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2024-4-20 18:47:38
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KIM JC, Kim HM, Kang YM, Ku KB, et al.. Severe pathogenesis of influenza B virus in pregnant mice. Virology. 2014;448:74-81..  Abstract  
submitted by kickingbird at Dec, 16, 2013 from Virology. 2014;448:74-81. (via http://www.ncbi.nlm.nih.gov/m/pubmed/24314638/)
The study on pathogenesis of influenza B virus during pregnancy is limited. Here, we showed using a mouse model that influenza B virus could cause severe disease including death during pregnancy. Infected ...

KRAMMER F, Margine I, Hai R, Flood A, et al. H3 stalk-based chimeric hemagglutinin influenza virus constructs protect mice from H7N9 challenge. J Virol. 2013 Dec 4.  Abstract  
submitted by kickingbird at Dec, 16, 2013 from J Virol. 2013 Dec 4 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24307585/)
The recent outbreak of H7N9 influenza virus infections in humans in China has raised concerns about the pandemic potential of this strain. Here we test the efficacy of H3-stalk based chimeric hemagglutinin ...

JOB ER, Bottazzi B, Short KR, Deng YM, et al.. A Single Amino Acid Substitution in the Hemagglutinin of H3N2 Subtype Influenza A Viruses Is Associated with Resistance to the Long Pentraxin PTX3 and Enhanced Virulence in Mice. J Immunol. 2013.  Abstract  
submitted by kickingbird at Dec, 16, 2013 from J Immunol. 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24307735/)
The long pentraxin, pentraxin 3 (PTX3), can play beneficial or detrimental roles during infection and disease by modulating various aspects of the immune system. There is growing evidence to suggest that ...

JARU-AMPORNPAN P, Narkpuk J, Wanitchang A, Jongkae. Nucleoprotein of influenza B virus binds to its type A counterpart and disrupts influenza A viral polymerase complex formation. Biochem Biophys Res Commun. 2013 Dec 2. pii: S0006.  Abstract  
submitted by kickingbird at Dec, 16, 2013 from Biochem Biophys Res Commun. 2013 Dec 2. pii: S0006 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24309113/)
Upon co-infection with influenza B virus (FluB), influenza A virus (FluA) replication is substantially impaired. Previously, we have shown that the nucleoprotein of FluB (BNP) can inhibit FluA polymerase ...

TARBET EB, Vollmer AH, Hurst BL, Barnard DL, et al. In vitro activity of favipiravir and neuraminidase inhibitor combinations against oseltamivir-sensitive and oseltamivir-resistant pandemic influenza A (H1N1) virus. Arch Virol. 2013.  Abstract  
submitted by kickingbird at Dec, 16, 2013 from Arch Virol. 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24311151/)
Few anti-influenza drugs are licensed in the United States for the prevention and therapy of influenza A and B virus infections. This shortage, coupled with continuously emerging drug resistance, as detected ...

Zhang A, Huang Y, Tian D, Lau EH, Wan Y, Liu X,. Kinetics of serological responses in influenza A(H7N9)-infected patients correlate with clinical outcome in China, 2013. Euro Surveill. 2013;18(50):pii=20657.  Abstract  
submitted by kickingbird at Dec, 13, 2013 from Euro Surveill. 2013;18(50):pii=20657 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
Introduction A novel avian influenza A(H7N9) infection emerged to cause an outbreak in the Yangtze River delta in early 2013, subsequently spreading to other provinces in China [1-4]. In the first wave ...

Hai, R. et al. Influenza A(H7N9) virus gains neuraminidase inhibitor resistance without loss of in vivo virulence or transmissibility. Nature Communications 4, Article number: 2854.  Abstract  
submitted by kickingbird at Dec, 13, 2013 from Nature Communications 4, Article number: 2854 (via http://www.nature.com/ncomms/2013/131210/ncomms3854/full/nco)
Without baseline human immunity to the emergent avian influenza A(H7N9) virus, neuraminidase inhibitors are vital for controlling viral replication in severe infections. An amino acid change in the viral ...

