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2022-6-25 10:34:44
Article

Patrono LV, Vrancken B, Budt M, Düx A, Lequime S,. Archival influenza virus genomes from Europe reveal genomic variability during the 1918 pandemic. Nat Commun. 2022 May 10;13(1):2314.  Abstract  
submitted by kickingbird at May, 11, 2022 from Nat Commun. 2022 May 10;13(1):2314 (via https://www.nature.com/articles/s41467-022-29614-9)
The 1918 influenza pandemic was the deadliest respiratory pandemic of the 20th century and determined the genomic make-up of subsequent human influenza A viruses (IAV). Here, we analyze both the first ...

Ryt-Hansen P, Nielsen HG, S?rensen SS, Larsen I, K. The role of gilts in transmission dynamics of swine influenza virus and impacts of vaccination strategies and quarantine management. Porcine Health Manag. 2022 May 5;8(1):19.  Abstract  
submitted by kickingbird at May, 7, 2022 from Porcine Health Manag. 2022 May 5;8(1):19 (via https://porcinehealthmanagement.biomedcentral.com/articles/1)
Background: Along with an expanding global swine production, the commercial housing and management of swine herds, provide an optimal environment for constant circulation of swine influenza virus (swIAV), ...

Van Poelvoorde L, Vanneste K, De Keersmaecker SCJ,. Whole-Genome Sequence Approach and Phylogenomic Stratification Improve the Association Analysis of Mutations With Patient Data in Influenza Surveillance. Front Microbiol. 2022 Apr 19;13:809887.  Abstract  
submitted by kickingbird at May, 7, 2022 from Front Microbiol. 2022 Apr 19;13:809887 (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.8098)
Each year, seasonal influenza results in high mortality and morbidity. The current classification of circulating influenza viruses is mainly focused on the hemagglutinin gene. Whole-genome sequencing (WGS) ...

Zhang Q, Zhang X, Lei X, Wang H, Jiang J, Wang Y,. Influenza A virus NS1 protein hijacks YAP/TAZ to suppress TLR3-mediated innate immune response. PLoS Pathog. 2022 May 3;18(5):e1010505.  Abstract  
submitted by kickingbird at May, 5, 2022 from PLoS Pathog. 2022 May 3;18(5):e1010505 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The Hippo signaling pathway, which is historically considered as a dominator of organ development and homeostasis has recently been implicated as an immune regulator. However, its role in host defense ...

King J, Harder T, Globig A, Stacker L, Günther A,. Highly pathogenic avian influenza virus incursions of subtype H5N8, H5N5, H5N1, H5N4, and H5N3 in Germany during 2020-21. Virus Evol. 2022 Apr 13;8(1):veac035.  Abstract  
submitted by kickingbird at Apr, 30, 2022 from Virus Evol. 2022 Apr 13;8(1):veac035 (via https://academic.oup.com/ve/article/8/1/veac035/6568266)
From October 2020 to July 2021, five different subtypes (H5N8, H5N5, H5N1, H5N4, and H5N3) and seven genotypes of highly pathogenic avian influenza viruses (HPAIV) belonging to clade 2.3.4.4b were detected ...

Yao Q, Mai W, Lian Y, Zhang M, Yao Q, Huang C, Ge. Emergence and Evolution of Novel Canine-Avian Reassortant H3N2 Influenza A Viruses in Duck in Leizhou Peninsula, China. Front Microbiol. 2022 Apr 5;13:857800.  Abstract  
submitted by kickingbird at Apr, 30, 2022 from Front Microbiol. 2022 Apr 5;13:857800 (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.8578)
Avian-to-mammal transmission and mammalian adaptation of avian influenza virus (AIV) are threats to public health and of great concern. The H3 subtype of influenza virus has low pathogenicity and is widely ...

Chauhan RP, Gordon ML. An overview of influenza A virus genes, protein functions, and replication cycle highlighting important updates. Virus Genes. 2022 Apr 26.  Abstract  
submitted by kickingbird at Apr, 27, 2022 from Virus Genes. 2022 Apr 26 (via https://link.springer.com/article/10.1007/s11262-022-01904-w)
The recent research findings on influenza A virus (IAV) genome biology prompted us to present a comprehensive overview of IAV genes, protein functions, and replication cycle. The eight gene segments of ...

