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2019-1-19 23:27:59
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Bedford JG, O´Keeffe M, Reading PC, Wakim LM. Rapid interferon independent expression of IFITM3 following T cell activation protects cells from influenza virus infection. PLoS One. 2019 Jan 16;14(1):e0210132.  Abstract  
submitted by kickingbird at 1 days ago from PLoS One. 2019 Jan 16;14(1):e0210132 (via https://www.ncbi.nlm.nih.gov/pubmed/30650117)
Interferon-induced transmembrane protein 3 (IFITM3) is a potent antiviral protein that enhances cellular resistance to a variety of pathogens, including influenza virus. Classically defined as an interferon-stimulated ...

Liu L, Wang T, Wang M, Tong Q, Sun Y, Pu J, et al. Recombinant turkey herpesvirus expressing H9 hemagglutinin providing protection against H9N2 avian influenza. Virology. 2019 Jan 4;529:7-15.  Abstract  
submitted by kickingbird at 4 days ago from Virology. 2019 Jan 4;529:7-15 (via https://www.ncbi.nlm.nih.gov/pubmed/30641481)
H9N2 avian influenza viruses (AIVs) were prevailing in chickens, causing great economic losses and public health threats. In this study, turkey herpesviruses (HVT) was cloned as an infectious bacterial ...

Parra-Rojas C, Messling VV, Hernandez-Vargas EA. Adjuvanted influenza vaccine dynamics. Sci Rep. 2019 Jan 11;9(1):73.  Abstract  
submitted by kickingbird at 5 days ago from Sci Rep. 2019 Jan 11;9(1):73 (via https://www.ncbi.nlm.nih.gov/pubmed/30635599)
Adjuvanted influenza vaccines constitute a key element towards inducing neutralizing antibody responses in populations with reduced responsiveness, such as infants and elderly subjects, as well as in devising ...

Li J, et al. MOV10 sequesters the RNP of influenza A virus in the cytoplasm and is antagonized by viral NS1 protein. Biochem J. 2019 Jan 7.  Abstract  
submitted by kickingbird at 5 days ago from Biochem J. 2019 Jan 7 (via https://www.ncbi.nlm.nih.gov/pubmed/30617221)
MOV10 has emerged as an important host antiviral factor. MOV10 not only inhibits various viruses including human immunodeficiency virus type 1, hepatitis C virus and vesicular stomatitis virus, it also ...

Qin J, Peng O, Shen X, Gong L, Xue C, Cao Y. Multiple amino acid substitutions involved in the adaption of three avian-origin H7N9 influenza viruses in mice. Virol J. 2019 Jan 8;16(1):3.  Abstract  
submitted by kickingbird at 5 days ago from Virol J. 2019 Jan 8;16(1):3 (via https://www.ncbi.nlm.nih.gov/pubmed/30621708)
BACKGROUND: Avian influenza A H7N9 virus has caused five outbreak waves of human infections in China since 2013 and posed a dual challenge to public health and poultry industry. The number of reported ...

Qin C, Li W, Li Q, Yin W, Zhang X, et al. Real-time dissection of dynamic uncoating of individual influenza viruses. Proc Natl Acad Sci U S A. 2019 Jan 9..  Abstract  
submitted by kickingbird at 5 days ago from Proc Natl Acad Sci U S A. 2019 Jan 9. (via https://www.ncbi.nlm.nih.gov/pubmed/30626642)
Uncoating is an obligatory step in the virus life cycle that serves as an antiviral target. Unfortunately, it is challenging to study viral uncoating due to methodology limitations for detecting this transient ...

Lu FS, Hattab MW, Clemente CL, et al. Improved state-level influenza nowcasting in the United States leveraging Internet-based data and network approaches. Nat Commun. 2019 Jan 11;10(1):147.  Abstract  
submitted by kickingbird at 5 days ago from Nat Commun. 2019 Jan 11;10(1):147 (via https://www.ncbi.nlm.nih.gov/pubmed/30635558)
In the presence of health threats, precision public health approaches aim to provide targeted, timely, and population-specific interventions. Accurate surveillance methodologies that can estimate infectious ...

