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2024-7-18 5:26:50
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Hemmink JD, Whittaker CJ, Shelton HA. Animal Models in Influenza Research. Methods Mol Biol. 2018;1836:401-430.  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:401-430 (via https://www.ncbi.nlm.nih.gov/pubmed/30151585)
Animal model systems for human and animal influenza virus infection and transmission have been established to address research questions which cannot be addressed using in vitro models. Several animal ...

Karlsson EA, etc.,al. Measuring Influenza Virus Infection Using Bioluminescent Reporter Viruses for In Vivo Imaging and In Vitro Replication Assays. Methods Mol Biol. 2018;1836:431-459.  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:431-459 (via https://www.ncbi.nlm.nih.gov/pubmed/30151586)
To streamline standard virological assays, we developed bioluminescent replication-competent influenza reporter viruses that mimic their parental counterparts. These reporter viruses provide a rapid and ...

Neumann G, Fan S, Kawaoka Y. Selection of Antigenically Advanced Variants of Influenza Viruses. Methods Mol Biol. 2018;1836:461-486.  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:461-486 (via https://www.ncbi.nlm.nih.gov/pubmed/30151587)
Influenza virus epidemics are caused when seasonal influenza viruses (i.e., those circulating in humans) acquire mutations in the antigenic sites of the viral hemagglutinin (HA) protein that prevent the ...

Liu WC, Nachbagauer R, Krammer F, Albrecht RA. Assessment of Influenza Virus Hemagglutinin Stalk-Specific Antibody Responses. Methods Mol Biol. 2018;1836:487-511.  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:487-511 (via https://www.ncbi.nlm.nih.gov/pubmed/30151588)
Animal models are essential to examine the pathogenesis and transmission of influenza viruses and for preclinical evaluation of influenza virus vaccines. Among the animal models used in influenza virus ...

DiPiazza AT, Richards KA, Liu WC, Albrecht RA. Analyses of Cellular Immune Responses in Ferrets Following Influenza Virus Infection. Methods Mol Biol. 2018;1836:513-530.  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:513-530 (via https://www.ncbi.nlm.nih.gov/pubmed/30151589)
Ferrets are an ideal animal model in which to study the transmission of respiratory viruses as well as disease progression and vaccine efficacy because of their close anatomical and physiological resemblances ...

Reimering S, McHardy AC. Software for Characterizing the Antigenic and Genetic Evolution of Human Influenza Viruses. Methods Mol Biol. 2018;1836:551-565.  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Methods Mol Biol. 2018;1836:551-565 (via https://www.ncbi.nlm.nih.gov/pubmed/30151591)
Influenza viruses are rapidly evolving pathogens causing annual epidemics and occasional pandemics. The accumulation of amino acid substitutions allows the virus to adapt to changing environments like ...

Tian T, etc.,al. H3N2 influenza virus infection enhances Oncostatin M expression in human nasal epithelium. Exp Cell Res. 2018 Aug 21.  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Exp Cell Res. 2018 Aug 21 (via https://www.ncbi.nlm.nih.gov/pubmed/30142324)
Tight junctions (TJs) alteration is commonly seen in airway inflammatory diseases. Oncostatin M (OSM) is an inflammatory mediator associated with chronic rhinosinusitis with nasal polyps (CRSwNP). We have ...

D´Agostino I, etc.,al. Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction. Eur J Med Chem. 2018 Aug 13;157:743-758.  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Eur J Med Chem. 2018 Aug 13;157:743-758 (via https://www.ncbi.nlm.nih.gov/pubmed/30142611)
The limited treatment options against influenza virus along with the growing public health concerns regarding the continuous emergence of drug-resistant viruses make essential the development of new anti-flu ...

Kronstad LM, Seiler C, Vergara R, Holmes SP. Differential Induction of IFN-α and Modulation of CD112 and CD54 Expression Govern the Magnitude of NK Cell IFN-γ Response to Influenza A Viruses. J Immunol. 2018 Aug 24. pii: ji1800161..  Abstract  
submitted by kickingbird at Aug, 31, 2018 from J Immunol. 2018 Aug 24. pii: ji1800161. (via https://www.ncbi.nlm.nih.gov/pubmed/30143589)
In human and murine studies, IFN-γ is a critical mediator immunity to influenza. IFN-γ production is critical for viral clearance and the development of adaptive immune responses, yet excessive production ...

Ermolenko EI, etc.,al. Anti-Influenza Activity of Enterocin B In vitro and Protective Effect of Bacteriocinogenic Enterococcal Probiotic Strain on Influenza Infection in Mouse Model. Probiotics Antimicrob Proteins. 2018 Aug 24..  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Probiotics Antimicrob Proteins. 2018 Aug 24. (via https://www.ncbi.nlm.nih.gov/pubmed/30143997)
In spite of scientific evidence demonstrating the antiviral activity of lactic-acids bacteria, little is known about the mechanism of their action. Previously, several bacteriocins isolated from lactic ...

Ismail ZM, El-Deeb AH, El-Safty MM, Hussein HA. Enhanced pathogenicity of low-pathogenic H9N2 avian influenza virus after vaccination with infectious bronchitis live attenuated vaccine. Vet World. 2018 Jul;11(7):977-985.  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Vet World. 2018 Jul;11(7):977-985 (via https://www.ncbi.nlm.nih.gov/pubmed/30147269)
Aim: In the present study, two experiments were carried out for studying the pathogenicity of H9N2 avian influenza virus (AIV) in broiler chickens after vaccination with different live respiratory viral ...

