Jeong S, Otgontogtokh N, Lee DH, Davganyam B, Lee. Highly Pathogenic Avian Influenza Clade 188.8.131.52 Subtype H5N6 Viruses Isolated from Wild Whooper Swans, Mongolia, 2020. Emerg Infect Dis. 2021 Apr;27(4):1181-1183. Abstract
submitted by kickingbird at Mar, 24, 2021 from Emerg Infect Dis. 2021 Apr;27(4):1181-1183 (via https://wwwnc.cdc.gov/eid/article/27/4/20-3859_article)
We identified clade 184.108.40.206 highly pathogenic avian influenza A(H5N6) viruses from whooper swans (Cygnus cygnus) found dead in Mongolia. The identification of these infections in wild birds in this area ...
Wang J, Jin X, Hu J, Wu Y, Zhang M, Li X, Chen J,. Genetic Evolution Characteristics of Genotype G57 Virus, A Dominant Genotype of H9N2 Avian Influenza Virus. Front Microbiol. 2021 Mar 3;12:633835. Abstract
submitted by kickingbird at Mar, 23, 2021 from Front Microbiol. 2021 Mar 3;12:633835 (via https://www.frontiersin.org/articles/10.3389/fmicb.2021.6338)
This study aimed to investigate the genetic evolution of the H9N2 avian influenza virus (AIV). Whole genome phylogenetic trees were constructed based on 306 H9N2 avian influenza strains collected in China ...
Ding F, Li Y, Huang B, Edwards J, Cai C, Zhang G,. Infection and risk factors of human and avian influenza in pigs in south China. Prev Vet Med. 2021 Mar 5;190:105317. Abstract
submitted by kickingbird at Mar, 22, 2021 from Prev Vet Med. 2021 Mar 5;190:105317 (via https://www.sciencedirect.com/science/article/abs/pii/S01675)
The coinfection of swine influenza (SI) strains and avian/human-source influenza strains in piggeries can contribute to the evolution of new influenza viruses with pandemic potential. This study analyzed ...
Zhu J, Jiang Z, Liu J. The matrix gene of pdm/09 H1N1 contributes to the pathogenicity and transmissibility of SIV in mammals. Vet Microbiol. 2021 Mar 12;255:109039. Abstract
submitted by kickingbird at Mar, 21, 2021 from Vet Microbiol. 2021 Mar 12;255:109039 (via https://www.sciencedirect.com/science/article/pii/S037811352)
The H1N1 influenza virus of swine-origin was responsible for the H1N1 pandemic in 2009 (pdm/09 H1N1), where the virus was transmitted to humans and then spread between people, and its continued circulation ...
Saeed NM, Rashid PMA, Dyary HO. Genetic characterization of highly pathogenic avian influenza A (H5N8) virus isolated from domestic geese in Iraq, 2018. BMC Vet Res. 2021 Mar 19;17(1):124. Abstract
submitted by kickingbird at Mar, 21, 2021 from BMC Vet Res. 2021 Mar 19;17(1):124 (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
Background: Influenza viruses are a continuous threat to avian and mammalian species, causing epidemics and pandemics. After the circulation of H5N1 in 2006, 2015, and 2016 in Iraq, an H5N8 influenza virus ...
Oshansky CM, King J, Lu D, Zhou J, Pavetto C, Horw. Adjuvanted recombinant hemagglutinin H7 vaccine to highly pathogenic influenza A(H7N9) elicits high and sustained antibody responses in healthy adults. NPJ Vaccines. 2021 Mar 19;6(1):41. Abstract
submitted by kickingbird at Mar, 21, 2021 from NPJ Vaccines. 2021 Mar 19;6(1):41 (via https://www.nature.com/articles/s41541-021-00287-7)
An unprecedented number of human infections with avian influenza A(H7N9) in the fifth epidemic wave during the winter of 2016-2017 in China and their antigenic divergence from the viruses that emerged ...
