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2024-11-26 12:45:18
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Hirotsu N, Saisho Y, Hasegawa T. The effect of neuraminidase inhibitors on household transmission in Japanese patients with influenza A and B infection: a prospective, observational study. Influenza Other Respir Viruses. 2018 Jul 10.  Abstract  
submitted by kickingbird at Jul, 16, 2018 from Influenza Other Respir Viruses. 2018 Jul 10 (via https://www.ncbi.nlm.nih.gov/pubmed/29989680)
BACKGROUND: The relative ability of neuraminidase inhibitors (NAIs) to reduce household influenza transmission when given to index patients is not established.OBJECTIVES: To compare daily secondary infection ...

Schr?der T. etc.,al. The clinically approved MEK inhibitor Trametinib efficiently blocks influenza A virus propagation and cytokine expression. Antiviral Res. 2018 Jul 7;157:80-92.  Abstract  
submitted by kickingbird at Jul, 16, 2018 from Antiviral Res. 2018 Jul 7;157:80-92 (via https://www.ncbi.nlm.nih.gov/pubmed/29990517)
Influenza A virus (IAV) infections are still a major global threat for humans, especially for the risk groups of young children and the elderly. Annual epidemics and sporadically occurring pandemics highlight ...

He Z, Tao H. Epidemiology and ARIMA Model of Positive-Rate of Influenza Viruses among Children in Wuhan, China: A Nine-Year Retrospective Study. Int J Infect Dis. 2018 Jul 7. pii: S1201-9712(18)3.  Abstract  
submitted by kickingbird at Jul, 16, 2018 from Int J Infect Dis. 2018 Jul 7. pii: S1201-9712(18)3 (via https://www.ncbi.nlm.nih.gov/pubmed/29990540)
OBJECTIVE: Influenza is a common childhood disease and protecting children by predicting the positive rate of influenza virus is important as vaccines are not routinely administered in China. Our study ...

Yip JLY, etc.,al. Outbreaks of influenza-like illness in care homes in the East of England: impact of variations in neuraminidase inhibitor provision. Public Health. 2018 Jul 7;162:98-103..  Abstract  
submitted by kickingbird at Jul, 16, 2018 from Public Health. 2018 Jul 7;162:98-103. (via https://www.ncbi.nlm.nih.gov/pubmed/29990618)
OBJECTIVES: To examine the differences in outcomes related to variable provision of antivirals in care home respiratory outbreaks.STUDY DESIGN: This is a retrospective observational study.METHODS: Routinely ...

Lau SY, etc.,al. tification of meteorological factors associated with human infection with avian influenza A H7N9 virus in Zhejiang Province, China. Sci Total Environ. 2018 Jul 6;644:696-709.  Abstract  
submitted by kickingbird at Jul, 16, 2018 from Sci Total Environ. 2018 Jul 6;644:696-709 (via https://www.ncbi.nlm.nih.gov/pubmed/29990917)
BACKGROUND: Since the first reported human infection with an avian-origin influenza A (H7N9) virus in China in early 2013, there have been recurrent outbreaks of the virus in the country. Previous studies ...

Bangaru S, etc.,al. A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nat Commun. 2018 Jul 10;9(1):2669.  Abstract  
submitted by kickingbird at Jul, 16, 2018 from Nat Commun. 2018 Jul 10;9(1):2669 (via https://www.ncbi.nlm.nih.gov/pubmed/29991715)
The high rate of antigenic drift in seasonal influenza viruses necessitates frequent changes in vaccine composition. Recent seasonal H3 vaccines do not protect against swine-origin H3N2 variant (H3N2v) ...

