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2026-2-12 8:04:18
Article

Joshua Mack, Amy Hurford. [preprint]Using an evolutionary epidemiological model of pandemics to estimate the infection fatality ratio for humans infected with avian influenza viruses. https://doi.org/10.64898/2026.01.21.26344526.  Abstract  
submitted by kickingbird at Jan, 24, 2026 from https://doi.org/10.64898/2026.01.21.26344526 (via https://www.medrxiv.org/content/10.64898/2026.01.21.26344526)
The risk of highly pathogenic avian influenza infection to humans is challenging to estimate because many human avian influenza virus (AIV) infections are undetected as they may be asymptomatic, symptomatic ...

?mietanka K, Tarasiuk K, Kycko A, ?wi?toń E, Wyros. Comparative pathogenicity of a virulent field isolate and an NA S122N genetically modified H3N1 avian influenza virus in chickens. Avian Pathol. 2026 Jan 22:1-8.  Abstract  
submitted by kickingbird at Jan, 23, 2026 from Avian Pathol. 2026 Jan 22:1-8 (via https://www.tandfonline.com/doi/full/10.1080/03079457.2026.2)
Low pathogenic avian influenza viruses (LPAIVs) are typically associated with subclinical or mild disease in poultry. However, recent outbreaks involving atypical LPAIV strains, including H3N1 strains ...

Su Y, Wu R, Liu P, Li Z, Pu J, Wang L. Integrated region-specific modeling of H5 avian influenza in Asia using ENSO-based forecasts. One Health. 2026 Jan 7;22:101322.  Abstract  
submitted by kickingbird at Jan, 23, 2026 from One Health. 2026 Jan 7;22:101322 (via https://www.sciencedirect.com/science/article/pii/S235277142)
Highly pathogenic avian influenza (HPAI), particularly of the H5 subtype, remains a persistent threat to poultry, wildlife, and public health across Asia. This study quantifies the influence of the El ...

Rakovskaya A, Lozhkov A, Zabrodskaya Y, Kirenskaya. Neurogenesis decreases in the offspring of mothers infected with influenza A virus. Front Cell Infect Microbiol. 2026 Jan 6;15:1704546.  Abstract  
submitted by kickingbird at Jan, 23, 2026 from Front Cell Infect Microbiol. 2026 Jan 6;15:1704546 (via https://www.frontiersin.org/journals/cellular-and-infection-)
Introduction: Seasonal influenza virus infection during pregnancy poses significant risks to maternal and fetal health, contributing to adverse neurodevelopmental outcomes in offspring. This study investigates ...

John H. Ni, etc.,al. [preprint]Loss of α2,3-linked sialoside in the receptor-binding site of a H5N1 influenza hemagglutinin identified in a human patient. https://doi.org/10.64898/2026.01.19.700419.  Abstract  
submitted by kickingbird at Jan, 23, 2026 from https://doi.org/10.64898/2026.01.19.700419 (via https://www.biorxiv.org/content/10.64898/2026.01.19.700419v1)
In November 2024, an adolescent female in British Columbia was hospitalized presenting with severe symptoms including respiratory failure due to infection with a novel H5N1 subtype influenza strain (BC24). ...

Yuan Z, Wei R, Shang R, Zhang H, Cheng K, Ma S, Zh. Genetic Characterization and Evolutionary Insights of Novel H1N1 Swine Influenza Viruses Identified from Pigs in Shandong Province, China. Viruses. 2026; 18(1):117.  Abstract  
submitted by kickingbird at Jan, 22, 2026 from Viruses. 2026; 18(1):117 (via https://www.mdpi.com/1999-4915/18/1/117)
Influenza A viruses exhibit broad host tropism, infecting multiple species including humans, avian species, and swine. Swine influenza virus (SIV), while primarily circulating in porcine populations, demonstrates ...

Weber J, Ponse NLD, Zhu X, Carrasco MR, Han AX, Fu. The receptor binding properties of H5Ny influenza A viruses have evolved to bind to avian-type mucin-like O-glycans. PLoS Pathog. 2026 Jan 20;22(1):e1013812.  Abstract  
submitted by kickingbird at Jan, 22, 2026 from PLoS Pathog. 2026 Jan 20;22(1):e1013812 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Highly pathogenic H5Ny influenza A viruses are causing unprecedented, season-independent outbreaks across avian and mammalian species, including dairy cattle, a novel reservoir. The sialoside-binding properties ...