Evseev D, Magor KE. Innate Immune Responses to Avian Influenza Viruses in Ducks and Chickens. Vet Sci. 2019 Jan 10;6(1)..  Abstract  
submitted by kickingbird at 5 days ago from Vet Sci. 2019 Jan 10;6(1). (via https://www.ncbi.nlm.nih.gov/pubmed/30634569)
Mallard ducks are important natural hosts of low pathogenic avian influenza (LPAI) viruses and many strains circulate in this reservoir and cause little harm. Some strains can be transmitted to other hosts, ...

Lu C, Xing Y, Cai H, Shi Y, Liu J, Huang Y. Identification and analysis of long non-coding RNAs in response to H5N1 influenza viruses in duck (Anas platyrhynchos). BMC Genomics. 2019 Jan 11.  Abstract  
submitted by kickingbird at 5 days ago from BMC Genomics. 2019 Jan 11 (via https://www.ncbi.nlm.nih.gov/pubmed/30634898)
BACKGROUND: Long non-coding RNAs (lncRNAs) are important component of mammalian genomes, where their numbers are even larger than that of protein-coding genes. For example, human (Homo sapiens) (96,308 ...

Hao M, et al. The PA Subunit of the Influenza Virus Polymerase Complex Affects Replication and Airborne Transmission of the H9N2 Subtype Avian Influenza Virus. Viruses. 2019 Jan 9;11(1).  Abstract  
submitted by kickingbird at 5 days ago from Viruses. 2019 Jan 9;11(1) (via https://www.ncbi.nlm.nih.gov/pubmed/30634394)
The polymerase acidic (PA) protein is the third subunit of the influenza A virus polymerase. In recent years, studies have shown that PA plays an important role in overcoming the host species barrier and ...

Chastagner A, et al. Spatiotemporal Distribution and Evolution of the A/H1N1 2009 Pandemic Influenza Virus in Pigs in France from 2009 to 2017: Identification of a Potential Swine-Specific Lineage. J Virol. 2018 Nov 27;92(24).  Abstract  
submitted by kickingbird at 5 days ago from J Virol. 2018 Nov 27;92(24) (via https://www.ncbi.nlm.nih.gov/pubmed/30258006)
The H1N1 influenza virus responsible for the most recent pandemic in 2009 (H1N1pdm) has spread to swine populations worldwide while it replaced the previous seasonal H1N1 virus in humans. In France, surveillance ...

Souvestre M, Guinat C, Niqueux E, et al. Role of Backyard Flocks in Transmission Dynamics of Highly Pathogenic Avian Influenza A(H5N8) Clade 2.3.4.4, France, 2016-2017. Emerg Infect Dis. 2019 Mar 17;25(3).  Abstract  
submitted by kickingbird at 5 days ago from Emerg Infect Dis. 2019 Mar 17;25(3) (via https://www.ncbi.nlm.nih.gov/pubmed/30623754)
Highly pathogenic avian influenza A(H5N8) clade 2.3.4.4 spread in France during 2016-2017. We assessed the biosecurity and avian influenza virus infection status of 70 backyard flocks near H5N8-infected ...

Shkurupy VA, et al. Changes in the Structure of Mouse Kidney in the Acute Period after Infection with Influenza Viruses A/H5N1 and A/H1N1. Bull Exp Biol Med. 2019 Jan 9.  Abstract  
submitted by kickingbird at 5 days ago from Bull Exp Biol Med. 2019 Jan 9 (via https://www.ncbi.nlm.nih.gov/pubmed/30627911)
Changes in the kidney structure in outbred and inbred male BALB/c mice were analyzed in the acute period after infection with influenza viruses A/H5N1 (10 MLD50; 10 days) and A/H1N1 (1 MLD50; 30 days). ...

