SHENG Z, Ran Z, Wang D, Hoppe AD, et al. Genomic and evolutionary characterization of a novel influenza-C-like virus from swine. Arch Virol. 2013 Aug 13.. Abstract
submitted by kickingbird at Aug, 20, 2013 from Arch Virol. 2013 Aug 13. (via http://www.ncbi.nlm.nih.gov/pubmed/23942954)
We recently described the isolation of a novel influenza virus from swine exhibiting respiratory disease in the United States that is distantly related to human influenza C virus. Based on genetic, biochemical ... YODSHEEWAN R, Maneewatch S, Srimanote P, Thueng-In. Human monoclonal ScFv specific to NS1 protein inhibits replication of influenza viruses across types and subtypes. Antiviral Res. 2013 Aug 6. pii:. Abstract
submitted by kickingbird at Aug, 20, 2013 from Antiviral Res. 2013 Aug 6. pii: (via http://www.ncbi.nlm.nih.gov/pubmed/23928258)
Currently, there is a need of new anti-influenza agents that target influenza virus proteins other than ion channel M2 and neuraminidase. Non-structural protein-1 (NS1) is a highly conserved multifunctional ... NGUYEN YT, Graitcer SB, Nguyen TH, Tran DN, et al. National surveillance for influenza and influenza-like illness in Vietnam, 2006-2010. Vaccine. 2013 Jul 30. pii: S0264-410X(13)00942. Abstract
submitted by kickingbird at Aug, 11, 2013 from Vaccine. 2013 Jul 30. pii: S0264-410X(13)00942 (via http://www.ncbi.nlm.nih.gov/pubmed/23911781)
Influenza virus infections result in considerable morbidity and mortality both in the temperate and tropical world. Influenza surveillance over multiple years is important to determine the impact and epidemiology ... PANG IK, Pillai PS, Iwasaki A. Efficient influenza A virus replication in the respiratory tract requires signals from TLR7 and RIG-I.. Proc Natl Acad Sci U S A. 2013 Aug 5.. Abstract
submitted by kickingbird at Aug, 11, 2013 from Proc Natl Acad Sci U S A. 2013 Aug 5. (via http://www.ncbi.nlm.nih.gov/pubmed/23918369)
Induction of a proinflammatory response is the hallmark of host innate defense against invading pathogens. Host recognition of influenza A virus (IAV) infection relies on pattern-recognition receptors, ... BOUSSE T, Shore DA, Goldsmith CS, Hossain MJ, et a. Quantitation of influenza virus using field flow fractionation and multi-angle light scattering for quantifying influenza A particles. J Virol Methods. 2013 Jul 31.. Abstract
submitted by kickingbird at Aug, 11, 2013 from J Virol Methods. 2013 Jul 31. (via http://www.ncbi.nlm.nih.gov/pubmed/23916678)
Recent advances in instrumentation and data analysis in field flow fractionation and multi-angle light scattering (FFF-MALS) have enabled greater use of this technique to characterize and quantitate viruses. ... HU J, Hu Z, Mo Y, Wu Q, et al. The PA and HA Genes-Mediated High Viral Load and Intense Innate Immune Response in the Brain Contribute to the High Pathogenicity of H5N1 Avian Influenza Virus in Mallard Ducks. J Virol. 2013 Aug 7. Abstract
submitted by kickingbird at Aug, 11, 2013 from J Virol. 2013 Aug 7 (via http://www.ncbi.nlm.nih.gov/pubmed/23926340)
Most highly pathogenic avian influenza A viruses only cause mild clinical signs in ducks serving as an important natural reservoir of influenza A viruses. However, we isolated two H5N1 viruses that are ... MYERS JL, Wetzel KS, Linderman SL, Li Y, et al. Compensatory hemagglutinin mutations alter antigenic properties of influenza viruses. J Virol. 2013 Aug 7. Abstract
submitted by kickingbird at Aug, 11, 2013 from J Virol. 2013 Aug 7 (via http://www.ncbi.nlm.nih.gov/pubmed/23926344)
