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Farrukee R, etc.,al. CHARACTERIZATION OF INFLUENZA B VIRUS VARIANTS WITH REDUCED NEURAMINIDASE INHIBITOR SUSCEPTIBILITY. Antimicrob Agents Chemother. 2018 Sep 10..  Abstract  
submitted by kickingbird at Sep, 16, 2018 from Antimicrob Agents Chemother. 2018 Sep 10. (via https://www.ncbi.nlm.nih.gov/pubmed/30201817)
Treatment options for influenza B virus infections are limited to neuraminidase inhibitors (NAIs) which block the neuraminidase (NA) glycoprotein on the virion surface. The development of NAI resistance ...

Khrustalev VV, Khrustaleva TA, Kordyukova LV. Selection and structural analysis of the NY25 peptide - A vaccine candidate from hemagglutinin of swine-origin Influenza H1N1. Microb Pathog. 2018 Sep 7.  Abstract  
submitted by kickingbird at Sep, 16, 2018 from Microb Pathog. 2018 Sep 7 (via https://www.ncbi.nlm.nih.gov/pubmed/30201593)
The aim of this study was to construct a vaccine peptide candidate against pandemic Influenza H1N1 hemagglutinin and to test its structure. With the help of bioinformatic algorithms we showed that the ...

Xiao Y, Nolting JM, Sheng ZM, Bristol T, et al. Design and validation of a universal influenza virus enrichment probe set and its utility in deep sequence analysis of primary cloacal swab surveillance samples of wild birds. Virology 2018;524:182-191..  Abstract  
submitted by kickingbird at Sep, 16, 2018 from Virology 2018;524:182-191. (via https://www.ncbi.nlm.nih.gov/m/pubmed/30212665/)
Influenza virus infections in humans and animals are major public health concerns. In the current study, a set of universal influenza enrichment probes was developed to increase the sensitivity of sequence-based ...

Yang C, Liu X, Gao Q, Cheng T, et al.. The nucleolar protein LYAR facilitates ribonucleoprotein assembly of influenza A virus. J Virol 2018 Sep 12.  Abstract  
submitted by kickingbird at Sep, 16, 2018 from J Virol 2018 Sep 12 (via https://www.ncbi.nlm.nih.gov/m/pubmed/30209172/)
Influenza A viral ribonucleoprotein (vRNP) is responsible for transcription and replication of the viral genome in infected cells and depend on host factors for its functions. Identification of the host ...

Keeler SP, Agapov EV, Hinojosa ME, Letvin AN, et a. Influenza A Virus Infection Causes Chronic Lung Disease Linked to Sites of Active Viral RNA Remnants. J Immunol 2018 Sep 12..  Abstract  
submitted by kickingbird at Sep, 16, 2018 from J Immunol 2018 Sep 12. (via https://www.ncbi.nlm.nih.gov/m/pubmed/30209189/)
Clinical and experimental observations suggest that chronic lung disease is linked to respiratory viral infection. However, the long-term aspect of this relationship is not yet defined using a virus that ...

Jesper J. Madsen, John M. A. Grime, Jeremy S. Ross. Entropic forces drive clustering and spatial localization of influenza A M2 during viral budding. PNAS September 11, 2018 115 (37) E8595-E8603.  Abstract  
submitted by kickingbird at Sep, 14, 2018 from PNAS September 11, 2018 115 (37) E8595-E8603 (via http://www.pnas.org/content/115/37/E8595)
The influenza A matrix 2 (M2) transmembrane protein facilitates virion release from the infected host cell. In particular, M2 plays a role in the induction of membrane curvature and/or in the scission ...

Levene RE, Gaglia MM. Host Shutoff in Influenza A Virus: Many Means to an End. Viruses. 2018 Sep 5;10(9)..  Abstract  
submitted by kickingbird at Sep, 13, 2018 from Viruses. 2018 Sep 5;10(9). (via https://www.ncbi.nlm.nih.gov/pubmed/30189604)
Influenza A virus carries few of its own proteins, but uses them effectively to take control of the infected cells and avoid immune responses. Over the years, host shutoff, the widespread down-regulation ...

