Turgeon N, et al. Design and Validation with Influenza A Virus of an Aerosol Transmission Chamber for Ferrets. Int J Environ Res Public Health. 2019 Feb 19;16(4). Abstract
submitted by kickingbird at Feb, 24, 2019 from Int J Environ Res Public Health. 2019 Feb 19;16(4) (via https://www.mdpi.com/1660-4601/16/4/609)
Background: The importance of aerosols in the spread of viruses like influenza is still a subject of debate. Indeed, most viruses can also be transmitted through direct contact and droplets. Therefore, ...
Kandula S, Shaman J. Near-term forecasts of influenza-like illness: An evaluation of autoregressive time series approaches. Epidemics. 2019 Jan 17. Abstract
submitted by kickingbird at Feb, 24, 2019 from Epidemics. 2019 Jan 17 (via https://www.ncbi.nlm.nih.gov/pubmed/30792135)
Seasonal influenza in the United States is estimated to cause 9-35 million illnesses annually, with resultant economic burden amounting to $47-$150 billion. Reliable real-time forecasts of influenza can ...
Lei N, et al. Molecular evolution of influenza B virus during 2011-2017 in Chaoyang, Beijing, suggesting the free influenza vaccine policy. Sci Rep. 2019 Feb 21;9(1):2432.. Abstract
submitted by kickingbird at Feb, 24, 2019 from Sci Rep. 2019 Feb 21;9(1):2432. (via https://www.nature.com/articles/s41598-018-38105-1)
Two influenza B virus lineages, B/Victoria and B/Yamagata, are co-circulating in human population. While the two lineages are serologically distinct and TIV only contain one lineage. It is important to ...
Zhang W, et al. Genetic Evolution and Molecular Selection of the HE Gene of Influenza C Virus. Viruses. 2019 Feb 19;11(2). Abstract
submitted by kickingbird at Feb, 24, 2019 from Viruses. 2019 Feb 19;11(2) (via https://www.mdpi.com/1999-4915/11/2/167)
Influenza C virus (ICV) was first identified in humans and swine, but recently also in cattle, indicating a wider host range and potential threat to both the livestock industry and public health than was ...
Jiao H, et al. MicroRNA expression profiles from HEK293 cells expressing H5N1 avian influenza virus non-structural protein 1. Innate Immun. 2019 Feb;25(2):110-117. Abstract
submitted by kickingbird at Feb, 22, 2019 from Innate Immun. 2019 Feb;25(2):110-117 (via https://journals.sagepub.com/doi/full/10.1177/17534259198263)
H5N1 avian influenza poses a serious threat to the poultry industry and human health. Non-structural protein 1 (NS1) plays an important role in the replication and pathogenesis of avian influenza virus ...
Sambala EZ, Ndwandwe DE, Imaan LM, Wiysonge CS. Evaluation of influenza surveillance systems in sub-Saharan Africa: a systematic review protocol. BMJ Open. 2019 Jan 28;9(1):e023335.. Abstract
submitted by kickingbird at Feb, 22, 2019 from BMJ Open. 2019 Jan 28;9(1):e023335. (via https://bmjopen.bmj.com/content/9/1/e023335.long)
INTRODUCTION: Influenza infrastructure systems are crucial for maintaining surveillance operations, and for mitigating and responding to the disease. The role of surveillance is to isolate and identify ...
Qiu Y, et al. Viral infection detection using metagenomics technology in six poultry farms of eastern China. PLoS One. 2019 Feb 20;14(2):e0211553. Abstract
submitted by kickingbird at Feb, 21, 2019 from PLoS One. 2019 Feb 20;14(2):e0211553 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
With rapidly increasing animal pathogen surveillance requirements, new technologies are needed for a comprehensive understanding of the roles of pathogens in the occurrence and development of animal diseases. ...
Tseng YC, et al. Egg-based influenza split virus vaccine with monoglycosylation induces cross-strain protection against influenza virus infections. Proc Natl Acad Sci U S A. 2019 Feb 19. Abstract
submitted by kickingbird at Feb, 21, 2019 from Proc Natl Acad Sci U S A. 2019 Feb 19 (via https://www.pnas.org/content/early/2019/02/12/1819197116)
Each year influenza virus infections cause hundreds of thousands of deaths worldwide and a significant level of morbidity with major economic burden. At the present time, vaccination with inactivated virus ...
Yokomichi H, et al. Incidence of hospitalisation for severe complications of influenza virus infection in Japanese patients between 2012 and 2016: a cross-sectional study using routinely collected administrative data. BMJ Open. 2019 Jan 17;9(1):e024687. Abstract
submitted by kickingbird at Feb, 21, 2019 from BMJ Open. 2019 Jan 17;9(1):e024687 (via https://bmjopen.bmj.com/content/9/1/e024687)
OBJECTIVE: To calculate the incidence of hospitalisation due to acute respiratory failure, pneumonia, acute respiratory distress syndrome (ARDS), febrile seizures and encephalitis/encephalopathy among ...
Gerlach T, Elbahesh H, Saletti G, Rimmelzwaan G. Recombinant influenza A viruses as vaccine vectors. Expert Rev Vaccines. 2019 Feb 19.. Abstract
submitted by kickingbird at Feb, 21, 2019 from Expert Rev Vaccines. 2019 Feb 19. (via https://www.ncbi.nlm.nih.gov/pubmed/30777467)
Various viruses, including poxviruses, adenoviruses and vesicular stomatitis virus, have been considered as vaccine vectors for the delivery of antigens of interest in the development of vaccines against ...