Sean G. Young,Andrew Kitchen, Ghazi Kayali,Margare. Unlocking pandemic potential: prevalence and spatial patterns of key substitutions in avian influenza H5N1 in Egyptian isolates. BMC Infectious Diseases201818:314.  Abstract  
submitted by kickingbird at Jul, 10, 2018 from BMC Infectious Diseases201818:314 (via https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128)
BackgroundAvian influenza H5N1 has a high human case fatality rate, but is not yet well-adapted to human hosts. Amino acid substitutions currently circulating in avian populations may enhance viral fitness ...

Gao Z, etc.,al. The PA-interacting host protein nucleolin acts as an antiviral factor during highly pathogenic H5N1 avian influenza virus infection. Arch Virol. 2018 Jul 5.  Abstract  
submitted by kickingbird at Jul, 9, 2018 from Arch Virol. 2018 Jul 5 (via https://www.ncbi.nlm.nih.gov/pubmed/29974255)
Polymerase acidic (PA) protein is a multifunctional regulator of influenza A virus (IAV) replication and pathogenesis. In a previous study, we reported that nucleolin (NCL) is a novel PA-interacting host ...

Keating R, Morris MY, etc.,al. Potential killers exposed: tracking endogenous influenza-specific CD8+ T cells. Immunol Cell Biol. 2018 Jul 4..  Abstract  
submitted by kickingbird at Jul, 9, 2018 from Immunol Cell Biol. 2018 Jul 4. (via https://www.ncbi.nlm.nih.gov/pubmed/29972699)
Current influenza A virus (IAV) vaccines stimulate antibody responses that are directed against variable regions of the virus, and are therefore ineffective against divergent strains. As CD8+ T cells target ...

Lawrence JL, Hindi H. Capillary Leak Syndrome Aggravated by Influenza Type A Infection. Cureus. 2018 Apr 30;10(4):e2554..  Abstract  
submitted by kickingbird at Jul, 9, 2018 from Cureus. 2018 Apr 30;10(4):e2554. (via https://www.ncbi.nlm.nih.gov/pubmed/29974010)
A 41-year-old female presented to the emergency department with nausea, vomiting, and diarrhea. Five days prior to this, she tested positive for influenza type A in an urgent care clinic and received Tamiflu. ...

Jaramillo JM, Ma J, van den Driessche P, Yuan S. Host contact structure is important for the recurrence of Influenza A. J Math Biol. 2018 Jul 4.  Abstract  
submitted by kickingbird at Jul, 9, 2018 from J Math Biol. 2018 Jul 4 (via https://www.ncbi.nlm.nih.gov/pubmed/29974201)
An important characteristic of influenza A is its ability to escape host immunity through antigenic drift. A novel influenza A strain that causes a pandemic confers full immunity to infected individuals. ...

Hu J, Ma C, Liu X. PA-X: a key regulator of influenza A virus pathogenicity and host immune responses. Med Microbiol Immunol. 2018 Jul 4..  Abstract  
submitted by kickingbird at Jul, 9, 2018 from Med Microbiol Immunol. 2018 Jul 4. (via https://www.ncbi.nlm.nih.gov/pubmed/29974232)
PA-X, a fusion protein belonging to influenza A viruses (IAVs), integrating the N-terminal 191 amino acids of PA gene and the ribosomal frame-shifting product that lengthens out to 41 or 61 amino acids. ...

Haruki A, etc.,al. Spontaneous remission of adult-onset minimal change nephrotic syndrome associated with influenza B infection: a case report. BMC Nephrol. 2018 Jul 4;19(1):162..  Abstract  
submitted by kickingbird at Jul, 9, 2018 from BMC Nephrol. 2018 Jul 4;19(1):162. (via https://www.ncbi.nlm.nih.gov/pubmed/29973143)
BACKGROUND: While the majority of adult-onset minimal change nephrotic syndrome (MCNS) is a primary or an idiopathic form of disease, it can also occur as a secondary form. Reports on the spontaneous remission ...

