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2024-5-4 14:46:47
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HUANG Yi-wei; LI Zi; ZHANG Hong;etc.,al. Laboratory Diagnosis and Molecular Characterization of Highly Pathogenic Avian Influenza Virus(H5N1) in Human in Hunan Province in 2005-2006. Chinese Journal of Virology.  Abstract  
submitted by kickingbird at Jan, 29, 2008 from Chinese Journal of Virology (via http://www.cnki.net)
To determine the etiologic agents of two atypical pneumonia human cases in Hunan Province in 2005-2006 and to study their pathogenic potential,the patients' respiratory tract samples and sera were collected.The ...

LIU Yan; LI Qun; HE Yi-xin;etc.,al. The Firstly Confirmed Pregnant Woman Case of Avian Influenza A(H5N1) by Etiological Research in China. Chinese Journal of Virology.  Abstract  
submitted by kickingbird at Jan, 29, 2008 from Chinese Journal of Virology (via http://www.cnki.net)
To investigate the cause of death of a pregnant woman with undefined pneumonia reported from the People's Hospital of Tongling City in Anhui Province on November 8,2005,the patient's tracheal aspirates ...

ZHAO Hong-xia; XIA Xian-zhu; Lu Ji-rong. The study on expression of CD54 and it´s receptors on the surface of peripheral blood leucocyte in HPAIV infection in mice. Chinese Journal of Laboratory Diagnosis.  Abstract  
submitted by kickingbird at Jan, 29, 2008 from Chinese Journal of Laboratory Diagnosis (via http://www.cnki.net)
Objective To study the role CD11b,CD18 and CD54 on the surface of peripheral blood leucocyte in HPAIV infection in mice.Methods 60 Kunming mice,weight is 18-20 gramma,we divide them to two groups randomly:experiment ...

KERRY PS, Willsher N, Fodor E. A cluster of conserved basic amino acids near the C-terminus of the PB1 subunit of the influenza virus RNA polymerase is involved in the regulation of viral transcription. Virology. 2008 Jan 7.  Abstract  
submitted by kickingbird at Jan, 23, 2008 from Virology. 2008 Jan 7 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
Synthesis of influenza virus mRNA by the viral RNA polymerase complex is primed by capped RNA fragments generated by endonuclease cleavage of host pre-mRNA by the polymerase subunit PB1. In previous studies, ...

Dittmann J, Stertz S, Grimm D, Steel J, García-Sas. Influenza A virus strains differ in sensitivity to the antiviral action of the Mx-GTPase. J Virol. 2008 Jan 16.  Abstract  
submitted by kickingbird at Jan, 23, 2008 from J Virol. 2008 Jan 16 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
Interferon-mediated host responses are of great importance for controlling influenza A virus infections. It is well established that the interferon-induced Mx proteins possess powerful antiviral activities ...

Lam WY, Tang JW, Yeung AC, Chiu LC, Sung JJ, Chan. Avian influenza A/HK/483/97(H5N1) NS1 protein induces apoptosis in human airway epithelial cells. J Virol. 2008 Jan 16.  Abstract  
submitted by kickingbird at Jan, 23, 2008 from J Virol. 2008 Jan 16 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
Avian H5N1 influenza virus causes a remarkably severe disease in humans, with an overall case-fatality rate of greater than 50%. Human influenza A viruses induce apoptosis in infected cells which can lead ...

Lang AS, Kelly A, Runstadler JA. Prevalence and diversity of avian influenza viruses in environmental reservoirs. J Gen Virol. 2008 Feb;89(Pt 2):509-19.  Abstract  
submitted by kickingbird at Jan, 23, 2008 from J Gen Virol. 2008 Feb;89(Pt 2):509-19 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
Little is known about the ecology and evolution of avian influenza in the natural environment, despite how these affect the potential for transmission. Most work has focused on characterizing viruses isolated ...

Jorba N, Area E, Ortín J. Oligomerization of the influenza virus polymerase complex in vivo. J Gen Virol. 2008 Feb;89(Pt 2):520-4.  Abstract  
submitted by kickingbird at Jan, 23, 2008 from J Gen Virol. 2008 Feb;89(Pt 2):520-4 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
The influenza virus polymerase is a heterotrimer formed by the PB1, PB2 and PA subunits and is responsible for virus transcription and replication. We have expressed the virus polymerase complex by co-transfection ...

YU H, Hua RH, Zhang Q, Liu TQ, et al.. Genetic evolution of swine influenza A (H3N2) viruses in China from 1970 to 2006. J Clin Microbiol. 2008 Jan 16.  Abstract  
submitted by kickingbird at Jan, 23, 2008 from J Clin Microbiol. 2008 Jan 16 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
Pigs are susceptible to both human and avian influenza viruses and have been proposed to be intermediate hosts or "mixing vessels" for the generation of pandemic influenza viruses through reassortment ...

M. Giese et al.. Experimental Infection and Natural Contact Exposure of Dogs with Avian Influenza Virus (H5N1). Emerg Infect Dis. 2008 Feb.  Full Text  
submitted by kickingbird at Jan, 22, 2008 from Emerg Infect Dis. 2008 Feb (via http://www.cdc.gov/eid/content/14/2/pdfs/07-0864.pdf)
?Contact exposure experiments of influenza virus (H5N1)–infected cats with susceptible dogs, and   infected dogs with susceptible dogs and cats, did not result in intraspecies or interspecies transmission. ...

