Sami A, Hemmatzadeh F, Ebrahimie E. Identifying mutation positions in all segments of influenza genome enables better differentiation between pandemic and seasonal strains. Gene. 2019 Feb 12. pii: S0378-1119(19)30058-7..  Abstract  
submitted by kickingbird at 3 hours ago from Gene. 2019 Feb 12. pii: S0378-1119(19)30058-7. (via https://www.ncbi.nlm.nih.gov/pubmed/30769139)
Influenza has a negative sense, single-stranded, segmented RNA. In the context of pandemic influenza research, most studies have focused on variations in the surface proteins (Hemagglutinin and Neuraminidase). ...

Alguacil-Ramos AM, et al. Rapid assessment of enhanced safety surveillance for influenza vaccine. Public Health. 2019 Feb 12;168:137-141.  Abstract  
submitted by kickingbird at 3 hours ago from Public Health. 2019 Feb 12;168:137-141 (via https://www.ncbi.nlm.nih.gov/pubmed/30769245)
OBJECTIVES: The enhanced safety surveillance for seasonal influenza vaccines established by the European Medicines Agency is required each season. Therefore, a registry capable of rapidly detecting and ...

Sugawara T, et al. Association of severe abnormal behavior and acetaminophen with/without neuraminidase inhibitors. J Infect Chemother. 2019 Feb 7.  Abstract  
submitted by kickingbird at 3 days ago from J Infect Chemother. 2019 Feb 7 (via https://www.ncbi.nlm.nih.gov/pubmed/30744989)
BACKGROUND: Even though abnormal behavior related with influenza and neuraminidase inhibitors (NI) has been discussed, the risks of acetaminophen and co-administration of NI and acetaminophen have not ...

Lytras T, Mouratidou E, Andreopoulou A,et al. Effect of early oseltamivir treatment on mortality in critically ill patients with different types of influenza: a multi-season cohort study. Clin Infect Dis. 2019 Feb 7.  Abstract  
submitted by kickingbird at 3 days ago from Clin Infect Dis. 2019 Feb 7 (via https://www.ncbi.nlm.nih.gov/pubmed/30753349)
Background: The available evidence on whether neuraminidase inhibitors reduce mortality in patients with influenza is inconclusive, and focuses solely on influenza A/H1N1pdm09. We assessed whether early ...

Nikolaev EV, Zloza A, Sontag ED. Immunobiochemical Reconstruction of Influenza Lung Infection-Melanoma Skin Cancer Interactions. Front Immunol. 2019 Jan 28;10:4.  Abstract  
submitted by kickingbird at 3 days ago from Front Immunol. 2019 Jan 28;10:4 (via https://www.ncbi.nlm.nih.gov/pubmed/30745900)
It was recently reported that acute influenza infection of the lung promoted distal melanoma growth in the dermis of mice. Melanoma-specific CD8+ T cells were shunted to the lung in the presence of the ...

Kwon JH, et al. Different pathogenicity of two strains of clade 2.3.4.4c H5N6 highly pathogenic avian influenza viruses bearing different PA and NS gene in domestic ducks. Virology. 2019 Jan 15;530:11-18.  Abstract  
submitted by kickingbird at 3 days ago from Virology. 2019 Jan 15;530:11-18 (via https://www.ncbi.nlm.nih.gov/pubmed/30753976)
H5Nx clade 2.3.4.4 highly pathogenic avian influenza viruses (HPAIVs) have been disseminated to wide geographic regions since 2014. In 2016, five distinct genotypes (C-1 to C-5) of clade 2.3.4.4c H5N6 ...

Zhao L,Zhang X,Wu Z,Huang K,Sun X,Chen H, Jin M. The Downregulation of MicroRNA hsa-miR-340-5p in IAV-Infected A549 Cells Suppresses Viral Replication by Targeting RIG-I and OAS2. Mol Ther Nucleic Acids. 2019 Jan 10;14:509-519..  Abstract  
submitted by kickingbird at 3 days ago from Mol Ther Nucleic Acids. 2019 Jan 10;14:509-519. (via https://www.ncbi.nlm.nih.gov/pubmed/30753994)
The influenza A virus poses serious public health challenges worldwide. Strikingly, small noncoding microRNAs (miRNAs) that modulate gene expression are closely involved in antiviral responses, although ...

Zheng Z, Lu Y, Short KR, Lu J. One health insights to prevent the next HxNy viral outbreak: learning from the epidemiology of H7N9. BMC Infect Dis. 2019 Feb 11;19(1):138.  Abstract  
submitted by kickingbird at 3 days ago from BMC Infect Dis. 2019 Feb 11;19(1):138 (via https://www.ncbi.nlm.nih.gov/pubmed/30744562)
BACKGROUND: With an increased incidence of viral zoonoses, there is an impetus to strengthen collaborations between public health, agricultural and environmental departments. This interdisciplinary cooperation, ...

Wan YH, et al. Genetic characteristic of hemagglutinin of avian influenza A (H7N9) virus in Guizhou Province in 2017. Zhonghua Yu Fang Yi Xue Za Zhi. 2019 Feb 6;53(2):2.  Abstract  
submitted by kickingbird at 3 days ago from Zhonghua Yu Fang Yi Xue Za Zhi. 2019 Feb 6;53(2):2 (via https://www.ncbi.nlm.nih.gov/pubmed/30744302)
The number of H7N9 bird flu cases was high and the situation was grim in guizhou province in 2017. To understand the molecular characteristics of the hemagglutinin gene (HA) and the risk of human infection ...

Leung VK, et al. Annual report on influenza viruses received and tested by the Melbourne WHO Collaborating Centre for Reference and Research on Influenza in 2016. Commun Dis Intell (2018). 2019 Feb 1;43..  Abstract  
submitted by kickingbird at 4 days ago from Commun Dis Intell (2018). 2019 Feb 1;43. (via https://www.ncbi.nlm.nih.gov/pubmed/30739429)
As part of its role in the World Health Organization’s (WHO) Global Influenza Surveillance and Response System (GISRS), the WHO Collaborating Centre for Reference and Research on Influenza in Melbourne ...

Bosco-Lauth AM, et al. Shedding of clade 2.3.4.4 H5N8 and H5N2 highly pathogenic avian influenza viruses in peridomestic wild birds in the U.S.. Transbound Emerg Dis. 2019 Feb 10.  Abstract  
submitted by kickingbird at 4 days ago from Transbound Emerg Dis. 2019 Feb 10 (via https://www.ncbi.nlm.nih.gov/pubmed/30740920)
European starlings (Sturnus vulgaris), house sparrows (Passer domesticus) and rock pigeons (Columba livia) are all wild birds commonly found in large numbers in and around human dwellings and domestic ...

Wang R, et al. Influenza M2 protein regulates MAVS-mediated signaling pathway through interacting with MAVS and increasing ROS production. Autophagy. 2019 Feb 11..  Abstract  
submitted by kickingbird at 4 days ago from Autophagy. 2019 Feb 11. (via https://www.ncbi.nlm.nih.gov/pubmed/30741586)
Influenza A virus can evade host innate immune response that is involved in several viral proteins with complicated mechanisms. To date, how influenza A M2 protein modulates the host innate immunity remains ...

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