Thulin NK, Wang TT. The Role of Fc Gamma Receptors in Broad Protection against Influenza Viruses. Vaccines (Basel). 2018 Jun 29;6(3).  Abstract  
submitted by kickingbird at Jul, 9, 2018 from Vaccines (Basel). 2018 Jun 29;6(3) (via https://www.ncbi.nlm.nih.gov/pubmed/29966222)
Recent studies have revealed multiple roles for Fc gamma receptors (FcγRs) in broad immunity against influenza viruses. Activating FcγR pathways can be harnessed to confer protection mediated ...

Qiang X, Kou Z, Fang G, Wang Y. Scoring Amino Acid Mutations to Predict Avian-to-Human Transmission of Avian Influenza Viruses. Molecules. 2018 Jun 29;23(7).  Abstract  
submitted by kickingbird at Jul, 9, 2018 from Molecules. 2018 Jun 29;23(7) (via https://www.ncbi.nlm.nih.gov/pubmed/29966263)
Avian influenza virus (AIV) can directly cross species barriers and infect humans with high fatality. Using machine learning methods, the present paper scores the amino acid mutations and predicts interspecies ...

Baudon E,etc.,al. Swine influenza viruses in Northern Vietnam in 2013~2014. Emerg Microbes Infect. 2018 Jul 2;7(1):123.  Abstract  
submitted by kickingbird at Jul, 9, 2018 from Emerg Microbes Infect. 2018 Jul 2;7(1):123 (via https://www.ncbi.nlm.nih.gov/pubmed/29967457)
Swine are an important intermediate host for emergence of pandemic influenza. Vietnam is the largest swine producer in South East Asia. Systematic virological and serological surveillance of swine influenza ...

Liang F, etc.,al. Forecasting influenza epidemics by integrating internet search queries and traditional surveillance data with the support vector machine regression model in Liaoning, from 2011 to 2015. PeerJ. 2018 Jun 25;6:e5134..  Abstract  
submitted by kickingbird at Jul, 9, 2018 from PeerJ. 2018 Jun 25;6:e5134. (via https://www.ncbi.nlm.nih.gov/pubmed/29967755)
Background: Influenza epidemics pose significant social and economic challenges in China. Internet search query data have been identified as a valuable source for the detection of emerging influenza epidemics. ...

Zhu R, etc.,al. Genetic and biological characterization of H9N2 avian influenza viruses isolated in China from 2011 to 2014.. PLoS One. 2018 Jul 3;13(7):e0199260..  Abstract  
submitted by kickingbird at Jul, 9, 2018 from PLoS One. 2018 Jul 3;13(7):e0199260. (via https://www.ncbi.nlm.nih.gov/pubmed/29969454)
The genotypes of the H9N2 avian influenza viruses have changed since 2013 when almost all H9N2 viruses circulating in chickens in China were genotype 57 (G57) with the fittest lineage of each gene. To ...

Smith BL, etc.,al. Avian Influenza Virus PB1 Gene in H3N2 Viruses Evolved in Humans To Reduce Interferon Inhibition by Skewing Codon Usage toward Interferon-Altered tRNA Pools. MBio. 2018 Jul 3;9(4)..  Abstract  
submitted by kickingbird at Jul, 9, 2018 from MBio. 2018 Jul 3;9(4). (via https://www.ncbi.nlm.nih.gov/pubmed/29970470)
Influenza A viruses cause an annual contagious respiratory disease in humans and are responsible for periodic high-mortality human pandemics. Pandemic influenza A viruses usually result from the reassortment ...

Obul M, etc.,al. Structural modification on rupestonic acid leads to highly potent inhibitors against influenza virus. Mol Divers. 2018 Jul 3..  Abstract  
submitted by kickingbird at Jul, 9, 2018 from Mol Divers. 2018 Jul 3. (via https://www.ncbi.nlm.nih.gov/pubmed/29971616)
Influenza viruses are responsible for seasonal epidemics and occasional pandemics, which cause significant morbidity and mortality. Although several drugs (adamantanes and neuraminidase inhibitors) are ...

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