Zhu W, etc.,al. Enhanced Immune Responses Conferring Cross-Protection by Skin Vaccination With a Tri-Component Influenza Vaccine Using a Microneedle Patch. Front Immunol. 2018 Jul 30;9:1705.. Abstract
submitted by kickingbird at Aug, 20, 2018 from Front Immunol. 2018 Jul 30;9:1705. (via https://www.ncbi.nlm.nih.gov/pubmed/30105019)
Skin vaccination using biodegradable microneedle patch (MNP) technology in vaccine delivery is a promising strategy showing significant advantages over conventional flu shots. In this study, we developed ... Celestino I, etc.,al. Differential Redox State Contributes to Sex Disparities in the Response to Influenza Virus Infection in Male and Female Mice. Front Immunol. 2018 Jul 30;9:1747. Abstract
submitted by kickingbird at Aug, 20, 2018 from Front Immunol. 2018 Jul 30;9:1747 (via https://www.ncbi.nlm.nih.gov/pubmed/30105026)
Influenza virus replicates intracellularly exploiting several pathways involved in the regulation of host responses. The outcome and the severity of the infection are thus strongly conditioned by multiple ... Li X, Li C, Liu JC, Pan YP, Li YG. In vitro effect of Porphyromonas gingivalis combined with influenza A virus on respiratory epithelial cells. Arch Oral Biol. 2018 Apr 5;95:125-133. Abstract
submitted by kickingbird at Aug, 20, 2018 from Arch Oral Biol. 2018 Apr 5;95:125-133 (via https://www.ncbi.nlm.nih.gov/pubmed/30107300)
OBJECTIVE: Respiratory epithelial cells are the first natural barrier against bacteria and viruses; hence, the interactions among epithelial cells, bacteria, and viruses are associated with disease occurrence ... Schechter-Perkins EM, etc.,al. Point-of-care influenza testing does not significantly shorten time to disposition among patients with an influenza-like illness. Am J Emerg Med. 2018 Aug 7. Abstract
submitted by kickingbird at Aug, 20, 2018 from Am J Emerg Med. 2018 Aug 7 (via https://www.ncbi.nlm.nih.gov/pubmed/30107967)
INTRODUCTION: Availability of anti-viral agents and need to isolate infected patients increases the need to confirm the diagnosis of influenza before determining patient disposition.OBJECTIVES: We sought ... Al-Ahdal MN, etc.,al. Entry Inhibition and Modulation of Pro-Inflammatory Immune Response Against Influenza A Virus by a Recombinant Truncated Surfactant Protein D. Front Immunol. 2018 Jul 30;9:1586. Abstract
submitted by kickingbird at Aug, 20, 2018 from Front Immunol. 2018 Jul 30;9:1586 (via https://www.ncbi.nlm.nih.gov/pubmed/30105014)
Surfactant protein D (SP-D) is expressed in the mucosal secretion of the lung and contributes to the innate host defense against a variety of pathogens, including influenza A virus (IAV). SP-D can inhibit ... Vette K, Bareja C, Clark R, Lal A. Establishing thresholds and parameters for pandemic influenza severity assessment, Australia. Bull World Health Organ. 2018 Aug 1;96(8):558-567. Abstract
submitted by kickingbird at Aug, 20, 2018 from Bull World Health Organ. 2018 Aug 1;96(8):558-567 (via https://www.ncbi.nlm.nih.gov/pubmed/30104796)
Objective: To implement the World Health Organization's pandemic influenza severity assessment tool in Australia, using multiple sources of data to establish thresholds and measure influenza severity indicators.Methods: ... Lee JM, etc.,al. Deep mutational scanning of hemagglutinin helps predict evolutionary fates of human H3N2 influenza variants. Proc Natl Acad Sci U S A. 2018 Aug 13. Abstract
submitted by kickingbird at Aug, 20, 2018 from Proc Natl Acad Sci U S A. 2018 Aug 13 (via https://www.ncbi.nlm.nih.gov/pubmed/30104379)