Influenza viruses routinely acquire mutations in antigenic sites on the globular head of the hemagglutinin (HA) protein. Since these antigenic sites are near the receptor binding pocket of HA, many antigenic ... GOTO H, Muramoto Y, Noda T, Kawaoka Y, et al. The genome packaging signal of the influenza A virus genome comprises a genome incorporation signal and a genome bundling signal. J Virol. 2013 Aug 7. Abstract
submitted by kickingbird at Aug, 11, 2013 from J Virol. 2013 Aug 7 (via http://www.ncbi.nlm.nih.gov/pubmed/23926345)
The influenza A virus genome comprises eight single-stranded negative-sense RNA segments (vRNAs). All eight vRNAs are selectively packaged into each progeny virion via so-called segment-specific genome ... LOHRMANN F, Dijkman R, Stertz S, Thiel V, et al. Emergence of a C-terminal seven amino acid elongation of NS1 around 1950 conferred a minor growth advantage to former seasonal influenza A viruses. J Virol. 2013 Aug 7.. Abstract
submitted by kickingbird at Aug, 11, 2013 from J Virol. 2013 Aug 7. (via http://www.ncbi.nlm.nih.gov/pubmed/23926347)
Influenza A viruses circulating in humans from ～1950 to ～1987 featured a non-structural (NS1) protein with a C-terminal extension of seven amino acids. The biological significance of this NS1 elongation ... NG S, Fang VJ, Ip DK, Chan KH, et al. Estimation of the association between antibody titers and protection against confirmed influenza virus infection in children. J Infect Dis. 2013 Aug 1.. Abstract
submitted by kickingbird at Aug, 11, 2013 from J Infect Dis. 2013 Aug 1. (via http://www.ncbi.nlm.nih.gov/pubmed/23908481)
Antibody titers measured by hemagglutination inhibition (HAI) correlate with protection against influenza virus infection, and are used to specify criteria for vaccine licensure. In a randomized controlled ... Xian Qi, etc.,al. Probable person to person transmission of novel avian influenza A (H7N9) virus in Eastern China, 2013: epidemiological investigation. BMJ 2013;347:f4752. Abstract
submitted by kickingbird at Aug, 9, 2013 from BMJ 2013;347:f4752 (via http://www.bmj.com/content/347/bmj.f4752)
Abstract
Objective To determine whether the novel avian influenza H7N9 virus can transmit from person to person and its efficiency.
Design Epidemiological investigations conducted after a family cluster ... KOHIO HP, Adamson AL. Glycolytic control of vacuolar-type ATPase activity: A mechanism to regulate influenza viral infection. Virology. 2013 Jul 19. Abstract
submitted by kickingbird at Jul, 30, 2013 from Virology. 2013 Jul 19 (via http://www.ncbi.nlm.nih.gov/pubmed/23876457)
As new influenza virus strains emerge, finding new mechanisms to control infection is imperative. In this study, we found that we could control influenza infection of mammalian cells by altering the level ... SZURGOT I, Szolajska E, Laurin D, Lambrecht B, et. Self-adjuvanting influenza candidate vaccine presenting epitopes for cell-mediated immunity on a proteinaceous multivalent nanoplatform. Vaccine. 2013 Jul 20. Abstract
submitted by kickingbird at Jul, 30, 2013 from Vaccine. 2013 Jul 20 (via http://www.ncbi.nlm.nih.gov/pubmed/23880363)
We exploit the features of a virus-like particle, adenoviral dodecahedron (Ad Dd), for engineering a multivalent vaccination platform carrying influenza epitopes for cell-mediated immunity. The delivery ... HERTZ T, Oshansky CM, Roddam PL, Devincenzo JP, et. HLA targeting efficiency correlates with human T-cell response magnitude and with mortality from influenza A infection. Proc Natl Acad Sci U S A. 2013 Jul 22. Abstract
submitted by kickingbird at Jul, 30, 2013 from Proc Natl Acad Sci U S A. 2013 Jul 22 (via http://www.ncbi.nlm.nih.gov/pubmed/23878211)
