Hara K, Kashiwagi T, Hamada N, Watanabe H, et al. Basic amino acids in the N-terminal half of the PB2 subunit of influenza virus RNA polymerase are involved in both transcription and replication. J Gen Virol 2017 May 22.. Abstract
submitted by kickingbird at May, 29, 2017 from J Gen Virol 2017 May 22. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28530165/)
The PB2 subunit of influenza virus RNA polymerase is known to be involved in the initiation of transcription of the virus genome via cap binding. However, other specific roles of PB2 for viral RNA synthesis ... Lone NA, Spackman E, Kapczynski D. Immunologic evaluation of 10 different adjuvants for use in vaccines for chickens against highly pathogenic avian influenza virus. Vaccine 2017 May 13. Abstract
submitted by kickingbird at May, 22, 2017 from Vaccine 2017 May 13 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28511853/)
Avian influenza viruses (AIV) are a threat to poultry production worldwide. Vaccination is utilized as a component of control programs for both high pathogenicity (HP) and low pathogenicity (LP) AIV. Over ... Zhao D, Liang L, Wang S, Nakao T, et al. Glycosylation of the Hemagglutinin Protein of H5N1 Influenza Virus Increases Its Virulence in Mice by Exacerbating the Host Immune Response. J Virol 2017;91. Abstract
submitted by kickingbird at May, 22, 2017 from J Virol 2017;91 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28100622/)
The highly pathogenic avian influenza (HPAI) H5N1 viruses continue to circulate in nature and threaten public health. Although several viral determinants and host factors that influence the virulence of ... Pereira CF, Read EKC, Wise HM, Amorim MJ, et al. The influenza A virus NS1 protein promotes efficient nuclear export of unspliced viral M1 mRNA. Virol 2017 May 17. pii: JVI.00528-17. Abstract
submitted by kickingbird at May, 22, 2017 from Virol 2017 May 17. pii: JVI.00528-17 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28515301/)
Influenza A virus mRNAs are transcribed by the viral RNA-dependent RNA polymerase in the cell nucleus before being exported to the cytoplasm for translation. Segment 7 produces two major transcripts: an ... Lee N, Cao B, Ke C, Lu H, et al. IFITM3, TLR3, and CD55 Genes SNPs and Cumulative Ge-netic Risks for Severe Outcomes in Chinese Patients with H7N9 / H1N1pdm09 Influenza. J Infect Dis 2017 May 16. Abstract
submitted by kickingbird at May, 22, 2017 from J Infect Dis 2017 May 16 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28510725/)
Background: We examined associations between SNPs (single-nucleotide-polymorphisms) of IFITM3, TLR3, and CD55 genes and influenza clinical outcomes in Chinese patients. Methods: A multicenter-study was ... Spreco A, Eriksson O, Dahlstrom O, Timpka T, et al. Influenza detection and prediction algorithms: comparative accuracy trial in ?sterg?tland county, Sweden, 2008-2012. Epidemiol Infect 2017 May 17. Abstract
submitted by kickingbird at May, 22, 2017 from Epidemiol Infect 2017 May 17 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28511741/)
Methods for the detection of influenza epidemics and prediction of their progress have seldom been comparatively evaluated using prospective designs. This study aimed to perform a prospective comparative ... Root JJ, Shriner SA, Ellis JW, VanDalen KK, et al. Transmission of H6N2 wild bird-origin influenza A virus among multiple bird species in a stacked-cage setting. Arch Virol 2017 May 16. Abstract
submitted by kickingbird at May, 22, 2017 from Arch Virol 2017 May 16 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28508987/)
Live bird markets are common in certain regions of the U.S. and in other regions of the world. We experimentally tested the ability of a wild bird influenza A virus to transmit from index animals to na?ve ... Liu S, Zhang L, Yao Z, Xing L, et al. In vitro and in vivo characterization of a novel H1N1/2009 influenza virus reassortant with an NS gene from a highly pathogenic H5N1 virus, isolated from a human. Arch Virol 2017 May 18. Abstract
submitted by kickingbird at May, 22, 2017 from Arch Virol 2017 May 18 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28523521/)
The triple-reassortant H1N1/2009 influenza A virus, which caused the first influenza pandemic of the 21(st) century, is generally associated with mild disease and a relatively low mortality rate comparable ... JA Besler,etc.,al. A novel A(H7N2) influenza virus isolated from a veterinarian caring for cats in a New York City animal shelter causes mild disease and transmits poorly in the ferret model. J Virol May 17. Abstract
submitted by kickingbird at May, 19, 2017 from J Virol May 17 (via http://jvi.asm.org/content/early/2017/05/12/JVI.00672-17.abs)
In December 2016, a low pathogenic avian influenza (LPAI) A(H7N2) virus was identified as the causative source of an outbreak in a cat shelter in New York City, which subsequently spread to multiple shelters ... Bahl K. et al.. Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses. Mol Ther. 2017 Apr 11. pii: S1525-0016(17)30156-9.. Abstract
submitted by kickingbird at May, 15, 2017 from Mol Ther. 2017 Apr 11. pii: S1525-0016(17)30156-9. (via http://www.cell.com/molecular-therapy-family/molecular-thera)
Recently, the World Health Organization confirmed 120 new human cases of avian H7N9 influenza in China resulting in 37 deaths, highlighting the concern for a potential pandemic and the need for an ... Bui CM. et al.. Influenza A H5N1 and H7N9 in China: A spatial risk analysis. PLoS One. 2017 Apr 4;12(4):e0174980.. Abstract
submitted by kickingbird at May, 15, 2017 from PLoS One. 2017 Apr 4;12(4):e0174980. (via http://journals.plos.org/plosone/article?id=10.1371/journal.)
