Aslam S, Rajendran M, Kriti D, Kurland A, Johnson. Generation of a high yield vaccine backbone for influenza B virus in embryonated chicken eggs. NPJ Vaccines. 2023 Feb 10;8(1):12. Abstract submitted by kickingbird at Feb, 12, 2023 from NPJ Vaccines. 2023 Feb 10;8(1):12 (via https://www.nature.com/articles/s41541-023-00603-3) Influenza B virus (IBV) strains are one of the components of seasonal influenza vaccines in both trivalent and quadrivalent formulations. The vast majority of these vaccines are produced in embryonated ... Heinemann AS, Stalp JL, Bonifacio JPP, Silva F, Wi. Silent neonatal influenza A virus infection primes systemic antimicrobial immunity. Front Immunol. 2023 Jan 24;14:1072142. Abstract submitted by kickingbird at Feb, 11, 2023 from Front Immunol. 2023 Jan 24;14:1072142 (via https://www.frontiersin.org/articles/10.3389/fimmu.2023.1072) Infections with influenza A viruses (IAV) cause seasonal epidemics and global pandemics. The majority of these infections remain asymptomatic, especially among children below five years of age. Importantly, ... Vo V, Harrington A, Chang CL, Baker H, Moshi M, Gh. Identification and genome sequencing of an influenza H3N2 variant in wastewater from elementary schools during a surge of influenza A cases in Las Vegas, Nevada. Nevada. Sci Total Environ. 2023 Feb 7:162058. Abstract submitted by kickingbird at Feb, 11, 2023 from Nevada. Sci Total Environ. 2023 Feb 7:162058 (via https://www.sciencedirect.com/science/article/pii/S004896972) Real-time surveillance of infectious diseases at schools or in communities is often hampered by delays in reporting due to resource limitations and infrastructure issues. By incorporating quantitative ... Li K, McCaw JM, Cao P. Enhanced viral infectivity and reduced interferon production are associated with high pathogenicity for influenza viruses. PLoS Comput Biol. 2023 Feb 9;19(2):e1010886. Abstract submitted by kickingbird at Feb, 10, 2023 from PLoS Comput Biol. 2023 Feb 9;19(2):e1010886 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo) Epidemiological and clinical evidence indicates that humans infected with the 1918 pandemic H1N1 influenza virus and highly pathogenic avian H5N1 influenza viruses often displayed severe lung pathology. ... Sims A, Tornaletti LB, Jasim S, Pirillo C, Devlin. Superinfection exclusion creates spatially distinct influenza virus populations. PLoS Biol. 2023 Feb 9;21(2):e3001941. Abstract submitted by kickingbird at Feb, 10, 2023 from PLoS Biol. 2023 Feb 9;21(2):e3001941 (via https://journals.plos.org/plosbiology/article?id=10.1371/jou) Interactions between viruses during coinfections can influence viral fitness and population diversity, as seen in the generation of reassortant pandemic influenza A virus (IAV) strains. However, opportunities ... Kayed AE, Kutkat O, Kandeil A, Moatasim Y, El Tawe. Comparative pathogenic potential of avian influenza H7N3 viruses isolated from wild birds in Egypt and their sensitivity to commercial antiviral drugs. Arch Virol. 2023 Feb 9;168(3):82. Abstract submitted by kickingbird at Feb, 10, 2023 from Arch Virol. 2023 Feb 9;168(3):82 (via https://link.springer.com/article/10.1007/s00705-022-05646-w) Active surveillance and studying the virological features of avian-origin influenza viruses are essential for early warning and preparedness for the next potential pandemic. During our active surveillance ... Huo X, Fu J, Dai Q, Zhu F. Influenza virus subtype/lineage-specific seasonal patterns and age-related infection risk, in Eastern China. J Infect Dev Ctries. 2022 Dec 31;16(12):1928-1932. Abstract submitted by kickingbird at Feb, 10, 2023 from J Infect Dev Ctries. 