Zhuang J, Zang N, Ye C, Xu F. Lethal Avian Influenza A (H5N1) Virus Replicates in Pontomedullary Chemosensitive Neurons and Depresses Hypercapnic Ventilatory Response in Mice. Am J Physiol Lung Cell Mol Physiol. 2019 Jan 10.  Abstract  
submitted by kickingbird at 5 days ago from Am J Physiol Lung Cell Mol Physiol. 2019 Jan 10 (via https://www.ncbi.nlm.nih.gov/pubmed/30628490)
The highly pathogenic H5N1 (HK483) viral infection causes a depressed hypercapnic ventilatory response (dHCVR, 20%↓) at 2 days post-infection (dpi) and death at 7 dpi in mice, but the relevant mechanisms ...

Htwe KTZ, et al. Phylogeographic analysis of human influenza A and B viruses in Myanmar, 2010-2015. PLoS One. 2019 Jan 10;14(1):e0210550.  Abstract  
submitted by kickingbird at 5 days ago from PLoS One. 2019 Jan 10;14(1):e0210550 (via https://www.ncbi.nlm.nih.gov/pubmed/30629691)
We investigated the circulation patterns of human influenza A and B viruses in Myanmar between 2010 and 2015 by analyzing full HA genes. Upper respiratory tract specimens were collected from patients with ...

Martínez A, et al. Risk factors associated with severe outcomes in adult hospitalized patients according to influenza type and subtype. PLoS One. 2019 Jan 11;14(1):e0210353.  Abstract  
submitted by kickingbird at 5 days ago from PLoS One. 2019 Jan 11;14(1):e0210353 (via https://www.ncbi.nlm.nih.gov/pubmed/30633778)
Seasonal influenza is a cause of hospitalization, especially in people with underlying disease or extreme age, and its severity may differ depending on the types and subtypes of circulating viruses. We ...

Lomakina NF, et al. Three Mutations in the Stalk Region of Hemagglutinin Affect the pH of Fusion and Pathogenicity of H5N1 Influenza Virus. Mol Biol (Mosk). 2018 Nov-Dec;52(6):1029-1037.  Abstract  
submitted by kickingbird at 5 days ago from Mol Biol (Mosk). 2018 Nov-Dec;52(6):1029-1037 (via https://www.ncbi.nlm.nih.gov/pubmed/30633245)
Previously, an attenuated variant Ku/at was obtained from the highly pathogenic avian influenza virus A/chicken/Kurgan/3/2005 (H5N1) by a reverse selection method aimed at increasing the virus resistance ...

Gounder AP, Boon ACM. Influenza Pathogenesis: The Effect of Host Factors on Severity of Disease. J Immunol. 2019 Jan 15;202(2):341-350..  Abstract  
submitted by kickingbird at 10 days ago from J Immunol. 2019 Jan 15;202(2):341-350. (via https://www.ncbi.nlm.nih.gov/pubmed/30617115)
Influenza viruses continue to be a major global health threat. Severity and clinical outcome of influenza disease is determined by both viral and host factors. Viral factors have long been the subject ...

Lam JH, Baumgarth N. The Multifaceted B Cell Response to Influenza Virus. J Immunol. 2019 Jan 15;202(2):351-359.  Abstract  
submitted by kickingbird at 10 days ago from J Immunol. 2019 Jan 15;202(2):351-359 (via https://www.ncbi.nlm.nih.gov/pubmed/30617116)
Protection from yearly recurring, highly acute infections with a pathogen that rapidly and continuously evades previously induced protective neutralizing Abs, as seen during seasonal influenza virus infections, ...

Kuroki T, Osari S, Nagata K, Kawaguchi A. Influenza A Virus NS1 Protein Suppresses JNK1-Dependent Autophagosome Formation Mediated by Rab11a Recycling Endosomes. Front Microbiol. 2018 Dec 14;9:3120..  Abstract  
submitted by kickingbird at 10 days ago from Front Microbiol. 2018 Dec 14;9:3120. (via https://www.ncbi.nlm.nih.gov/pubmed/30619194)
Autophagy is an essential process for cellular metabolism and homeostasis, but also functions as one of innate immune responses against pathogen infection. However, in contrast to cellular metabolism and ...

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