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2024-4-25 15:24:00
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MOSTAFA A, Kanrai P, Ziebuhr J, Pleschka S, et al. The PB1 segment of an influenza A virus H1N1 2009pdm isolate enhances the replication efficiency of specific influenza vaccine strains in cell culture and embryonated eggs. J Gen Virol. 2016 Jan 7. doi: 10.1099/jgv.0.000390.  Abstract  
submitted by kickingbird at Jan, 17, 2016 from J Gen Virol. 2016 Jan 7. doi: 10.1099/jgv.0.000390 (via http://www.ncbi.nlm.nih.gov/pubmed/26743314)
Influenza vaccine strains (IVS) contain the hemagglutinin (HA) and neuraminidase (NA) genome segments of relevant circulating strains in the genetic background of influenza A/PR/8/1934 virus (PR8). Previous ...

CHEN LJ, Lin XD, Guo WP, Tian JH, et al. Diversity and evolution of avian influenza viruses in live poultry markets, free range poultry and wild wetland birds in China. J Gen Virol. 2016 Jan 12. doi: 10.1099/.  Abstract  
submitted by kickingbird at Jan, 17, 2016 from J Gen Virol. 2016 Jan 12. doi: 10.1099/ (via http://www.ncbi.nlm.nih.gov/pubmed/26758561)
The wide circulation of novel avian influenza viruses (AIVs) highlights the risk of pandemic influenza emergence in China. To investigate the prevalence and genetic diversity of AIVs in different ecological ...

ZHANG J, Zhang Z, Fan HY, Zhang J, et al. Recombinant baculovirus vaccine containing multiple M2e and adjuvant LTB induces T cell dependent, cross-clade protection against H5N1 influenza virus in mice. Vaccine. 2015 Dec 23.  Abstract  
submitted by kickingbird at Jan, 10, 2016 from Vaccine. 2015 Dec 23 (via http://www.amedeo.com/p2.php?id=26724200&s=flu&pm=6213b1b427)
H5N1, highly pathogenic avian influenza poses, a threat to animal and human health. Rapid changes in H5N1 viruses require periodic reformulation of the conventional strain-matched vaccines, thus emphasizing ...

THARAKARAMAN K, Subramanian V, Viswanathan K, Sloa. A broadly neutralizing human monoclonal antibody is effective against H7N9. Proc Natl Acad Sci U S A. 2015 Sep 1;.  Abstract  
submitted by kickingbird at Jan, 10, 2016 from Proc Natl Acad Sci U S A. 2015 Sep 1; (via http://www.ncbi.nlm.nih.gov/pubmed/26283346)
Emerging strains of influenza represent a significant public health threat with potential pandemic consequences. Of particular concern are the recently emerged H7N9 strains which cause pneumonia with acute ...

DINIS JM, Florek NW, Fatola OO, Moncla LH, et al. Deep sequencing reveals potential antigenic variants at low frequency in influenza A-infected humans. J Virol. 2016 Jan 6..  Abstract  
submitted by kickingbird at Jan, 10, 2016 from J Virol. 2016 Jan 6. (via http://www.ncbi.nlm.nih.gov/pubmed/26739054)
Influenza vaccines must be frequently reformulated to account for antigenic changes in the viral envelope protein, hemagglutinin (HA). The rapid evolution of influenza virus under immune pressure is likely ...

CHEN D, Wen X, Sun Y, Mao H, et al. Multiple viral introductions: molecular characterization of influenza B virus in Wenzhou, Zhejiang, China, from 2011 to 2014 based on hemagglutinin and neuraminidase genes. Arch Virol. 2016 Jan 2..  Abstract  
submitted by kickingbird at Jan, 10, 2016 from Arch Virol. 2016 Jan 2. (via http://www.ncbi.nlm.nih.gov/pubmed/26724821)
Influenza B virus is a major causative agent of respiratory disease in humans. Our study of an outbreak of influenza B virus in Wenzhou from 2011 to 2014 revealed that 163 (5.58 %) of 2921 samples ...

