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2022-8-12 4:51:32

Dai M, Sun H, Zhao L, Wu Q, You B, Xu F, Liao J, Z. Duck CD8 + T Cell Response to H5N1 Highly Pathogenic Avian Influenza Virus Infection In Vivo and In Vitro. J Immunol. 2022 Aug 8:ji2101147.  Abstract  
submitted by kickingbird at 2 days ago from J Immunol. 2022 Aug 8:ji2101147 (via https://pubmed.ncbi.nlm.nih.gov/35940633/)
Domestic ducks are the important host for H5N1 highly pathogenic avian influenza virus (HPAIV) infection and epidemiology, but little is known about the duck T cell response to H5N1 AIV infection. In infection ...

Cheng HY, Fung E, Choi KC, Zou HJ, Chair SY. Early risk of acute myocardial infarction following hospitalization for severe influenza infection in the middle-aged population of Hong Kong. PLoS One. 2022 Aug 9;17(8):e0272661.  Abstract  
submitted by kickingbird at 2 days ago from PLoS One. 2022 Aug 9;17(8):e0272661 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Introduction: Despite evidence suggesting an association between influenza infection and increased risk of acute myocardial infarction (AMI) in the older adult population (aged 65 years or above), little ...

Azeem S, Guo B, Sun D, Killian ML, Baroch JA, Yoon. Evaluation of PCR-Based Hemagglutinin Subtyping as a Tool to aid in Surveillance of Avian Influenza viruses in Migratory Wild Birds. J Virol Methods. 2022 Aug 2:114594.  Abstract  
submitted by kickingbird at 4 days ago from J Virol Methods. 2022 Aug 2:114594 (via https://www.sciencedirect.com/science/article/abs/pii/S01660)
The surveillance of migratory wild birds (MWBs) for avian influenza virus (AIV) allows detecting the emergence of highly pathogenic AIV that can infect domestic poultry and mammals, new subtypes, and antigenic/genetic ...

Wang T, Wei F, Jiang Z, Song J, Li C, Liu J. Influenza virus NS1 interacts with 14-3-3ε to antagonize the production of RIG-I-mediated type I interferons. Virology. 2022 Jul 20;574:47-56.  Abstract  
submitted by kickingbird at 6 days ago from Virology. 2022 Jul 20;574:47-56 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
For influenza A viruses (IAVs), non-structural protein 1 (NS1) protein was recognized to be the key factor to enhance virulence by antagonizing host innate anti-viral responses. However, for the pathways ...

He J, Huang H, Li B, Li H, Zhao Y, Li Y, Ye W, Qi. Identification of cytochrome c oxidase subunit 4 isoform 1 as a positive regulator of influenza virus replication. Front Microbiol. 2022 Jul 19;13:862205.  Abstract  
submitted by kickingbird at 6 days ago from Front Microbiol. 2022 Jul 19;13:862205 (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.8622)
Human infection with highly pathogenic H5N1 influenza virus causes severe respiratory diseases. Currently, the drugs against H5N1 are limited to virus-targeted inhibitors. However, drug resistance caused ...

Mao H, Cao L, Xu T, Xia X, Ren P, Han P, Li C, Hui. YWHAG inhibits influenza a virus replication by suppressing the release of viral M2 protein. Front Microbiol. 2022 Jul 19;13:951009.  Abstract  
submitted by kickingbird at 6 days ago from Front Microbiol. 2022 Jul 19;13:951009 (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.9510)
Influenza A virus (IAV) poses a serious threat to human life and property. The IAV matrix protein 2 (M2) is significant in viral budding. Increasing studies have proven the important roles of host factors ...

Oh J, Subbiah J, Kim KH, Park BR, Bhatnagar N, Gar. Impact of hemagglutination activity and M2e immunity on conferring protection against influenza viruses. Virology. 2022 Jul 16;574:37-46.  Abstract  
submitted by kickingbird at 7 days ago from Virology. 2022 Jul 16;574:37-46 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
To improve cross-protection of influenza vaccination, we tested conjugation of conserved M2e epitopes to the surface of inactivated influenza virus (iPR8-M2e*). Treatment of virus with chemical cross-linker ...