Ryan KA, etc.,al. Cellular immune response to human influenza viruses differs between H1N1 and H3N2 subtypes in the ferret lung. PLoS One. 2018 Sep 7;13(9):e0202675..  Abstract  
submitted by kickingbird at Sep, 13, 2018 from PLoS One. 2018 Sep 7;13(9):e0202675. (via https://www.ncbi.nlm.nih.gov/pubmed/30192789)
Seasonal influenza virus infections cause yearly epidemics which are the source of a significant public health burden worldwide. The ferret model for human influenza A virus (IAV) is widely used and has ...

Loughran ST, etc.,al. Influenza infection directly alters innate IL-23 and IL-12p70 and subsequent IL-17A and IFN-γ responses to pneumococcus in vitro in human monocytes. PLoS One. 2018 Sep 7;13(9):e0203521.  Abstract  
submitted by kickingbird at Sep, 13, 2018 from PLoS One. 2018 Sep 7;13(9):e0203521 (via https://www.ncbi.nlm.nih.gov/pubmed/30192848)
Influenza virus is highly contagious and poses substantial public health problems due to its strong association with morbidity and mortality. Approximately 250,000-500,000 deaths are caused by seasonal ...

Bolduc M, etc.,al. The quest for a nanoparticle-based vaccine inducing broad protection to influenza viruses. Nanomedicine. 2018 Sep 4.  Abstract  
submitted by kickingbird at Sep, 13, 2018 from Nanomedicine. 2018 Sep 4 (via https://www.ncbi.nlm.nih.gov/pubmed/30193813)
Influenza virus infections are a significant public threat and the best approach to prevent them is through vaccination. Because of the perpetual changes of circulating influenza strains, the efficacy ...

Cheon SH, etc.,al. Genetic evidence for the intercontinental movement of avian influenza viruses possessing North American-origin nonstructural gene allele B into South Korea. Infect Genet Evol. 2018 Sep.  Abstract  
submitted by kickingbird at Sep, 13, 2018 from Infect Genet Evol. 2018 Sep (via https://www.ncbi.nlm.nih.gov/pubmed/30196122)
Avian influenza viruses (AIVs) are genetically separated by geographical barriers, resulting in the independent evolution of North American and Eurasian lineages. In the present study, to determine whether ...

Sun Y, Liu Z, Liu D, Chen J, Gan F. Low-Level Aflatoxin B1 Promotes Influenza Infection and Modulates a Switch in Macrophage Polarization from M1 to M2. Cell Physiol Biochem. 2018 Sep 7;49(3):1110-1126..  Abstract  
submitted by kickingbird at Sep, 13, 2018 from Cell Physiol Biochem. 2018 Sep 7;49(3):1110-1126. (via https://www.ncbi.nlm.nih.gov/pubmed/30196302)
BACKGROUND/AIMS: Swine influenza virus (SIV) is a major pathogen of both animals and humans. Afatoxin B1 (AFB1) is one of the most common mycotoxins in feed and food. However, the central contribution ...

Kim KH, etc.,al. Virus-like particles presenting flagellin exhibit unique adjuvant effects on eliciting T helper type 1 humoral and cellular immune responses to poor immunogenic influenza virus M2e protein vaccine. Virology. 2018 Sep 7;524:172-181..  Abstract  
submitted by kickingbird at Sep, 13, 2018 from Virology. 2018 Sep 7;524:172-181. (via https://www.ncbi.nlm.nih.gov/pubmed/30199754)
Current licensed adjuvants including aluminum hydroxide (alum) bias immune responses toward T helper type 2 (Th2) immune responses. We tested whether virus-like particles presenting flagellin (Flag VLP) ...

