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2024-5-3 16:12:26
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Jacqueline M. Nolting Scott D. Scheer Andrew S.. Perceptions and attitudes of swine exhibitors towards recommendations for reducing zoonotic transmission of influenza A viruses. Zoonoses and Public Health 06 Mar 2019.  Abstract  
submitted by kickingbird at Mar, 10, 2019 from Zoonoses and Public Health 06 Mar 2019 (via https://onlinelibrary.wiley.com/doi/abs/10.1111/zph.12574)
Since 2011, there have been 468 cases of variant influenza A virus (IAV) reported in the United States, many of which were associated with youth swine exhibition. In an effort to mitigate risk associated ...

Mandala VS, Liao SY, Gelenter MD, Hong M. The Transmembrane Conformation of the Influenza B Virus M2 Protein in Lipid Bilayers. Sci Rep. 2019 Mar 6;9(1):3725..  Abstract  
submitted by kickingbird at Mar, 10, 2019 from Sci Rep. 2019 Mar 6;9(1):3725. (via https://www.nature.com/articles/s41598-019-40217-1)
Influenza A and B viruses cause seasonal flu epidemics. The M2 protein of influenza B (BM2) is a membrane-embedded tetrameric proton channel that is essential for the viral lifecycle. BM2 is a functional ...

Liu Y, et al. CRISPR-Cas13a Nanomachine Based Simple Technology for Avian Influenza A (H7N9) Virus On-Site Detection. J Biomed Nanotechnol. 2019 Apr 1;15(4):790-798.  Abstract  
submitted by kickingbird at Mar, 10, 2019 from J Biomed Nanotechnol. 2019 Apr 1;15(4):790-798 (via https://www.ingentaconnect.com/content/asp/jbn/2019/00000015)
It is urgent to find an avian influenza A H7N9 detection simple method which is suitable for on-site detection. The Cas13a protein just likes a nanomachine, when specifically bound to target RNA by single-stranded ...

Yamaya M, et al. Effects of high temperature on pandemic and seasonal human influenza viral replication and infection-induced damage in primary human tracheal epithelial cell cultures. Heliyon. 2019 Feb 5;5(2):e01149.  Abstract  
submitted by kickingbird at Mar, 8, 2019 from Heliyon. 2019 Feb 5;5(2):e01149 (via https://www.heliyon.com/article/e01149)
High temperature reduces influenza viral replication; however, the treatment of fevers is thought to be necessary to improve patients' conditions. We examined the effects of high temperature on viral replication ...

Teo SHC, Wu JP, Mok CK, Tan YJ. A NS1-Binding Monoclonal Antibody Interacts with Two Residues that are Highly Conserved in Seasonal as well as Newly-Emerged Influenza A Virus. Pathog Dis. 2019 Mar 6.  Abstract  
submitted by kickingbird at Mar, 8, 2019 from Pathog Dis. 2019 Mar 6 (via https://academic.oup.com/femspd/advance-article-abstract/doi)
The non-structural protein 1 (NS1) of influenza A virus (IAV) is a multifunctional protein that antagonizes host antiviral responses, modulating virus pathogenesis. As such, it serves as a good target ...

Krammer F. The human antibody response to influenza A virus infection and vaccination. Nat Rev Immunol. 2019 Mar 5..  Abstract  
submitted by kickingbird at Mar, 8, 2019 from Nat Rev Immunol. 2019 Mar 5. (via https://www.nature.com/articles/s41577-019-0143-6)
The adaptive immune response to influenza virus infection is multifaceted and complex, involving antibody and cellular responses at both systemic and mucosal levels. Immune responses to natural infection ...

Bajic G, et al. Autoreactivity profiles of influenza hemagglutinin broadly neutralizing antibodies. Sci Rep. 2019 Mar 5;9(1):3492..  Abstract  
submitted by kickingbird at Mar, 8, 2019 from Sci Rep. 2019 Mar 5;9(1):3492. (via https://www.nature.com/articles/s41598-019-40175-8)
Epitope-focused approaches for selective clonal induction of broadly neutralizing antibodies (bnAbs) inform most current vaccine strategies for influenza virus and other rapidly evolving pathogens. The ...

