Wang Y, Li J, Yan W, Chen Q, Jiang Z, Zhang R. An active component containing pterodontic acid and pterodondiol isolated from Laggera pterodonta inhibits influenza A virus infection through the TLR7/MyD88/TRAF6/NF?κB signaling pathway. Mol Med Rep. 2018 May 2.. Abstract
submitted by kickingbird at May, 17, 2018 from Mol Med Rep. 2018 May 2. (via https://www.ncbi.nlm.nih.gov/pubmed/29749442)
The influenza virus is a pathogen that can cause pandemic and epidemic outbreaks, and therefore represents a severe threat to human health. Antiviral drugs have an important role in the prevention and ... Mandour YM, Breitinger U, Ma C, Wang J. Symmetric dimeric adamantanes for exploring the structure of two viroporins: influenza virus M2 and hepatitis C virus p7. Drug Des Devel Ther. 2018 Apr 30;12:1019-1031.. Abstract
submitted by kickingbird at May, 17, 2018 from Drug Des Devel Ther. 2018 Apr 30;12:1019-1031. (via https://www.ncbi.nlm.nih.gov/pubmed/29750015)
Background: Adamantane-based compounds have been identified to interfere with the ion-channel activity of viroporins and thereby inhibit viral infection. To better understand the difference in the inhibition ... Wang TT, Bournazos S, Ravetch JV. Immunological responses to influenza vaccination: lessons for improving vaccine efficacy. Curr Opin Immunol. 2018 May 10;53:124-129. Abstract
submitted by kickingbird at May, 17, 2018 from Curr Opin Immunol. 2018 May 10;53:124-129 (via https://www.ncbi.nlm.nih.gov/pubmed/29753885)
A critical factor in the maturation of influenza vaccine responses is the nearly inevitable binding of vaccine antigens by exiting anti-influenza IgGs. These antigen-IgG immune complexes direct the response ... Rudneva IA, Timofeeva TA, Mukasheva EA. Pleiotropic effects of hemagglutinin amino acid substitutions of influenza A(H1N1)pdm09 virus escape mutants. Virus Res. 2018 May 10. Abstract
submitted by kickingbird at May, 17, 2018 from Virus Res. 2018 May 10 (via https://www.ncbi.nlm.nih.gov/pubmed/29753891)
In the present study we assessed pleiotropic characteristics of the antibody-selected mutations. We investigated pH optimum of fusion, temperatures of HA heat inactivation, in vivo and in vitro replication ... Shanks GD, Wilson N, Kippen R, Brundage JF. The unusually diverse mortality patterns in the Pacific region during the 1918-21 influenza pandemic: reflections at the pandemic´s centenary. Lancet Infect Dis. 2018 May 10. Abstract
submitted by kickingbird at May, 17, 2018 from Lancet Infect Dis. 2018 May 10 (via https://www.ncbi.nlm.nih.gov/pubmed/29754745)
The 1918-21 influenza pandemic was the most lethal natural event in recent history. In the Pacific region, the pandemic's effects varied greatly across different populations and settings. In this region, ... Onozuka D, Hagihara A. Extreme influenza epidemics and out-of-hospital cardiac arrest. Int J Cardiol. 2018 Jul 15;263:158-162.. Abstract
submitted by kickingbird at May, 17, 2018 from Int J Cardiol. 2018 Jul 15;263:158-162. (via https://www.ncbi.nlm.nih.gov/pubmed/29754914)
INTRODUCTION: There is compelling evidence for an association between influenza epidemics and major adverse cardiovascular events. However, the role of extreme influenza epidemics as a trigger of out-of-hospital ... Spence KL, O´Sullivan TL, Poljak Z, Greer AL. Using a computer simulation model to examine the impact of biosecurity measures during a facility-level outbreak of equine influenza. Can J Vet Res. 2018 Apr;82(2):89-96.. Abstract
submitted by kickingbird at May, 17, 2018 from Can J Vet Res. 2018 Apr;82(2):89-96. (via https://www.ncbi.nlm.nih.gov/pubmed/29755187)