Brcko IC, Carius de Souza V, Jeronimo Lima AR, Per. Phylodynamic Reconstruction of H1N1pdm09 Influenza Virus Transmission in Brazil: A Decade of Evolutionary Dynamics. Emerg Microbes Infect. 2026 Jan 19:2620237.  Abstract  
submitted by kickingbird at Jan, 21, 2026 from Emerg Microbes Infect. 2026 Jan 19:2620237 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
The H1N1pdm09 influenza virus, which emerged in 2009 following a unique reassortment of swine-origin gene segments, rapidly replaced the seasonal H1N1 strain and triggered the first influenza pandemic ...

Rahman I, Wight J, Cunningham JT, Ochoa PS, Wallac. Surveillance of live birds for active and past infections reveals the impact of highly pathogenic H5N1 on seabird populations in Atlantic Canada. Can J Microbiol. 2026 Jan 16.  Abstract  
submitted by kickingbird at Jan, 20, 2026 from Can J Microbiol. 2026 Jan 16 (via https://cdnsciencepub.com/doi/10.1139/cjm-2025-0195)
Highly pathogenic avian influenza clade 2.3.4.4b H5Nx viruses (HPAIVs) have caused significant mortality in wild birds. We investigated active avian influenza virus (AIV) infections and assessed seroprevalence ...

Mohammed Nooruzzaman, etc.,al. [preprint]Infection and transmission dynamics of bovine and human influenza A H5N1 viruses in mouse and hamster models. https://doi.org/10.64898/2026.01.17.700113.  Abstract  
submitted by kickingbird at Jan, 20, 2026 from https://doi.org/10.64898/2026.01.17.700113 (via https://www.biorxiv.org/content/10.64898/2026.01.17.700113v1)
Here we investigated the pathogenesis and contact transmission of bovine- and human-derived highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b genotype B3.13 viruses in mammalian models. Using ...

Mohammed Nooruzzaman, etc.,al. [preprint]Recombinant influenza A H5N1 viruses expressing fluorescent and luminescent reporter proteins. https://doi.org/10.64898/2026.01.17.700109.  Abstract  
submitted by kickingbird at Jan, 20, 2026 from https://doi.org/10.64898/2026.01.17.700109 (via https://www.biorxiv.org/content/10.64898/2026.01.17.700109v1)
Highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b viruses present a broad host range, with recent spillover and sustained transmission in dairy cattle in the United States. Replication-competent ...

Biddle JE, House S, Kwon JH, Presti RM, Fritz SA,. Estimating influenza transmission parameters: Comparing two study designs, 2023-2024. Epidemics. 2026 Jan 12;54:100888.  Abstract  
submitted by kickingbird at Jan, 19, 2026 from Epidemics. 2026 Jan 12;54:100888 (via https://www.sciencedirect.com/science/article/pii/S175543652)
Household studies play a critical role in estimating influenza transmission parameters, which are essential for real-time modeling of epidemic and pandemic dynamics to inform influenza control strategies. ...

Xu, G., Chen, Y., Zhu, Y. et al. Resurgence and clinical evolution of influenza A in Chinese children: shifting epidemiology and serological dynamics across pre-, intra-, and post-pandemic eras (2019~2023). BMC Infect Dis (2026).  Abstract  
submitted by kickingbird at Jan, 19, 2026 from BMC Infect Dis (2026) (via https://link.springer.com/article/10.1186/s12879-025-12468-z)
ObjectiveThis study aimed to analyze the epidemiological characteristics and hematologic and inflammatory markers of influenza A in children aged 0–18 years before and after the COVID-19 pandemic to guide ...

