Broich L, Fu Y, Sieben C. Live-Cell Single-Molecule Imaging of Influenza A Virus-Receptor Interaction. Methods Mol Biol. 2025;2890:89-101. Abstract
submitted by kickingbird at Feb, 3, 2025 from Methods Mol Biol. 2025;2890:89-101 (via https://link.springer.com/protocol/10.1007/978-1-0716-4326-6)
Influenza A viruses are a major health care burden, and their biology has been intensely studied for decades. However, many details of virus infection are still elusive, requiring the development of refined ... Pathak T, Gupta K, Kumar N, Banerjee I. Monitoring Influenza A Virus Entry Using Quantitative Fluorescence Microscopy. Methods Mol Biol. 2025;2890:103-123. Abstract
submitted by kickingbird at Feb, 3, 2025 from Methods Mol Biol. 2025;2890:103-123 (via https://link.springer.com/protocol/10.1007/978-1-0716-4326-6)
Influenza A virus (IAV) is a major threat to global human health and is a topic of intense research. With the continuous problem of seasonal influenza and the threat of potential pandemics due to frequent ... Nakano M, Noda T. Purification and Ultramicroscopic Observation of the Influenza A Virus Ribonucleoprotein Complex. Methods Mol Biol. 2025;2890:141-149. Abstract
submitted by kickingbird at Feb, 3, 2025 from Methods Mol Biol. 2025;2890:141-149 (via https://link.springer.com/protocol/10.1007/978-1-0716-4326-6)
Influenza A virus (IAV) has an eight-segmented, single-stranded, negative-sense viral genomic RNA (vRNA). Each vRNA strand associates with nucleoproteins and an RNA-dependent RNA polymerase complex to ... Peterl S, Wachsmuth-Melm M, Chlanda P. Sample Preparation for Cryo-Electron Tomography of Influenza A Virus and Infected Cells. Methods Mol Biol. 2025;2890:169-184. Abstract
submitted by kickingbird at Feb, 3, 2025 from Methods Mol Biol. 2025;2890:169-184 (via https://link.springer.com/protocol/10.1007/978-1-0716-4326-6)
Influenza A virus (IAV) replication within host cells relies on tightly controlled, dynamic interactions between viral and cellular components. Yet we have a limited understanding of the viral replication ... Sousa AL, Tranfield EM. Room Temperature Transmission Electron Microscopy of Influenza A Virus Samples. Methods Mol Biol. 2025;2890:151-167. Abstract
submitted by kickingbird at Feb, 3, 2025 from Methods Mol Biol. 2025;2890:151-167 (via https://link.springer.com/protocol/10.1007/978-1-0716-4326-6)
Transmission electron microscopy is an imaging technique that visualizes the ultrastructure of samples, revealing not just the structures of interest but also the context occurring around the structures ... Lee N. Mapping Binding Sites of Nucleoprotein Within the Influenza Virus RNA Genome. Methods Mol Biol. 2025;2890:211-224. Abstract
submitted by kickingbird at Feb, 3, 2025 from Methods Mol Biol. 2025;2890:211-224 (via https://link.springer.com/protocol/10.1007/978-1-0716-4326-6)
With the advent of next-generation sequencing, a plethora of techniques have been developed to uncover nucleic acid interactions with unprecedented resolution. For example, UV-crosslinking and immunoprecipitation ... Wang X, Dai J, Yang W, Yao Y, Zhang J, Liu K, Lu X. Spray vaccination with a safe and bivalent H9N2 recombinant chimeric NDV vector vaccine elicits complete protection against NDV and H9N2 AIV challenge. Vet Res. 2025 Jan 31;56(1):24. Abstract
submitted by kickingbird at Feb, 3, 2025 from Vet Res. 2025 Jan 31;56(1):24 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
Newcastle disease virus (NDV) and H9N2 avian influenza virus (AIV) represent significant pathogenic risks to the poultry industry, leading to considerable economic losses. Vaccination is a widely used ... Luo J, Wang X, Fan X, He Y, Du X, Chen YQ, Zhao Y. A novel graph neural network based approach for influenza-like illness nowcasting: exploring the interplay of temporal, geographical, and functional spatial features. BMC Public Health. 2025 Feb 1;25(1):408. Abstract
submitted by kickingbird at Feb, 3, 2025 from BMC Public Health. 2025 Feb 1;25(1):408 (via https://bmcpublichealth.biomedcentral.com/articles/10.1186/s)
Background: Accurate and timely monitoring of influenza prevalence is essential for effective healthcare interventions. This study proposes a graph neural network (GNN)-based method to address the issue ... Cha RM, Park MJ, Baek YG, Lee YN, Jang Y, Kang YM,. Genetic characteristics and pathogenesis of clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus isolated from poultry in South Korea, 2022-2023. Virus Res. 2025 Jan 31:199541. Abstract
submitted by kickingbird at Feb, 3, 2025 from Virus Res. 2025 Jan 31:199541 (via https://pubmed.ncbi.nlm.nih.gov/39894372/)
During the 2022-2023 winter season in South Korea, a novel clade 2.3.4.4b H5N1 HPAIV was first detected in wild birds, which then subsequently caused multiple outbreaks in poultry farms and wild birds. ... Kirkpatrick Roubidoux E, Meliopoulos V, Livingston. Intraductal infection with H5N1 clade 2.3.4.4b influenza virus. J Virol. 2025 Jan 31:e0192724. Abstract
submitted by kickingbird at Feb, 1, 2025 from J Virol. 2025 Jan 31:e0192724 (via https://journals.asm.org/doi/10.1128/jvi.01927-24)
In March 2024, highly pathogenic avian influenza (HPAI) H5N1 of the clade 2.3.4.4b was detected in dairy cows in Texas and has since been detected in several other U.S. states. Virus has been detected ... Separovic L, Zhan Y, Kaweski SE, Sabaiduc S, Caraz. Interim estimates of vaccine effectiveness against influenza A(H1N1)pdm09 and A(H3N2) during a delayed influenza season, Canada, 2024/25. Euro Surveill. 2025 Jan;30(4). Abstract
