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2024-4-27 12:05:17
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KALTHOFF D, Rohrs S, Hoper D, Hoffmann B, et al. Truncation and sequence shuffling of segment 6 generate replication-competent neuraminidase-negative influenza H5N1 viruses. J Virol. 2013 Oct 9..  Abstract  
submitted by kickingbird at Oct, 13, 2013 from J Virol. 2013 Oct 9. (via http://www.ncbi.nlm.nih.gov/pubmed/24109212)
Influenza viruses are highly genetically variable and escape from immunogenic pressure by antigenic changes in their surface proteins referred to as antigenic drift and antigenic shift. To assess the potential ...

JEGASKANDA S, Amarasena TH, Laurie KL, Tan HX, et. Standard trivalent influenza protein vaccination does not prime antibody-dependent cellular cytotoxicity (ADCC) in macaques. J Virol. 2013 Oct 9..  Abstract  
submitted by kickingbird at Oct, 13, 2013 from J Virol. 2013 Oct 9. (via http://www.ncbi.nlm.nih.gov/pubmed/24109221)
Yearly vaccination with the trivalent inactivated influenza vaccine (TIV) is recommended since current vaccines induce little cross neutralization to divergent influenza strains. Whether the TIV can induce ...

PERWITASARI O, Torrecilhas AC, Yan X, Johnson S, e. Targeting Cell Division Cycle 25 Homolog B (CDC25B) to Regulate Influenza Virus Replication. J Virol. 2013 Oct 9.  Abstract  
submitted by kickingbird at Oct, 13, 2013 from J Virol. 2013 Oct 9 (via http://www.ncbi.nlm.nih.gov/pubmed/24109234)
Influenza virus is a worldwide global health concern causing seasonal morbidity, mortality, and economic burden. Chemotherapeutics is available however rapid emergence of drug resistant influenza strains ...

SPENCER S, Gaglani M, Naleway A, Reynolds S, et al. Consistency of influenza A test results across respiratory specimen collection methods using real time reverse transcription polymerase chain reaction. J Clin Microbiol. 2013 Oct 9..  Abstract  
submitted by kickingbird at Oct, 13, 2013 from J Clin Microbiol. 2013 Oct 9. (via http://www.ncbi.nlm.nih.gov/pubmed/24108606)
In our prospective cohort study, we compared the performance of nasopharyngeal, oropharyngeal, and nasal swabs for the detection of influenza using real-time reverse transcription polymerase chain reaction ...

Chong KC, Fong HF, Zee CY.. Estimating the incidence reporting rates of new influenza pandemics at an early stage using travel data from the source country. Epidemiol Infect. 2013 Oct 10:1-9..  Abstract  
submitted by kickingbird at Oct, 13, 2013 from Epidemiol Infect. 2013 Oct 10:1-9. (via http://www.ncbi.nlm.nih.gov/pubmed/24107289)
SUMMARY During the surveillance of influenza pandemics, underreported data are a public health challenge that complicates the understanding of pandemic threats and can undermine mitigation efforts. We ...

Liao Q, Qian Z, Liu R, An L, Chen X.. Germacrone inhibits early stages of influenza virus infection. Antiviral Res. 2013 Oct 3. pii: S0166-3542.  Abstract  
submitted by kickingbird at Oct, 13, 2013 from Antiviral Res. 2013 Oct 3. pii: S0166-3542 (via http://www.ncbi.nlm.nih.gov/pubmed/24095670)
Highly pathogenic influenza viruses pose a serious public health threat to humans. Although vaccines are available, antivirals are needed to efficiently control disease progression and virus transmission ...

Tong S, Zhu X, Li Y, Shi M, Zhang J, et al. New World Bats Harbor Diverse Influenza A Viruses. PLoS Pathog 9(10): e1003657. doi:10.1371/journal..  Abstract  
submitted by kickingbird at Oct, 12, 2013 from PLoS Pathog 9(10): e1003657. doi:10.1371/journal. (via http://www.plospathogens.org/article/info%3Adoi%2F10.1371%2F)
Aquatic birds harbor diverse influenza A viruses and are a major viral reservoir in nature. The recent discovery of influenza viruses of a new H17N10 subtype in Central American fruit bats suggests that ...