Experimental and computational evidence suggests that HLAs preferentially bind conserved regions of viral proteins, a concept we term "targeting efficiency," and that this preference may provide improved ... SHCHERBIK S, Sergent SB, Davis WG, Shu B, et al. Application of real time RT-PCR for the genetic homogeneity and stability tests of the seed candidates for live attenuated influenza vaccine production. J Virol Methods. 2013 Jul 18. pii: S0166-0934. Abstract
submitted by kickingbird at Jul, 30, 2013 from J Virol Methods. 2013 Jul 18. pii: S0166-0934 (via http://www.ncbi.nlm.nih.gov/pubmed/23872266)
Development and improvement of quality control tests for live attenuated vaccines are a high priority because of safety concerns. Live Attenuated Influenza Vaccine (LAIV) viruses are 6:2 reassortants containing ... BUEHLER J, Navi D, Lorusso A, Vincent A, et al. Influenza A virus PB1-F2 protein expression is regulated in a strain-specific manner by sequences located downstream of the PB1-F2 initiation codon. J Virol. 2013 Jul 24. Abstract
submitted by kickingbird at Jul, 30, 2013 from J Virol. 2013 Jul 24 (via http://www.ncbi.nlm.nih.gov/pubmed/23885074)
Translation of influenza A virus PB1-F2 occurs in a second open reading frame (ORF) of the PB1 gene segment. PB1-F2 has been implicated in regulation of polymerase activity, immunopathology, susceptibility ... SULLI C, Banik SS, Schilling J, Moser A, et al. Detection of proton movement directly across viral membranes to identify novel influenza M2 inhibitors. J Virol. 2013 Jul 24. Abstract
submitted by kickingbird at Jul, 30, 2013 from J Virol. 2013 Jul 24 (via http://www.ncbi.nlm.nih.gov/pubmed/23885079)
The influenza M2 protein is a well-validated yet underexploited proton-selective ion channel essential for influenza virus infectivity. Because M2 is a toxic viral ion channel, existing M2 inhibitors have ... DU L, Li Y, Zhao G, Wang L, et al. Highly pathogenic avian influenza H5N1 mutants with air-transmissibility are susceptible to human and animal neutralizing antibodies. J Infect Dis. 2013 Jul 18.. Abstract
submitted by kickingbird at Jul, 30, 2013 from J Infect Dis. 2013 Jul 18. (via http://www.ncbi.nlm.nih.gov/pubmed/23868877)
A laboratory-generated reassortant H5 hemagglutinin (HA)/H1N1 virus containing four mutations in H5N1 HA become airborne transmissible among mammals. Here we constructed 15 H5N1 pseudoviruses containing ... NOH JY, Song JY, Hwang SY, Choi WS, et al. Viral load dynamics in adult patients with A(H1N1)pdm09 influenza. Epidemiol Infect. 2013 Jul 18:1-6. Abstract
submitted by kickingbird at Jul, 30, 2013 from Epidemiol Infect. 2013 Jul 18:1-6 (via http://www.ncbi.nlm.nih.gov/pubmed/23866846)
SUMMARY The dynamics of influenza A viral load in respiratory samples collected from adult A(H1N1)pdm09 influenza patients were investigated. Three respiratory specimens were obtained every 2-4 days and ... L. Zhang et al.. Protection by Face Masks against Influenza A(H1N1)pdm09 Virus on Trans-Pacific Passenger Aircraft, 2009. EID Volume 19, Number 9 September 2013. Abstract
submitted by kickingbird at Jul, 29, 2013 from EID Volume 19, Number 9 September 2013 (via http://wwwnc.cdc.gov/eid/article/19/9/12-1765_article.htm)
In response to several influenza A(H1N1)pdm09 infections that developed in passengers after they traveled on the same 2 flights from New York, New York, USA, to Hong Kong, China, to Fuzhou, China, we assessed ... 8178 items, 20/Page, Page[297/409][|<<] [|<] [291] [292] [293] [294] [295] [296] [297] [298] [299] [300] [>|] [>>|] |
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