Moatasim Y, Aboulhoda BE, Gomaa M, El Taweel A, Ku. Genetic and pathogenic potential of highly pathogenic avian influenza H5N8 viruses from live bird markets in Egypt in avian and mammalian models. PLoS One. 2024 Oct 29;19(10):e0312134. Abstract
submitted by kickingbird at Oct, 30, 2024 from PLoS One. 2024 Oct 29;19(10):e0312134 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Since its first isolation from migratory birds in Egypt in 2016, highly pathogenic avian influenza (HPAI) H5N8 has caused several outbreaks among domestic poultry in various areas of the country affecting ... Huang QJ, Kim R, Song K, Grigorieff N, Munro JB, S. [preprint]Virion-associated influenza hemagglutinin clusters upon sialic acid binding visualized by cryo-electron tomography. bioRxiv. 2024 Oct 18:2024.10.15.618557. Abstract
submitted by kickingbird at Oct, 29, 2024 from bioRxiv. 2024 Oct 18:2024.10.15.618557 (via https://www.biorxiv.org/content/10.1101/2024.10.15.618557v1)
Influenza viruses are enveloped, negative sense single-stranded RNA viruses covered in a dense layer of glycoproteins. Hemagglutinin (HA) accounts for 80-90% of influenza glycoprotein and plays a role ... Pulit-Penaloza, J.A., Belser, J.A., Brock, N. et a. Transmission of a human isolate of clade 2.3.4.4b A(H5N1) virus in ferrets. Nature (2024). Abstract
submitted by kickingbird at Oct, 29, 2024 from Nature (2024) (via https://www.nature.com/articles/s41586-024-08246-7)
Since 2020, there has been unprecedented global spread of highly pathogenic avian influenza A(H5N1) in wild bird populations with spillover into a variety of mammalian species and sporadically humans. ... Gu, C., Maemura, T., Guan, L. et al. A human isolate of bovine H5N1 is transmissible and lethal in animal models. Nature (2024). Abstract
submitted by kickingbird at Oct, 29, 2024 from Nature (2024) (via https://www.nature.com/articles/s41586-024-08254-7)
The outbreak of clade 2.3.4.4b highly pathogenic avian influenza viruses of the H5N1 subtype (HPAI H5N1) in dairy cows in the US has so far resulted in spillover infections of at least thirteen farm workers1-3, ... Daidoji T, Sadakane H, Garan K, Kawashita N, Arai. The host tropism of current zoonotic H7N9 viruses depends mainly on an acid-labile hemagglutinin with a single amino acid mutation in the stalk region. PLoS Pathog. 2024 Oct 22;20(10):e1012427. Abstract
submitted by kickingbird at Oct, 28, 2024 from PLoS Pathog. 2024 Oct 22;20(10):e1012427 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The incidence of human infection by zoonotic avian influenza viruses, especially H5N1 and H7N9 viruses, has increased. Current zoonotic H7N9 avian influenza viruses (identified since 2013) emerged during ... Heinz Feldmann, etc.,al. [preprint]Orogastric Exposure of Cynomolgus Macaques to Bovine HPAI H5N1 Virus Results in Subclinical Infection. https://doi.org/10.21203/rs.3.rs-5182487/v1. Abstract
submitted by kickingbird at Oct, 28, 2024 from https://doi.org/10.21203/rs.3.rs-5182487/v1 (via https://www.researchsquare.com/article/rs-5182487/v1)
Since early 2022 highly pathogenic avian influenza (HPAI) H5N1 virus infections have been reported in wild aquatic birds and poultry throughout the United States (US) with spillover into several mammalian ... Katherine H Haman, etc.,al. A comprehensive epidemiological approach documenting an outbreak of H5N1 highly pathogenic avian influenza virus clade 2.3.4.4b among gulls, terns, and harbor seals in the Northeastern Pacific. Zoological Medicine. Abstract
submitted by kickingbird at Oct, 27, 2024 from Zoological Medicine (via https://www.frontiersin.org/journals/veterinary-science/arti)