Taniguchi K, et al. Inhibition of avian-origin influenza A(H7N9) virus by the novel cap-dependent endonuclease inhibitor baloxavir marboxil. Sci Rep. 2019 Mar 5;9(1):3466..  Abstract  
submitted by kickingbird at Mar, 8, 2019 from Sci Rep. 2019 Mar 5;9(1):3466. (via https://www.nature.com/articles/s41598-019-39683-4)
Human infections with avian-origin influenza A(H7N9) virus represent a serious threat to global health; however, treatment options are limited. Here, we show the inhibitory effects of baloxavir acid (BXA) ...

Nu?ez IA, Ross TM. A review of H5Nx avian influenza viruses. Ther Adv Vaccines Immunother. 2019 Feb 22;7:251513.  Abstract  
submitted by kickingbird at Mar, 7, 2019 from Ther Adv Vaccines Immunother. 2019 Feb 22;7:251513 (via https://journals.sagepub.com/doi/10.1177/2515135518821625)
Highly pathogenic avian influenza viruses (HPAIVs), originating from the A/goose/Guangdong/1/1996 H5 subtype, naturally circulate in wild-bird populations, particularly waterfowl, and often spill over ...

Beale DJ, et al. Untargeted metabolomics analysis of the upper respiratory tract of ferrets following influenza A virus infection and oseltamivir treatment. Metabolomics. 2019 Mar 1;15(3):33.  Abstract  
submitted by kickingbird at Mar, 5, 2019 from Metabolomics. 2019 Mar 1;15(3):33 (via https://link.springer.com/article/10.1007%2Fs11306-019-1499-)
INTRODUCTION: Influenza is a highly contagious respiratory disease that causes high global morbidity and mortality each year. The dynamics of an influenza infection on the host metabolism, and how metabolism ...

Sisteré-Oró M, et al. Conserved HA-peptide NG34 formulated in pCMV-CTLA4-Ig reduces viral shedding in pigs after a heterosubtypic influenza virus SwH3N2 challenge. PLoS One. 2019 Mar 1;14(3):e0212431.  Abstract  
submitted by kickingbird at Mar, 4, 2019 from PLoS One. 2019 Mar 1;14(3):e0212431 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Swine influenza viruses (SIVs), the causal agents of swine influenza, are not only important to control due to the economic losses in the swine industry, but also can be pandemic pathogens. Vaccination ...

Umut Karakus, et al. MHC class II proteins mediate cross-species entry of bat influenza viruses. Nature 20 Feb, 2019.  Abstract  
submitted by kickingbird at Mar, 3, 2019 from Nature 20 Feb, 2019 (via https://www.nature.com/articles/s41586-019-0955-3)
Zoonotic influenza A viruses of avian origin can cause severe disease in individuals, or even global pandemics, and thus pose a threat to human populations. Waterfowl and shorebirds are believed to be ...

Lim KS, et al. Direct visualization of avian influenza H5N1 Hemagglutinin precursor and its conformational change by high-speed atomic force microscopy. Biochim Biophys Acta Gen Subj. 2019 Feb 27..  Abstract  
submitted by kickingbird at Mar, 3, 2019 from Biochim Biophys Acta Gen Subj. 2019 Feb 27. (via https://www.sciencedirect.com/science/article/pii/S030441651)
BACKGROUND: Hemagglutinin (HA) of influenza A is one of the key virulence factors that mediates the release of viral components in host cells. HA is initially synthesized as a trimeric precursor (HA0) ...

