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2024-11-26 6:00:33
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Makarkov AI, Chierzi S, Pillet S, Murai KK, et al. Plant-made virus-like particles bearing influenza hemagglutinin (HA) recapitulate early interactions of native influenza virions with human monocytes/macrophages. Vaccine 2017 Jul 13. pii: S0264-410X(17)30908.  Abstract  
submitted by kickingbird at Jul, 23, 2017 from Vaccine 2017 Jul 13. pii: S0264-410X(17)30908 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28712489/)
INTRODUCTION: Plant-made virus-like particles (VLP) bearing influenza virus hemagglutinins (HA) are novel vaccine candidates that induce cross-reactive humoral and poly-functional T cell responses. To ...

Nturibi E, Bhagwat AR, Coburn S, Myerburg MM, et a. Intracellular Colocalization of Influenza Viral RNA and Rab11A is Dependent upon Microtubule Filaments. J Virol 2017 Jul 19.  Abstract  
submitted by kickingbird at Jul, 23, 2017 from J Virol 2017 Jul 19 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28724771/)
Influenza A virus (IAV) consists of eight viral RNA (vRNA) segments that are replicated in the host cell nucleus and transported to the plasma membrane for packaging into progeny virions. We have previously ...

Tully CM, Chinnakannan S, Mullarkey CE, Ulaszewska. Novel Bivalent Viral-Vectored Vaccines Induce Potent Humoral and Cellular Immune Responses Conferring Protection against Stringent Influenza A Virus Challenge. J Immunol 2017 Jul 19.  Abstract  
submitted by kickingbird at Jul, 23, 2017 from J Immunol 2017 Jul 19 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28724579/)
Seasonal influenza viruses are a common cause of acute respiratory illness worldwide and generate a significant socioeconomic burden. Influenza viruses mutate rapidly, necessitating annual vaccine reformulation ...

Kandeil A, Kayed A, Moatasim Y, Webby RJ, et al. Genetic characterization of highly pathogenic avian influenza A H5N8 viruses isolated from wild birds in Egypt. J Gen Virol 2017 Jul 18..  Abstract  
submitted by kickingbird at Jul, 23, 2017 from J Gen Virol 2017 Jul 18. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28721841/)
A newly emerged H5N8 influenza virus was isolated from green-winged teal in Egypt during December 2016. In this study, we provide a detailed characterization of full genomes of Egyptian H5N8 viruses and ...

Zhai S, Zhang H, Chen S, Zhou X, Lin T, Liu R, et. Influenza D Virus in Animal Species in Guangdong Province, Southern China. Emerg Infect Dis. 2017;23(8):1392-1396.  Abstract  
submitted by kickingbird at Jul, 18, 2017 from Emerg Infect Dis. 2017;23(8):1392-1396 (via https://wwwnc.cdc.gov/eid/article/23/8/17-0059_article)
Molecular tests revealed influenza D viruses of D/OK lineage widely circulating in farmed animal species in Guangdong Province, southern China. In particular, we found high levels of influenza D virus ...

El-Shesheny R, Barman S, Feeroz MM, Hasan M, Jones. Genesis of Influenza A(H5N8) Viruses. Emerg Infect Dis. 2017;23(8):1368-1371.  Abstract  
submitted by kickingbird at Jul, 18, 2017 from Emerg Infect Dis. 2017;23(8):1368-1371 (via https://wwwnc.cdc.gov/eid/article/23/8/17-0143_article)
Highly pathogenic avian influenza A(H5N8) clade 2.3.4.4 virus emerged in 2016 and spread to Russia, Europe, and Africa. Our analysis of viruses from domestic ducks at Tanguar haor, Bangladesh, showed genetic ...

Goldeck D, Theeten H, Hassouneh F, Oettinger L, et. Frequencies of peripheral immune cells in older adults following seasonal influenza vaccination with an adjuvanted vaccine. Vaccine 2017 Jul 6..  Abstract  
submitted by kickingbird at Jul, 18, 2017 from Vaccine 2017 Jul 6. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28689651/)
As age increases, immune responses and consequently protection following vaccination to seasonal influenza is commonly believed to decrease. Possible drivers of this immune dysfunction include immunosenescence, ...

Blackmore S, Hernandez J, Juda M, Ryder E, et al. Influenza infection triggers disease in a genetic model of experimental autoimmune encephalomyelitis. Proc Natl Acad Sci U S A 2017 Jul 10.  Abstract  
submitted by kickingbird at Jul, 18, 2017 from Proc Natl Acad Sci U S A 2017 Jul 10 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28696309/)
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system. Most MS patients experience periods of symptom exacerbation (relapses) followed by periods of partial recovery (remission). ...

Sutton TC, Lamirande EW, Czako R, Subbarao K, et a. Evaluation of the biological properties and cross-reactive antibody response to H10 influenza viruses in ferrets. J Virol 2017 Jul 12.  Abstract  
submitted by kickingbird at Jul, 18, 2017 from J Virol 2017 Jul 12 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28701401/)
The recent outbreak of avian origin H10N7 influenza among seals in Northern Europe, and two fatal human infections with an avian H10N8 virus in China, have demonstrated that H10 viruses can spread between ...

Morse K, Kimizuka Y, Chan MPK, Shibata M, et al. Near-Infrared 1064 nm Laser Modulates Migratory Dendritic Cells To Augment the Immune Response to Intradermal Influenza Vaccine. J Immunol 2017 Jul 14.  Abstract  
submitted by kickingbird at Jul, 18, 2017 from J Immunol 2017 Jul 14 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28710250/)
Brief exposure of skin to near-infrared (NIR) laser light has been shown to augment the immune response to intradermal vaccination and thus act as an immunologic adjuvant. Although evidence indicates that ...