Chan M, Tiwary M, Wu HL, Tailor N, Vendramelli R,. Pandemic 1918 Influenza Virus Does Not Cause Lethal Infection in Rhesus or Cynomolgus Macaques. J Virol. 2022 Aug 4:e0072822.  Abstract  
submitted by kickingbird at 7 days ago from J Virol. 2022 Aug 4:e0072822 (via https://journals.asm.org/doi/10.1128/jvi.00728-22)
The 1918 H1N1 influenza pandemic was among the most severe in history, taking the lives of approximately 50 million people worldwide, and novel prophylactic vaccines are urgently needed to prevent another ...

Zhao X, Lin X, Li P, Chen Z, Zhang C, Manicassamy. Expanding the tolerance of segmented Influenza A Virus genome using a balance compensation strategy. PLoS Pathog. 2022 Aug 4;18(8):e1010756.  Abstract  
submitted by kickingbird at 7 days ago from PLoS Pathog. 2022 Aug 4;18(8):e1010756 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Reporter viruses provide powerful tools for both basic and applied virology studies, however, the creation and exploitation of reporter influenza A viruses (IAVs) have been hindered by the limited tolerance ...

Qiao Y, Zhang Y, Chen J, Jin S, Shan Y. A biepitope, adjuvant-free, self-assembled influenza nanovaccine provides cross-protection against H3N2 and H1N1 viruses in mice. Nano Res. 2022 Jul 1:1-11.  Abstract  
submitted by kickingbird at 7 days ago from Nano Res. 2022 Jul 1:1-11 (via https://link.springer.com/article/10.1007/s12274-022-4482-4)
Currently, the incorporation of multiple epitopes into vaccines is more desirable than the incorporation of a single antigen for universal influenza vaccine development. However, epitopes induce poor immune ...

Xie R, Adam DC, Edwards KM, Gurung S, Wei X, Cowli. Genomic epidemiology of seasonal influenza circulation in China during prolonged border closure from 2020 to 2021. Virus Evol. 2022 Jul 13;8(2):veac062.  Abstract  
submitted by kickingbird at 7 days ago from Virus Evol. 2022 Jul 13;8(2):veac062 (via https://academic.oup.com/ve/article/8/2/veac062/6643034)
China experienced a resurgence of seasonal influenza activity throughout 2021 despite intermittent control measures and prolonged international border closure. We show genomic evidence for multiple A(H3N2), ...

Yang F, Zhang X, Liu F, Yao H, Wu N, Wu H. Rapid emergence of a PB2 D701N substitution during adaptation of an H9N2 avian influenza virus in mice. Arch Virol. 2022 Aug 3.  Abstract  
submitted by kickingbird at 7 days ago from Arch Virol. 2022 Aug 3 (via https://link.springer.com/article/10.1007/s00705-022-05536-1)
H9N2 avian influenza viruses (AIVs) have been isolated frequently from multiple avian species and, occasionally, from humans. To explore the potential molecular basis of cross-species transmission of H9N2 ...

Wang S, Li Y, Zhang F, Jiang N, Zhuang Q, Hou G, J. Reverse transcription recombinase-aided amplification assay for H5 subtype avian influenza virus. Virol J. 2022 Jul 30;19(1):129.  Abstract  
submitted by kickingbird at 10 days ago from Virol J. 2022 Jul 30;19(1):129 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: The H5 subtype avian influenza virus (AIV) has caused huge economic losses to the poultry industry and is a threat to human health. A rapid and simple test is needed to confirm infection in ...

Reina J. The new generation of messenger RNA (mRNA) vaccines against influenza. Enferm Infecc Microbiol Clin (Engl Ed). 2022 Jul 2.  Abstract  
submitted by kickingbird at 12 days ago from Enferm Infecc Microbiol Clin (Engl Ed). 2022 Jul 2 (via https://www.sciencedirect.com/science/article/pii/S2529993X2)
Today there are multiple types of flu vaccines. The emergence of nucleic acid technology used in vaccines against SARS-CoV-2 suggests its future application against this infection. Against influenza, two ...

