Thyrsted J, Storgaard J, Blay-Cadanet J, Heinz A,. Influenza A induces lactate formation to inhibit type I IFN in primary human airway epithelium. iScience. 2021 Nov 19;24(11):103300.. Abstract submitted by kickingbird at Nov, 12, 2021 from iScience. 2021 Nov 19;24(11):103300. (via https://www.cell.com/iscience/fulltext/S2589-0042(21)01269-4) Pathogenic viruses induce metabolic changes in host cells to secure the availability of biomolecules and energy to propagate. Influenza A virus (IAV) and severe acute respiratory syndrome corona virus ... Li X, Liu J, Qiu Z, Liao Q, Peng Y, Chen Y, Shu Y. Host-Adaptive Signatures of H3N2 Influenza Virus in Canine. Front Vet Sci. 2021 Oct 20;8:740472. Abstract submitted by kickingbird at Nov, 12, 2021 from Front Vet Sci. 2021 Oct 20;8:740472 (via https://www.frontiersin.org/articles/10.3389/fvets.2021.7404) Wild aquatic birds are the primary natural reservoir of influenza A viruses (IAVs), although a small number of viruses can spill over to mammals and circulate. The focus of IAV infection in mammals was ... Yang J, Yang L, Zhu W, Wang D, Shu Y. Epidemiological and Genetic Characteristics of the H3 Subtype Avian Influenza Viruses in China. China CDC Wkly. 2021 Oct 29;3(44):929-936. Abstract submitted by kickingbird at Nov, 12, 2021 from China CDC Wkly. 2021 Oct 29;3(44):929-936 (via http://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2021.) Avian influenza viruses (AIVs) are naturally preserved in waterfowls and sometimes spill over to infect humans and mammalian animals. The H3 subtype is one of the most prevalent influenza virus subtypes ... Huang W, Li X, Tan M, Cheng Y, Chen T, Wei H, Zeng. Epidemiological and Virological Surveillance of Seasonal Influenza Viruses - China, 2020-2021. China CDC Wkly. 2021 Oct 29;3(44):918-922. Abstract submitted by kickingbird at Nov, 12, 2021 from China CDC Wkly. 2021 Oct 29;3(44):918-922 (via http://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2021.) Introduction: During the coronavirus disease 2019 (COVID-19) pandemic, the circulation of seasonal influenza virus declined globally and remained below previous seasonal levels. We analyzed the results ... Sajjad N, Wang S, Liu P, Chen JL, Chi X, Liu S, Ma. Functional Roles of Non-coding RNAs in the Interaction Between Host and Influenza A Virus. Front Microbiol. 2021 Oct 22;12:742984. Abstract submitted by kickingbird at Nov, 12, 2021 from Front Microbiol. 2021 Oct 22;12:742984 (via https://www.frontiersin.org/articles/10.3389/fmicb.2021.7429) Non-coding RNAs (ncRNAs) are extensively expressed in various cells and tissues, and studies have shown that ncRNAs play significant roles in cell regulation. However, in the past few decades, the knowledge ... Ma Y, Wang Y, Dong C, Gonzalez GX, Song Y, Zhu W,. Influenza NP core and HA or M2e shell double-layered protein nanoparticles induce broad protection against divergent influenza a viruses. Nanomedicine. 2021 Nov 4:102479. Abstract submitted by kickingbird at Nov, 12, 2021 from Nanomedicine. 2021 Nov 4:102479 (via https://www.sciencedirect.com/science/article/abs/pii/S15499) Influenza viral infection causes acute upper respiratory diseases in humans, posing severe risks to global public health. However, current vaccines provide limited protection against mismatched circulating ... Cabeza-Cabrerizo M, Minutti CM, da Costa MP, Cardo. Recruitment of dendritic cell progenitors to foci of influenza A virus infection sustains immunity. Sci Immunol. 2021 Nov 5;6(65):eabi9331.. Abstract submitted by kickingbird at Nov, 8, 2021 from Sci Immunol. 