de Vries RP, Peng W, Grant OC, Thompson AJ, Zhu X,. Three mutations switch H7N9 influenza to human-type receptor specificity. PLoS Pathog 13(6): e1006390.. Abstract
submitted by kickingbird at Jun, 16, 2017 from PLoS Pathog 13(6): e1006390. (via http://journals.plos.org/plospathogens/article?id=10.1371/jo)
The avian H7N9 influenza outbreak in 2013 resulted from an unprecedented incidence of influenza transmission to humans from infected poultry. The majority of human H7N9 isolates contained a hemagglutinin ... Ninpan K, Suptawiwat O, Boonarkart C, Songprakhon. Mutations in Matrix Protein 1 and Nucleoprotein caused Human-Specific Defects in Nuclear Exportation and Viral Assembly of an Avian Influenza H7N1 Virus. Virus Res 2017 Jun 1. Abstract
submitted by kickingbird at Jun, 13, 2017 from Virus Res 2017 Jun 1 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28579356/)
Nuclear exportation of influenza ribonucleoprotein is a vital step in viral replication cycle. In this study a particular H7N1 (A/ostrich/Zimbabwe/222-E3/1996) virus showed exclusively nuclear localization ... Manito ACB, Graf T, Lunge VR, Ikuta N, et al.. Spatiotemporal dynamics of influenza A(H1N1)pdm09 in Brazil during the pandemic and post-pandemic periods. Virus Res 2017 Jun 3. Abstract
submitted by kickingbird at Jun, 13, 2017 from Virus Res 2017 Jun 3 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28587867/)
Influenza A(H1N1)pdm09 was responsible for the first global flu pandemic in 21st century affecting all the world. In Brazil, A(H1N1)pdm09 is still circulating as a seasonal virus, causing deaths every ... Kurupati RK, Kossenkoff A, Kannan S, Haut LH, et a. The effect of timing of influenza vaccination and sample collection on antibody titers and responses in the aged. Vaccine 2017 Jun 2. Abstract
submitted by kickingbird at Jun, 13, 2017 from Vaccine 2017 Jun 2 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28583307/)
Antibody responses, B cell subset distribution in blood and the blood transcriptome were analyzed in younger and aged human subjects before and after vaccination with the inactivated influenza vaccine. ... Vijayan M, Xia C, Song YE, Ngo H, et al.. Sphingosine 1-Phosphate Lyase Enhances the Activation of IKKε To Promote Type I IFN-Mediated Innate Immune Responses to Influenza A Virus Infection. J Immunol 2017 Jun 9. Abstract
submitted by kickingbird at Jun, 13, 2017 from J Immunol 2017 Jun 9 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28600291/)
Sphingosine 1-phosphate (S1P) lyase (SPL) is an intracellular enzyme that mediates the irreversible degradation of the bioactive lipid S1P. We have previously reported that overexpressed SPL displays anti-influenza ... Naguib MM, Grund C, Arafa AS, Abdelwhab EM, et al. Heterologous post-infection immunity against Egyptian avian influenza virus (AIV) H9N2 modulates the course of subsequent infection by highly pathogenic AIV H5N1, but vaccination immunity does not. J Gen Virol 2017 Jun 5. Abstract
submitted by kickingbird at Jun, 13, 2017 from J Gen Virol 2017 Jun 5 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28590242/)
In Egypt, zoonotic A/goose/Guangdong/1/96 (gs/GD-like) highly pathogenic avian influenza virus (HPAIV) H5N1 of clade 2.2.1.2 is entrenched in poultry populations and has co-circulated with low-pathogenic ... Zhang X, Xu G, Wang C, Jiang M, et al.. Enhanced pathogenicity and neurotropism of mouse-adapted H10N7 influenza virus are mediated by novel PB2 and NA mutations. J Gen Virol 2017 Jun 8. Abstract
submitted by kickingbird at Jun, 13, 2017 from J Gen Virol 2017 Jun 8 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28597818/)