Smieszek T, Lazzari G, Salathé M. Assessing the Dynamics and Control of Droplet- and Aerosol-Transmitted Influenza Using an Indoor Positioning System. Sci Rep. 2019 Feb 18;9(1):2185.. Abstract
submitted by kickingbird at Feb, 21, 2019 from Sci Rep. 2019 Feb 18;9(1):2185. (via https://www.ncbi.nlm.nih.gov/pubmed/30778136)
There is increasing evidence that aerosol transmission is a major contributor to the spread of influenza. Despite this, virtually all studies assessing the dynamics and control of influenza assume that ...
Koutsakos M, et al. Human CD8+ T cell cross-reactivity across influenza A, B and C viruses. Nat Immunol. 2019 Feb 18.. Abstract
submitted by kickingbird at Feb, 21, 2019 from Nat Immunol. 2019 Feb 18. (via https://www.nature.com/articles/s41590-019-0320-6)
Influenza A, B and C viruses (IAV, IBV and ICV, respectively) circulate globally and infect humans, with IAV and IBV causing the most severe disease. CD8+ T cells confer cross-protection against IAV strains, ...
Hu Y, et al. Immunogenicity and safety of a trivalent inactivated influenza vaccine produced in Shenzhen, China versus a comparator influenza vaccine: a phase IV randomized study. Hum Vaccin Immunother. 2019 Feb 19. Abstract
submitted by kickingbird at Feb, 21, 2019 from Hum Vaccin Immunother. 2019 Feb 19 (via https://www.ncbi.nlm.nih.gov/pubmed/30779689)
Seasonal influenza causes substantial morbidity and mortality in China, which largely results from limited vaccine accessibility and poor vaccination coverage. Since 2013, Sanofi Pasteur's facilities in ...
Rüdiger D, Kupke SY, Laske T, Zmora P, Reichl U. Multiscale modeling of influenza A virus replication in cell cultures predicts infection dynamics for highly different infection conditions. PLoS Comput Biol. 2019 Feb 19;15(2):e1006819.. Abstract
submitted by kickingbird at Feb, 21, 2019 from PLoS Comput Biol. 2019 Feb 19;15(2):e1006819. (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Influenza A viruses (IAV) are commonly used to infect animal cell cultures for research purposes and vaccine production. Their replication is influenced strongly by the multiplicity of infection (MOI), ...
Ilyushina NA, Dickensheets H, Donnelly RP. A comparison of interferon gene expression induced by influenza A virus infection of human airway epithelial cells from two different donors. Virus Res. 2019 Feb 16. Abstract
submitted by kickingbird at Feb, 21, 2019 from Virus Res. 2019 Feb 16 (via https://www.ncbi.nlm.nih.gov/pubmed/30779949)
Influenza is an acute respiratory disease that can cause local annual epidemics and worldwide pandemics of different morbidity and mortality. Our understanding of host factors that modulate the frequency ...
Ren L, et al. Influenza A virus (H1N1) triggers a hypoxic response by stabilizing hypoxia-inducible factor-1α via inhibition of proteasome. Virology. 2019 Feb 11;530:51-58. Abstract
submitted by kickingbird at Feb, 21, 2019 from Virology. 2019 Feb 11;530:51-58 (via https://www.ncbi.nlm.nih.gov/pubmed/30780125)
Virus reprogramming of host cellular function is a critical strategy for viral survival and replication. A better understanding of virus-host interaction may provide new potential avenues for the treatment ...
Roy Chowdhury I, Yeddula SGR, Kim SH. Pathogenicity and Transmissibility of North American H7 Low Pathogenic Avian Influenza Viruses in Chickens and Turkeys. Viruses. 2019 Feb 16;11(2). Abstract
submitted by kickingbird at Feb, 21, 2019 from Viruses. 2019 Feb 16;11(2) (via https://www.ncbi.nlm.nih.gov/pubmed/30781528)
Low pathogenic avian influenza (LPAI) viruses can silently circulate in poultry and wild aquatic birds and potentially mutate into highly pathogenic avian influenza (HPAI) viruses. In the U.S., recent ...
Zhang T, Zhao H, Wang J, Han GZ. Wild birds do not harbor higher diversity of influenza virus internal genes than poultry. Virology. 2019 Feb 7;530:59-64. Abstract
submitted by kickingbird at Feb, 20, 2019 from Virology. 2019 Feb 7;530:59-64 (via https://www.ncbi.nlm.nih.gov/pubmed/30776509)
Avian influenza A virus (AIV) has threatened global economy and public health. Wild birds have long been thought to serve as the natural reservoir of influenza virus, and thus it is expected that wild ...
Hu Q, Gilley RP, Dube PH. House dust mite exposure attenuates influenza A infection in a mouse model of pulmonary allergic inflammation. Microb Pathog. 2019 Feb 15.. Abstract
submitted by kickingbird at Feb, 20, 2019 from Microb Pathog. 2019 Feb 15. (via https://www.ncbi.nlm.nih.gov/pubmed/30776411)
Environmental allergens elicit complex immune responses in the lungs that can promote the development of asthma or exacerbate preexisting asthma in susceptible individuals. House dust mites are one of ...
Fu Y, et al. Infection Studies in Pigs and Porcine Airway Epithelial Cells Reveal an Evolution of A(H1N1)pdm09 Influenza A Viruses Toward Lower Virulence. J Infect Dis. 2019 Feb 18.. Abstract
submitted by kickingbird at Feb, 20, 2019 from J Infect Dis. 2019 Feb 18. (via https://www.ncbi.nlm.nih.gov/pubmed/30776304)
We analyzed the virulence of pandemic H1N1 2009 influenza A viruses in vivo and in vitro. Selected viruses isolated in 2009, 2010, 2014, and 2015 were assessed using an aerosol-mediated high-dose infection ...
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