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2019-5-22 10:05:13
Article

Shen X, Pu Z, Irwin DM, Shen Y. No gene communication between the human H3N2 and H1N1 pandemic 2009 influenza A viruses. J Infect. 2019 Apr 25.  Abstract  
submitted by kickingbird at Apr, 29, 2019 from J Infect. 2019 Apr 25 (via https://www.journalofinfection.com/article/S0163-4453(19)301)
Recently, a study in this journal suggested that the 2014 H1N1 pandemic 2009 (H1N1/pdm2009) had gene communication with 2016/2017 H3N2. The influenza A H1N1/pdm2009 virus, a novel swine-derived, triple ...

Xiang B, et al. Genetic characterization of H7N4 avian influenza virus in China in 2018. J Infect. 2019 Apr 25.  Abstract  
submitted by kickingbird at Apr, 29, 2019 from J Infect. 2019 Apr 25 (via https://www.journalofinfection.com/article/S0163-4453(19)301)
Recent study in this journal reported that the first case of human infection with H7N4 avian influenza virus (AIV) was confirmed in China.1 Subsequently, 11 H7N4 AIVs were isolated from poultries, 4 viruses ...

Guo F, Shen X, Irwin DM, Shen Y. Avian influenza A viruses H5Nx (N1, N2, N6 and N8) show different adaptations of their codon usage patterns to their hosts. J Infect. 2019 Apr 25. pii: S0163-4453(19)30126-4.  Abstract  
submitted by kickingbird at Apr, 29, 2019 from J Infect. 2019 Apr 25. pii: S0163-4453(19)30126-4 (via https://www.journalofinfection.com/article/S0163-4453(19)301)
A recent study in this journal identified three H5 highly pathogenic avian influenza A viruses (HPAIVs) with differing NA subtypes (N1, N6 and N8) and revealed that while the three isolates were all highly ...

Poen MJ, et al. Co-circulation of genetically distinct highly pathogenic avian influenza A clade 2.3.4.4 (H5N6) viruses in wild waterfowl and poultry in Europe and East Asia, 2017~18. Virus Evol. 2019 Apr 22;5(1):vez004.  Abstract  
submitted by kickingbird at Apr, 28, 2019 from Virus Evol. 2019 Apr 22;5(1):vez004 (via https://academic.oup.com/ve/article/5/1/vez004/5476200)
Highly pathogenic avian influenza (HPAI) H5 clade 2.3.4.4 viruses were first introduced into Europe in late 2014 and re-introduced in late 2016, following detections in Asia and Russia. In contrast to ...

Holwerda M, et al. Determining the Replication Kinetics and Cellular Tropism of Influenza D Virus on Primary Well-Differentiated Human Airway Epithelial Cells. Viruses. 2019 Apr 24;11(4)..  Abstract  
submitted by kickingbird at Apr, 28, 2019 from Viruses. 2019 Apr 24;11(4). (via https://www.mdpi.com/1999-4915/11/4/377)
Influenza viruses are notorious pathogens that frequently cross the species barrier with often severe consequences for both animal and human health. In 2011, a novel member of the Orthomyxoviridae family, ...

Novianti AN, et al. Whole-Genome Sequence of an Avian Influenza A/H9N2 Virus Isolated from an Apparently Healthy Chicken at a Live-Poultry Market in Indonesia. Microbiol Resour Announc. 2019 Apr 25;8(17)..  Abstract  
submitted by kickingbird at Apr, 28, 2019 from Microbiol Resour Announc. 2019 Apr 25;8(17). (via https://mra.asm.org/content/8/17/e01671-18)
We isolated an avian influenza A/H9N2 virus from an apparently healthy chicken at a live-poultry market in January 2018. This is the first report of a whole-genome sequence of A/H9N2 virus in Indonesia. ...

