Mehaffey MR, Lee J, Jung J, et al. Mapping a Conformational Epitope of Hemagglutinin A Using Native Mass Spectrometry and Ultraviolet Photodissociation. Anal Chem. 2020;92(17):11869-11878. Abstract
submitted by kickingbird at Sep, 1, 2020 from Anal Chem. 2020;92(17):11869-11878 (via https://pubs.acs.org/doi/10.1021/acs.analchem.0c02237)
As the importance of effective vaccines and the role of protein therapeutics in the drug industry continue to expand, alternative strategies to characterize protein complexes are needed. Mass spectrometry ... Li BD, He J, Li HY, et al. Analysis on genetic characteristics of H9N2 avian influenza virus isolated from human infection and external environment in Gansu province. Zhonghua Liu Xing Bing Xue Za Zhi. 2020;41(8):1345. Abstract
submitted by kickingbird at Sep, 1, 2020 from Zhonghua Liu Xing Bing Xue Za Zhi. 2020;41(8):1345 (via https://pubmed.ncbi.nlm.nih.gov/32867448/)
Objective: To analyze the genomic characteristics of human infection with H9N2 avian influenza virus in Gansu province. Methods: The etiological analysis was conducted for human infection with H9N2 avian ... Wacquiez A, Coste F, Kut E, et al. Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1. Viruses. 2020;12(9):E947. Abstract
submitted by kickingbird at Sep, 1, 2020 from Viruses. 2020;12(9):E947 (via https://www.mdpi.com/1999-4915/12/9/947)
The non-structural protein NS1 of influenza A viruses is an RNA-binding protein of which its activities in the infected cell contribute to the success of the viral cycle, notably through interferon antagonism. ... Turner JS, Zhou JQ, Han J, et al. Human germinal centres engage memory and naive B cells after influenza vaccination. Nature. 2020;10.1038/s41586-020-2711-0. Abstract
submitted by kickingbird at Sep, 1, 2020 from Nature. 2020;10.1038/s41586-020-2711-0 (via https://www.nature.com/articles/s41586-020-2711-0)
Influenza viruses remain a major public health threat. Seasonal influenza vaccination in humans primarily stimulates pre-existing memory B cells, leading to a transient wave of circulating antibody-secreting ... Percopo CM, Ma M, Mai E, et al. Alternaria alternata Accelerates Loss of Alveolar Macrophages and Promotes Lethal Influenza A Infection. Viruses. 2020;12(9):E946. Abstract
submitted by kickingbird at Sep, 1, 2020 from Viruses. 2020;12(9):E946 (via https://pubmed.ncbi.nlm.nih.gov/32867061/)
Chronic inhalation of fungi and fungal components has been linked to the development of respiratory disorders, although their role with respect to the pathogenesis of acute respiratory virus infection ... Du W, Wolfert MA, Peeters B, et al. Mutation of the second sialic acid-binding site of influenza A virus neuraminidase drives compensatory mutations in hemagglutinin. PLoS Pathog. 2020;16(8):e1008816. Abstract
submitted by kickingbird at Aug, 31, 2020 from PLoS Pathog. 2020;16(8):e1008816 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Influenza A viruses (IAVs) cause seasonal epidemics and occasional pandemics. Most pandemics occurred upon adaptation of avian IAVs to humans. This adaptation includes a hallmark receptor-binding specificity ... Ilyushina NA, Lee N, Lugovtsev VY, Kan A, Bovin NV. Adaptation of influenza B virus by serial passage in human airway epithelial cells. Virology. 2020;549:68-76. Abstract
submitted by kickingbird at Aug, 31, 2020 from Virology. 2020;549:68-76 (via https://pubmed.ncbi.nlm.nih.gov/32853848/)