On-farm biosecurity measures are an important part of a control plan to minimize the introduction and spread of infectious diseases, such as equine influenza, in an equine facility. It can be challenging, ... Jegede A, Fu Q, Berhane Y, Lin M, Kumar A. H9N2 avian influenza virus retained low pathogenicity after serial passage in chickens. Can J Vet Res. 2018 Apr;82(2):131-138. Abstract
submitted by kickingbird at May, 17, 2018 from Can J Vet Res. 2018 Apr;82(2):131-138 (via https://www.ncbi.nlm.nih.gov/pubmed/29755193)
The H9N2 strains of avian influenza viruses (AIVs) circulate worldwide in poultry and cause sporadic infection in humans. To better understand the evolution of these viruses while circulating in poultry, ... Harrison SM, Wei MY, Lamerato LE, Petrie JG. Multimorbidity is associated with uptake of influenza vaccination. Vaccine. 2018 May 7.. Abstract
submitted by kickingbird at May, 17, 2018 from Vaccine. 2018 May 7. (via https://www.ncbi.nlm.nih.gov/pubmed/29748031)
OBJECTIVE: Patients with chronic conditions have higher rates of severe influenza-related illness and mortality. However, influenza vaccination coverage in high-risk populations continues to be suboptimal. ... Brown Jordan A, Narang D, Essen SC, Brookes SM. Serological Evidence for Influenza A Virus Exposure in Wild Birds in Trinidad & Tobago. Vet Sci. 2018 May 9;5(2).. Abstract
submitted by kickingbird at May, 17, 2018 from Vet Sci. 2018 May 9;5(2). (via https://www.ncbi.nlm.nih.gov/pubmed/29747454)
Migratory waterfowl and shorebirds are known to be important reservoirs for influenza A viruses (IAV) and they have been repeatedly implicated as causing avian influenza virus (AIV) outbreaks in domestic ... Lee S, Hirohama M, Noguchi M, Nagata K, Kawaguchi. Influenza A virus infection triggers pyroptosis and apoptosis of respiratory epithelial cells through type I IFN signaling pathway in a mutually exclusive manner. J Virol. 2018 May 9. Abstract
submitted by kickingbird at May, 14, 2018 from J Virol. 2018 May 9 (via https://www.ncbi.nlm.nih.gov/pubmed/29743359)
Respiratory epithelial cell death by influenza virus infection is responsible for induction of inflammatory responses, but the exact cell death mechanism is not understood. Here we showed that influenza ... Lin J, Xia J, Zhang T, Zhang K, Yang Q. Genome-wide profiling of microRNAs reveals novel insights into the interactions between H9N2 avian influenza virus and avian dendritic cells. Oncogene. 2018 May 10. Abstract
submitted by kickingbird at May, 14, 2018 from Oncogene. 2018 May 10 (via https://www.ncbi.nlm.nih.gov/pubmed/29743596)
The antigen-presenting ability of dendritic cells (DCs) plays an important and irreplaceable role in recognising and clearing viruses. Antiviral responses must rapidly defend against infection while minimising ... Wang YF, Chang CF, Tsai HP, etc.,al. Glycan-binding preferences and genetic evolution of human seasonal influenza A(H3N2) viruses during 1999~2007 in Taiwan. PLoS One. 2018 May 10;13(5):e0196727.. Abstract
submitted by kickingbird at May, 14, 2018 from PLoS One. 2018 May 10;13(5):e0196727. (via https://www.ncbi.nlm.nih.gov/pubmed/29746492)
It is generally agreed that human influenza virus preferentially binds to α-2,6-linked sialic acid-containing receptors, and mutations that change the binding preference may alter virus infectivity and ... Howard A, Uyeki TM, Fergie J. Influenza-Associated Acute Necrotizing Encephalopathy in Siblings. J Pediatric Infect Dis Soc. 2018 May 4.. Abstract