Rui Xu,m etc.,al. Preferential Recognition of Avian-Like Receptors in Human Influenza A H7N9 Viruses. Science 6 December 2013.  Abstract  
submitted by kickingbird at Dec, 10, 2013 from Science 6 December 2013 (via http://www.sciencemag.org/content/342/6163/1230.abstract?sid)
The 2013 outbreak of avian-origin H7N9 influenza in eastern China has raised concerns about its ability to transmit in the human population. The hemagglutinin glycoprotein of most human H7N9 viruses carries ...

Liu W, Yang K, Qi X, Xu K, Ji H, Ai J, Ge A, Wu Y,. Spatial and temporal analysis of human infection with avian influenza A(H7N9) virus in China, 2013. Euro Surveill. 2013;18(47):pii=20640..  Abstract  
submitted by kickingbird at Nov, 22, 2013 from Euro Surveill. 2013;18(47):pii=20640. (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
Descriptive and geographic information system methods were used to depict the spatial and temporal characteristics of the outbreak of human infection with a novel avian influenza A(H7N9) virus in mainland ...

N Cao, Etc.,al. Avian influenza A (H5N1) virus antibodies in pigs and residents of swine farms, southern China. JCV.  Abstract  
submitted by kickingbird at Nov, 18, 2013 from JCV (via http://www.journalofclinicalvirology.com/article/S1386-6532()
Abstract  Background Since 1997, the H5 avian influenza viruses (AIVs) circulating in China have become an international concern. Clade 2.3.2 of H5N1 AIVs is genetically distinct from the viruses ...

WONG KK, Jain S, Blanton L, Dhara R, et al. Influenza-Associated Pediatric Deaths in the United States, 2004-2012. Pediatrics. 2013 Oct 28.  Abstract  
submitted by kickingbird at Nov, 4, 2013 from Pediatrics. 2013 Oct 28 (via http://www.ncbi.nlm.nih.gov/pubmed/24167165)
BACKGROUND:Influenza-associated deaths in children occur annually. We describe the epidemiology of influenza-associated pediatric deaths from the 2004-2005 through the 2011-2012 influenza seasons.METHODS:Deaths ...

MEDINA J, Guillot V, Totain E, Rouleau M, et al. Vero/CHOK1, a novel mixture of cell lines that is optimal for the rescue of influenza A vaccine seeds. J Virol Methods. 2013 Oct 23.  Abstract  
submitted by kickingbird at Nov, 4, 2013 from J Virol Methods. 2013 Oct 23 (via http://www.ncbi.nlm.nih.gov/pubmed/24161812)
Seasonal and pandemic influenza vaccine manufacturing is challenged with a tight production schedule. Reverse genetics constitutes a rapid method for creating viruses. Vero and CHOK1 cells were found to ...

ALYMOVA IV, Samarasinghe A, Vogel P, Green AM, et. A novel cytotoxic sequence contributes to influenza A protein PB1-F2 pathogenicity and predisposition to secondary bacterial infection. J Virol. 2013 Oct 30.  Abstract  
submitted by kickingbird at Nov, 4, 2013 from J Virol. 2013 Oct 30 (via http://www.ncbi.nlm.nih.gov/pubmed/24173220)
Enhancement of cell death is a distinguishing feature of H1N1 influenza virus A/Puerto Rico/8/34 protein PB1-F2. Comparing the sequences (amino acids [a.a.] 61-87 using PB1-F2 a.a. numbering) of the PB1-F2-derived ...

CLARIDGE JK, Aittoniemi J, Cooper DM, Schnell JR,. Isotropic bicelles stabilize the juxtamembrane region of the influenza M2 protein for solution NMR studies.. Biochemistry. 2013 Oct 29.  Abstract  
submitted by kickingbird at Nov, 4, 2013 from Biochemistry. 2013 Oct 29 (via http://www.ncbi.nlm.nih.gov/pubmed/24168642)
The protein M2 from influenza is a tetrameric membrane protein with several roles in the viral life cycle. The transmembrane helix (TMH) of M2 has proton channel activity that is required for unpackaging ...

