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2024-3-29 21:34:05
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Meng B, Wang Q, Leng H, Ren C, Feng C, Guo W, Feng. Evolutionary Events Promoted Polymerase Activity of H13N8 Avian Influenza Virus. Viruses. 2024 Feb 21;16(3):329.  Abstract  
submitted by kickingbird at 14 hours ago from Viruses. 2024 Feb 21;16(3):329 (via https://www.mdpi.com/1999-4915/16/3/329)
Wild birds are considered to be the natural reservoir hosts of avian influenza viruses (AIVs). Wild bird-origin AIVs may spill over into new hosts and overcome species barriers after evolutionary adaptation. ...

Lin S, Zhang Y, Yang J, Yang L, Li X, Bo H, Liu J,. Cross-Species Transmission Potential of H4 Avian Influenza Viruses in China: Epidemiological and Evolutionary Study. Viruses. 2024 Feb 24;16(3):353.  Abstract  
submitted by kickingbird at 14 hours ago from Viruses. 2024 Feb 24;16(3):353 (via https://www.mdpi.com/1999-4915/16/3/353)
H4 avian influenza viruses (AIVs) have been widely detected in live poultry markets in China. However, the potential public health impact of H4 AIVs remains largely uncertain. Here, we fully analyzed the ...

Tang S, Han B, Su C, Li H, Zhao S, Leng H, Feng Y,. Wild Bird-Origin H6N2 Influenza Virus Acquires Enhanced Pathogenicity after Single Passage in Mice. Viruses. 2024 Feb 25;16(3):357.  Abstract  
submitted by kickingbird at 14 hours ago from Viruses. 2024 Feb 25;16(3):357 (via https://www.mdpi.com/1999-4915/16/3/357)
The H6 subtype of avian influenza viruses (AIVs) has emerged as one of the predominant subtypes in both wild and domestic avian species. Currently, H6 AIVs have acquired the ability to infect a wide range ...

Mine J, Takadate Y, Kumagai A, Sakuma S, Tsunekuni. Genetics of H5N1 and H5N8 High-Pathogenicity Avian Influenza Viruses Isolated in Japan in Winter 2021-2022. Viruses. 2024 Feb 26;16(3):358.  Abstract  
submitted by kickingbird at 14 hours ago from Viruses. 2024 Feb 26;16(3):358 (via https://www.mdpi.com/1999-4915/16/3/358)
In winter 2021-2022, H5N1 and H5N8 high-pathogenicity avian influenza (HPAI) viruses (HPAIVs) caused serious outbreaks in Japan: 25 outbreaks of HPAI at poultry farms and 107 cases in wild birds or in ...

Gaymard A, Picard C, Vazzoler G, Massin P, Frobert. Impact of the H274Y Substitution on N1, N4, N5, and N8 Neuraminidase Enzymatic Properties and Expression in Reverse Genetic Influenza A Viruses. Viruses. 2024 Mar 1;16(3):388.  Abstract  
submitted by kickingbird at 15 hours ago from Viruses. 2024 Mar 1;16(3):388 (via https://www.mdpi.com/1999-4915/16/3/388)
The H274Y substitution (N2 numbering) in neuraminidase (NA) N1 confers oseltamivir resistance to A(H1N1) influenza viruses. This resistance has been associated with reduced N1 expression using transfected ...

Quignon E, Ferhadian D, Hache A, Vivet-Boudou V, I. Structural Impact of the Interaction of the Influenza A Virus Nucleoprotein with Genomic RNA Segments. Viruses. 2024 Mar 9;16(3):421.  Abstract  
submitted by kickingbird at 15 hours ago from Viruses. 2024 Mar 9;16(3):421 (via https://www.mdpi.com/1999-4915/16/3/421)
Influenza A viruses (IAVs) possess a segmented genome consisting of eight viral RNAs (vRNAs) associated with multiple copies of viral nucleoprotein (NP) and a viral polymerase complex. Despite the crucial ...