Paulino J, Pang X, Hung I, Zhou HX, Cross TA. Influenza A M2 Channel Clustering at High Protein/Lipid Ratios: Viral Budding Implications. Biophys J. 2019 Feb 10.  Abstract  
submitted by kickingbird at Mar, 3, 2019 from Biophys J. 2019 Feb 10 (via https://www.cell.com/biophysj/fulltext/S0006-3495(19)30114-6)
Protein dynamics in crowded environments is important for understanding protein functions in vivo and is especially relevant for membrane proteins because of the roles of protein-protein interactions in ...

Lalueza A, et al. Influence of viral load in the outcome of hospitalized patients with influenza virus infection. Eur J Clin Microbiol Infect Dis. 2019 Feb 28..  Abstract  
submitted by kickingbird at Mar, 3, 2019 from Eur J Clin Microbiol Infect Dis. 2019 Feb 28. (via https://link.springer.com/article/10.1007%2Fs10096-019-03514)
The role of viral load in the outcome of patients requiring hospital admission due to influenza is not well established. We aim to assess if there is an association between the viral load and the outcome ...

Shepardson K, et al. A Novel Role for PDZ-Binding Motif of Influenza A Virus Nonstructural Protein 1 in Regulation of Host Susceptibility to Postinfluenza Bacterial Superinfections. Viral Immunol. 2019 Mar 1..  Abstract  
submitted by kickingbird at Mar, 3, 2019 from Viral Immunol. 2019 Mar 1. (via https://www.liebertpub.com/doi/10.1089/vim.2018.0118)
Influenza A viruses (IAVs) have multiple mechanisms for altering the host immune response to aid in virus survival and propagation. While both type I and II interferons (IFNs) have been associated with ...

Zeng H, et al. Tropism and Infectivity of a Seasonal A(H1N1) and a Highly Pathogenic Avian A(H5N1) Influenza Virus in Primary Differentiated Ferret Nasal Epithelial Cell Cultures. J Virol. 2019 Feb 27..  Abstract  
submitted by kickingbird at Mar, 1, 2019 from J Virol. 2019 Feb 27. (via https://jvi.asm.org/content/early/2019/02/22/JVI.00080-19)
Ferrets represent an invaluable animal model to study influenza virus pathogenesis and transmission. To further characterize this model, we developed a differentiated primary ferret nasal epithelial cell ...

Tang YS, Lo CY, Mok CK, Chan PK, Shaw PC. The extended C-terminal region of influenza C nucleoprotein is important for nuclear import and RNP activity. J Virol. 2019 Feb 27.  Abstract  
submitted by kickingbird at Mar, 1, 2019 from J Virol. 2019 Feb 27 (via https://jvi.asm.org/content/early/2019/02/22/JVI.02048-18)
The influenza C virus (ICV) is a human pathogenic agent and the infections are frequently identified in children. Compared to influenza A and B viruses, the nucleoprotein of ICV (NPC) has an extended C-terminal ...

Lu Y, et al. In Vivo Characterization of Avian Influenza A (H5N1) and (H7N9) Viruses Isolated from Canadian Travelers. Viruses. 2019 Feb 23;11(2)..  Abstract  
submitted by kickingbird at Mar, 1, 2019 from Viruses. 2019 Feb 23;11(2). (via https://www.mdpi.com/1999-4915/11/2/193)
Highly pathogenic avian influenza (HPAI) H5N1 and low pathogenic avian influenza (LPAI) H7N9 viruses pose a severe threat to public health through zoonotic infection, causing severe respiratory disease ...

Blanco-Lobo P, Nogales A, Rodríguez L, etc al. Novel Approaches for The Development of Live Attenuated Influenza Vaccines. Viruses. 2019 Feb 22;11(2)..  Abstract  
submitted by kickingbird at Mar, 1, 2019 from Viruses. 2019 Feb 22;11(2). (via https://www.mdpi.com/1999-4915/11/2/190)
Influenza virus still represents a considerable threat to global public health, despite the advances in the development and wide use of influenza vaccines. Vaccination with traditional inactivate influenza ...

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