Mi?o S, et al. Equine influenza virus in Asia: phylogeographic pattern and molecular features revealed the circulation of an autochthonous lineage. J Virol. 2019 Apr 24..  Abstract  
submitted by kickingbird at Apr, 27, 2019 from J Virol. 2019 Apr 24. (via https://jvi.asm.org/content/early/2019/04/18/JVI.00116-19)
Equine influenza virus (EIV) causes severe acute respiratory disease in horses. Currently, the strains belonging to the H3N8 genotype are divided into two clades, Florida clade 1 (FC1) and Florida clade ...

Kukushkin VI, et al. Highly sensitive detection of influenza virus with SERS aptasensor. PLoS One. 2019 Apr 25;14(4):e0216247.  Abstract  
submitted by kickingbird at Apr, 27, 2019 from PLoS One. 2019 Apr 25;14(4):e0216247 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Highly sensitive and rapid technology of surface enhanced Raman scattering (SERS) was applied to create aptasensors for influenza virus detection. SERS achieves 106?109 times signal amplification, yielding ...

Hom N, Gentles L, Bloom JD, Lee KK. Deep mutational scan of the highly conserved influenza A M1 matrix protein reveals substantial intrinsic mutational tolerance. J Virol. 2019 Apr 24.  Abstract  
submitted by kickingbird at Apr, 27, 2019 from J Virol. 2019 Apr 24 (via https://jvi.asm.org/content/early/2019/04/18/JVI.00161-19)
Influenza A virus matrix protein M1 is involved in multiple stages of the viral infectious cycle. Despite its functional importance, our present understanding of this essential viral protein is limited. ...

Hana A Pawestri, et al. Viral factors associated with the high mortality of human infections with clade 2.1 influenza A/H5N1 virus in Indonesia. Clinical Infectious Diseases 26 April 2019.  Abstract  
submitted by kickingbird at Apr, 27, 2019 from Clinical Infectious Diseases 26 April 2019 (via https://academic.oup.com/cid/advance-article-abstract/doi/10)
AbstractBackgroundSince their emergence in Indonesia in 2005, 200 human infections with clade 2.1 highly pathogenic avian influenza A/H5N1 virus have been reportedassociated with exceptionally high mortality ...

Barman S, et al. Continuing evolution of highly pathogenic H5N1 viruses in Bangladeshi live poultry markets. Emerg Microbes Infect. 2019;8(1):650-661.  Abstract  
submitted by kickingbird at Apr, 25, 2019 from Emerg Microbes Infect. 2019;8(1):650-661 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1)
Since November 2008, we have conducted active avian influenza surveillance in Bangladesh. Clades 2.2.2, 2.3.4.2, and 2.3.2.1a of highly pathogenic avian influenza H5N1 viruses have all been identified ...

Koel BF, et al. Epistatic interactions can moderate the antigenic effect of substitutions in haemagglutinin of influenza H3N2 virus. J Gen Virol. 2019 Apr 24..  Abstract  
submitted by kickingbird at Apr, 25, 2019 from J Gen Virol. 2019 Apr 24. (via https://jgv.microbiologyresearch.org/content/journal/jgv/10.)
We previously showed that single amino acid substitutions at seven positions in haemagglutinin determined major antigenic change of influenza H3N2 virus. Here, the impact of two such substitutions was ...

Westera L, et al. Poly-ADP Ribosyl Polymerase 1 (PARP1) Regulates Influenza A Virus Polymerase. Adv Virol. 2019 Mar 19;2019:8512363..  Abstract  
submitted by kickingbird at Apr, 25, 2019 from Adv Virol. 2019 Mar 19;2019:8512363. (via https://www.hindawi.com/journals/av/2019/8512363/)
Influenza A viruses (IAV) are evolutionarily successful pathogens, capable of infecting a number of avian and mammalian species and responsible for pandemic and seasonal epidemic disease in humans. To ...