2021 Nov 5;6(65):eabi9331. (via https://www.science.org/doi/10.1126/sciimmunol.abi9331) Protection from infection with respiratory viruses such as influenza A virus (IAV) requires T cell–mediated immune responses initiated by conventional dendritic cells (cDCs) that reside in the respiratory ... Yoo DS, Lee K, Beatriz ML, Chun BC, Belkhiria J, L. Spatio-temporal risk assessment for avian influenza outbreak based on the dynamics of habitat suitability for wild birds. Transbound Emerg Dis. 2021 Nov 4. Abstract submitted by kickingbird at Nov, 8, 2021 from Transbound Emerg Dis. 2021 Nov 4 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14376) Highly pathogenic avian influenza (HPAI) has predominantly damaged the poultry industry worldwide. The fundamental prevention and control strategy for HPAI includes early detection and timely intervention ... Le KT, Stevenson MA, Isoda N, Nguyen LT, Chu DH, N. A systematic approach to illuminate a new hot spot of avian influenza virus circulation in South Vietnam, 2016-2017. Transbound Emerg Dis. 2021 Nov 4.. Abstract submitted by kickingbird at Nov, 5, 2021 from Transbound Emerg Dis. 2021 Nov 4. (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14380) In South Vietnam live bird markets (LBMs) are key in the value chain of poultry products and spread of avian influenza virus (AIV) although they may not be the sole determinant of AIV prevalence. For this ... J Vet Med Sci. 2021 Nov 4. Prior infection with antigenically heterologous low pathogenic avian influenza viruses interferes with the lethality of the H5 highly pathogenic strain in domestic ducks. Soda K, Yamane M, Hidaka C, Miura K, Ung TTH, Nguy. Abstract submitted by kickingbird at Nov, 5, 2021 from Soda K, Yamane M, Hidaka C, Miura K, Ung TTH, Nguy (via https://www.jstage.jst.go.jp/article/jvms/advpub/0/advpub_21) Low and highly pathogenic avian influenza viruses (LPAIVs and HPAIVs, respectively) have been co-circulating in poultry populations in Asian, Middle Eastern, and African countries. In our avian-flu surveillance ... Soda K, Ozaki H, Ito H, Usui T, Okamatsu M, Matsun. Dynamics of invasion and dissemination of H5N6 highly pathogenic avian influenza viruses in 2016-2017 winter in Japan. J Vet Med Sci. 2021 Nov 4. Abstract submitted by kickingbird at Nov, 5, 2021 from J Vet Med Sci. 2021 Nov 4 (via https://www.jstage.jst.go.jp/article/jvms/advpub/0/advpub_21) Large highly pathogenic avian influenza (HPAI) outbreaks caused by clade 2.3.4.4e H5N6 viruses occurred in Japan during the 2016-2017 winter. To date, several reports regarding these outbreaks have been ... Sealy JE, Howard WA, Molesti E, Iqbal M, Temperton. Amino acid substitutions in the H5N1 avian influenza haemagglutinin alter pH of fusion and receptor binding to promote a highly pathogenic phenotype in chickens. J Gen Virol. 2021 Nov;102(11). Abstract submitted by kickingbird at Nov, 3, 2021 from J Gen Virol. 2021 Nov;102(11) (via https://www.microbiologyresearch.org/content/journal/jgv/10.) Highly pathogenic H5N1 avian influenza viruses cause devastating outbreaks in farmed poultry with serious consequences for animal welfare and economic losses. Zoonotic infection of humans through close ... Zeng Y, Wang R, Wang F, Zhang M, Zhang L, Zhu C, Z. Interaction of influenza A virus NS1 and cytoskeleton scaffolding protein α-actinin 4. Virus Genes. 2021 Nov 2. Abstract submitted by kickingbird at Nov, 3, 2021 from Virus Genes. 