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2024-11-22 22:09:38
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Islam A, Hossain ME, Amin E, Islam S, Islam M, Say. Epidemiology and phylodynamics of multiple clades of H5N1 circulating in domestic duck farms in different production systems in Bangladesh. Front Public Health. 2023 Jul 6;11:1168613.  Abstract  
submitted by kickingbird at Jul, 25, 2023 from Front Public Health. 2023 Jul 6;11:1168613 (via https://www.frontiersin.org/articles/10.3389/fpubh.2023.1168)
Waterfowl are considered to be natural reservoirs of the avian influenza virus (AIV). However, the dynamics of transmission and evolutionary patterns of AIV and its subtypes within duck farms in Bangladesh ...

Verdier V, Lilienthal F, Desvergez A, Gazaille V,. Severe forms of influenza infections admitted in intensive care units: Analysis of mortality factors. Influenza Other Respir Viruses. 2023 Jul 21;17(7):.  Abstract  
submitted by kickingbird at Jul, 25, 2023 from Influenza Other Respir Viruses. 2023 Jul 21;17(7): (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13168)
Background: The severe forms of influenza infection requiring intensive care unit (ICU) admission remain a medical challenge due to its high mortality. New H1N1 strains were hypothesized to increase mortality. ...

Liang W, Lv H, Chen C, Sun Y, Hui DS, Mok CKP. Lack of neutralizing antibodies against influenza A viruses in adults during the 2022/2023 winter season - a serological study using retrospective samples collected in Hong Kong. Int J Infect Dis. 2023 Jul 20:S1201-9712(23)00659-.  Abstract  
submitted by kickingbird at Jul, 23, 2023 from Int J Infect Dis. 2023 Jul 20:S1201-9712(23)00659- (via https://www.ijidonline.com/article/S1201-9712(23)00659-8/ful)
Background: Seasonal influenza infection cases decline significantly in Hong Kong since the COVID-19 pandemic has begun in 2020. This also reduced the opportunities of reinducing influenza-specific antibodies ...

Zhang J, Li Q, Zhu R, Xu S, Wang S, Shi H, Liu X. Loss of amino acids 67-76 in the neuraminidase protein under antibody selection pressure alters the tropism, transmissibility and innate immune response of H9N2 avian influenza virus in chickens. Vet Microbiol. 2023 Jul 17;284:109832.  Abstract  
submitted by kickingbird at Jul, 22, 2023 from Vet Microbiol. 2023 Jul 17;284:109832 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
H9N2 virus has become the most widespread subtype of avian influenza in Chinese poultry. Although many studies have been published on this disease, the pathogenesis of the H9N2 virus remains to be fully ...

Spruit CM, Sweet IR, Maliepaard JCL, Bestebroer T,. Contemporary human H3N2 influenza a viruses require a low threshold of suitable glycan receptors for efficient infection. Glycobiology. 2023 Jul 20:cwad060.  Abstract  
submitted by kickingbird at Jul, 21, 2023 from Glycobiology. 2023 Jul 20:cwad060 (via https://academic.oup.com/glycob/advance-article/doi/10.1093/)
Recent human H3N2 influenza A viruses (IAV) have evolved to employ elongated glycans terminating in α2,6-linked sialic acid as their receptors. These glycans are displayed in low abundancies by (humanized) ...

Liu L, Chen G, Huang S, Wen F. Receptor Binding Properties of Neuraminidase for influenza A virus: An Overview of Recent Research Advances. Virulence. 2023 Dec;14(1):2235459.  Abstract  
submitted by kickingbird at Jul, 21, 2023 from Virulence. 2023 Dec;14(1):2235459 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2023.2)
Influenza A viruses (IAVs) pose a serious risk to both human and animal health. IAVs' receptor binding characteristics account for a major portion of their host range and tissue tropism. While the function ...

El Sahly HM, Yildirim I, Frey SE, Winokur P, Jacks. Safety and Immunogenicity of a Delayed Heterologous Avian Influenza A(H7N9) Vaccine Boost Following Different Priming Regimens: A Randomized Clinical Trial. J Infect Dis. 2023 Jul 19:jiad276.  Abstract  
submitted by kickingbird at Jul, 20, 2023 from J Infect Dis. 2023 Jul 19:jiad276 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
Background: Influenza A (H7N9) has caused multiple disease waves with evidence of strain diversification. Optimal influenza A (H7N9) prime-boost vaccine strategies are unknown.Methods: We recruited participants ...