Alfardan R, Guo C, Toth LA, Nie D. Impaired Recovery from Influenza A/X-31(H3N2) Infection in Mice with 8-Lipoxygenase Deficiency. Med Sci (Basel). 2019 Apr 12;7(4)..  Abstract  
submitted by kickingbird at Apr, 25, 2019 from Med Sci (Basel). 2019 Apr 12;7(4). (via https://www.mdpi.com/2076-3271/7/4/60)
Lipoxygenase-derived lipid mediators can modulate inflammation and are stimulated in response to influenza infections. We report an effect of 8-lipoxygenase (ALOX8) on the recovery of mice after infection ...

Weigel T, Soliman R, Wolff MW, Reichl U. Hydrophobic-interaction chromatography for purification of influenza A and B virus. J Chromatogr B Analyt Technol Biomed Life Sci. 201.  Abstract  
submitted by kickingbird at Apr, 24, 2019 from J Chromatogr B Analyt Technol Biomed Life Sci. 201 (via https://www.sciencedirect.com/science/article/pii/S157002321)
Options for hydrophobic-interaction chromatography (HIC) for purification of cell culture-derived influenza A and B virus have been assessed using a 96-well plate format using a semi-high-throughput approach. ...

Zhang Y, et al. MORC3 Is a Target of the Influenza A Viral Protein NS1. Structure. 2019 Mar 29. pii: S0969-2126(19)30093-0.  Abstract  
submitted by kickingbird at Apr, 24, 2019 from Structure. 2019 Mar 29. pii: S0969-2126(19)30093-0 (via https://www.cell.com/structure/fulltext/S0969-2126(19)30093-)
Microrchidia 3 (MORC3), a human ATPase linked to several autoimmune disorders, has been characterized both as a negative and positive regulator of influenza A virus. Here, we report that the CW domain ...

Han L, et al. Structural Insights for Anti-Influenza Vaccine Design. Comput Struct Biotechnol J. 2019 Mar 23;17:475-483.  Abstract  
submitted by kickingbird at Apr, 24, 2019 from Comput Struct Biotechnol J. 2019 Mar 23;17:475-483 (via https://www.sciencedirect.com/science/article/pii/S200103701)
Influenza A virus are a persistent and significant threat to human health, and current vaccines do not provide sufficient protection due to antigenic drift, which allows influenza viruses to easily escape ...

Ranaweera A, Ratnayake PU, Ekanayaka EAP, et al. Hydrogen-deuterium exchange supports independent membrane-interfacial fusion peptide and transmembrane domains in subunit 2 of influenza virus hemagglutinin protein, a structured and aqueous-protected. Biochemistry. 2019 Apr 22.  Abstract  
submitted by kickingbird at Apr, 24, 2019 from Biochemistry. 2019 Apr 22 (via https://pubs.acs.org.ccindex.cn/doi/10.1021/acs.biochem.8b01)
The influenza virus hemagglutinin (HA) protein has HA1 and HA2 subunits, which form an initial complex. HA1's bind host cell sialic acids which triggers endocytosis, HA1/HA2 separation, and HA2-mediated ...

Klingen TR, et al. Structures and functions linked to genome-wide adaptation of human influenza A virus. Sci Rep. 2019 Apr 18;9(1):6267.  Abstract  
submitted by kickingbird at Apr, 21, 2019 from Sci Rep. 2019 Apr 18;9(1):6267 (via https://www.nature.com/articles/s41598-019-42614-y)
Human influenza A viruses elicit short-term respiratory infections with considerable mortality and morbidity. While H3N2 viruses circulate for more than 50 years, the recent introduction of pH1N1 viruses ...

Di H, et al. Comparison of nucleic acid extraction methods for next-generation sequencing of avian influenza A virus from ferret respiratory samples. J Virol Methods. 2019 Apr 17.  Abstract  
submitted by kickingbird at Apr, 21, 2019 from J Virol Methods. 2019 Apr 17 (via https://www.sciencedirect.com/science/article/pii/S016609341)
Influenza A virus is a negative-sense RNA virus with a segmented genome consisting of eight RNA segments. Avian influenza A virus (AIV) primarily infects avian hosts and sporadically infects mammals, which ...

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