Feng H, Yi R, Wu S, Wang G, Sun R, Lin L, Zhu S, N. KAP1 Positively Modulates Influenza A Virus Replication by Interacting with PB2 and NS1 Proteins in Human Lung Epithelial Cells. Viruses. 2022 Mar 26;14(4):689.  Abstract  
submitted by kickingbird at Apr, 24, 2022 from Viruses. 2022 Mar 26;14(4):689 (via https://www.mdpi.com/1999-4915/14/4/689)
Influenza virus only encodes a dozen of viral proteins, which need to use host machinery to complete the viral life cycle. Previously, KAP1 was identified as one host protein that potentially interacts ...

Liu Q, Zhao L, Guo Y, Zhao Y, Li Y, Chen N, Lu Y,. Antigenic Evolution Characteristics and Immunological Evaluation of H9N2 Avian Influenza Viruses from 1994-2019 in China. Viruses. 2022 Mar 30;14(4):726.  Abstract  
submitted by kickingbird at Apr, 24, 2022 from Viruses. 2022 Mar 30;14(4):726 (via https://www.mdpi.com/1999-4915/14/4/726)
The H9N2 subtype avian influenza viruses (AIVs) have been circulating in China for more than 20 years, attracting more and more attention due to the potential threat of them. At present, vaccination is ...

Murakami J, Shibata A, Neumann G, Imai M, Watanabe. Characterization of H9N2 Avian Influenza Viruses Isolated from Poultry Products in a Mouse Model. Viruses. 2022 Mar 30;14(4):728.  Abstract  
submitted by kickingbird at Apr, 24, 2022 from Viruses. 2022 Mar 30;14(4):728 (via https://www.mdpi.com/1999-4915/14/4/728)
Low pathogenic H9N2 avian influenza viruses have spread in wild birds and poultry worldwide. Recently, the number of human cases of H9N2 virus infection has increased in China and other countries, heightening ...

Saito T, Sakuma S, Mine J, Uchida Y, Hangalapura B. Genetic Diversity of the Hemagglutinin Genes of Influenza a Virus in Asian Swine Populations. Viruses. 2022 Apr 1;14(4):747.  Abstract  
submitted by kickingbird at Apr, 24, 2022 from Viruses. 2022 Apr 1;14(4):747 (via https://www.mdpi.com/1999-4915/14/4/747)
Swine influenza (SI) is a major respiratory disease of swine; SI is due to the influenza A virus of swine (IAV-S), a highly contagious virus with zoonotic potential. The intensity of IAV-S surveillance ...

Shi W, Jiang L, Ye M, Wang B, Chang Y, Shan Z, Wan. A Single Amino Acid Residue R144 of SNX16 Affects Its Ability to Inhibit the Replication of Influenza A Virus. Viruses. 2022 Apr 15;14(4):825.  Abstract  
submitted by kickingbird at Apr, 24, 2022 from Viruses. 2022 Apr 15;14(4):825 (via https://www.mdpi.com/1999-4915/14/4/825)
Influenza A virus (IAV) is an important zoonotic pathogen, posing a severe burden for the health of both animals and humans. Many host factors are involved in the life cycle of IAV to regulate its replication. ...

Kim CU, Jeong YJ, Lee P, Lee MS, Park JH, Kim YS,. Extracellular nucleoprotein exacerbates influenza virus pathogenesis by activating Toll-like receptor 4 and the NLRP3 inflammasome. Cell Mol Immunol. 2022 Apr 22.  Abstract  
submitted by kickingbird at Apr, 24, 2022 from Cell Mol Immunol. 2022 Apr 22 (via https://www.nature.com/articles/s41423-022-00862-5)
Host immune responses, such as those initiated by pattern recognition receptor (PRR) activation, are important for viral clearance and pathogenesis. However, little is known about the interactions of viral ...

Zou J, Yu L, Zhu Y, Yang S, Zhao J, Zhao Y, Jiang. Transportin-3 Facilitates Uncoating of Influenza A Virus. Int J Mol Sci. 2022 Apr 8;23(8):4128.  Abstract  
submitted by kickingbird at Apr, 24, 2022 from Int J Mol Sci. 2022 Apr 8;23(8):4128 (via https://www.mdpi.com/1422-0067/23/8/4128)
Influenza A viruses (IAVs) are a major global health threat and in the future, may cause the next pandemic. Although studies have partly uncovered the molecular mechanism of IAV-host interaction, it requires ...