Highly pathogenic avian influenza viruses (HPAIV) H5N1 clade 2.3.4.4b continue to have unprecedented global impacts on wild birds and mammals, with especially significant mortality observed in colonial ... Ye-Ram Seo, etc.,al. Genetic and pathological analysis of hooded cranes (Grus monacha) naturally infected with clade 2.3.4.4b highly pathogenic avian influenza H5N1 virus in South Korea during 2022-2023. Veterinary Epidemiology and Economics. Abstract
submitted by kickingbird at Oct, 27, 2024 from Veterinary Epidemiology and Economics (via https://www.frontiersin.org/journals/veterinary-science/arti)
Highly pathogenic avian influenza (HPAI) subtype H5Nx viruses of the A/Goose/Guangdong/1/1996 (Gs/Gd) lineage have caused substantial economic losses in the poultry industry and represent a significant ... Alkie TN, Nasheri N, Romero-Barrios P, Catford A,. Effectiveness of pasteurization for the inactivation of H5N1 influenza virus in raw whole milk. Food Microbiol. 2025 Jan;125:104653. Abstract
submitted by kickingbird at Oct, 26, 2024 from Food Microbiol. 2025 Jan;125:104653 (via https://www.sciencedirect.com/science/article/abs/pii/S07400)
Highly pathogenic avian influenza (HPAI) clade 2.3.4.4b H5Nx viruses continue to cause episodic incursions and have been detected in more than 12 taxonomic orders encompassing more than 80 avian species, ... Liu Y, Xu J, Wei C, Xu Y, Lyu C, Sun M, Zheng Y, C. Detection of H1N1 Influenza Virus in the Bile of a Severe Influenza Mouse Model. Influenza Other Respir Viruses. 2024 Oct;18(10):e7. Abstract
submitted by kickingbird at Oct, 26, 2024 from Influenza Other Respir Viruses. 2024 Oct;18(10):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70012)
Aims: Influenza virus infection may lead to fatal complications including multi-organ failure and sepsis. The influenza virus was detected in various extra-pulmonary organs in autopsy studies during the ... Dorji T, Dorji K, Gyeltshen S. Evolution of Influenza A(H3N2) Viruses in Bhutan for Two Consecutive Years, 2022 and 2023. Influenza Other Respir Viruses. 2024 Oct;18(10):e7. Abstract
submitted by kickingbird at Oct, 25, 2024 from Influenza Other Respir Viruses. 2024 Oct;18(10):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70028)
Background: Influenza A viruses pose a significant public health threat globally and are characterized by rapid evolution of the hemagglutinin (HA) gene causing seasonal epidemics. The aim of this study ... Jallow MM, Barry MA, Ndiaye NK, Touré CT, Talla C,. Genetic and antigenic characterization of influenza A(H3N2) virus after 13 consecutive years of influenza surveillance in Senegal, 2010-2022. J Med Virol. 2024 Oct;96(10):e70010. Abstract
submitted by kickingbird at Oct, 25, 2024 from J Med Virol. 2024 Oct;96(10):e70010 (via https://onlinelibrary.wiley.com/doi/10.1002/jmv.70010)
Despite decades of influenza surveillance in many African countries, little is known about the evolutionary dynamics of seasonal influenza viruses. This study aimed to characterize the epidemiological, ... Pamela H Brigleb, etc.,al. [preprint]Immune History Modifies Disease Severity to HPAI H5N1 Clade 2.3.4.4b Viral Challenge. https://doi.org/10.1101/2024.10.23.619695. Abstract
submitted by kickingbird at Oct, 25, 2024 from https://doi.org/10.1101/2024.10.23.619695 (via https://www.biorxiv.org/content/10.1101/2024.10.23.619695v1)
The most recent outbreak of highly pathogenic avian H5 influenza (HPAI) virus in cattle is now widespread across the U.S. with spillover events happening to other mammals, including humans. Several human ... Valerie Le Sage, etc.,al. [preprint]Pre-existing H1N1 immunity reduces severe disease with bovine H5N1 influenza virus. https://doi.org/10.1101/2024.10.23.619881. Abstract
submitted by kickingbird at Oct, 25, 2024 from https://doi.org/10.1101/2024.10.23.619881 (via https://www.biorxiv.org/content/10.1101/2024.10.23.619881v1)