Etori A. Moreira, etc.,al. [preprint]Bovine-derived influenza A virus (H5N1) shows efficient replication in well-differentiated human nasal epithelial cells without requiring genetic adaptation. https://doi.org/10.64898/2026.01.16.699876.  Abstract  
submitted by kickingbird at Jan, 18, 2026 from https://doi.org/10.64898/2026.01.16.699876 (via https://www.biorxiv.org/content/10.64898/2026.01.16.699876v1)
Highly pathogenic avian influenza H5N1 viruses of clade 2.3.4.4b have caused widespread avian mortality and sporadic mammalian infections, raising concerns about their potential for efficient replication ...

Dholakia, V., Quantrill, J.L., Richardson, S.A.S.. Polymerase mutations underlie early adaptation of H5N1 influenza virus to dairy cattle and other mammals. Nat Commun (2026).  Abstract  
submitted by kickingbird at Jan, 18, 2026 from Nat Commun (2026) (via https://link.springer.com/article/10.1038/s41467-026-68306-6)
In 2024, an unprecedented outbreak of H5N1 high pathogenicity avian influenza was detected in dairy cattle in the USA resulting in spillbacks into poultry, wild birds and other mammals including humans. ...

Skowronski DM, Ranadheera C, Kaweski SE, Sabaiduc. Cross-reactive H5N1 neuraminidase antibodies by age and influenza A imprinting cohorts of the past century: population-based serosurvey, British Columbia, Canada. J Infect Dis. 2026 Jan 16:jiag030.  Abstract  
submitted by kickingbird at Jan, 17, 2026 from J Infect Dis. 2026 Jan 16:jiag030 (via https://academic.oup.com/jid/advance-article/doi/10.1093/inf)
Background: Pre-existing immunity to emerging influenza viruses informs pandemic risk assessment. We compared cross-reactive neuraminidase (NA) antibody levels against avian influenza A(H5N1) by age and ...

Rosu ME, Westgeest KB, de Graaf M, Hauser BM, Ture. Molecular basis of 60 years of antigenic evolution of human influenza A(H3N2) virus neuraminidase. Cell Host Microbe. 2026 Jan 14;34(1):103-115.e9.  Abstract  
submitted by kickingbird at Jan, 17, 2026 from Cell Host Microbe. 2026 Jan 14;34(1):103-115.e9 (via https://www.cell.com/cell-host-microbe/abstract/S1931-3128(2)
Human influenza A viruses escape antibody-mediated immunity through changes in the hemagglutinin (HA) and neuraminidase (NA) glycoproteins. HA antigenic evolution has been studied extensively, with more ...

Ou G, Ma W, Mo Y, Hu J, Tang T. Absolute humidity drives seasonal influenza A transmission in Hong Kong through social contact modulation: Evidence from compartmental modeling. Infect Dis Model. 2025 Dec 7;11(2):671-682.  Abstract  
submitted by kickingbird at Jan, 17, 2026 from Infect Dis Model. 2025 Dec 7;11(2):671-682 (via https://www.sciencedirect.com/science/article/pii/S246804272)
Background: Prior studies propose a U-shaped humidity-influenza relationship, yet the interplay between humidity-driven contact behaviors and transmission dynamics remains unclear.Objective: The study ...

Xue L, Guo T, Feng Y, San Z, Wang D, Guo L. An influenza D virus in D/Yama2019 lineage from stillbirth fetus of cattle in China. J Vet Med Sci. 2026 Jan 14.  Abstract  
submitted by kickingbird at Jan, 17, 2026 from J Vet Med Sci. 2026 Jan 14 (via https://www.jstage.jst.go.jp/article/jvms/advpub/0/advpub_25)
Influenza D virus (IDV), a respiratory pathogen primarily affecting cattle, is known to have the potential to infect a wide range of animal species. In this study, a novel IDV strain, designated D/JLSL ...

Iervolino, M., Günther, A., Begeman, L. et al. The expanding H5N1 avian influenza panzootic causes high mortality of skuas in Antarctica. Sci Rep (2026).  Abstract  
submitted by kickingbird at Jan, 16, 2026 from Sci Rep (2026) (via https://link.springer.com/article/10.1038/s41598-025-34736-3)
High pathogenicity avian influenza virus H5N1 subtype (H5N1 HPAIV), clade 2.3.4.4b, is expanding its host and geographical range, and invaded Antarctica in 2023. Although mortality in Antarctic wildlife ...

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