Parmley EJ, Bastien N, Booth TF, Bowes V, Buck PA,. Wild Bird Influenza Survey, Canada, 2005. Emerg Infect Dis. 2008 Jan.  Abstract  
submitted by kickingbird at Jan, 22, 2008 from Emerg Infect Dis. 2008 Jan (via http://www.cdc.gov/EID/content/14/1/84.htm)
AbstractOf 4,268 wild ducks sampled in Canada in 2005, real-time reverse transcriptase–PCR detected influenza A matrix protein (M1) gene sequence in 37% and H5 gene sequence in 5%. Mallards accounted for ...

WHO. Update on Avian Influenza A (H5N1) Virus Infection in Humans. NEJM.  Full Text  
submitted by kickingbird at Jan, 17, 2008 from NEJM (via http://content.nejm.org/cgi/content/full/358/3/261)
The unprecedented epizootic of avian influenza A (H5N1) viruses among birds continues to cause human disease with high mortality and to pose the threat of a pandemic. This review updates a 2005 report ...

Ngunjiri JM, Sekellick MJ, Marcus PI.. Clonogenic Assay of Type A Influenza Viruses Reveals Noninfectious Cell-Killing (Apoptosis-Inducing) Particlesa. J Virol. 2008 Jan 9.  Abstract  
submitted by kickingbird at Jan, 17, 2008 from J Virol. 2008 Jan 9 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
Clonogenic (single-cell plating) assays were used to define and quantify subpopulations of two genetically closely related variants of influenza virus A/TK/OR/71 that differed primarily in the size of ...

Anwar T, Khan AU.. Identification of a casein kinase II phosphorylation domain in NS1 protein of H5N1 influenza virus.. Bioinformation. 2007 Oct 3;2(2):57-61.  Full Text  
submitted by kickingbird at Jan, 15, 2008 from Bioinformation. 2007 Oct 3;2(2):57-61 (via http://www.ncbi.nlm.nih.gov/pubmed/18188421?ordinalpos=1&ito)
Influenza virus causes febrile respiratory illness. The infection results in significant mortality, morbidity and economic disruption. In this bioinformatics study, we used the NS1 (the conserved nonstructural) ...

Liao YC, Lee MS, Ko CY, Hsiung CA.. Bioinformatics models for predicting antigenic variants of influenza A/H3N2 virus. Bioinformatics. 2008 Jan 10.  Abstract  
submitted by kickingbird at Jan, 15, 2008 from Bioinformatics. 2008 Jan 10 (via http://www.ncbi.nlm.nih.gov/pubmed/18187440?ordinalpos=3&ito)
MOTIVATION: Continual and accumulated mutations in hemagglutinin (HA) protein of influenza A virus generate novel antigenic strains that cause annual epidemics. RESULTS: We propose a model by incorporating ...

Ng SS, Li OT, Cheung TK, Peiris JM, Poon LL. Heterologous influenza vRNA segments with identical non-coding sequences stimulate viral RNA replication in trans. Virol J. 2008 Jan 11;5(1):2.  Abstract  
submitted by kickingbird at Jan, 15, 2008 from Virol J. 2008 Jan 11;5(1):2 (via http://www.ncbi.nlm.nih.gov/pubmed/18186945?ordinalpos=4&ito)
ABSTRACT: The initiation of transcription and replication of influenza A virus requires the 5' and 3' ends of vRNA. Here, the role of segment-specific non-coding sequences of influenza A virus on viral ...

Wang Q, Cheng F, Lu M, Tian X, Ma J.. Crystal Structure of Unliganded Influenza B Virus Hemagglutinin. J Virol. 2008 Jan 9.  Abstract  
submitted by kickingbird at Jan, 15, 2008 from J Virol. 2008 Jan 9 (via http://www.ncbi.nlm.nih.gov/pubmed/18184701?ordinalpos=10&it)
Here we report the crystal structure of hemagglutinin (HA) from influenza B/HK/8/73 virus determined to 2.8 A. At a sequence identity of approximately 25% to influenza A virus HAs, B/HK HA shares a similar ...

Djikeng A, Halpin RA, Kuzmickas R, Depasse J, Feld. Viral genome sequencing by random priming methods. BMC Genomics. 2008 Jan 7;9(1):5.  Full Text  
submitted by kickingbird at Jan, 11, 2008 from BMC Genomics. 2008 Jan 7;9(1):5 (via http://www.ncbi.nlm.nih.gov/pubmed/18179705?ordinalpos=10&it)
Most emerging health threats are of zoonotic origin. For the overwhelming majority, their causative agents are RNA viruses which include but are not limited to HIV, Influenza, SARS, Ebola, Dengue, and ...

Mazur I, Anhlan D, Mitzner D, Wixler L, Schubert U. The proapoptotic influenza A virus protein PB1-F2 regulates viral polymerase activity by interaction with the PB1 protein. Cell Microbiol. 2008 Jan 7.  Abstract  
submitted by kickingbird at Jan, 11, 2008 from Cell Microbiol. 2008 Jan 7 (via http://www.ncbi.nlm.nih.gov/pubmed/18182088?ordinalpos=4&ito)
The 11(th) influenza A virus protein PB1-F2 was previously shown to enhance apoptosis in response to cytotoxic stimuli. The 87 amino acid protein that is encoded by an alternative reading frame of the ...

Aarthi Chandrasekaran, etc.,al. Glycan topology determines human adaptation of avian H5N1 virus hemagglutinin. Nature Biotechnology 26, 107 - 113 (2007).  Abstract  
submitted by kickingbird at Jan, 9, 2008 from Nature Biotechnology 26, 107 - 113 (2007) (via http://www.nature.com/nbt/journal/v26/n1/abs/nbt1375.html)
A switch in specificity of avian influenza A viruses' hemagglutinin (HA) from avian-like (2-3 sialylated glycans) to human-like (2-6 sialylated glycans) receptors is believed to be associated with their ...

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