Timofeeva TA, Sadykova GK, Lomakina NF, Gambaryan. The Effect of I155T, K156Q, K156E and N186K Mutations in Hemagglutinin on the Virulence and Reproduction of Influenza A/H5N1 Viruses. Mol Biol. 2020;54(6):861-869. Abstract
submitted by kickingbird at Jan, 12, 2021 from Mol Biol. 2020;54(6):861-869 (via https://link.springer.com/article/10.1134/S0026893320060126)
The continued circulation of influenza A virus subtype H5 may cause the emergence of new potential pandemic virus variants, which can be transmitted from person to person. The occurrence of such variants ... An SH, Hong SM, Son SE, Song JH, Lee CY, Choi JG,. Improvement of PR8-Derived Recombinant Clade 2.3.4.4c H5N6 Vaccine Strains by Optimization of Internal Genes and H103Y Mutation of Hemagglutinin. Vaccines (Basel). 2020 Dec 20;8(4):E781. Abstract
submitted by kickingbird at Jan, 11, 2021 from Vaccines (Basel). 2020 Dec 20;8(4):E781 (via https://www.mdpi.com/2076-393X/8/4/781)
Clade 2.3.4.4c H5N6 avian influenza A viruses (AIVs) may have originally adapted to infect chickens and have caused highly pathogenic avian influenza (HPAI) in poultry and human fatalities. Although A/Puerto ... Schweitzer KS, Crue T, Nall JM, Foster D, Sajuthi. Influenza virus infection increases ACE2 expression and shedding in human small airway epithelial cells. Eur Respir J. 2021 Jan 8:2003988. Abstract
submitted by kickingbird at Jan, 11, 2021 from Eur Respir J. 2021 Jan 8:2003988 (via https://erj.ersjournals.com/content/early/2020/12/17/1399300)
Patients with COVID-19 caused by severe acute respiratory syndrome coronavirus (SARS-Co-V)-2 demonstrate high rates of co-infection with respiratory viruses, including influenza A (IAV), suggesting pathogenic ... Zhao D, Qiu D, Qi X, Li S, Zhao Y, Dong Y, Wen X,. Generation and properties of one strain of H3N2 influenza virus with enhanced replication. Vet Microbiol. 2020 Dec 28;253:108970. Abstract
submitted by kickingbird at Jan, 11, 2021 from Vet Microbiol. 2020 Dec 28;253:108970 (via https://www.sciencedirect.com/science/article/pii/S037811352)
H3N2 canine influenza virus (CIV) has been circulating in many countries since 2008. The epidemic spread of CIV could be a concern for public health because of the close contact between humans and companion ... Sano K, Saito S, Suzuki T, Kotani O, Ainai A, van. An influenza HA stalk reactive polymeric IgA antibody exhibits anti-viral function regulated by binary interaction between HA and the antibody. PLoS One. 2021 Jan 7;16(1):e0245244. Abstract
submitted by kickingbird at Jan, 10, 2021 from PLoS One. 2021 Jan 7;16(1):e0245244 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
IgA antibodies, which are secreted onto the mucosal surface as secretory IgA antibodies (SIgAs), play an important role in preventing influenza virus infection. A recent study reported that anti-hemagglutinin ... Wang Q, Sun Z, Li J, Qin T, Ma H, Chen S, Peng D,. Identification of a universal antigen epitope of influenza A virus using peptide microarray. BMC Vet Res. 2021 Jan 7;17(1):22. Abstract
submitted by kickingbird at Jan, 10, 2021 from BMC Vet Res. 2021 Jan 7;17(1):22 (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
Background: Hemagglutinin is a major surface protein in influenza A virus (IAV), and HA2 is relative conserved among different IAVs. It will be meaningful to identify broad-spectrum epitopes based on the ... Yamazaki T, Biswas M, Kosugi K, Nagashima M, Inui. A Novel Gene Delivery Vector of Agonistic Anti-Radioprotective 105 Expressed on Cell Membranes Shows Adjuvant Effect for DNA Immunization Against Influenza. Front Immunol. 2020 Dec 22;11:606518. Abstract
submitted by kickingbird at Jan, 10, 2021 from Front Immunol. 2020 Dec 22;11:606518 (via https://www.frontiersin.org/articles/10.3389/fimmu.2020.6065)