Liu M, Bakker AS, Narimatsu Y, van Kuppeveld FJM,. H3N2 influenza A virus gradually adapts to human-type receptor binding and entry specificity after the start of the 1968 pandemic. Proc Natl Acad Sci U S A. 2023 Aug;120(31):e230499.  Abstract  
submitted by kickingbird at Jul, 20, 2023 from Proc Natl Acad Sci U S A. 2023 Aug;120(31):e230499 (via https://www.pnas.org/doi/10.1073/pnas.2304992120)
To become established upon zoonotic transfer, influenza A viruses (IAV) need to switch binding from "avian-type" α2-3-linked sialic acid receptors (2-3Sia) to "human-type" Siaα2-6-linked sialic acid receptors ...

Noh EB, Heo GB, Lee KN, Kang YM, An SH, Kim NY, Le. Subtype specific virus enrichement with immunomagnetic separation method followed by NGS unravels the mixture of H5 and H9 avian influenza virus. J Virol Methods. 2023 Jul 17:114773.  Abstract  
submitted by kickingbird at Jul, 20, 2023 from J Virol Methods. 2023 Jul 17:114773 (via https://www.sciencedirect.com/science/article/abs/pii/S01660)
Wild bird avian influenza virus (AIV) surveillance is important for the early detection of highly pathogenic AIVs and for providing early warnings to the poultry industry and veterinary services to implement ...

Waqas FH, Shehata M, Elgaher WAM, Lacour A, Kurmas. NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner. PLoS Pathog. 2023 Jul 17;19(7):e1011506.  Abstract  
submitted by kickingbird at Jul, 18, 2023 from PLoS Pathog. 2023 Jul 17;19(7):e1011506 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
In addition to antioxidative and anti-inflammatory properties, activators of the cytoprotective nuclear factor erythroid-2-like-2 (NRF2) signaling pathway have antiviral effects, but the underlying antiviral ...

Kang M, Lin F, Jiang Z, Tan X, Lin X, Liang Z, Xia. The impact of pre-existing influenza antibodies and inflammatory status on the influenza vaccine responses in older adults. Influenza Other Respir Viruses. 2023 Jul 12;17(7):.  Abstract  
submitted by kickingbird at Jul, 17, 2023 from Influenza Other Respir Viruses. 2023 Jul 12;17(7): (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13172)
Age-associated immune changes and pre-existing influenza immunity are hypothesized to reduce influenza vaccine effectiveness in older adults, although the contribution of each factor is unknown. Here, ...

Sun L, Kong H, Yu M, Zhang Z, Zhang H, Na L, Qu Y,. The SUMO-interacting motif in NS2 promotes adaptation of avian influenza virus to mammals. Sci Adv. 2023 Jul 14;9(28):eadg5175.  Abstract  
submitted by kickingbird at Jul, 14, 2023 from Sci Adv. 2023 Jul 14;9(28):eadg5175 (via https://www.science.org/doi/10.1126/sciadv.adg5175)
Species differences in the host factor ANP32A/B result in the restriction of avian influenza virus polymerase (vPol) in mammalian cells. Efficient replication of avian influenza viruses in mammalian cells ...

Kleinehr J, Sch?fb?nker M, Daniel K, Günl F, Moham. Glycolytic interference blocks influenza A virus propagation by impairing viral polymerase-driven synthesis of genomic vRNA. PLoS Pathog. 2023 Jul 13;19(7):e1010986.  Abstract  
submitted by kickingbird at Jul, 14, 2023 from PLoS Pathog. 2023 Jul 13;19(7):e1010986 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Influenza A virus (IAV), like any other virus, provokes considerable modifications of its host cell's metabolism. This includes a substantial increase in the uptake as well as the metabolization of glucose. ...

Herfst S, Begeman L, Spronken MI, Poen MJ, Eggink. A Dutch highly pathogenic H5N6 avian influenza virus showed remarkable tropism for extra-respiratory organs and caused severe disease but was not transmissible via air in the ferret model. mSphere. 2023 Jul 10:e0020023.  Abstract  
submitted by kickingbird at Jul, 11, 2023 from mSphere. 2023 Jul 10:e0020023 (via https://journals.asm.org/doi/10.1128/msphere.00200-23)
Continued circulation of A/H5N1 influenza viruses of the A/goose/Guangdong/1/96 lineage in poultry has resulted in the diversification in multiple genetic and antigenic clades. Since 2009, clade 2.3.4.4 ...

