Wu NC, et al. Recurring and Adaptable Binding Motifs in Broadly Neutralizing Antibodies to Influenza Virus Are Encoded on the D3-9 Segment of the Ig Gene. Cell Host Microbe. 2018 Oct 10;24(4):569-578.e4. Abstract
submitted by kickingbird at Oct, 18, 2018 from Cell Host Microbe. 2018 Oct 10;24(4):569-578.e4 (via https://www.ncbi.nlm.nih.gov/pubmed/30308159)
Discovery and characterization of broadly neutralizing antibodies (bnAbs) to the influenza hemagglutinin (HA) stem have provided insights for the development of a universal flu vaccine. Identification ... Vera Ehrenstein, et al. Oseltamivir in pregnancy and birth outcomes. BMC Infectious Diseases201818:519. Abstract
submitted by kickingbird at Oct, 18, 2018 from BMC Infectious Diseases201818:519 (via https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128)
BackgroundPrenatal exposure to influenza or fever is associated with risk of congenital malformations. Oseltamivir is used to treat influenza and to provide post-exposure prophylaxis. We examined the association ... Tomar J, et al. Passive inhalation of dry powder influenza vaccine formulations completely protects chickens against H5N1 lethal viral challenge. Eur J Pharm Biopharm. 2018 Oct 9.. Abstract
submitted by kickingbird at Oct, 17, 2018 from Eur J Pharm Biopharm. 2018 Oct 9. (via https://www.ncbi.nlm.nih.gov/pubmed/30312742)
Bird to human transmission of high pathogenicity avian influenza virus (HPAIV) poses a significant risk of triggering a flu pandemic in the human population. Therefore, vaccination of susceptible poultry ... Zhang J, et al. Role of c-Jun terminal kinase (JNK) activation in influenza A virus-induced autophagy and replication. Virology. 2018 Oct 10;526:1-12.. Abstract
submitted by kickingbird at Oct, 17, 2018 from Virology. 2018 Oct 10;526:1-12. (via https://www.ncbi.nlm.nih.gov/pubmed/30316042)
The non-structural protein 1 (NS1) of different influenza A virus (IAV) strains can differentially regulate the activity of c-Jun terminal kinase (JNK) and PI-3 kinase (PI3K). Whether varying JNK and PI3K ... Ravanetti L, et al. IL-33 drives influenza-induced asthma exacerbations by halting innate and adaptive anti-viral immunity. J Allergy Clin Immunol. 2018 Oct 11. Abstract
submitted by kickingbird at Oct, 17, 2018 from J Allergy Clin Immunol. 2018 Oct 11 (via https://www.ncbi.nlm.nih.gov/pubmed/30316823)
BACKGROUND: Influenza virus triggers severe exacerbations of asthma for which no adequate treatment is available. It is known that IL-33 levels correlate with exacerbation severity, but its role in the ... Noshi T, et al. In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit. Antiviral Res. 2018 Oct 11. Abstract
submitted by kickingbird at Oct, 17, 2018 from Antiviral Res. 2018 Oct 11 (via https://www.ncbi.nlm.nih.gov/pubmed/30316915)
Cap-dependent endonuclease (CEN) resides in the PA subunit of the influenza virus and mediates the critical "cap-snatching" step of viral RNA transcription, which is considered to be a promising anti-influenza ... Zou G, et al. Comprehensive analysis of N-glycans in IgG purified from ferrets with or without influenza A virus infection. J Biol Chem. 2018 Oct 12.. Abstract
submitted by kickingbird at Oct, 17, 2018 from J Biol Chem. 2018 Oct 12. (via https://www.ncbi.nlm.nih.gov/pubmed/30315103)
Influenza viruses cause contagious respiratory infections resulting in significant economic burdens to communities. Production of influenza-specific immunoglobulins, specifically IgGs, is one of the major ... Thompson MG, et al. Influenza Vaccine Effectiveness in Preventing Influenza-associated Hospitalizations During Pregnancy: A Multi-country Retrospective Test Negative Design Study, 2010-2016. Clin Infect Dis. 2018 Oct 11.. Abstract
submitted by kickingbird at Oct, 15, 2018 from Clin Infect Dis. 2018 Oct 11. (via https://www.ncbi.nlm.nih.gov/pubmed/30307490)
Background: To date, no study has examined influenza vaccine effectiveness (IVE) against laboratory-confirmed influenza-associated hospitalizations during pregnancy.Methods: The Pregnancy Influenza Vaccine ... Jegede A, Fu Q, Lin M, Kumar A, Guan J. Aerosol exposure enhanced infection of low pathogenic avian influenza viruses in chickens. Transbound Emerg Dis. 2018 Oct 11.. Abstract
submitted by kickingbird at Oct, 15, 2018 from Transbound Emerg Dis. 2018 Oct 11. (via https://www.ncbi.nlm.nih.gov/pubmed/30307712)
To assess the impact of different routes of inoculation on experimental infection of avian influenza (AI) viruses in chickens, this study compared virus replication and cytokine gene expression in respiratory ... Tome-Amat J, et al. Influenza A virus utilizes low affinity, high avidity interactions with the nuclear import machinery to ensure infection and immune evasion. J Virol. 2018 Oct 10. Abstract
submitted by kickingbird at Oct, 15, 2018 from J Virol. 2018 Oct 10 (via https://www.ncbi.nlm.nih.gov/pubmed/30305352)
The incoming influenza A virus (IAV) genome must pass through two distinct barriers in order to establish infection in the cell- the plasma membrane and the nuclear membrane. A precise understanding of ... Shi B, et al. Identifying key bird species and geographical hotspots of avian influenza A (H7N9) virus in China. Infect Dis Poverty. 2018 Oct 11;7(1):97.. Abstract