The H10 subtype of avian influenza viruses (AIVs) circulates globally in wild birds and poultry, and this subtype has been shown to be increasingly prevalent in China. Among the various H10 viruses, H10N7 ... Yamashita N, Yashiro M, Ogawa H, Namba H, et al. Metabolic pathway catalyzed by Vanin-1 pantetheinase plays a suppressive role in influenza virus replication in human alveolar epithelial A549 cells. Biochem Biophys Res Commun 2017 May 30. Abstract
submitted by kickingbird at Jun, 13, 2017 from Biochem Biophys Res Commun 2017 May 30 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28576495/)
Our previous analysis of gene expression profiles in the peripheral blood from patients with influenza A (H1N1) pdm09 pneumonia revealed elevated transcription levels of the vanin-1 (vascular non-inflammatory ... Zhang ZH, Meng LS, Kong DH, Liu J, Li SZ, Zhou C,. A Suspected Person-to-person Transmission of Avian Influenza A (H7N9) Case in Ward. Chin Med J 2017 Jun 6. Abstract
submitted by kickingbird at Jun, 7, 2017 from Chin Med J 2017 Jun 6 (via http://www.cmj.org/text.asp?2017/130/10/1255/205849)
Since throat swab specimens obtained from three adult Chinese patients were confirmed as an avian-origin influenza A (H7N9) virus by local Centers for Disease Control and Prevention (CDC) in 2013,[1] many ... X Wang, etc.,al. Epidemiology of avian influenza A H7N9 virus in human beings across five epidemics in mainland China, 2013~17: an epidemiological study of laboratory-confirmed case series. Lancet Infect Dis. Abstract
submitted by kickingbird at Jun, 6, 2017 from Lancet Infect Dis (via http://www.thelancet.com/journals/laninf/article/PIIS1473-30)
Summary
Background
The avian influenza A H7N9 virus has caused infections in human beings in China since 2013. A large epidemic in 2016–17 prompted concerns that the epidemiology of the virus might ... Wang BX, Brown EG, Fish EN. Residues F103 and M106 within the influenza A virus NS1 CPSF4-binding region regulate interferon-stimulated gene translation initiation. Virology 2017;508:170-179. Abstract
submitted by kickingbird at Jun, 5, 2017 from Virology 2017;508:170-179 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28554059/)
Influenza A virus (IAV) non-structural protein 1 (NS1) suppresses host innate immune responses by inhibiting type I interferon (IFN) production. We provide evidence that residues F103 and M106 in the CPSF4-binding ... Bertran K, Balzli C, Lee DH, Suarez DL, et al. Protection of White Leghorn chickens by U.S. emergency H5 vaccination against clade 2.3.4.4 H5N2 high pathogenicity avian influenza virus. Vaccine 2017 May 26. Abstract
submitted by kickingbird at Jun, 5, 2017 from Vaccine 2017 May 26 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28554502/)
During December 2014-June 2015, the U.S. experienced a high pathogenicity avian influenza (HPAI) outbreak caused by clade 2.3.4.4 H5Nx Goose/Guangdong lineage viruses with devastating consequences for ... Petiot E, Proust A, Traversier A, Durous L, et al. Influenza viruses production: Evaluation of a novel avian cell line DuckCelt-T17. Vaccine 2017 May 29. Abstract
submitted by kickingbird at Jun, 5, 2017 from Vaccine 2017 May 29 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28571695/)
The influenza vaccine manufacturing industry is looking for production cell lines that are easily scalable, highly permissive to multiple viruses, and more effective in term of viral productivity. One ... Yu Y, Zhang X, Zhao B, Sun Y, et al. A Sandwich ELISA for the Detection of Neuraminidase of Avian Influenza A(H7N9) Virus. J Virol Methods 2017 May 24.. Abstract
submitted by kickingbird at Jun, 5, 2017 from J Virol Methods 2017 May 24. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28551451/)