Liu Y, Jin W, Guan W, Zeng Z, Yang Z. The genetic characterization of hemagglutinin (HA), neuraminidase (NA) and polymerase acidic (PA) genes of H3N2 influenza viruses circulated in Guangdong Province of China during 2019-2020. Virus Genes. 2022 Jul 28.  Abstract  
submitted by kickingbird at 12 days ago from Virus Genes. 2022 Jul 28 (via https://pubmed.ncbi.nlm.nih.gov/35900664/)
The evolution of seasonal influenza viruses, which can cause virus antigenic drift to escape human herd immunity, is a significant public health problem. Here, we obtained hemagglutinin (HA), neuraminidase ...

Gass JD Jr, Kellogg HK, Hill NJ, Puryear WB, Nutte. Epidemiology and Ecology of Influenza A Viruses among Wildlife in the Arctic. Viruses. 2022 Jul 13;14(7):1531.  Abstract  
submitted by kickingbird at 15 days ago from Viruses. 2022 Jul 13;14(7):1531 (via https://www.mdpi.com/1999-4915/14/7/1531)
Arctic regions are ecologically significant for the environmental persistence and geographic dissemination of influenza A viruses (IAVs) by avian hosts and other wildlife species. Data describing the epidemiology ...

Chen G, Li H, Hao M, Li X, Dong Y, Zhang Y, Liu X,. Identification of Critical Genes and Pathways for Influenza A Virus Infections via Bioinformatics Analysis. Viruses. 2022 Jul 26;14(8):1625.  Abstract  
submitted by kickingbird at 15 days ago from Viruses. 2022 Jul 26;14(8):1625 (via https://pubmed.ncbi.nlm.nih.gov/35893690/)
Influenza A virus (IAV) requires the host cellular machinery for many aspects of its life cycle. Knowledge of these host cell requirements not only reveals molecular pathways exploited by the virus or ...

Fan S, Gu C, Kong H, Guan L, Neumann G, Kawaoka Y. Influenza Viruses Suitable for Studies in Syrian Hamsters. Viruses. 2022 Jul 26;14(8):1629.  Abstract  
submitted by kickingbird at 15 days ago from Viruses. 2022 Jul 26;14(8):1629 (via https://pubmed.ncbi.nlm.nih.gov/35893694/)
Several small animal models, including mice, Syrian hamsters, guinea pigs, and ferrets are used to study the pathogenicity, transmissibility, and antigenicity of seasonal and pandemic influenza viruses. ...

Gobbo F, Zanardello C, Bottinelli M, Budai J, Brun. Silent Infection of Highly Pathogenic Avian Influenza Virus (H5N1) Clade in a Commercial Chicken Broiler Flock in Italy. Viruses. 2022 Jul 22;14(8):1600.  Abstract  
submitted by kickingbird at 15 days ago from Viruses. 2022 Jul 22;14(8):1600 (via https://www.mdpi.com/1999-4915/14/8/1600)
From October 2021 to January 2022, different incursions of clade H5N1 HPAIV (Highly Pathogenic Avian Influenza Virus) occurred in several Italian regions with its main diffusion in Densely Poultry ...

Zhou Y, Gao W, Sun Y, Guo Y, Wu Y, Pu J. Effect of the Interaction between Viral PB2 and Host SphK1 on H9N2 AIV Replication in Mammals. Viruses. 2022 Jul 21;14(7):1585.  Abstract  
submitted by kickingbird at 15 days ago from Viruses. 2022 Jul 21;14(7):1585 (via https://www.mdpi.com/1999-4915/14/7/1585)
The H9N2 avian influenza virus (AIV) is currently widespread worldwide, posing a severe threat to the poultry industry and public health. Reassortment is an important way for influenza viruses to adapt ...

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