Bui VN, etc.,al. Bioaerosol Sampling to Detect Avian Influenza Virus in Hanoi´s Largest Live Poultry Market. Clin Infect Dis. 2018 Aug 31.  Abstract  
submitted by kickingbird at Sep, 9, 2018 from Clin Infect Dis. 2018 Aug 31 (via https://www.ncbi.nlm.nih.gov/pubmed/30184114)
Background: Newly emergent and virulent strains of H7N9 avian influenza virus are rapidly spreading in China and threaten to invade Vietnam. We sought to introduce aerosol sampling for avian influenza ...

Yitbarek A, etc.,al. Gut microbiota-mediated protection against influenza virus subtype H9N2 in chickens is associated with modulation of the innate responses. Sci Rep. 2018 Sep 4;8(1):13189..  Abstract  
submitted by kickingbird at Sep, 9, 2018 from Sci Rep. 2018 Sep 4;8(1):13189. (via https://www.ncbi.nlm.nih.gov/pubmed/30181578)
Commensal gut microbiota plays an important role in health and disease. The current study was designed to assess the role of gut microbiota of chickens in the initiation of antiviral responses against ...

Sjaastad LE, etc.,al. Distinct antiviral signatures revealed by the magnitude and round of influenza virus replication in vivo. Proc Natl Acad Sci U S A. 2018 Sep 4..  Abstract  
submitted by kickingbird at Sep, 9, 2018 from Proc Natl Acad Sci U S A. 2018 Sep 4. (via https://www.ncbi.nlm.nih.gov/pubmed/30181264)
Influenza virus has a broad cellular tropism in the respiratory tract. Infected epithelial cells sense the infection and initiate an antiviral response. To define the antiviral response at the earliest ...

Sigal D, Reid JNS, Wahl LM. Effects of Transmission Bottlenecks on the Diversity of Influenza A Virus. Genetics. 2018 Sep 4. pii: genetics.301510.2018.  Abstract  
submitted by kickingbird at Sep, 9, 2018 from Genetics. 2018 Sep 4. pii: genetics.301510.2018 (via https://www.ncbi.nlm.nih.gov/pubmed/30181193)
We investigate the fate of de novo mutations that occur during the in-host replication of a pathogenic virus, predicting the probability that such mutations are passed on during disease transmission to ...

Gun L, Haixian P, Yumiao R, Han T, Jingqi L. Codon usage characteristics of PB2 gene in influenza A H7N9 virus from different host species. Infect Genet Evol. 2018 Sep 1..  Abstract  
submitted by kickingbird at Sep, 6, 2018 from Infect Genet Evol. 2018 Sep 1. (via https://www.ncbi.nlm.nih.gov/pubmed/30179716)
The influenza A H7N9 virus is a highly contagious virus which can only infect poultry before early 2013. But after that time, it widely caused human infections in China and brought Southeast Asia great ...

Phan HT, Gresch U, Conrad U. In vitro-Formulated Oligomers of Strep-Tagged Avian Influenza Haemagglutinin Produced in Plants Cause Neutralizing Immune Responses. Front Bioeng Biotechnol. 2018 Aug 20;6:115..  Abstract  
submitted by kickingbird at Sep, 6, 2018 from Front Bioeng Biotechnol. 2018 Aug 20;6:115. (via https://www.ncbi.nlm.nih.gov/pubmed/30177967)
The worldwide emergence of the novel influenza A H5N1 and H5N8 has notably and directly impacted the poultry industry, resulting in the need for effective and cheap vaccination strategies to protect poultry ...

Zhao N, etc.,al. Influenza virus infection causes global RNAPII termination defects. Nat Struct Mol Biol. 2018 Sep 3.  Abstract  
submitted by kickingbird at Sep, 6, 2018 from Nat Struct Mol Biol. 2018 Sep 3 (via https://www.ncbi.nlm.nih.gov/pubmed/30177761)
Viral infection perturbs host cells and can be used to uncover regulatory mechanisms controlling cellular responses and susceptibility to infections. Using cell biological, biochemical, and genetic tools, ...

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