WEI YR, Yang XY, Li YG, Wei J, et al. Serological survey of avian influenza virus infection in non-avian wildlife in Xinjiang, China. Arch Virol. 2016 Jan 5.  Abstract  
submitted by kickingbird at Jan, 10, 2016 from Arch Virol. 2016 Jan 5 (via http://www.ncbi.nlm.nih.gov/pubmed/26733295)
We conducted a serological survey to detect antibodies against avian influenza virus (AIV) in Gazella subgutturosa, Canis lupus, Capreolus pygargus, Sus scrofa, Cervus elaphus, Capra ibex, Ovis ammon, ...

LLM Poon, T Song, R Rosenfeld, etc.,al. Quantifying influenza virus diversity and transmission in humans. Nature Genetics (2016)doi:10.1038/ng.3479.  Abstract  
submitted by kickingbird at Jan, 9, 2016 from Nature Genetics (2016)doi:10.1038/ng.3479 (via http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3479.)
Influenza A virus is characterized by high genetic diversity. However, most of what is known about influenza evolution has come from consensus sequences sampled at the epidemiological scale that only represent ...

WANG L, Wu A, Wang YE, Quanquin N, et al. Functional Genomics Reveals Linkers Critical for Influenza Polymerase. J Virol. 2015 Dec 30. pii: JVI.02400.  Abstract  
submitted by kickingbird at Jan, 3, 2016 from J Virol. 2015 Dec 30. pii: JVI.02400 (via http://www.ncbi.nlm.nih.gov/pubmed/26719244)
Influenza virus mRNA synthesis by the RNA-dependent RNA polymerase involves binding and cleavage of capped cellular mRNA by the PB2 and PA subunits, respectively, and extension of viral mRNA by PB1. However, ...

NACHBAGAUER R, Miller MS, Hai R, Ryder AB, et al. Hemagglutinin stalk immunity reduces influenza virus replication and transmission in ferrets. J Virol. 2015 Dec 30. pii: JVI.02481-15..  Abstract  
submitted by kickingbird at Jan, 3, 2016 from J Virol. 2015 Dec 30. pii: JVI.02481-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26719251)
We assessed in ferrets whether influenza virus hemagglutinin stalk-based immunity provided protection against aerosol-transmitted H1N1 infection. Immunization of ferrets with a universal influenza virus ...

CAROLAN LA, Rockman S, Borg K, Guarnaccia T, et al. Characterisation of the localised immune response in the respiratory tract of ferrets following infection with influenza A and B viruses. J Virol. 2015 Dec 30. pii: JVI.02797-15.  Abstract  
submitted by kickingbird at Jan, 3, 2016 from J Virol. 2015 Dec 30. pii: JVI.02797-15 (via http://www.ncbi.nlm.nih.gov/pubmed/26719259)
The burden of infection with seasonal influenza viruses is significant. Each year is typically characterised by the dominance of one (sub)type or lineage of influenza A or B virus, respectively. The incidence ...

HANSON A, Imai M, Hatta M, McBride R, et al. Identification of Stabilizing Mutations in an H5 HA Influenza Virus Protein. J Virol. 2015 Dec 30. pii: JVI.02790.  Abstract  
submitted by kickingbird at Jan, 3, 2016 from J Virol. 2015 Dec 30. pii: JVI.02790 (via http://www.ncbi.nlm.nih.gov/pubmed/26719265)
Highly pathogenic avian influenza viruses of the H5N1 subtype continue to circulate in poultry in Asia, Africa, and the Middle East. Recently, outbreaks of novel reassortant H5 viruses have also occurred ...

CHIN AW, Yen HL, Krauss S, Webby RJ, et al. Recombinant influenza virus with a pandemic H2N2 polymerase complex has a higher adaptive potential than one with seasonal H2N2 polymerase complex. J Gen Virol. 2015 Dec 24. doi: 10.1099.  Abstract  
submitted by kickingbird at Jan, 3, 2016 from J Gen Virol. 2015 Dec 24. doi: 10.1099 (via http://www.ncbi.nlm.nih.gov/pubmed/26703222)
The reassortment of influenza viral gene segments plays a key role in the genesis of pandemic strains. All of the last three pandemic viruses contained reassorted polymerase complexes with subunits derived ...