Allen JD, Ross TM. mRNA vaccines encoding computationally optimized hemagglutinin elicit protective antibodies against future antigenically drifted H1N1 and H3N2 influenza viruses isolated between 2018-2020. Front Immunol. 2024 Mar 12;15:1334670.  Abstract  
submitted by kickingbird at 2 days ago from Front Immunol. 2024 Mar 12;15:1334670 (via https://www.frontiersin.org/journals/immunology/articles/10.)
Background: The implementation of mRNA vaccines against COVID-19 has successfully validated the safety and efficacy of the platform, while at the same time revealing the potential for their applications ...

Jiang S, Li J, Cao J, Ou Y, Duan Y, Gan X. Clinical Characteristics of 118 Pediatric Patients With Acute Benign Myositis Associated With Influenza A Virus Infection. Pediatr Infect Dis J. 2024 Mar 27.  Abstract  
submitted by kickingbird at 2 days ago from Pediatr Infect Dis J. 2024 Mar 27 (via https://journals.lww.com/pidj/abstract/9900/clinical_charact)
Objective: The objective of this study was to investigate the clinical and laboratory features of acute benign myositis associated with influenza A virus infection in children.Methods: A retrospective ...

De Conto F. Avian Influenza A Viruses Modulate the Cellular Cytoskeleton during Infection of Mammalian Hosts. Pathogens. 2024 Mar 14;13(3):249.  Abstract  
submitted by kickingbird at 2 days ago from Pathogens. 2024 Mar 14;13(3):249 (via https://www.mdpi.com/2076-0817/13/3/249)
Influenza is one of the most prevalent causes of death worldwide. Influenza A viruses (IAVs) naturally infect various avian and mammalian hosts, causing seasonal epidemics and periodic pandemics with high ...

Kleij L, Bruder E, Raoux-Barbot D, Lejal N, Nevers. Genomic characterization of equine influenza A subtype H3N8 viruses by long read sequencing and functional analyses of the PB1-F2 virulence factor of A/equine/Paris/1/2018. Vet Res. 2024 Mar 22;55(1):36.  Abstract  
submitted by kickingbird at 5 days ago from Vet Res. 2024 Mar 22;55(1):36 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
Equine influenza virus (EIV) remains a threat to horses, despite the availability of vaccines. Strategies to monitor the virus and prevent potential vaccine failure revolve around serological assays, RT-qPCR ...

Bai Y, Lei H, Song W, Shin SC, Wang J, Xiao B, Ko?. Amino acids in the polymerase complex of shorebird-isolated H1N1 influenza virus impact replication and host-virus interactions in mammalian models. Emerg Microbes Infect. 2024 Mar 22:2332652.  Abstract  
submitted by kickingbird at 6 days ago from Emerg Microbes Infect. 2024 Mar 22:2332652 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
A diverse population of avian influenza A viruses (AIVs) are maintained in wild birds and ducks yet the zoonotic potential of AIVs in these environmental reservoirs and the host-virus interactions involved ...

Zhou Y, Li T, Zhang Y, Zhang N, Guo Y, Gao X, Peng. BAG6 inhibits influenza A virus replication by inducing viral polymerase subunit PB2 degradation and perturbing RdRp complex assembly. PLoS Pathog. 2024 Mar 18;20(3):e1012110.  Abstract  
submitted by kickingbird at 9 days ago from PLoS Pathog. 2024 Mar 18;20(3):e1012110 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The interaction between influenza A virus (IAV) and host proteins is an important process that greatly influences viral replication and pathogenicity. PB2 protein is a subunit of viral ribonucleoprotein ...

Song W, Zhao L, Liu S, Jia Y, Ma L, Liao M, Dai M. Analysis of H5N8 influenza virus infection in chicken with mApple reporter genes in vivo and in vitro. Vet Microbiol. 2024 Mar 11;292:110052.  Abstract  
submitted by kickingbird at 11 days ago from Vet Microbiol. 2024 Mar 11;292:110052 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
H5N8 highly pathogenic avian influenza virus (HPAIV) has caused huge losses to the global poultry industry and critically threatens public health. Chickens are the important host for the transmission. ...

Lagan P, Hamil M, Cull S, Hanrahan A, Wregor RM, L. Swine influenza A virus infection dynamics and evolution in intensive pig production systems. Virus Evol. 2024 Feb 27;10(1):veae017.  Abstract  
submitted by kickingbird at 14 days ago from Virus Evol. 2024 Feb 27;10(1):veae017 (via https://academic.oup.com/ve/article/10/1/veae017/7615508)
Swine influenza A virus (swIAV) is one of the main viral pathogens responsible for respiratory disease in farmed pigs. While outbreaks are often epidemic in nature, increasing reports suggest that continuous, ...