Background
Zoonotic avian influenza poses a major risk to China, and other parts of the world. H5N1 has remained endemic in China and globally for nearly two decades, and in 2013, a novel zoonotic influenza ... Hussain M, Galvin HD, Haw TY, Nutsford AN, Husain. Drug resistance in influenza A virus: the epidemiology and management. Infection and Drug Resistance 20 April 2017 Volum. Abstract
submitted by kickingbird at May, 15, 2017 from Infection and Drug Resistance 20 April 2017 Volum (via https://www.dovepress.com/drug-resistance-in-influenza-a-vir)
Influenza A virus (IAV) is the sole cause of the unpredictable influenza pandemics and deadly zoonotic outbreaks and constitutes at least half of the cause of regular annual influenza epidemics in ... Zhang ZH, Meng LS, Kong DH, Liu J, Li SZ, Zhou C,. A Suspected Person-to-person Transmission of Avian Influenza A (H7N9) Case in Ward. Chin Med J 2017. Abstract
submitted by kickingbird at May, 15, 2017 from Chin Med J 2017 (via http://www.cmj.org/article.asp?issn=0366-6999;year=2017;volu)
Since throat swab specimens obtained from three adult Chinese patients were confirmed as an avian-origin influenza A (H7N9) virus by local Centers for Disease Control and Prevention (CDC) in 2013,[1] many ... HOFT DF, Lottenbach K, Goll JB, Hill H, et al. Priming Vaccination With Influenza Virus H5 Hemagglutinin Antigen Significantly Increases the Duration of T cell Responses Induced by a Heterologous H5 Booster Vaccination. J Infect Dis. 2016 Oct. Abstract
submitted by kickingbird at May, 14, 2017 from J Infect Dis. 2016 Oct (via https://www.ncbi.nlm.nih.gov/pubmed/27443611)
BACKGROUND: Influenza A(H5N1) virus and other avian influenza virus strains represent major pandemic threats. Like all influenza A virus strains, A(H5N1) viruses evolve rapidly. Innovative immunization ... HIROSE R, Nakaya T, Naito Y, Daidoji T, et al.. Mechanism of human influenza virus RNA persistence and virion survival in feces: mucus protects virions from acid and digestive juices. J Infect Dis. 2017 May 11. Abstract
submitted by kickingbird at May, 14, 2017 from J Infect Dis. 2017 May 11 (via https://www.ncbi.nlm.nih.gov/pubmed/28498998)
Although viral RNA or infectious virions have been detected in the feces of individuals infected with human influenza A/B virus (IAV/IBV), the mechanism of viral survival in the gastrointestinal tract ... Zhu W, Zhou J, Li Z, Yang L, Li X, Huang W, Zou S,. Biological characterisation of the emerged highly pathogenic avian influenza (HPAI) A(H7N9) viruses in humans, in mainland China, 2016 to 2017. Euro Surveill. 2017;22(19):pii=30533.. Abstract
submitted by kickingbird at May, 12, 2017 from Euro Surveill. 2017;22(19):pii=30533. (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
With no or low virulence in poultry, avian influenza A(H7N9) virus has caused severe infections in humans. In the current fifth epidemic wave, a highly pathogenic avian influenza (HPAI) H7N9 ... José Carlos Mancera Gracia, etc.,al. A reassortant H9N2 influenza virus containing 2009 pandemic H1N1 internal-protein genes acquired enhanced pig-to-pig transmission after serial passages in swine. Scientific Reports 7, Article number: 1323 (2017). Abstract
submitted by kickingbird at May, 4, 2017 from Scientific Reports 7, Article number: 1323 (2017) (via http://www.nature.com/articles/s41598-017-01512-x)
Avian H9N2 and 2009 pandemic H1N1 (pH1N1) influenza viruses can infect pigs and humans, raising the concern that H9N2:pH1N1 reassortant viruses could emerge. Such reassortants demonstrated increased replication ... Nakatsukasa A, Kuruma K, Okamatsu M, Hiono T, et a. Potency of whole virus particle and split virion vaccines using dissolving microneedle against challenges of H1N1 and H5N1 influenza viruses in mice. Vaccine 2017 Apr 18.. Abstract
submitted by kickingbird at May, 4, 2017 from Vaccine 2017 Apr 18. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28446669/)
Transdermal vaccination using a microneedle (MN) confers enhanced immunity compared with subcutaneous (SC) vaccination. Here we developed a novel dissolving MN patch for the influenza vaccine. The potencies ... Ivinson K, Deliyannis G, McNabb L, Grollo L, et al. Salivary blockade protects the lower respiratory tract of mice from lethal influenza. J Virol 2017 Apr 26.. Abstract
submitted by kickingbird at May, 4, 2017 from J Virol 2017 Apr 26. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28446669/)
It is possible to model progression of influenza virus from the upper respiratory tract to the lower respiratory tract in the mouse using viral inoculum delivered in a restricted manner to the nose. In ... IZZARD L, Dlugolenski D, Xia Y, McMahon M, et al.. Enhanced immunogenicity following miR-155 incorporation into the influenza A virus genome. Virus Res. 2017 Apr 6. pii: S0168-1702(16)30814. Abstract
submitted by kickingbird at Apr, 20, 2017 from Virus Res. 2017 Apr 6. pii: S0168-1702(16)30814 (via https://www.ncbi.nlm.nih.gov/pubmed/28392443)
Influenza A vaccine efficacy in the elderly is generally poor and so identification of novel molecular adjuvants to improve immunogenicity is important to reduce the overall burden of disease. Short non-coding ... 7514 items, 20/Page, Page[232/376][|<<] [|<] [231] [232] [233] [234] [235] [236] [237] [238] [239] [240] [>|] [>>|] |
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