Although exhibiting no or low virulence in poultry, avian influenza virus H7N9 has caused around 1,200 confirmed human infections in China with a case-fatality rate of 30% since 2013. A highly pathogenic ... Granados A, Petrich A, McGeer A, Gubbay JB, et al. Measuring influenza RNA quantity after prolonged storage or multiple freeze/thaw cycles. J Virol Methods 2017;247:45-50. Abstract
submitted by kickingbird at Jun, 5, 2017 from J Virol Methods 2017;247:45-50 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28572040/)
In this study, we aim to determine what effects prolonged storage and repeated freeze/thaw cycles have on the stability of influenza A(H1N1)pdm09 (influenza A/H1N1)RNA. Cloned influenza A/H1N1 RNA transcripts ... Lee ACY, To KKW, Zhu H, Chu H, et al. Avian influenza virus A H7N9 infects multiple mononuclear cell types in peripheral blood and induces dysregulated cytokine responses and apoptosis in infected monocytes. J Gen Virol 2017 May 30. Abstract
submitted by kickingbird at Jun, 5, 2017 from J Gen Virol 2017 May 30 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28555541/)
Most patients with avian influenza A H7N9 virus (H7N9) infection suffer from severe illness, accompanied by dysregulated cytokine/chemokine response, delayed viral clearance and impaired neutralizing antibody ... Baratelli M, Pedersen LE, Trebbien R, Larsen LE, e. Identification of cross-reacting T-cell epitopes in structural and non-structural proteins of swine and pandemic H1N1 influenza A virus strains in pigs. J Gen Virol 2017 May 30. Abstract
submitted by kickingbird at Jun, 5, 2017 from J Gen Virol 2017 May 30 (via https://www.ncbi.nlm.nih.gov/m/pubmed/28555545/)
Heterologous protection against swine influenza viruses (SwIVs) of different lineages is an important concern for the pig industry. Cross-protection between 'avian-like' H1N1 and 2009 pandemic H1N1 lineages ... Giarola-Silva S, Coelho-Dos-Reis JGA, Mourao MM, C. Distinct patterns of cellular immune response elicited by influenza non-adjuvanted and AS03-adjuvanted monovalent H1N1(pdm09) vaccine. Antiviral Res 2017;144:70-82.. Abstract
submitted by kickingbird at Jun, 5, 2017 from Antiviral Res 2017;144:70-82. (via https://www.ncbi.nlm.nih.gov/m/pubmed/28549970/)
The study aimed at identifying biomarkers of immune response elicited by non-adjuvanted-(NAV) and adjuvanted-(AV) H1N1(pdm09) vaccines. The results showed that despite both vaccines elicited similar levels ... Ke C, Mok CKP, Zhu W, Zhou H, He J, Guan W, et al.. Human Infection with Highly Pathogenic Avian Influenza A(H7N9) Virus, China. Emerg Infect Dis. 2017 Aug. Abstract
submitted by kickingbird at Jun, 3, 2017 from Emerg Infect Dis. 2017 Aug (via https://wwwnc.cdc.gov/eid/article/23/8/17-0600_article)
The recent increase in zoonotic avian influenza A(H7N9) disease in China is a cause of public health concern. Most of the A(H7N9) viruses previously reported have been of low pathogenicity. We report the ... Zhou L, Tan Y, Kang M, Liu F, Ren R, Wang Y, et al. Preliminary Epidemiology of Human Infections with Highly Pathogenic Avian Influenza A(H7N9) Virus, China, 2017. Emerg Infect Dis. 2017 Aug. Abstract
submitted by kickingbird at Jun, 3, 2017 from Emerg Infect Dis. 2017 Aug (via https://wwwnc.cdc.gov/eid/article/23/8/17-0640_article)
We compared the characteristics of cases of highly pathogenic avian influenza (HPAI) and low pathogenic avian influenza (LPAI) A(H7N9) virus infections in China. HPAI A(H7N9) case-patients were more likely ... 7516 items, 20/Page, Page[231/376][|<<] [|<] [231] [232] [233] [234] [235] [236] [237] [238] [239] [240] [>|] [>>|] |
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