Human influenza virus rapidly accumulates mutations in its major surface protein hemagglutinin (HA). The evolutionary success of influenza virus lineages depends on how these mutations affect HA's functionality ... Wu Y, etc.,al. Prenatal influenza vaccination rescues impairments of social behavior and lamination in a mouse model of autism. J Neuroinflammation. 2018 Aug 13;15(1):228. Abstract
submitted by kickingbird at Aug, 20, 2018 from J Neuroinflammation. 2018 Aug 13;15(1):228 (via https://www.ncbi.nlm.nih.gov/pubmed/30103815)
BACKGROUND: Prenatal infection is a substantial risk factor for neurodevelopmental disorders such as autism in offspring. We have previously reported that influenza vaccination (VAC) during early pregnancy ... Mock DJ, etc.,al. Influenza Virus Infection of Human Lymphocytes Occurs in the Immune Cell Cluster of the Developing Antiviral Response. Viruses. 2018 Aug 10;10(8).. Abstract
submitted by kickingbird at Aug, 20, 2018 from Viruses. 2018 Aug 10;10(8). (via https://www.ncbi.nlm.nih.gov/pubmed/30103427)
Monocytes-macrophages and lymphocytes are recruited to the respiratory tract in response to influenza virus challenge and are exposed to the virus during the establishment of immune defenses. The susceptibility ... Zheng Z, Paul SS, Mo X, Yuan YA, Tan YJ. The Vestigial Esterase Domain of Haemagglutinin of H5N1 Avian Influenza A Virus: Antigenicity and Contribution to Viral Pathogenesis. Vaccines (Basel). 2018 Aug 10;6(3).. Abstract
submitted by kickingbird at Aug, 20, 2018 from Vaccines (Basel). 2018 Aug 10;6(3). (via https://www.ncbi.nlm.nih.gov/pubmed/30103381)
Initial attempts to develop monoclonal antibodies as therapeutics to resolve influenza infections focused mainly on searching for antibodies with the potential to neutralise the virus in vitro with classical ... Daniel Weibel, etc.,al. Narcolepsy and adjuvanted pandemic influenza A (H1N1) 2009 vaccines – Multi-country assessment. Vaccine Available online 16 August 2018. Abstract
submitted by kickingbird at Aug, 18, 2018 from Vaccine Available online 16 August 2018 (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
AbstractBackgroundIn 2010, a safety signal was detected for narcolepsy following vaccination with Pandemrix, an AS03-adjuvanted monovalent pandemic H1N1 influenza (pH1N1) vaccine. To further assess a possible ... Park JE, Ryu Y. Transmissibility and severity of influenza virus by subtype. Infect Genet Evol. 2018 Aug 10. Abstract
submitted by kickingbird at Aug, 16, 2018 from Infect Genet Evol. 2018 Aug 10 (via https://www.ncbi.nlm.nih.gov/pubmed/30103034)
The characteristics of influenza might vary depending on the disease subtype. This review includes previous studies on the transmissibility and severity of influenza and summarizes them by subtype. The ... Stellrecht KA. History of matrix genes mutations within PCR target regions among circulating influenza H3N2 clades over ten-plus-years. J Clin Virol. 2018 Aug 8;107:11-18.. Abstract
submitted by kickingbird at Aug, 16, 2018 from J Clin Virol. 2018 Aug 8;107:11-18. (via https://www.ncbi.nlm.nih.gov/pubmed/30103162)
BACKGROUND: Emerging influenza A/H3N2 clades have been associated with M1 gene mutations which affect the performance of commercial PCR assays.OBJECTIVES AND STUDY DESIGN: The evolution and prevalence ... Guo H, etc.,al. Kinetic analysis of the influenza A virus HA/NA balance reveals contribution of NA to virus-receptor binding and NA-dependent rolling on receptor-containing surfaces. PLoS Pathog. 2018 Aug 13;14(8):e1007233. Abstract