Olajide OM, Osman MK, Robert J, Kessler S, Toews L. Evolutionarily conserved amino acids in MHC-II mediate bat influenza A virus entry into human cells. PLoS Biol. 2023 Jul 6;21(7):e3002182.  Abstract  
submitted by kickingbird at Jul, 7, 2023 from PLoS Biol. 2023 Jul 6;21(7):e3002182 (via https://journals.plos.org/plosbiology/article?id=10.1371/jou)
The viral hemagglutinins of conventional influenza A viruses (IAVs) bind to sialylated glycans on host cell surfaces for attachment and subsequent infection. In contrast, hemagglutinins of bat-derived ...

Li H, Dong W, Wang J, Yu D, Qian D, Yue L, Jiu Y,. The global epidemic trend analysis of influenza type B drug resistance sites from 2006 to 2018. J Infect Dev Ctries. 2023 Jun 30;17(6):868-873.  Abstract  
submitted by kickingbird at Jul, 6, 2023 from J Infect Dev Ctries. 2023 Jun 30;17(6):868-873 (via https://www.jidc.org/index.php/journal/article/view/17410)
Introduction: Influenza is a severe respiratory viral infection that causes significant morbidity and mortality, due to annual epidemics and unpredictable pandemics. With the extensive use of neuraminidase ...

He Z, Wang X, Lin Y, Feng S, Huang X, Zhao L, Zhan. Genetic characteristics of waterfowl-origin H5N6 highly pathogenic avian influenza viruses and their pathogenesis in ducks and chickens. Front Microbiol. 2023 Jun 15;14:1211355.  Abstract  
submitted by kickingbird at Jul, 6, 2023 from Front Microbiol. 2023 Jun 15;14:1211355 (via https://www.frontiersin.org/articles/10.3389/fmicb.2023.1211)
Waterfowl, such as ducks, are natural hosts for avian influenza viruses (AIVs) and act as a bridge for transmitting the virus to humans or susceptible chickens. Since 2013, chickens and ducks have been ...

Zhu W, Chen Q, Xu X, Wei H, Tan M, Yang L, Zou S,. Biological features of human influenza A(H3N8) viruses in China. Zhu W, Chen Q, Xu X, Wei H, Tan M, Yang L, Zou S,.  Abstract  
submitted by kickingbird at Jul, 6, 2023 from Zhu W, Chen Q, Xu X, Wei H, Tan M, Yang L, Zou S, (via https://onlinelibrary.wiley.com/doi/10.1002/jmv.28912)
Influenza A(H3N8) viruses first emerged in humans in 2022, but their public health risk has not been evaluated. Here, we systematically investigated the biological features of avian and human isolated ...

Yang H, Dong Y, Bian Y, Huo C, Zhu C, Qin T, Chen. The synergistic effect of residues 32T and 550L in the PA protein of H5 subtype avian influenza virus contributes to viral pathogenicity in mice. PLoS Pathog. 2023 Jul 3;19(7):e1011489.  Abstract  
submitted by kickingbird at Jul, 4, 2023 from PLoS Pathog. 2023 Jul 3;19(7):e1011489 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The avian influenza virus (AIV) PA protein contributes to viral replication and pathogenicity; however, its interaction with innate immunity is not well understood. Here, we report that the H5 subtype ...

Park J, Song CS, Chung DH, Choi S, Kwon J, Youk S,. Chimeric H5 influenza virus-like particle vaccine elicits broader cross-clade antibody responses in chickens than in ducks. Front Vet Sci. 2023 Jun 15;10:1158233.  Abstract  
submitted by kickingbird at Jul, 4, 2023 from Front Vet Sci. 2023 Jun 15;10:1158233 (via https://www.frontiersin.org/articles/10.3389/fvets.2023.1158)
Eurasian-lineage highly pathogenic avian influenza (HPAI) H5 viruses have spread throughout Asia, the Middle East, Europe, Africa, and most recently, North and South America. These viruses are independently ...

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