2022 Dec 31;16(12):1928-1932 (via https://www.jidc.org/index.php/journal/article/view/14887) Introduction: Differences in seasonal pattern and age-related infection risk have been reported between Influenza type A and B, but have not been elaborated at subtype/lineage level.Methodology: All laboratory-confirmed ... Vangeti S, Falck-Jones S, Yu M, ?sterberg B, Liu S. Human influenza virus infection elicits distinct patterns of monocyte and dendritic cell mobilization in blood and the nasopharynx. Elife. 2023 Feb 8;12:e77345. Abstract submitted by kickingbird at Feb, 10, 2023 from Elife. 2023 Feb 8;12:e77345 (via https://elifesciences.org/articles/77345) During respiratory viral infections, the precise roles of monocytes and dendritic cells (DCs) in the nasopharynx in limiting infection and influencing disease severity are incompletely described. We studied ... Pumarola T, Díez-Domingo J, Martinón-Torres F, Red. Excess hospitalizations and mortality associated with seasonal influenza in Spain, 2008-2018. BMC Infect Dis. 2023 Feb 7;23(1):86. Abstract submitted by kickingbird at Feb, 10, 2023 from BMC Infect Dis. 2023 Feb 7;23(1):86 (via https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128) Background: Influenza may trigger complications, particularly in at-risk groups, potentially leading to hospitalization or death. However, due to lack of routine testing, influenza cases are infrequently ... Mollett BC, Everett HE, van Diemen PM, Byrne AMP,. Swine influenza A virus: a neglected virus with pandemic potential. J Med Microbiol. 2023 Jan;72(1). Abstract submitted by kickingbird at Feb, 10, 2023 from J Med Microbiol. 2023 Jan;72(1) (via https://www.microbiologyresearch.org/content/journal/jmm/10.) Swine influenza is an acute respiratory disease of swine caused by swine influenza A virus (SwIAV). The ability of SwIAV to spread bidirectionally from animals to humans (zoonotic), and from humans to ... Wan Z, Zhao Z, Sang J, Jiang W, Chen J, Tang T, Li. Amino Acid Variation at Hemagglutinin Position 193 Impacts the Properties of H9N2 Avian Influenza Virus. J Virol. 2023 Feb 7:e0137922. Abstract submitted by kickingbird at Feb, 8, 2023 from J Virol. 2023 Feb 7:e0137922 (via https://journals.asm.org/doi/10.1128/jvi.01379-22) Despite active control strategies, including the vaccination program in poultry, H9N2 avian influenza viruses possessing mutations in hemagglutinin (HA) were frequently isolated. In this study, we analyzed ... Scheibner D, Salaheldin AH, Bagato O, Zaeck LM, Mo. Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses. PLoS Pathog. 2023 Feb 6;19(2):e1011135. Abstract submitted by kickingbird at Feb, 8, 2023 from PLoS Pathog. 2023 Feb 6;19(2):e1011135 (via https://journals.plos.org/plospathogens/article?id=10.1371/j) Global spread and regional endemicity of H5Nx Goose/Guangdong avian influenza viruses (AIV) pose a continuous threat for poultry production and zoonotic, potentially pre-pandemic, transmission to humans. ... Sun H, Deng G, Sun H, Song J, Zhang W, Li H, Wei X. N-linked glycosylation enhances hemagglutinin stability in avian H5N6 influenza virus to promote adaptation in mammals. PNAS Nexus. 2022 Jun 8;1(3):pgac085. Abstract submitted by kickingbird at Feb, 7, 2023 from PNAS Nexus. 2022 Jun 8;1(3):pgac085 (via https://academic.oup.com/pnasnexus/article/1/3/pgac085/66043) Clade 2.3.4.4 avian H5Ny viruses, namely H5N2, H5N6, and H5N8, have exhibited unprecedented intercontinental spread in poultry. Among them, only H5N6 viruses are frequently reported to infect mammals and ... Scheibner D, Salaheldin AH, Bagato O, Zaeck LM, Mo. Phenotypic effects of mutations observed in the neuraminidase of human origin H5N1 influenza A viruses. PLoS Pathog. 