submitted by kickingbird at Oct, 15, 2018 from Infect Dis Poverty. 2018 Oct 11;7(1):97. (via https://www.ncbi.nlm.nih.gov/pubmed/30305184)
BACKGROUND: In China since the first human infection of avian influenza A (H7N9) virus was identified in 2013, it has caused serious public health concerns due to its wide spread and high mortality rate. ... Wang L, et al. Inhibition of autophagy and chemokine induction by sphingosine 1-phosphate receptor 1 through NF-κB signaling in human pulmonary endothelial cells infected with influenza A viruses. PLoS One. 2018 Oct 10;13(10):e0205344.. Abstract
submitted by kickingbird at Oct, 15, 2018 from PLoS One. 2018 Oct 10;13(10):e0205344. (via https://www.ncbi.nlm.nih.gov/pubmed/30304001)
Endothelial cells have been considered the central regulators of cytokine storm in the respiratory system during influenza virus infection. Studies have found that elevated autophagy could be an essential ... Nooruzzaman M, Haque ME, Chowdhury EH, Islam MR. Pathology of Clade 2.3.2.1 Avian Influenza Virus (H5N1) Infection in Quails and Ducks in Bangladesh. Avian Pathol. 2018 Oct 10:1-21. Abstract
submitted by kickingbird at Oct, 15, 2018 from Avian Pathol. 2018 Oct 10:1-21 (via https://www.ncbi.nlm.nih.gov/pubmed/30303027)
We performed pathological and molecular virological investigation of three outbreaks of highly pathogenic avian influenza (HPAI) in a quail farm and two duck farms of Mymensingh and Netrokona districts ... Wu H, et al. Molecular characterization of H10 subtype avian influenza viruses isolated from poultry in Eastern China. Arch Virol. 2018 Oct 9. Abstract
submitted by kickingbird at Oct, 15, 2018 from Arch Virol. 2018 Oct 9 (via https://www.ncbi.nlm.nih.gov/pubmed/30302582)
In recent years, avian-origin H10 influenza viruses have proved capable of infecting human beings, and they pose a potential public health threat. Seven H10 avian influenza viruses (AIVs), H10N3 (n?=?2), ... Akand EH, Downard KM. Ancestral and Compensatory Mutations that Promote Antiviral Resistance in Influenza N1 Neuraminidase Revealed by a Phylonumerics Approach. J Mol Evol. 2018 Oct 9.. Abstract
submitted by kickingbird at Oct, 15, 2018 from J Mol Evol. 2018 Oct 9. (via https://www.ncbi.nlm.nih.gov/pubmed/30302501)
Implementation of a new phylonumerics approach to construct a mass tree representing over 6000 H1N1 human influenza strains has enabled ancestral and compensatory descendant mutations to be identified ... Vom Steeg LG, Klein SL. Sex and sex steroids impact influenza pathogenesis across the life course. Semin Immunopathol. 2018 Oct 8. Abstract
submitted by kickingbird at Oct, 15, 2018 from Semin Immunopathol. 2018 Oct 8 (via https://www.ncbi.nlm.nih.gov/pubmed/30298431)
Males and females differ in the outcome of influenza A virus (IAV) infections, which depends significantly on age. During a typical seasonal influenza epidemic, young children ( Beigel JH. Polyclonal and monoclonal antibodies for the treatment of influenza. Curr Opin Infect Dis. 2018 Oct 5.. Abstract
submitted by kickingbird at Oct, 15, 2018 from Curr Opin Infect Dis. 2018 Oct 5. (via https://www.ncbi.nlm.nih.gov/pubmed/30299360)
PURPOSE OF REVIEW: This review summarizes past and ongoing efforts for using polyclonal and monoclonal antibodies for the treatment of influenza, and is focused on products that have entered clinical trials.RECENT ... Vanderbeke L, et al. Invasive pulmonary aspergillosis complicating severe influenza: epidemiology, diagnosis and treatment. Curr Opin Infect Dis. 2018 Oct 5. Abstract
submitted by kickingbird at Oct, 15, 2018 from Curr Opin Infect Dis. 2018 Oct 5 (via https://www.ncbi.nlm.nih.gov/pubmed/30299367)
PURPOSE OF REVIEW: Bacterial superinfection of critically ill influenza patients is well-known, but in recent years, more and more reports describe invasive aspergillosis as a frequent complication as ... Li J, et al.. Continued reassortment of avian H6 influenza viruses from Southern China, 2014~2016. Transbound Emerg Dis. 2018 Oct 9.. Abstract
submitted by kickingbird at Oct, 15, 2018 from Transbound Emerg Dis. 2018 Oct 9. (via https://www.ncbi.nlm.nih.gov/pubmed/30300968)
H6 subtype avian influenza virus (AIV) was prevalent in poultry and could sporadically infect humans. Here, a total of 196 novel H6 AIVs isolated from poultry in eight provinces of China from 2014 to 2016 ... Khurana S, et al. AS03-adjuvanted H5N1 vaccine promotes antibody diversity and affinity maturation, NAI titers, cross-clade H5N1 neutralization, but not H1N1 cross-subtype neutralization. NPJ Vaccines. 2018 Oct 1;3:40.. Abstract
submitted by kickingbird at Oct, 15, 2018 from NPJ Vaccines. 2018 Oct 1;3:40. (via https://www.ncbi.nlm.nih.gov/pubmed/30302282)
Immune responses to inactivated vaccines against avian influenza are poor due in part to lack of immune memory. Adjuvants significantly increased virus neutralizing titers. We performed comprehensive analyses ... 5584 items, 20/Page, Page[145/280][|<<] [|<] [141] [142] [143] [144] [145] [146] [147] [148] [149] [150] [>|] [>>|] |
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