YAMAMOTO N, Sakoda Y, Okamatsu M, Kida H, et al. Polymerase complex with lysine at position 627 of the PB2 of influenza virus A/Hong Kong/483/97 (H5N1) efficiently transcribes and replicates virus genes in mouse cells. Virus Res. 2013 Sep 23..  Abstract  
submitted by kickingbird at Oct, 6, 2013 from Virus Res. 2013 Sep 23. (via http://www.ncbi.nlm.nih.gov/pubmed/24070983)
Influenza virus A/Hong Kong/483/97 (H5N1) (HK483-K) has the PB2 with lysine at position 627 (PB2-627K) and is highly pathogenic in chickens and mice. On the other hand, the pathogenicity of mutant virus ...

NI F, Kondrashkina E, Wang Q. Structural basis for the divergent evolution of influenza B virus hemagglutinin. Virology. 2013 Nov.  Abstract  
submitted by kickingbird at Oct, 6, 2013 from Virology. 2013 Nov (via http://www.ncbi.nlm.nih.gov/pubmed/24074573)
Influenza A and B viruses are responsible for the severe morbidity and mortality worldwide in annual influenza epidemics. Currently circulating influenza B virus belongs to the B/Victoria or B/Yamagata ...

YE J, Xu Y, Harris J, Sun H, et al. Mutation from arginine to lysine at the position 189 of hemagglutinin contributes to the antigenic drift in H3N2 swine influenza viruses. Virology. 2013 Nov;.  Abstract  
submitted by kickingbird at Oct, 6, 2013 from Virology. 2013 Nov; (via http://www.ncbi.nlm.nih.gov/pubmed/24074585)
Two distinct antigenic clusters were previously identified among the H3N2 swine influenza A viruses (IAVs) and were designated H3N2SIV-alpha and H3N2SIV-beta (Feng et al., 2013. Journal of Virology 87 ...

LAKDAWALA SS, Shih AR, Jayaraman A, Lamirande EW,. Receptor specificity does not affect replication or virulence of the 2009 pandemic H1N1 influenza virus in mice and ferrets. Virology. 2013 Nov.  Abstract  
submitted by kickingbird at Oct, 6, 2013 from Virology. 2013 Nov (via http://www.ncbi.nlm.nih.gov/pubmed/24074599)
Human influenza viruses predominantly bind α2,6 linked sialic acid (SA) while avian viruses bind α2,3 SA-containing complex glycans. Virulence and tissue tropism of influenza viruses have been ascribed ...

SELADI-SCHULMAN J, Steel J, Lowen AC. Spherical influenza viruses have a fitness advantage in embryonated eggs, while filament-producing strains are selected in vivo. J Virol. 2013 Oct 2.  Abstract  
submitted by kickingbird at Oct, 6, 2013 from J Virol. 2013 Oct 2 (via http://www.ncbi.nlm.nih.gov/pubmed/24089563)
Influenza viruses can take on two distinct morphologies: filamentous or spherical. While the functional significance of each virion type is unclear, filaments are generally observed in low-passage isolates ...

Tran V, Moser LA, Poole DS, Mehle A.. Highly sensitive real-time in vivo imaging of an influenza reporter virus reveals dynamics of replication and spread.. J Virol. 2013 Oct 2..  Abstract  
submitted by kickingbird at Oct, 6, 2013 from J Virol. 2013 Oct 2. (via http://www.ncbi.nlm.nih.gov/pubmed/24089552)
The continual public health threat posed by the emergence of novel influenza viruses necessitates the ability to rapidly monitor infection and spread in experimental systems. To analyze real-time infection ...

XU L, Bao L, Yuan J, Li F, et al. Antigenicity and transmissibility of a new clade 2.3.2.1 avian influenza H5N1 virus. J Gen Virol. 2013 Sep 28.  Abstract  
submitted by kickingbird at Oct, 6, 2013 from J Gen Virol. 2013 Sep 28 (via http://www.ncbi.nlm.nih.gov/pubmed/24077367)
A genetic variant of the H5N1 virus, termed subclade 2.3.2.1, was first identified in Bulgaria in 2010 and has subsequently been found in Vietnam and Laos. Several cases of human infections with this virus ...