Sreenivasan CC, Uprety T, Reedy SE, Temeeyasen G,. Experimental Infection of Horses with Influenza D Virus. Viruses. 2022 Mar 23;14(4):661..  Abstract  
submitted by kickingbird at Apr, 24, 2022 from Viruses. 2022 Mar 23;14(4):661. (via https://www.mdpi.com/1999-4915/14/4/661)
Antibodies to influenza D virus (IDV) have been detected in horses, but no evidence of disease in the field has been reported. To determine whether IDV is infectious, immunogenic, and pathogenic in horses, ...

Jiang W, Dong C, Liu S, Peng C, Yin X, Liang S, Zh. Emerging Novel Reassortant Influenza A(H5N6) Viruses in Poultry and Humans, China, 2021. Emerg Infect Dis. 2022 May;28(5):1064-1066.  Abstract  
submitted by kickingbird at Apr, 22, 2022 from Emerg Infect Dis. 2022 May;28(5):1064-1066 (via https://wwwnc.cdc.gov/eid/article/28/5/21-2163_article)
A novel highly pathogenic avian influenza A(H5N6) clade 2.3.4.4b virus was isolated from a poultry market in China that a person with a confirmed case had visited. Most genes of the avian and human H5N6 ...

Lv X, Li X, Sun H, Li Y, Peng P, Qin S, Wang W, Li. Highly Pathogenic Avian Influenza A(H5N8) Clade 2.3.4.4b Viruses in Satellite-Tracked Wild Ducks, Ningxia, China, 2020. Emerg Infect Dis. 2022 May;28(5):1039-1042.  Abstract  
submitted by kickingbird at Apr, 22, 2022 from Emerg Infect Dis. 2022 May;28(5):1039-1042 (via https://wwwnc.cdc.gov/eid/article/28/5/21-1580_article)
During October 2020, we identified 13 highly pathogenic avian influenza A(H5N8) clade 2.3.4.4b viruses from wild ducks in Ningxia, China. These viruses were genetically related to H5N8 viruses circulating ...

Li Y, Li X, Lv X, Xu Q, Zhao Z, Qin S, Peng P, Qu. Highly Pathogenic Avian Influenza A(H5Nx) Virus of Clade 2.3.4.4b Emerging in Tibet, China, 2021. Microbiol Spectr. 2022 Apr 21:e0064322.  Abstract  
submitted by kickingbird at Apr, 22, 2022 from Microbiol Spectr. 2022 Apr 21:e0064322 (via https://journals.asm.org/doi/10.1128/spectrum.00643-22)
H5N8 and H5N1 highly pathogenic avian influenza viruses (AIVs) of clade 2.3.4.4b were isolated from dead migratory birds and fecal samples collected in Tibet, China, in May 2021. Phylogenetic analyses ...

Kirkpatrick Roubidoux E, Sano K, McMahon M, Carre?. Novel Epitopes of the Influenza Virus N1 Neuraminidase Targeted by Human Monoclonal Antibodies. J Virol. 2022 Apr 21:e0033222.  Abstract  
submitted by kickingbird at Apr, 22, 2022 from J Virol. 2022 Apr 21:e0033222 (via https://journals.asm.org/doi/10.1128/jvi.00332-22)
Influenza virus neuraminidase (NA)-targeting antibodies are an independent correlate of protection against influenza. Antibodies against the NA act by blocking enzymatic activity, preventing virus release ...

Xu N, Wu Y, Chen Y, Li Y, Yin Y, Chen S, Wu H, Qin. Emerging of H5N6 Subtype Influenza Virus with 129-Glycosylation Site on Hemagglutinin in Poultry in China Acquires Immune Pressure Adaption. Microbiol Spectr. 2022 Apr 21:e0253721.  Abstract  
submitted by kickingbird at Apr, 22, 2022 from Microbiol Spectr. 2022 Apr 21:e0253721 (via https://journals.asm.org/doi/10.1128/spectrum.02537-21)
For an investigation into the effects of glycosylation site modification on hemagglutinin (HA) on the biological characteristics of the H5N6 subtype avian influenza virus (AIV), the HA sequences of H5N6 ...

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