Zu S, Xue Q, He Z, et al. Duck PIAS2 Promotes H5N1 Avian Influenza Virus Replication Through Its SUMO E3 Ligase Activity. Front Microbiol. 2020;11:1246. Abstract submitted by kickingbird at Jun, 30, 2020 from Front Microbiol. 2020;11:1246 (via https://pubmed.ncbi.nlm.nih.gov/32595623/) The protein inhibitor of the activated STAT2 (PIAS2) has been implicated in many cellular processes and can also regulate viral replication in mammals. However, the role of PIAS2 in the highly pathogenic ... McCuen MM, Pitesky ME, Buler JJ, et al. A Comparison of Amplification Methods to Detect Avian Influenza Viruses in California Wetlands Targeted via Remote Sensing of Waterfowl. Transbound Emerg Dis. 2020;10.1111/tbed.13612. Abstract submitted by kickingbird at Jun, 30, 2020 from Transbound Emerg Dis. 2020;10.1111/tbed.13612 (via https://pubmed.ncbi.nlm.nih.gov/32592444/) Migratory waterfowl, including geese and ducks, are indicated as the primary reservoir of avian influenza viruses (AIv) which can be subsequently spread to commercial poultry. The US Department of Agriculture's ... Zhang Y, Zhang HX, Zheng Q. In Silico Study of Membrane Lipid Composition Regulating Conformation and Hydration of Influenza Virus B M2 Channel. J Chem Inf Model. 2020;10.1021/acs.jcim.0c00329. Abstract submitted by kickingbird at Jun, 27, 2020 from J Chem Inf Model. 2020;10.1021/acs.jcim.0c00329 (via https://pubmed.ncbi.nlm.nih.gov/32589410/) The proton conduction of transmembrane influenza virus B M2 (BM2) proton channel is possibly mediated by the membrane environment, but the detailed molecular mechanism is challenging to determine. In this ... Zhou X, Gao L, Wang Y, et al. Geographical Variation in the Risk of H7N9 Human Infections in China: Implications for Risk-Based Surveillance. Sci Rep. 2020;10(1):10372.. Abstract submitted by kickingbird at Jun, 27, 2020 from Sci Rep. 2020;10(1):10372. (via https://pubmed.ncbi.nlm.nih.gov/32587266/) The influenza A (H7N9) subtype remains a public health problem in China affecting individuals in contact with live poultry, particularly at live bird markets. Despite enhanced surveillance and biosecurity ... Endo M, Tanishima M, Ibaragi K, et al. Clinical Phase II and III Studies of an AS03-adjuvanted H5N1 Influenza Vaccine Produced in an EB66 ? Cell Culture Platform. Influenza Other Respir Viruses. 2020;10.1111/irv.. Abstract submitted by kickingbird at Jun, 26, 2020 from Influenza Other Respir Viruses. 2020;10.1111/irv. (via https://pubmed.ncbi.nlm.nih.gov/32579785/) Background: We have developed an AS03-adjuvanted H5N1 influenza vaccine produced in an EB66? cell culture platform (KD-295). Objectives: In accordance with Japanese guidelines for development of pandemic ... Hao W, Wang L, Li S. FKBP5 Regulates RIG-I-Mediated NF-κB Activation and Influenza A Virus Infection. Viruses. 2020;12(6):E672. Abstract submitted by kickingbird at Jun, 26, 2020 from Viruses. 2020;12(6):E672 (via https://pubmed.ncbi.nlm.nih.gov/32580383/) Influenza A virus (IAV) is a highly transmissible respiratory pathogen and is a constant threat to global health with considerable economic and social impact. Influenza viral RNA is sensed by host pattern ... Everest H, Hill SC, Daines R, et al. The Evolution, Spread and Global Threat of H6Nx Avian Influenza Viruses. Viruses. 2020;12(6):E673. Abstract submitted by kickingbird at Jun, 26, 2020 from Viruses. 2020;12(6):E673 (via https://pubmed.ncbi.nlm.nih.gov/32580412/) Avian influenza viruses of the subtype H6Nx are being detected globally with increasing frequency. Some H6Nx lineages are becoming enzootic in Asian poultry and sporadic incursions into European poultry ... Giotis ES. Inferring the Urban Transmission Potential of Bat Influenza Viruses. Front Cell Infect Microbiol. 