submitted by kickingbird at May, 14, 2018 from J Pediatric Infect Dis Soc. 2018 May 4. (via https://www.ncbi.nlm.nih.gov/pubmed/29741717)
Encephalopathy is an important complication associated with influenza, most frequently observed in young children, with a wide range of severity. The most severe category of influenza-associated encephalopathy ... Yamaguchi E, Fujii K, Ogawa H, Imai K. First detection of influenza A virus genes from wild raccoons in Japan. Virus Genes. 2018 May 8.. Abstract
submitted by kickingbird at May, 14, 2018 from Virus Genes. 2018 May 8. (via https://www.ncbi.nlm.nih.gov/pubmed/29740778)
Serological surveys have shown that wild raccoons are exposed to influenza A viruses (IAVs); however, no genetic evidence for this IAV infection has been found. In the present study, we first detected ... Koliopoulos MG, etc.,al. Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition. Nat Commun. 2018 May 8;9(1):1820.. Abstract
submitted by kickingbird at May, 14, 2018 from Nat Commun. 2018 May 8;9(1):1820. (via https://www.ncbi.nlm.nih.gov/pubmed/29739942)
RIG-I is a viral RNA sensor that induces the production of type I interferon (IFN) in response to infection with a variety of viruses. Modification of RIG-I with K63-linked poly-ubiquitin chains, synthesised ... Wang J, Su N, Dong Z, Liu C, Cui P, Huang JA. The Fifth Influenza A(H7N9) Epidemic: A Family Cluster of Infection in Suzhou City of China, 2016. Int J Infect Dis. 2018 May 5.. Abstract
submitted by kickingbird at May, 14, 2018 from Int J Infect Dis. 2018 May 5. (via https://www.ncbi.nlm.nih.gov/pubmed/29738825)
OBJECTIVE: Influenza A(H7N9) virus is known for its high pathogenicity in human. A family cluster of influenza A(H7N9) virus infection was identified in Suzhou, China. This study aimed to investigate the ... Chen L, Xing C, Ma G, Luo J, et al.. N-Myc Downstream-Regulated Gene 1 Facilitates Influenza A Virus Replication by Suppressing Canonical NF-κB Signaling. Virus Res 2018 May 3. Abstract
submitted by kickingbird at May, 14, 2018 from Virus Res 2018 May 3 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29730307/)
The highly pathogenic avian influenza (HPAI) A/H5N1 virus hijacks host cellular machinery to complete its life cycle; identification of the host factors involved in viral replication may facilitate antiviral ... Chan KF, Carolan LA, Korenkov D, Druce J, et al. Investigating Viral Interference Between Influenza A Virus and Human Respiratory Syncytial Virus in a Ferret Model of Infection. J Infect Dis 2018 May 8. Abstract
submitted by kickingbird at May, 14, 2018 from J Infect Dis 2018 May 8 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29746640/)
Epidemiological studies have observed that the seasonal peak incidence of influenza virus infection is sometimes separate from the peak incidence of human respiratory syncytial virus (hRSV) infection, ... Lee ACY, To KKW, Zhang AJX, Zhu H, et al.. Triple combination of FDA-approved drugs including flufenamic acid, clarithromycin and zanamivir improves survival of severe influenza in mice. Arch Virol 2018 May 7. Abstract
submitted by kickingbird at May, 14, 2018 from Arch Virol 2018 May 7 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29736671/)
Seasonal influenza virus remains a common cause of mortality despite the use of neuraminidase inhibitors. This study evaluated the efficacy of a triple combination of zanamivir, clarithromycin and flufenamic ... 8181 items, 20/Page, Page[245/410][|<<] [|<] [241] [242] [243] [244] [245] [246] [247] [248] [249] [250] [>|] [>>|] |
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