ZHAO H, Yang J, Li K, Ding X, et al. Proteomic analysis at the subcellular level for host targets against influenza A virus (H1N1).. Antiviral Res. 2013 Oct 22. pii: S0166-3542(13)002.  Abstract  
submitted by kickingbird at Nov, 4, 2013 from Antiviral Res. 2013 Oct 22. pii: S0166-3542(13)002 (via http://www.ncbi.nlm.nih.gov/pubmed/24161511)
Influenza viruses (IVs) trigger a series of intracellular signaling events and induce complex cellular responses from the infected host cell. Accumulating evidence suggests that host cell proteins play ...

HJ Yu, etc.,al. Effect of closure of live poultry markets on poultry-to-person transmission of avian influenza A H7N9 virus: an ecological study. The Lancet, doi:10.1016/S0140-6736(13)61904-2.  Abstract  
submitted by kickingbird at Nov, 4, 2013 from The Lancet, doi:10.1016/S0140-6736(13)61904-2 (via http://www.thelancet.com/journals/lancet/article/PIIS0140-67)
Background Transmission of the novel avian influenza A H7N9 virus seems to be predominantly between poultry and people. In the major Chinese cities of Shanghai, Hangzhou, Huzhou, and Nanjing—where most ...

HALSEY NA, Griffioen M, Dreskin SC, Dekker CL, et. Immediate hypersensitivity reactions following monovalent 2009 pandemic influenza A (H1N1) vaccines: Reports to VAERS. Vaccine. 2013 Oct 8..  Abstract  
submitted by kickingbird at Oct, 20, 2013 from Vaccine. 2013 Oct 8. (via http://www.ncbi.nlm.nih.gov/pubmed/24120547)
BACKGROUND: Hypersensitivity disorders following vaccinations are a cause for concern. OBJECTIVE: To determine the type and rate by age, gender, and vaccine received for reported hypersensitivity ...

KIMBLE JB, Angel M, Wan H, Sutton TC, et al. Alternative reassortment events leading to transmissible H9N1 influenza viruses in the ferret model. J Virol. 2013 Oct 16..  Abstract  
submitted by kickingbird at Oct, 20, 2013 from J Virol. 2013 Oct 16. (via http://www.ncbi.nlm.nih.gov/pubmed/24131710)
Influenza A H9N2 viruses are common poultry pathogens that occasionally infect swine and humans. It has been shown previously with H9N2 viruses, reassortment can generate novel viruses with increased transmissibility. ...

SUN H, Sun Y, Pu J, Zhang Y, et al. Comparative virus replication and host innate response in human cells infected with 3 prevalent clades (2.3.4, 2.3.2 and 7) of highly pathogenic avian influenza H5N1 viruses. J Virol. 2013 Oct 16.  Abstract  
submitted by kickingbird at Oct, 20, 2013 from J Virol. 2013 Oct 16 (via http://www.ncbi.nlm.nih.gov/pubmed/24131718)
Highly pathogenic avian influenza H5N1 virus clades 2.3.4, 2.3.2 and 7 are the dominant co-circulating H5N1 viruses in poultry in China. However, humans appear to be clinically susceptible mostly to the ...

BARANOVICH T, Burnham AJ, Marathe BM, Armstrong J,. The Neuraminidase Inhibitor Oseltamivir is Effective against A/Anhui/1/2013 (H7N9) Influenza Virus in a Mouse Model of Acute Respiratory Distress Syndrome.. J Infect Dis. 2013 Oct 16.  Abstract  
submitted by kickingbird at Oct, 20, 2013 from J Infect Dis. 2013 Oct 16 (via http://www.ncbi.nlm.nih.gov/pubmed/24133191)
Background.?High mortality and uncertainty about the effectiveness of neuraminidase inhibitors (NAIs) in humans infected with A (H7N9) influenza viruses are public health concerns.Methods.?Susceptibility ...

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