2020;10:264. Abstract submitted by kickingbird at Jun, 26, 2020 from Front Cell Infect Microbiol. 2020;10:264 (via https://pubmed.ncbi.nlm.nih.gov/32582567/) Bats are considered natural reservoirs of various, potentially zoonotic viruses, exemplified by the influenza A-like viruses H17N10 and H18N11 in asymptomatic Neotropical bats. These influenza viruses ... Xia J, Adam DC, Moa A, et al. Comparative Epidemiology, Phylogenetics, and Transmission Patterns of Severe Influenza A/H3N2 in Australia From 2003 to 2017. Influenza Other Respir Viruses. 2020;10.1111/irv.. Abstract submitted by kickingbird at Jun, 25, 2020 from Influenza Other Respir Viruses. 2020;10.1111/irv. (via https://pubmed.ncbi.nlm.nih.gov/32558378/) Background: Over the last two decades, Australia has experienced four severe influenza seasons caused by a predominance of influenza A (A/H3N2): 2003, 2007, 2012, and 2017. Methods: We compared the epidemiology, ... Islam SS, Akwar H, Hossain MM, et al. Qualitative Risk Assessment of Transmission Pathways of Highly Pathogenic Avian Influenza (HPAI) Virus at Live Poultry Markets in Dhaka City, Bangladesh. Zoonoses Public Health. 2020;10.1111/zph.12746. Abstract submitted by kickingbird at Jun, 25, 2020 from Zoonoses Public Health. 2020;10.1111/zph.12746 (via https://pubmed.ncbi.nlm.nih.gov/32558220/) Analysis of environmental samples obtained from the Live Poultry Markets (LPMs) of Dhaka City, Bangladesh, has revealed that the highest degree of prevalence of highly pathogenic avian influenza A (HPAI, ... Lin RJ, Huang CH, Liu PC, et al. Zinc Finger Protein ZFP36L1 Inhibits Influenza A Virus Through Translational Repression by Targeting HA, M and NS RNA Transcripts. Nucleic Acids Res. 2020;gkaa458. Abstract submitted by kickingbird at Jun, 25, 2020 from Nucleic Acids Res. 2020;gkaa458 (via https://pubmed.ncbi.nlm.nih.gov/32556261/) ZFP36L1, a CCCH-type zinc finger protein, is an RNA-binding protein that participates in controlling cellular mRNA abundance and turnover by posttranscriptional regulation. Here, we demonstrated that ZFP36L1 ... Cheng KJG, Rivera AS, Lam HY, et al. Influenza-associated Excess Mortality in the Philippines, 2006-2015. PLoS One. 2020;15(6):e0234715. Abstract submitted by kickingbird at Jun, 25, 2020 from PLoS One. 2020;15(6):e0234715 (via https://pubmed.ncbi.nlm.nih.gov/32555618/) Influenza-associated mortality has not been quantified in the Philippines. Here, we constructed multiple negative binomial regression models to estimate the overall and age-specific excess mortality rates ... Wu NC, Thompson AJ, Lee JM, et al. Different Genetic Barriers for Resistance to HA Stem Antibodies in Influenza H3 and H1 Viruses. Science. 2020;368(6497):1335-1340. Abstract submitted by kickingbird at Jun, 25, 2020 from Science. 2020;368(6497):1335-1340 (via https://pubmed.ncbi.nlm.nih.gov/32554590/) The discovery and characterization of broadly neutralizing human antibodies (bnAbs) to the highly conserved stem region of influenza hemagglutinin (HA) have contributed to considerations of a universal ... Qin Z, Qu X, Lei L, Xu L, Pan Z. Y-Box-Binding Protein 3 (YBX3) Restricts Influenza A Virus by Interacting With Viral Ribonucleoprotein Complex and Imparing Its Function. J Gen Virol. 2020;101(4):385-398.. Abstract submitted by kickingbird at Jun, 25, 2020 from J Gen Virol. 