submitted by kickingbird at Aug, 16, 2018 from PLoS Pathog. 2018 Aug 13;14(8):e1007233 (via https://www.ncbi.nlm.nih.gov/pubmed/30102740)
Interactions of influenza A virus (IAV) with sialic acid (SIA) receptors determine viral fitness and host tropism. Binding to mucus decoy receptors and receptors on epithelial host cells is determined ... Wang B, Zhang Y, Jiang W, Zhu L, Li K, Zhou K. GALNT3 inhibits NF-κB signaling during influenza A virus infection. Biochem Biophys Res Commun. 2018 Aug 9. Abstract
submitted by kickingbird at Aug, 16, 2018 from Biochem Biophys Res Commun. 2018 Aug 9 (via https://www.ncbi.nlm.nih.gov/pubmed/30100058)
Protein glycosylation, attaching glycans covalently onto amino acid side chains of protein by various glycosyltransferase, is the most common post-translational modification. The UDP-GalNAc transferase ... Egilmezer E, etc.,al. Systematic review of the impact of point-of-care testing for influenza on the outcomes of patients with acute respiratory tract infection. Rev Med Virol. 2018 Aug 13:e1995. Abstract
submitted by kickingbird at Aug, 16, 2018 from Rev Med Virol. 2018 Aug 13:e1995 (via https://www.ncbi.nlm.nih.gov/pubmed/30101552)
Acute respiratory tract infections are a major cause of morbidity and mortality and represent a significant burden on the health care system. Laboratory testing is required to definitively distinguish ... Sayedahmed EE, etc.,al. A Bovine Adenoviral Vector-Based H5N1 Influenza -Vaccine Provides Enhanced Immunogenicity and Protection at a Significantly Low Dose. Mol Ther Methods Clin Dev. 2018 Jul 17;10:210-222.. Abstract
submitted by kickingbird at Aug, 16, 2018 from Mol Ther Methods Clin Dev. 2018 Jul 17;10:210-222. (via https://www.ncbi.nlm.nih.gov/pubmed/30101154)
Several human and nonhuman adenovirus (AdV) vectors including bovine AdV type 3 (BAdV-3) were developed as gene delivery vectors to supplement and/or elude human AdV (HAdV)-specific neutralizing antibodies ... Zhou F, Zhu CL, Niu ZL, Xu FX, Song H, Liu XH. Influenza A virus inhibits influenza virus replication by inducing IL-37. J Clin Lab Anal. 2018 Aug 11:e22638. Abstract
submitted by kickingbird at Aug, 16, 2018 from J Clin Lab Anal. 2018 Aug 11:e22638 (via https://www.ncbi.nlm.nih.gov/pubmed/30098064)
BACKGROUNDS: The influenza virus is one of the major pathogens that seriously affect human health. It can cause a strong immune response and trigger a series of complications. Interleukin 37 (IL-37) is ... Enkhtaivan G, etc.,al. Berberine-piperazine conjugates as potent influenza neuraminidase blocker. Int J Biol Macromol. 2018 Aug. Abstract
submitted by kickingbird at Aug, 16, 2018 from Int J Biol Macromol. 2018 Aug (via https://www.ncbi.nlm.nih.gov/pubmed/30099043)
In these studies, we analyzed substituted piperazine based berberine analogs conjugated through a pentyloxy side chain for their in vitro and in silico biological effects. All the final analogs were screened ... Nunes B, etc.,al. The 1918-19 Influenza Pandemic in Portugal: A Regional Analysis of Mortality Impact. Am J Epidemiol. 2018 Aug 7. Abstract
submitted by kickingbird at Aug, 16, 2018 from Am J Epidemiol. 2018 Aug 7 (via https://www.ncbi.nlm.nih.gov/pubmed/30099487)
Although many archeo-epidemiological studies have assessed the mortality impact of the 1918-19 influenza pandemic, detailed estimates are not available for Portugal. We applied negative binomial models ... 8181 items, 20/Page, Page[232/410][|<<] [|<] [231] [232] [233] [234] [235] [236] [237] [238] [239] [240] [>|] [>>|] |
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