Kim HJ, Han CW, Jeong MS, Jang SB. Cryo-EM structure of Influenza A virus NS1 and antiviral protein kinase PKR complex. Biochem Biophys Res Commun. 2024 Mar 5;706:149728.  Abstract  
submitted by kickingbird at 14 days ago from Biochem Biophys Res Commun. 2024 Mar 5;706:149728 (via https://www.sciencedirect.com/science/article/abs/pii/S00062)
Influenza A virus is the cause of a widespread human disease with high morbidity and mortality rates. The influenza virus encodes non-structural protein 1 (NS1), an exceedingly multifunctional virulence ...

Arruda B, Baker ALV, Buckley A, Anderson TK, Torch. Divergent Pathogenesis and Transmission of Highly Pathogenic Avian Influenza A(H5N1) in Swine. Emerg Infect Dis. 2024 Mar 13;30(4).  Abstract  
submitted by kickingbird at 14 days ago from Emerg Infect Dis. 2024 Mar 13;30(4) (via https://pubmed.ncbi.nlm.nih.gov/38478379/)
Highly pathogenic avian influenza (HPAI) viruses have potential to cross species barriers and cause pandemics. Since 2022, HPAI A(H5N1) belonging to the goose/Guangdong 2.3.4.4b hemagglutinin phylogenetic ...

Heindl MR, Rupp A-L, Schwerdtner M, Bestle D, Harb. ACE2 acts as a novel regulator of TMPRSS2-catalyzed proteolytic activation of influenza A virus in airway cells. J Virol. 2024 Mar 12:e0010224.  Abstract  
submitted by kickingbird at Mar, 13, 2024 from J Virol. 2024 Mar 12:e0010224 (via https://journals.asm.org/doi/10.1128/jvi.00102-24)
The transmembrane serine protease 2 (TMPRSS2) activates the outer structural proteins of a number of respiratory viruses including influenza A virus (IAV), parainfluenza viruses, and various coronaviruses ...

Spruit CM, Palme DI, Li T, Ríos Carrasco M, Gabarr. Complex N-glycans are important for interspecies transmission of H7 influenza A viruses. J Virol. 2024 Mar 12:e0194123.  Abstract  
submitted by kickingbird at Mar, 13, 2024 from J Virol. 2024 Mar 12:e0194123 (via https://journals.asm.org/doi/10.1128/jvi.01941-23)
Influenza A viruses (IAVs) can overcome species barriers by adaptation of the receptor-binding site of the hemagglutinin (HA). To initiate infection, HAs bind to glycan receptors with terminal sialic acids, ...

Wen F, Yan Z, Chen G, Chen Y, Wang N, Li Z, Guo J,. Recent H9N2 avian influenza virus lost hemagglutination activity due to a K141N substitution in hemagglutinin. J Virol. 2024 Mar 11:e0024824.  Abstract  
submitted by kickingbird at Mar, 12, 2024 from J Virol. 2024 Mar 11:e0024824 (via https://journals.asm.org/doi/10.1128/jvi.00248-24)
The H9N2 avian influenza virus (AIV) represents a significant risk to both the poultry industry and public health. Our surveillance efforts in China have revealed a growing trend of recent H9N2 AIV strains ...

Kim JY, Jeong S, Kim DW, Lee DW, Lee DH, Kim D, Kw. Genomic epidemiology of highly pathogenic avian influenza A (H5N1) virus in wild birds in South Korea during 2021-2022: Changes in viral epidemic patterns. Virus Evol. 2024 Feb 7;10(1):veae014..  Abstract  
submitted by kickingbird at Mar, 10, 2024 from Virus Evol. 2024 Feb 7;10(1):veae014. (via https://academic.oup.com/ve/article/10/1/veae014/7606456)
Clade 2.3.4.4b highly pathogenic avian influenza A (HPAI) viruses have been detected in wild birds worldwide, causing recurrent outbreaks since 2016. During the winter of 2021-2022, we detected one H5N8 ...

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