Influenza B viruses cause seasonal epidemics and are a considerable burden to public health. To understand their adaptation capability, we examined the genetic changes that occurred following 15 serial ... ?wi?toń E, Tarasiuk K, ?mietanka K. Low pathogenic avian influenza virus isolates with different levels of defective genome segments vary in pathogenicity and transmission efficiency. Vet Res. 2020;51(1):108. Abstract
submitted by kickingbird at Aug, 31, 2020 from Vet Res. 2020;51(1):108 (via https://pubmed.ncbi.nlm.nih.gov/32859269/)
Defective interfering particles (DIPs) of influenza virus are generated through incorporation of highly truncated forms of genome segments, mostly those coding polymerase complex proteins (PB2, PB1, PA). ... Jerry C, Stallknecht D, Leyson C, et al. Recombinant hemagglutinin glycoproteins provide insight into binding to host cells by H5 influenza viruses in wild and domestic birds. irology. 2020;550:8-20. Abstract
submitted by kickingbird at Aug, 31, 2020 from irology. 2020;550:8-20 (via https://pubmed.ncbi.nlm.nih.gov/32861143/)
Clade 2.3.4.4, H5 subtype highly pathogenic avian influenza viruses (HPAIVs) have caused devastating effects across wild and domestic bird populations. We investigated differences in the intensity and ... Seekings AH, Howard WA, Nu?éz A, et al. The Emergence of H7N7 Highly Pathogenic Avian Influenza Virus from Low Pathogenicity Avian Influenza Virus Using an in ovo Embryo Culture Model. Viruses. 2020;12(9):E920. Abstract
submitted by kickingbird at Aug, 26, 2020 from Viruses. 2020;12(9):E920 (via https://www.mdpi.com/1999-4915/12/9/920)
Outbreaks of highly pathogenic avian influenza virus (HPAIV) often result in the infection of millions of poultry, causing up to 100% mortality. HPAIV has been shown to emerge from low pathogenicity avian ... Tran V, Ledwith MP, Thamamongood T, et al. Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs. Nat Microbiol. 2020;10.1038/s41564-020-0778-x. Abstract
submitted by kickingbird at Aug, 26, 2020 from Nat Microbiol. 2020;10.1038/s41564-020-0778-x (via https://www.nature.com/articles/s41564-020-0778-x)
Cells infected by influenza virus mount a large-scale antiviral response and most cells ultimately initiate cell-death pathways in an attempt to suppress viral replication. We performed a CRISPR-Cas9-knockout ... Lou J, Zhao S, Cao L, et al. Predicting the dominant influenza A serotype by quantifying mutation activities. Int J Infect Dis. 2020;S1201-9712(20)30682-2. Abstract
submitted by kickingbird at Aug, 26, 2020 from Int J Infect Dis. 2020;S1201-9712(20)30682-2 (via https://pubmed.ncbi.nlm.nih.gov/32841687/)
Objectives: Characterizing and predicting the evolutionary process of influenza, which remains challenging, are of importance in capturing the patterns of influenza activities and the development of prevention ... Xu H, Qian J, Song Y, Ming D. The adaptability of H9N2 avian influenza A virus to humans: A comparative docking simulation study. Biochem Biophys Res Commun. 2020;529(4):963-969. Abstract
submitted by kickingbird at Aug, 25, 2020 from Biochem Biophys Res Commun. 2020;529(4):963-969 (via https://www.sciencedirect.com/science/article/abs/pii/S00062)
Influenza A virus, the H9N2 subtype, is an avian influenza virus that has long been circulating in the worldwide poultry industry and is occasionally found to be transmissible to humans. Evidence from ... Gomaa MR, El Rifay AS, Abu Zeid D, et al. Incidence and Seroprevalence of Avian Influenza in a Cohort of Backyard Poultry Growers, Egypt, August 2015-March 2019. Emerg Infect Dis. 2020;26(9):2129-2136. Abstract
submitted by kickingbird at Aug, 25, 2020 from Emerg Infect Dis. 2020;26(9):2129-2136 (via https://wwwnc.cdc.gov/eid/article/26/9/20-0266_article.htm)