Veerapandian R, Snyder JD, Samarasinghe AE. Influenza in Asthmatics: For Better or for Worse?. Front Immunol. 2018 Aug 10;9:1843.  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Front Immunol. 2018 Aug 10;9:1843 (via https://www.ncbi.nlm.nih.gov/pubmed/30147697)
Asthma and influenza are two pathologic conditions of the respiratory tract that affect millions worldwide. Influenza virus of the 2009 pandemic was highly transmissible and caused severe respiratory disease ...

Zheng D, Gao F, Zhao C, Ding Y, Cao Y. Comparative effectiveness of H7N9 vaccines in healthy individuals. Hum Vaccin Immunother. 2018 Aug 27..  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Hum Vaccin Immunother. 2018 Aug 27. (via https://www.ncbi.nlm.nih.gov/pubmed/30148691)
BACKGROUND: Avian H7N9 influenza viruses possess a potential pandemic threat to public health worldwide, and have caused severe infection and high mortality in humans. A series of clinical trials of H7N9 ...

Benkaroun J, Robertson GJ, Whitney H, Lang AS. Analysis of the Variability in the Non-Coding Regions of Influenza A Viruses. Vet Sci. 2018 Aug 25;5(3)..  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Vet Sci. 2018 Aug 25;5(3). (via https://www.ncbi.nlm.nih.gov/pubmed/30149635)
The genomes of influenza A viruses (IAVs) comprise eight negative-sense single-stranded RNA segments. In addition to the protein-coding region, each segment possesses 5' and 3' non-coding regions (NCR) ...

Ni Y, Guo J, Turner D, Tizard I. An Improved Inactivated Influenza Vaccine with Enhanced Cross Protection. Front Immunol. 2018 Aug 9;9:1815..  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Front Immunol. 2018 Aug 9;9:1815. (via https://www.ncbi.nlm.nih.gov/pubmed/30140267)
Current inactivated influenza vaccines are strain-specific and poorly effective against variant or mismatched viruses. They are standardized based on their hemagglutinin (HA) or ability to induce strain-specific ...

Li R, Zhang T, Bai Y, Li H, Wang Y, Bi Y, Chang J. Live Poultry Trading Drives China´s H7N9 Viral Evolution and Geographical Network Propagation. Front Public Health. 2018 Jul 27;6:210.  Abstract  
submitted by kickingbird at Aug, 31, 2018 from Front Public Health. 2018 Jul 27;6:210 (via https://www.ncbi.nlm.nih.gov/pubmed/30140667)
The on-going reassortment, human-adapted mutations, and spillover events of novel A(H7N9) avian influenza viruses pose a significant challenge to public health in China and globally. However, our understanding ...

Saavedra-Monta?ez M, etc.,al. Identification and genomic characterization of influenza viruses with different origin in Mexican pigs. Transbound Emerg Dis. 2018 Aug 20.  Abstract  
submitted by kickingbird at Aug, 24, 2018 from Transbound Emerg Dis. 2018 Aug 20 (via https://www.ncbi.nlm.nih.gov/pubmed/30126057)
Swine influenza is a worldwide disease, which causes damage to the respiratory system of pigs. The H1N1 and H3N2 subtypes circulate mainly in the swine population of Mexico. There is evidence that new ...

Wang J, etc.,al. A study on mother-to-fetus/infant transmission of influenza A(H7N9) virus: two case reports and a review of literature. Clin Respir J. 2018 Aug 20.  Abstract  
submitted by kickingbird at Aug, 24, 2018 from Clin Respir J. 2018 Aug 20 (via https://www.ncbi.nlm.nih.gov/pubmed/30126042)
OBJECTIVES: The prevention strategies for mother-to-fetus/infant transmission of H7N9 virus have not been well understood, and the study on this subject will provide further insights.METHODS: Reverse transcriptase ...

Xia C, Seo YJ, Studstill CJ, Vijayan M, Wolf J. Transient inhibition of sphingosine kinases confers protection to influenza A virus infected mice. Antiviral Res. 2018 Aug 17. pii: S0166-3542(18)302.  Abstract  
submitted by kickingbird at Aug, 24, 2018 from Antiviral Res. 2018 Aug 17. pii: S0166-3542(18)302 (via https://www.ncbi.nlm.nih.gov/pubmed/30125617)
Influenza continues to pose a threat to public health by causing illness and mortality in humans. Discovering host factors that regulate influenza virus propagation is vital for the development of novel ...

Sood R, etc.,al. Neuraminidase inhibitors susceptibility profiles of highly pathogenic influenza A (H5N1) viruses isolated from avian species in India (2006-2015).. Antiviral Res. 2018 Aug 17..  Abstract  
submitted by kickingbird at Aug, 24, 2018 from Antiviral Res. 2018 Aug 17. (via https://www.ncbi.nlm.nih.gov/pubmed/30125616)
We tested 65 highly pathogenic avian influenza (HPAI) A(H5N1) viruses, isolated from avian species in India between 2006 and 2015, for susceptibility to the FDA approved neuraminidase (NA) inhibitors (NAIs), ...

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