2021 Nov 2 (via https://link.springer.com/article/10.1007%2Fs11262-021-01876) NS1 (Non-structural protein 1) is a non-structural protein that can highly express when the avian influenza virus infects the host cells. NS1 can interact with various proteins to alter the intracellular ... Harima H, Okuya K, Kajihara M, Ogawa H, Simulundu. Serological and molecular epidemiological study on swine influenza in Zambia. Transbound Emerg Dis. 2021 Nov 1. Abstract submitted by kickingbird at Nov, 2, 2021 from Transbound Emerg Dis. 2021 Nov 1 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14373) Influenza A viruses (IAVs) cause highly contagious respiratory diseases in humans and animals. In 2009, a swine-origin pandemic H1N1 IAV, designated A(H1N1)pdm09 virus, spread worldwide, and has since ... Fan M, Liang B, Zhao Y, Zhang Y, Liu Q, Tian M, Zh. Mutations of 127, 183 and 212 residues on the HA globular head affect the antigenicity, replication and pathogenicity of H9N2 avian influenza virus. Transbound Emerg Dis. 2021 Nov 1. Abstract submitted by kickingbird at Nov, 2, 2021 from Transbound Emerg Dis. 2021 Nov 1 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14363) H9N2 avian influenza virus (AIV), one of the predominant subtypes devastating the poultry industry, has been circulating widely in the poultry population and causing huge economic losses. In this study, ... Lu G, Ou J, Cai S, Lai Z, Zhong L, Yin X, Li S. Canine Interferon-Inducible Transmembrane Protein Is a Host Restriction Factor That Potently Inhibits Replication of Emerging Canine Influenza Virus. Front Immunol. 2021 Oct 14;12:710705. Abstract submitted by kickingbird at Nov, 2, 2021 from Front Immunol. 2021 Oct 14;12:710705 (via https://www.frontiersin.org/articles/10.3389/fimmu.2021.7107) Canine influenza virus (CIV) is an emerging virus that is associated with major hidden hazards to the canine population and public health. Until now, how canine uses its innate immunity to restrict CIV ... Kinoshita T, Watanabe K, Sakurai Y, Nishi K, Yoshi. Co-infection of SARS-CoV-2 and influenza virus causes more severe and prolonged pneumonia in hamsters. Sci Rep. 2021 Oct 28;11(1):21259. Abstract submitted by kickingbird at Nov, 1, 2021 from Sci Rep. 2021 Oct 28;11(1):21259 (via https://www.nature.com/articles/s41598-021-00809-2) Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently a serious public health concern worldwide. Notably, co-infection with other pathogens ... Guo J, Song W, Ni X, Liu W, Wu J, Xia W, Zhou X, W. Pathogen change of avian influenza virus in the live poultry market before and after vaccination of poultry in southern China. Virol J. 2021 Oct 29;18(1):213. Abstract submitted by kickingbird at Nov, 1, 2021 from Virol J. 2021 Oct 29;18(1):213 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-) Background: The fifth wave of H7N9 avian influenza virus caused a large number of human infections and a large number of poultry deaths in China. Since September 2017, mainland China has begun to vaccinate ... Guo J, Wang Y, Zhao C, Gao X, Zhang Y, Li J, Wang. Molecular characterization, receptor binding property and replication in chickens and mice of H9N2 avian influenza viruses isolated from chickens, peafowls and wild birds in eastern China. Emerg Microbes Infect. 2021 Oct 28:1-39. Abstract submitted by kickingbird at Oct, 29, 2021 from Emerg Microbes Infect. 2021 Oct 28:1-39 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2021.1) H9N2 avian influenza viruses are widely prevalent in birds and pose an increasing threat to humans because of their enhanced virulence and transmissibility in mammals. Active surveillance on the prevalence ... Su W, Harfoot R, Su YCF, DeBeauchamp J, Joseph U,. Ancestral sequence reconstruction pinpoints adaptations that enable avian influenza virus transmission in pigs. Nat Microbiol. 2021 Oct 26. Abstract submitted by kickingbird at Oct, 28, 2021 from Nat Microbiol. 2021 Oct 26 (via https://www.nature.com/articles/s41564-021-00976-y) Understanding the evolutionary adaptations that enable avian influenza viruses to transmit in mammalian hosts could allow better detection of zoonotic viruses with pandemic potential. 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