Zinyakov NG, Sosipatorova VY, Andriyasov AV, Ovchi. Genetic analysis of genotype G57 H9N2 avian influenza virus isolate A/chicken/Tajikistan/2379/2018 recovered in Central Asia. Arch Virol. 2021 Mar 19. Abstract
submitted by kickingbird at Mar, 20, 2021 from Arch Virol. 2021 Mar 19 (via https://link.springer.com/article/10.1007/s00705-021-05011-3)
This paper presents genetic data on the full genome analysis of A/chicken/Tajikistan/2379/2018 H9N2 influenza virus isolated in September 2018 from chicken pathological material received from poultry farms ...
Jang H, Ross TM. Hemagglutination Inhibition (HAI) antibody landscapes after vaccination with H7Nx virus like particles. PLoS One. 2021 Mar 18;16(3):e0246613. Abstract
submitted by kickingbird at Mar, 19, 2021 from PLoS One. 2021 Mar 18;16(3):e0246613 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Background: A systemic evaluation of the antigenic differences of the H7 influenza hemagglutinin (HA) proteins, especially for the viruses isolated after 2016, are limited. The purpose of this study was ...
Pu J, Yin Y, Liu J, Wang X, Zhou Y, Wang Z, Sun Y,. Reassortment with dominant chicken H9N2 influenza virus contributed to the fifth H7N9 virus human epidemic. J Virol. 2021 Mar 17:JVI.01578-20. Abstract
submitted by kickingbird at Mar, 19, 2021 from J Virol. 2021 Mar 17:JVI.01578-20 (via https://jvi.asm.org/content/early/2021/03/12/JVI.01578-20)
H9N2 Avian influenza virus (AIV) is regarded as a principal donor of viral genes through reassortment to co-circulating influenza viruses that can result in zoonotic reassortants. Whether H9N2 virus can ...
Halldorsson S, Sader K, Turner J, Calder LJ, Rosen. In situ structure and organization of the influenza C virus surface glycoprotein. Nat Commun. 2021 Mar 16;12(1):1694. Abstract
submitted by kickingbird at Mar, 19, 2021 from Nat Commun. 2021 Mar 16;12(1):1694 (via https://www.nature.com/articles/s41467-021-21818-9)
The lipid-enveloped influenza C virus contains a single surface glycoprotein, the haemagglutinin-esterase-fusion (HEF) protein, that mediates receptor binding, receptor destruction, and membrane fusion ...
Wolf JJ, Xia C, Studstill CJ, Ngo H, Brody SL, And. Influenza A virus NS1 induces degradation of sphingosine 1-phosphate lyase to obstruct the host innate immune response. Virology. 2021 Mar 13;558:67-75. Abstract
submitted by kickingbird at Mar, 19, 2021 from Virology. 2021 Mar 13;558:67-75 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
The type I interferon (IFN)-mediated innate immune response is one of the central obstacles influenza A virus (IAV) must overcome in order to successfully replicate within the host. We have previously ...
Danzy S, Lowen AC, Steel J. A quantitative approach to assess influenza A virus fitness and transmission in guinea pigs. J Virol. 2021 Mar 17:JVI.02320-20. Abstract
submitted by kickingbird at Mar, 19, 2021 from J Virol. 2021 Mar 17:JVI.02320-20 (via https://jvi.asm.org/content/early/2021/03/16/JVI.02320-20)
Efforts to estimate the risk posed by potentially pandemic influenza A viruses (IAV), and to understand the mechanisms governing interspecies transmission, have been hampered by a lack of animal models ...
Zeller MA, Gauger PC, Arendsee ZW, Souza CK, Vince. Machine Learning Prediction and Experimental Validation of Antigenic Drift in H3 Influenza A Viruses in Swine. mSphere. 2021 Mar 17;6(2):e00920-20. Abstract
submitted by kickingbird at Mar, 19, 2021 from mSphere. 2021 Mar 17;6(2):e00920-20 (via https://msphere.asm.org/content/6/2/e00920-20)
The antigenic diversity of influenza A viruses (IAV) circulating in swine challenges the development of effective vaccines, increasing zoonotic threat and pandemic potential. High-throughput sequencing ...