2023 Feb 6;19(2):e1011135. Abstract submitted by kickingbird at Feb, 7, 2023 from PLoS Pathog. 2023 Feb 6;19(2):e1011135 (via https://journals.plos.org/plospathogens/article?id=10.1371/j) Global spread and regional endemicity of H5Nx Goose/Guangdong avian influenza viruses (AIV) pose a continuous threat for poultry production and zoonotic, potentially pre-pandemic, transmission to humans. ... Xie R, Wang W, Gao Y, Liu W, Yue B, Liu S, Fan W,. Evolution and mammalian adaptation of H3 and H10 subtype avian influenza viruses in wild birds in Yancheng Wetland of China. Vet Microbiol. 2023 Jan 23;279:109669.. Abstract submitted by kickingbird at Feb, 4, 2023 from Vet Microbiol. 2023 Jan 23;279:109669. (via https://www.sciencedirect.com/science/article/pii/S037811352) Wild birds play a critical role in avian influenza virus (AIV) ecology and some outbreaks of avian influenza in human originate from wild birds, suggesting that epidemiological surveillance and interspecies-transmission ... Yin X, Wu T, Peng C, Li J, Liu S, Hou G, Jiang W,. Genome sequence analysis of H7N3 subtype avian influenza virus originated from wild birds and its potential infectivity in mice. Virus Genes. 2023 Feb 3. Abstract submitted by kickingbird at Feb, 4, 2023 from Virus Genes. 2023 Feb 3 (via https://link.springer.com/article/10.1007/s11262-023-01968-2) In 2021, an H7N3 avian influenza virus (AIV) was isolated from a mallard in Tianhewan Yellow River National Wetland Park, Ningxia Hui Autonomous Region, China. Sequences analysis showed that this strain ... Tang J, Xu Q, Tang K, Ye X, Cao Z, Zou M, Zeng J,. Susceptibility identification for seasonal influenza A/H3N2 based on baseline blood transcriptome. Front Immunol. 2023 Jan 12;13:1048774.. Abstract submitted by kickingbird at Feb, 1, 2023 from Front Immunol. 2023 Jan 12;13:1048774. (via https://www.frontiersin.org/articles/10.3389/fimmu.2022.1048) Introduction: Influenza susceptibility difference is a widely existing trait that has great practical significance for the accurate prevention and control of influenza.Methods: Here, we focused on the ... Chang P, Sadeyen JR, Bhat S, Daines R, Hussain A,. Risk Assessment of the newly emerged H7N9 avian influenza viruses. Emerg Microbes Infect. 2023 Jan 30:2172965. Abstract submitted by kickingbird at Feb, 1, 2023 from Emerg Microbes Infect. 2023 Jan 30:2172965 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2) Since the first human case in 2013, H7N9 avian influenza viruses (AIVs) have caused more than 1500 human infections with a mortality rate of approximately 40%. Despite large-scale poultry vaccination regimes ... Zhang G, Li B, Raghwani J, Vrancken B, Jia R, Hill. Bidirectional movement of emerging H5N8 avian influenza viruses between Europe and Asia via migratory birds since early 2020. Mol Biol Evol. 2023 Jan 27:msad019. Abstract submitted by kickingbird at Jan, 27, 2023 from Mol Biol Evol. 2023 Jan 27:msad019 (via https://academic.oup.com/mbe/advance-article/doi/10.1093/mol) Migratory birds play a critical role in the rapid spread of highly pathogenic avian influenza (HPAI) H5N8 virus clade 2.3.4.4 across Eurasia. Elucidating the timing and pattern of virus transmission is ... Rolfes MA, Talbot HK, McLean HQ, Stockwell MS, Ell. Household Transmission of Influenza A Viruses in 2021-2022. JAMA. 2023 Jan 26. Abstract submitted by kickingbird at Jan, 27, 2023 from JAMA. 2023 Jan 26 (via https://jamanetwork.com/journals/jama/fullarticle/2800976) Importance: Influenza virus infections declined globally during the COVID-19 pandemic. 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