The emergence of highly pathogenic H5N1 avian influenza in dairy cattle herds across the United States has caused multiple mild human infections. There is an urgent need to understand the risk of spillover ... Bendall EE, Zhu Y, Fitzsimmons WJ, Rolfes M, Melli. Influenza A virus within-host evolution and positive selection in a densely sampled household cohort over three seasons. Virus Evol. 2024 Oct 3;10(1):veae084. Abstract
submitted by kickingbird at Oct, 25, 2024 from Virus Evol. 2024 Oct 3;10(1):veae084 (via https://academic.oup.com/ve/article/10/1/veae084/7808531)
While influenza A virus (IAV) antigenic drift has been documented globally, in experimental animal infections, and in immunocompromised hosts, positive selection has generally not been detected in acute ... Di Y, Zhang C, Ren Z, Jiang R, Tang J, Yang S, Wan. The self-assembled nanoparticle-based multi-epitope influenza mRNA vaccine elicits protective immunity against H1N1 and B influenza viruses in mice. Front Immunol. 2024 Oct 8;15:1483720. Abstract
submitted by kickingbird at Oct, 25, 2024 from Front Immunol. 2024 Oct 8;15:1483720 (via https://www.frontiersin.org/journals/immunology/articles/10.)
Introduction: The influenza virus is recognized as the primary cause of human respiratory diseases, with the current influenza vaccine primarily offering strain-specific immunity and limited protection ... Juraszek J, Milder FJ, Yu X, Blokland S, van Overv. Engineering a cleaved, prefusion-stabilized influenza B virus hemagglutinin by identification and locking of all six pH switches. PNAS Nexus. 2024 Oct 11;3(10):pgae462. Abstract
submitted by kickingbird at Oct, 25, 2024 from PNAS Nexus. 2024 Oct 11;3(10):pgae462 (via https://academic.oup.com/pnasnexus/article/3/10/pgae462/7818)
Vaccine components based on viral fusion proteins require high stability of the native prefusion conformation for optimal potency and manufacturability. In the case of influenza B virus hemagglutinin (HA), ... Raju N, Kramer KJ, Cavallaro M, Diotti RA, Shiakol. Multiplexed Antibody Sequencing and Profiling of the Human Hemagglutinin-specific Memory B Cell Response following Influenza Vaccination. J Immunol. 2024 Oct 23:ji2400326. Abstract
submitted by kickingbird at Oct, 24, 2024 from J Immunol. 2024 Oct 23:ji2400326 (via https://journals.aai.org/jimmunol/article-abstract/doi/10.40)
Influenza virus is a highly contagious respiratory pathogen causing between 9.4 and 41 million infections per year in the United States in the last decade. Annual vaccination is recommended by the World ... Odin M, Schmeisser F, Soto J, Weir JP. A Rapid Virus-Free Method for Producing Influenza HA Immunogen Needed for Preparation of Influenza Vaccine Potency Antisera Reagents. Influenza Other Respir Viruses. 2024 Oct;18(10):e7. Abstract
submitted by kickingbird at Oct, 24, 2024 from Influenza Other Respir Viruses. 2024 Oct;18(10):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70024)
Background: The potency of inactivated and recombinant influenza vaccines is measured using the single-radial immunodiffusion (SRID) assay. The strain-specific antigen and antibody potency reagents required ... ?al??kan, D. M., Kumar, S., Hinse, S., Schughart,. Molecular characterisation of influenza B virus from the 2017/18 season in primary models of the human lung reveals improved adaptation to the lower respiratory tract. Emerging Microbes & Infections. Abstract
submitted by kickingbird at Oct, 22, 2024 from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
The 2017/18 influenza season was characterized by unusual high numbers of severe infections and hospitalizations. Instead of influenza A viruses, this season was dominated by infections with influenza ... 5577 items, 20/Page, Page[3/279][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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