Malausse N, van der Werf S, Naffakh N, Munier S. Influenza B Virus Infection Is Enhanced Upon Heterotypic Co-infection With Influenza A Virus. Front Microbiol. 2021 Feb 25;12:631346. Abstract
submitted by kickingbird at Mar, 17, 2021 from Front Microbiol. 2021 Feb 25;12:631346 (via https://www.frontiersin.org/articles/10.3389/fmicb.2021.6313)
Homotypic co-infections with influenza viruses are described to increase genetic population diversity, to drive viral evolution and to allow genetic complementation. Less is known about heterotypic co-infections ...
Croze M, Kim Y. Inference of population genetic parameters from an irregular time series of seasonal influenza virus sequences. Genetics. 2021 Feb 9;217(2):iyaa039. Abstract
submitted by kickingbird at Mar, 17, 2021 from Genetics. 2021 Feb 9;217(2):iyaa039 (via https://academic.oup.com/genetics/article-abstract/217/2/iya)
Basic summary statistics that quantify the population genetic structure of influenza virus are important for understanding and inferring the evolutionary and epidemiological processes. However, the sampling ...
Gaide N, Foret-Lucas C, Figueroa T, Vergne T, Luca. Viral tropism and detection of clade 220.127.116.11b H5N8 highly pathogenic avian influenza viruses in feathers of ducks and geese. Sci Rep. 2021 Mar 15;11(1):5928. Abstract
submitted by kickingbird at Mar, 17, 2021 from Sci Rep. 2021 Mar 15;11(1):5928 (via https://www.nature.com/articles/s41598-021-85109-5)
Highly Pathogenic Avian Influenza viruses (HPAIVs) display a tissue pantropism, which implies a possible spread in feathers. HPAIV detection from feathers had been evaluated for H5N1 or H7N1 HPAIVs. It ...
Lee J, Li Y, Li Y, Cino-Ozuna AG, Duff M, Lang Y,. Bat influenza vectored NS1-truncated live vaccine protects pigs against heterologous virus challenge. Vaccine. 2021 Mar 11:S0264-410X(21)00268-1. Abstract
submitted by kickingbird at Mar, 16, 2021 from Vaccine. 2021 Mar 11:S0264-410X(21)00268-1 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Swine influenza is an important disease for the swine industry. Currently used whole inactivated virus (WIV) vaccines can induce vaccine-associated enhanced respiratory disease (VAERD) in pigs when the ...
Roosenhoff R, Schutten M, Reed V, Clinch B, van de. Secondary substitutions in the hemagglutinin and neuraminidase genes associated with neuraminidase inhibitor resistance are rare in the Influenza Resistance Information Study (IRIS). Antiviral Res. 2021 Mar 10:105060. Abstract
submitted by kickingbird at Mar, 15, 2021 from Antiviral Res. 2021 Mar 10:105060 (via https://www.sciencedirect.com/science/article/pii/S016635422)
Amino acid substitutions in influenza virus neuraminidase (NA) that cause resistance to neuraminidase inhibitors (NAI) generally result in virus attenuation. However, influenza viruses may acquire secondary ...
Gelenter MD, Mandala VS, Niesen MJM, Sharon DA, Dr. Water orientation and dynamics in the closed and open influenza B virus M2 proton channels. Commun Biol. 2021 Mar 12;4(1):338. Abstract
submitted by kickingbird at Mar, 15, 2021 from Commun Biol. 2021 Mar 12;4(1):338 (via https://www.nature.com/articles/s42003-021-01847-2)
The influenza B M2 protein forms a water-filled tetrameric channel to conduct protons across the lipid membrane. To understand how channel water mediates proton transport, we have investigated the water ...
Lee J, Cho AY, Ko HH, Ping JF, Ma LJ, Chai CF, Noh. Evaluation of insulated isothermal PCR devices for the detection of avian influenza virus. J Virol Methods. 2021 Mar 9:114126. Abstract
submitted by kickingbird at Mar, 15, 2021 from J Virol Methods. 2021 Mar 9:114126 (via https://www.sciencedirect.com/science/article/abs/pii/S01660)
Highly pathogenic avian influenza viruses (HPAIVs) and low pathogenic avian influenza viruses (LPAIVs) represent important threats to the poultry industry and global human health. Due to the high rates ...
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