2020;101(4):385-398. (via https://pubmed.ncbi.nlm.nih.gov/32553055/) The influenza A virus (IAV) ribonucleoprotein (vRNP) complex consists of polymerase subunits, nucleoprotein (NP) and viral RNA and is responsible for RNA transcription and replication. Interactions between ... Alvarez IJ, Fort M, Pasucci J, et al. Seroprevalence of Influenza D Virus in Bulls in Argentina. J Vet Diagn Invest. 2020;1040638720934056.. Abstract submitted by kickingbird at Jun, 25, 2020 from J Vet Diagn Invest. 2020;1040638720934056. (via https://pubmed.ncbi.nlm.nih.gov/32552516/) Influenza D virus (IDV) is considered a new agent involved in bovine respiratory disease (BRD). Based on seroprevalence studies or isolation from clinical samples, this virus has been detected on several ... Sun N, Jiang L, Ye M, et al. TRIM35 Mediates Protection Against Influenza Infection by Activating TRAF3 and Degrading Viral PB2. Protein Cell. 2020;10.1007/s13238-020-00734-6. Abstract submitted by kickingbird at Jun, 25, 2020 from Protein Cell. 2020;10.1007/s13238-020-00734-6 (via https://pubmed.ncbi.nlm.nih.gov/32562145/) Tripartite motif (TRIM) family proteins are important effectors of innate immunity against viral infections. Here we identified TRIM35 as a regulator of TRAF3 activation. Deficiency in or inhibition of ... Tran QA, Le Thi H, Thi Thanh Le X, To Long T. The Presence of Poultry Influenza Strains in Two Live Bird Markets Near the East-West Boundary of Vietnam. Biomed Res Int. 2020;2020:1487651. Abstract submitted by kickingbird at Jun, 25, 2020 from Biomed Res Int. 2020;2020:1487651 (via https://pubmed.ncbi.nlm.nih.gov/32566655/) The spread of avian influenza virus among Asian countries is becoming a concern after influenza epidemics in recent years. This study is aimed at identifying the subtypes of avian influenza viruses collected ... ?wi?toń E, Fusaro A, Shittu I, et al. Sub-Saharan Africa and Eurasia Ancestry of Reassortant Highly Pathogenic Avian Influenza A(H5N8) Virus, Europe, December 2019. Emerg Infect Dis. 2020;26(7):1557-1561. Abstract submitted by kickingbird at Jun, 25, 2020 from Emerg Infect Dis. 2020;26(7):1557-1561 (via https://pubmed.ncbi.nlm.nih.gov/32568059/) We report detection of a highly pathogenic avian influenza A(H5N8) clade 2.3.4.4b virus in Europe. This virus was generated by reassortment between H5N8 subtype virus from sub-Saharan Africa and low pathogenicity ... Podshivalov DD, Kirilin EM, Konnov SI, ?vedas VK. Structural Organization and Dynamic Characteristics of the Binding Site for Conformational Rearrangement Inhibitors in Hemagglutinins From H3N2 and H7N9 Influenza Viruses. Biochemistry (Mosc). 2020;85(4):499-506. Abstract submitted by kickingbird at Jun, 25, 2020 from Biochemistry (Mosc). 2020;85(4):499-506 (via https://pubmed.ncbi.nlm.nih.gov/32569557/) Computer models of hemagglutinins from the H3N2 and H7N9 influenza viruses were developed to study structural organization and dynamic characteristics of the binding site for the conformational rearrangement ... Bhat S, Bialy D, Sealy JE, Sadeyen JR, Chang P, Iq. A Ligation and Restriction Enzyme Independent Cloning Technique: An Alternative to Conventional Methods for Cloning Hard-To-Clone Gene Segments in the Influenza Reverse Genetics System. Virol J. 2020;17(1):82. Abstract submitted by kickingbird at Jun, 25, 2020 from Virol J. 2020;17(1):82 (via https://pubmed.ncbi.nlm.nih.gov/32576218/) Background: Reverse genetics is used in many laboratories around the world and enables the creation of tailor-made influenza viruses with a desired genotype or phenotype. 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