SUN Y, Jia T, Sun Y, Han Y, et al. External Quality Assessment for Avian Influenza A (H7N9) Virus Detection Using Armored RNA. J Clin Microbiol. 2013 Oct 2.  Abstract  
submitted by kickingbird at Oct, 6, 2013 from J Clin Microbiol. 2013 Oct 2 (via http://www.ncbi.nlm.nih.gov/pubmed/24088846)
An external quality assessment (EQA) program for molecular detection of avian influenza A (H7N9) virus was implemented by National Center for Clinical Laboratory (NCCL) of China during June 2013. Virus-like ...

ROUSSY JF, Abed Y, Bouhy X, Boivin G, et al. Emergence of an oseltamivir-resistant influenza A/H3N2 virus in an elderly receiving a suboptimal dose of antiviral prophylaxis.. J Clin Microbiol. 2013 Oct 2.  Abstract  
submitted by kickingbird at Oct, 6, 2013 from J Clin Microbiol. 2013 Oct 2 (via http://www.ncbi.nlm.nih.gov/pubmed/24088848)
We report on the emergence of an influenza A/H3N2-E119V neuraminidase variant from an elderly with renal dysfunction who received a suboptimal dose of oseltamivir prophylaxis. In neuraminidase inhibition ...

KHAN SU, Berman L, Haider N, Gerloff N, et al. Investigating a crow die-off in January-February 2011 during the introduction of a new clade of highly pathogenic avian influenza virus H5N1 into Bangladesh. Arch Virol. 2013 Oct 1.  Abstract  
submitted by kickingbird at Oct, 6, 2013 from Arch Virol. 2013 Oct 1 (via http://www.ncbi.nlm.nih.gov/pubmed/24081824)
We investigated unusual crow mortality in Bangladesh during January-February 2011 at two sites. Crows of two species, Corvus splendens and C. macrorhynchos, were found sick and dead during the outbreaks. ...

DOYLE TM, Hashem AM, Li C, Domselaar GV, et al. Universal Anti-Neuraminidase Antibody Inhibiting all Influenza A Subtypes. Antiviral Res. 2013 Sep 30.  Abstract  
submitted by kickingbird at Oct, 6, 2013 from Antiviral Res. 2013 Sep 30 (via http://www.ncbi.nlm.nih.gov/pubmed/24091204)
The only universally conserved sequence amongst all influenza A viral neuraminidase (NA) is located between amino acids 222-230 and plays crucial roles in viral replication. However, it remained unclear ...

GAVAZZI C, Yver M, Isel C, Smyth RP, et al. A functional sequence-specific interaction between influenza A virus genomic RNA segments. Proc Natl Acad Sci U S A. 2013 Sep 25..  Abstract  
submitted by kickingbird at Sep, 30, 2013 from Proc Natl Acad Sci U S A. 2013 Sep 25. (via http://www.pnas.org/content/early/2013/09/25/1314419110.abst)
Influenza A viruses cause annual influenza epidemics and occasional severe pandemics. Their genome is segmented into eight fragments, which offers evolutionary advantages but complicates genomic packaging. ...

ZHU X, Guo YH, Jiang T, Wang YD, et al. A Unique and Conserved Neutralization Epitope in H5N1 Influenza Viruses Identified by a Murine Antibody against the A/goose/Guangdong/1/96 Hemagglutinin. J Virol. 2013 Sep 18.  Abstract  
submitted by kickingbird at Sep, 30, 2013 from J Virol. 2013 Sep 18 (via http://www.ncbi.nlm.nih.gov/pubmed/24049169)
Despite substantial efforts to control and contain influenza H5N1 viruses, 'bird flu' viruses continue to spread and evolve. Neutralizing antibodies against conserved epitopes on the viral hemagglutinin ...

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