Currently enzootic avian influenza H5N1, H9N2, and H5N8 viruses were introduced into poultry in Egypt in 2006, 2011, and 2016, respectively. Infections with H5N1 and H9N2 were reported among poultry-exposed ... Vandoorn E, Leroux-Roels I, Leroux-Roels G, Parys. Detection of H1 Swine Influenza A Virus Antibodies in Human Serum Samples by Age Group. Emerg Infect Dis. 2020;26(9):2118-2128. Abstract
submitted by kickingbird at Aug, 25, 2020 from Emerg Infect Dis. 2020;26(9):2118-2128 (via https://wwwnc.cdc.gov/eid/article/26/9/19-1796_article.htm)
Most H1 influenza A viruses (IAVs) of swine are derived from past human viruses. As human population immunity against these IAVs gradually decreases, the risk of reintroduction to humans increases. We ... Li H, Li Q, Li B, et al. Continuous Reassortment of Clade 2.3.4.4 H5N6 Highly Pathogenetic Avian Influenza Viruses Demonstrating High Risk to Public Health. Pathogens. 2020;9(8):E670. Abstract
submitted by kickingbird at Aug, 25, 2020 from Pathogens. 2020;9(8):E670 (via https://www.mdpi.com/2076-0817/9/8/670)
Since it firstly emerged in China in 2013, clade 2.3.4.4 H5N6 highly pathogenic avian influenza viruses (HPAIVs) has rapidly replaced predominant H5N1 to become the dominant H5 subtype in China, especially ... Gu J, Gu M, Yan Y, et al. Detection of PB2 627K mutation in two highly pathogenic isolates of the H7N9 subtype influenza A virus from chickens in northern China. J Infect. 2020;S0163-4453(20)30558-2. Abstract
submitted by kickingbird at Aug, 25, 2020 from J Infect. 2020;S0163-4453(20)30558-2 (via https://pubmed.ncbi.nlm.nih.gov/32828821/)
PB2 E627K mutation of influenza A virus has been considered relevant to increased mammalian virulence and adaptation. In H7N9, the substitution is naturally confined to most human isolates and few low ... Hopken MW, Piaggio AJ, Pabilonia KL, et al. Population genomic transformations induced by isolation of wild bird avian influenza viruses (Orthomyxoviridae) in embryonated chicken eggs. Infect Genet Evol. 2020;104505. Abstract
submitted by kickingbird at Aug, 25, 2020 from Infect Genet Evol. 2020;104505 (via https://pubmed.ncbi.nlm.nih.gov/32827730/)
Isolation and cultivation of wild-type viruses in model organism cells or tissues is standard practice in virology. Oftentimes, the virus host species is distantly related to the species from which the ... Nilsson K, Abdurahman S, Schwartz S. Influenza virus natural sequence heterogeneity in segment 8 affects interactions with cellular RNA-binding proteins and splicing efficiency. Virology. 2020;549:39-50. Abstract
submitted by kickingbird at Aug, 25, 2020 from Virology. 2020;549:39-50 (via https://pubmed.ncbi.nlm.nih.gov/32829114/)
Segment 8 mRNAs of influenza virus A/Brevig Misson/1918/1 (H1N1) are poorly spliced compared to segment 8 mRNAs of influenza virus A/Netherlands/178/95 (H3N2). Using oligonucleotide-mediated protein pull ... Asadi S, Gaaloul Ben Hnia N, Barre RS, Wexler AS,. Influenza A virus is transmissible via aerosolized fomites. Nat Commun. 2020;11(1):4062.. Abstract
submitted by kickingbird at Aug, 21, 2020 from Nat Commun. 2020;11(1):4062. (via https://www.nature.com/articles/s41467-020-17888-w)
Influenza viruses are presumed, but not conclusively known, to spread among humans by several possible routes. We provide evidence of a mode of transmission seldom considered for influenza: airborne virus ... 8128 items, 20/Page, Page[144/407][|<<] [|<] [141] [142] [143] [144] [145] [146] [147] [148] [149] [150] [>|] [>>|] |
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