ELDERFIELD RA, Koutsakos M, Frise R, Bradley K, et. NB protein does not affect Influenza B virus replication in vitro and is not required for replication in or transmission between ferrets. J Gen Virol. 2015 Dec 24. doi: 10.1099/.  Abstract  
submitted by kickingbird at Jan, 3, 2016 from J Gen Virol. 2015 Dec 24. doi: 10.1099/ (via http://www.ncbi.nlm.nih.gov/pubmed/26703440)
The influenza B virus encodes a unique protein, NB, a membrane protein whose function in the replication cycle is not, as yet, understood. We engineered a recombinant influenza B virus lacking NB expression ...

H. Yang, etc.,al. Prevalence, genetics, and transmissibility in ferrets of Eurasian avian-like H1N1 swine influenza viruses. PNAS December 28, 2015.  Abstract  
submitted by kickingbird at Dec, 29, 2015 from PNAS December 28, 2015 (via http://www.pnas.org/content/early/2015/12/23/1522643113.abst)
Pigs are important intermediate hosts for generating novel influenza viruses. The Eurasian avian-like H1N1 (EAH1N1) swine influenza viruses (SIVs) have circulated in pigs since 1979, and human cases associated ...

WU H, Peng X, Peng X, Cheng L, et al. Multiple amino acid substitutions involved in the adaptation of avian-origin influenza A (H10N7) virus in mice.. Arch Virol. 2015 Dec 23.  Abstract  
submitted by kickingbird at Dec, 27, 2015 from Arch Virol. 2015 Dec 23 (via http://www.ncbi.nlm.nih.gov/pubmed/26699787)
To identify substitutions that are possibly associated with the adaptation of avian-origin H10N7 virus to mammals, adaptation of the H10N7 virus in mouse lung was carried out by serial lung-to-lung passage. ...

Xianfeng Zhou; Wen Xia; Enjie Lu; Xiansheng Ni; Ku. Dynamic profiles of antibody response to H7N9 infection in five patients. Chinese Society for Immunology.  Abstract  
submitted by kickingbird at Dec, 25, 2015 from Chinese Society for Immunology (via http://www.cnki.net)
Background:Five human infections were caused by avian-origin influenza A(H7N9)virus in Nanchangcity during H7N9 outbreak in 2013.Objective:To understand the dynamic profiles of antibody response to H7Dynamicprofileso_省略_oninfivepatients_Xia.pdf

CHONG KC, Wang X, Liu S, Cai J, et al. Interpreting the transmissibility of the avian influenza A(H7N9) infection from 2013 to 2015 in Zhejiang Province, China. Epidemiol Infect. 2015 Dec 9:1-8..  Abstract  
submitted by kickingbird at Dec, 17, 2015 from Epidemiol Infect. 2015 Dec 9:1-8. (via http://www.ncbi.nlm.nih.gov/pubmed/26645357)
Three epidemic waves of human influenza A(H7N9) were documented in several different provinces in China between 2013 and 2015. With limited understanding of the potential for human-to-human transmission, ...

GAO R, Bai T, Li X, Xiong Y, et al. The comparison of pathology in ferrets infected by H9N2 avian influenza viruses with different genomic features. Virology. 2015;488:149-155.  Abstract  
submitted by kickingbird at Dec, 17, 2015 from Virology. 2015;488:149-155 (via http://www.ncbi.nlm.nih.gov/pubmed/26638019)
H9N2 avian influenza virus circulates widely in poultry and has been responsible for sporadic human infections in several regions. Few studies have been conducted on the pathogenicity of H9N2 AIV isolates ...

MUZYKA D, Pantin-Jackwood M, Starick E, Fereidouni. Evidence for genetic variation of Eurasian avian influenza viruses of subtype H15: the first report of an H15N7 virus. Arch Virol. 2015 Dec 9.  Abstract  
submitted by kickingbird at Dec, 17, 2015 from Arch Virol. 2015 Dec 9 (via http://www.ncbi.nlm.nih.gov/pubmed/26650037)
Since the first detection of H15 avian influenza viruses (AIVs) in Australia in 1979, only seven H15 strains have been reported. A new H15 AIV was detected in Ukraine in 2010, carrying the unique ...

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