Xin Li, Bai Tian, etc.,al. A comprehensive retrospective study of the seroprevalence of H9N2 avian influenza viruses in occupationally exposed populations in China. PLoS One. 2017 Jun 2;12(6):e0178328.  Abstract  
submitted by kickingbird at Jul, 12, 2017 from PLoS One. 2017 Jun 2;12(6):e0178328 (via http://journals.plos.org/plosone/article?id=10.1371/journal.)
The H9N2 avian influenza virus circulates worldwide, predominantly in poultry. Its increasing infectivity and adaptation in poultry and mammals have enhanced the possibility of human infection. However, ...

Hatta Y, Boltz D, Sarawar S, Kawaoka Y, et al. M2SR, a novel live influenza vaccine, protects mice and ferrets against highly pathogenic avian influenza. Vaccine 2017 Jun 28.  Abstract  
submitted by kickingbird at Jul, 10, 2017 from Vaccine 2017 Jun 28 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28668565/)
The emergence of highly pathogenic avian influenza H5N1 viruses has heightened global concern about the threat posed by pandemic influenza. To address the need for a highly effective universal influenza ...

Wu UI, Hsieh SM, Lee WS, Wang NC, et al. Safety and immunogenicity of an inactivated cell culture-derived H7N9 influenza vaccine in healthy adults: A phase I/II, prospective, randomized, open-label trial. Vaccine 2017 Jun 28.  Abstract  
submitted by kickingbird at Jul, 10, 2017 from Vaccine 2017 Jun 28 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28668573/)
BACKGROUND: We conducted a phase I/II clinical trial to evaluate the safety and immunogenicity of a Madin-Darby canine kidney (MDCK) cell-grown inactivated H7N9 influenza vaccine for pandemic preparedness ...

ini H, Ghalyanchilangeroudi A, Fallah Mehrabadi MH. Phylogenetic analysis of H9N2 avian influenza viruses in Afghanistan (2016-2017). Arch Virol. 2017..  Abstract  
submitted by kickingbird at Jul, 10, 2017 from Arch Virol. 2017. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28674864/)
Avian influenza A virus (AIV) subtype H9N2 is the most prevalent subtype found in terrestrial poultry throughout Eurasia and has been isolated from poultry outbreaks worldwide. Tracheal tissue specimens ...

Kang M, Lau EHY, Guan W, Yang Y, Song T, Cowling B. Epidemiology of human infections with highly pathogenic avian influenza A(H7N9) virus in Guangdong, 2016 to 2017. Euro Surveill. 2017;22(27):pii=30568.  Abstract  
submitted by kickingbird at Jul, 7, 2017 from Euro Surveill. 2017;22(27):pii=30568 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
We describe the epidemiology of highly pathogenic avian influenza (HPAI) A(H7N9) based on poultry market environmental surveillance and laboratory-confirmed human cases (n?=?9) in Guangdong, ...

Shubhada K. Chothe, Gitanjali Bhushan, etc.,al. Avian and human influenza virus compatible sialic acid receptors in little brown bats. Scientific Reports 7, Article number: 660 (2017).  Abstract  
submitted by kickingbird at Jul, 7, 2017 from Scientific Reports 7, Article number: 660 (2017) (via http://www.nature.com/articles/s41598-017-00793-6)
Influenza A viruses (IAVs) continue to threaten animal and human health globally. Bats are asymptomatic reservoirs for many zoonotic viruses. Recent reports of two novel IAVs in fruit bats and serological ...

Rouphael NG, Paine M, Mosley R, Henry S, et al. The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial. Lancet 2017 Jun 27..  Abstract  
submitted by kickingbird at Jul, 3, 2017 from Lancet 2017 Jun 27. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28666680/)
BACKGROUND: Microneedle patches provide an alternative to conventional needle-and-syringe immunisation, and potentially offer improved immunogenicity, simplicity, cost-effectiveness, acceptability, and ...

Venereo-Sanchez A, Simoneau M, Lanthier S, Chahal. Process intensification for high yield production of influenza H1N1 Gag virus-like particles using an inducible HEK-293 stable cell line. Vaccine 2017 Jun 22.  Abstract  
submitted by kickingbird at Jul, 3, 2017 from Vaccine 2017 Jun 22 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28648546/)
Influenza virus dominant antigens presentation using virus like particle (VLP) approach is attractive for the development of new generation of influenza vaccines. Mammalian cell platform offers many advantages ...

Diaz A, Marthaler D, Culhane M, Sreevatsan S, et a. Complete Genome Sequencing of Influenza A Viruses within Swine Farrow-to-Wean Farms Reveals the Emergence, Persistence, and Subsidence of Diverse Viral Genotypes. J Virol 2017 Jun 28.  Abstract  
submitted by kickingbird at Jul, 3, 2017 from J Virol 2017 Jun 28 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28659482/)
Influenza A viruses (IAVs) are endemic in swine and represent a public health risk. However, there is limited information on the genetic diversity of swine IAVs within farrow-to-wean farms, which is where ...

Nam JH, Shim SM, Song EJ, Espano E, et al. Rapid virulence shift of an H5N2 avian influenza virus during a single passage in mice. Arch Virol 2017 Jun 29.  Abstract  
submitted by kickingbird at Jul, 3, 2017 from Arch Virol 2017 Jun 29 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28664296/)
Influenza A viruses must undergo adaptation to acquire virulence in new host species. In mouse models, host adaptation for virulence is generally performed through 5 to 20 lung-to-lung passages. However, ...

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