submitted by kickingbird at Jan, 31, 2025 from Euro Surveill. 2025 Jan;30(4) (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
The Canadian Sentinel Practitioner Surveillance Network (SPSN) reports interim 2024/25 vaccine effectiveness (VE) against acute respiratory illness due to laboratory-confirmed influenza during a delayed ... Lee SL, Kwan MYW, Murphy C, Chan ELY, Wong JSC, Su. Influenza vaccine effectiveness against influenza-associated hospitalizations in children, Hong Kong, November 2023 to June 2024. Vaccine X. 2024 Oct 6;20:100570. Abstract
submitted by kickingbird at Jan, 31, 2025 from Vaccine X. 2024 Oct 6;20:100570 (via https://www.sciencedirect.com/science/article/pii/S259013622)
We conducted a test negative study from November 2023 to June 2024, enrolling 4,367 children hospitalized with acute respiratory illness in Hong Kong. Among the children who tested negative for influenza ... EFSA Panel on Animal Health and Animal Welfare (AH. Preparedness, prevention and control related to zoonotic avian influenza. https://doi.org/10.2903/j.efsa.2025.9191. Abstract
submitted by kickingbird at Jan, 30, 2025 from https://doi.org/10.2903/j.efsa.2025.9191 (via https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2025)
A risk assessment framework was developed to evaluate the zoonotic potential of avian influenza (AI), focusing on virus mutations linked to phenotypic traits related to mammalian adaptation identified ... European Food Safety Authority (EFSA). Avian influenza annual report 2023. https://doi.org/10.2903/j.efsa.2025.9197. Abstract
submitted by kickingbird at Jan, 30, 2025 from https://doi.org/10.2903/j.efsa.2025.9197 (via https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2025)
All European Union (EU) Member States (MSs), along with Iceland, Norway, Switzerland and the United Kingdom (Northern Ireland), conduct surveillance for avian influenza (AI) in poultry and wild birds. ... Schafers, J., Warren, C.J., Yang, J. et al. Pasteurisation temperatures effectively inactivate influenza A viruses in milk. Nat Commun 16, 1173 (2025). Abstract
submitted by kickingbird at Jan, 30, 2025 from Nat Commun 16, 1173 (2025) (via https://link.springer.com/article/10.1038/s41467-025-56406-8)
In late 2023 an H5N1 lineage of high pathogenicity avian influenza virus (HPAIV) began circulating in American dairy cattle Concerningly, high titres of virus were detected in cows’ milk, raising the concern ... Beate M. Crossley, etc.,al. In laboratory inactivation of H5N1 in raw whole milk through milk acidification: results from a pilot study. Journal of Dairy Science. Abstract
submitted by kickingbird at Jan, 30, 2025 from Journal of Dairy Science (via https://www.sciencedirect.com/science/article/pii/S002203022)
Avian Influenza virus H5N1 2.3.4.4.b has recently been detected in cattle, with milk from infected animals reported to contain a high viral load, serving as a potential source for shedding and dissemination ... Nicholas C. Morano, etc.,al. Structure of a zoonotic H5N1 hemagglutinin reveals a receptor-binding site occupied by an auto-glycan. Structure, January 2025. Abstract
submitted by kickingbird at Jan, 30, 2025 from Structure, January 2025 (via https://www.sciencedirect.com/science/article/abs/pii/S09692)
Highly pathogenic avian influenza has spilled into many mammals, most notably cows and poultry, with several dozen human breakthrough infections. Zoonotic crossovers, with hemagglutinins mutated to enhance ... Huarui Duan, etc.,al. Computational design and improvement of a broad influenza virus HA stem targeting antibody. Structure, January 2025. Abstract
submitted by kickingbird at Jan, 30, 2025 from Structure, January 2025 (via https://www.sciencedirect.com/science/article/abs/pii/S09692)
Broadly neutralizing antibodies (nAbs) are vital therapeutic tools to counteract both pandemic and seasonal influenza threats. Traditional strategies for optimizing nAbs generally rely on labor-intensive, ... Nishiyama A, Nogimori T, Masuta Y, Matsuura T, Kas. Cross-Reactive Fc-Mediated Antibody Responses to Influenza HA Stem Region in Human Sera Following Seasonal Vaccination. Vaccines. 2025; 13(2):140. Abstract
submitted by kickingbird at Jan, 30, 2025 from Vaccines. 2025; 13(2):140 (via https://www.mdpi.com/2076-393X/13/2/140)
Background: Current influenza A vaccines primarily induce neutralizing antibodies targeting the variable hemagglutinin (HA) head domain, limiting their effectiveness against diverse or emerging influenza ... Wang Z, Tian C, Zhu J, Wang S, Ao X, He Y, Chen H,. Avian influenza mRNA vaccine encoding hemagglutinin provides complete protection against divergent H5N1 viruses in specific-pathogen-free chickens. J Nanobiotechnology. 2025 Jan 29;23(1):55. Abstract
submitted by kickingbird at Jan, 30, 2025 from J Nanobiotechnology. 2025 Jan 29;23(1):55 (via https://jnanobiotechnology.biomedcentral.com/articles/10.118)
Background: The rapid mutation of avian influenza virus (AIV) poses a significant threat to both the poultry industry and public health. Herein, we have successfully developed an mRNA-LNPs candidate vaccine ... 8602 items, 20/Page, Page[11/431][|<<] [|<] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [>|] [>>|] |
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