Radioprotective 105 (RP105) (also termed CD180) is an orphan and unconventional Toll-like receptor (TLR) that lacks an intracellular signaling domain. The agonistic anti-RP105 monoclonal antibody (mAb) ... Feng M, Zhang Q, Wu W, Chen L, Gu S, Ye Y, Zhong Y. Inducible Guanylate-Binding Protein 7 Facilitates Influenza A Virus Replication by Suppressing Innate Immunity via NF-κB and JAK-STAT Signaling Pathways. J Virol. 2021 Jan 6:JVI.02038-20. Abstract
submitted by kickingbird at Jan, 8, 2021 from J Virol. 2021 Jan 6:JVI.02038-20 (via https://jvi.asm.org/content/early/2021/01/05/JVI.02038-20)
Guanylate-binding protein 7 (GBP7) belongs to the GBP family, which plays key roles in mediating innate immune responses to intracellular pathogens. Thus far, GBP7 has been reported to be a critical cellular ... Patil A, Anhlan D, Ferrando V, Mecate-Zambrano A,. Phosphorylation of influenza A virus NS1 at serine 205 mediates its viral polymerase-enhancing function. J Virol. 2021 Jan 6:JVI.02369-20. Abstract
submitted by kickingbird at Jan, 8, 2021 from J Virol. 2021 Jan 6:JVI.02369-20 (via https://jvi.asm.org/content/early/2021/01/05/JVI.02369-20)
Influenza A virus (IAV) non-structural protein 1 (NS1) is a protein with multiple functions that are regulated by phosphorylation. Phospho-proteomic screening of H1N1-infected cells identified NS1 to be ... Zhang X, Pu J, Sun Y, Yuhai B, Jiang Z, Xu G, Zhan. Neurovirulence of avian influenza virus is dependent on the interaction of viral NP protein with host factor FMRP in the murine brain. J Virol. 2021 Jan 6:JVI.01272-20. Abstract
submitted by kickingbird at Jan, 8, 2021 from J Virol. 2021 Jan 6:JVI.01272-20 (via https://jvi.asm.org/content/early/2021/01/05/JVI.01272-20)
Avian influenza viruses (AIVs) are zoonotic viruses that exhibit a range infectivity and severity in the human host. Severe human cases of AIVs infection are often accompanied by neurological symptoms, ... Takayama I, Nguyen BG, Dao CX, Pham TT, Dang TQ, T. Next-Generation Sequencing Analysis of the Within-Host Genetic Diversity of Influenza A(H1N1)pdm09 Viruses in the Upper and Lower Respiratory Tracts of Patients with Severe Influenza. mSphere. 2021 Jan 6;6(1):e01043-20. Abstract
submitted by kickingbird at Jan, 8, 2021 from mSphere. 2021 Jan 6;6(1):e01043-20 (via https://msphere.asm.org/content/6/1/e01043-20)
The influenza A(H1N1)pdm09 virus emerged in April 2009 with an unusual incidence of severe disease and mortality, and currently circulates as a seasonal influenza virus. Previous studies using consensus ... Gong W, Huang K, Zhang Y, He X, Li C, Mao H, Wei Y. Transcriptome Profiles of Highly Pathogenic Pure Avian H7N9 Virus-Infected Lungs of BALB/c Mice. Front Vet Sci. 2020 Dec 21;7:603584. Abstract
submitted by kickingbird at Jan, 8, 2021 from Front Vet Sci. 2020 Dec 21;7:603584 (via https://www.frontiersin.org/articles/10.3389/fvets.2020.6035)
Avian influenza A (H7N9) viruses emerged in China in 2013 and caused a zoonotic disease associated with a high case-fatality ratio of more than 30%. Transcriptional profiles obtained using animal models ... Lewis NS, Banyard AC, Whittard E, Karibayev T, Kaf. Emergence and spread of novel H5N8, H5N5 and H5N1 clade 2.3.4.4 highly pathogenic avian influenza in 2020. Emerg Microbes Infect. 2021 Jan 5:1-10. Abstract
submitted by kickingbird at Jan, 6, 2021 from Emerg Microbes Infect. 2021 Jan 5:1-10 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2021.1)
Analyses of HPAI H5 viruses from poultry outbreaks across a wide Eurasian region since July 2020 including the Russian Federation, Republics of Iraq and Kazakhstan, and recent detections in migratory waterfowl ... Gravenstein S, McConeghy KW, Saade E, Davidson HE,. Adjuvanted influenza vaccine and influenza outbreaks in U.S. nursing homes: Results from a pragmatic cluster-randomized clinical trial. Clin Infect Dis. 2021 Jan 5:ciaa1916. Abstract
submitted by kickingbird at Jan, 6, 2021 from Clin Infect Dis. 2021 Jan 5:ciaa1916 (via https://pubmed.ncbi.nlm.nih.gov/33400778/)
Background: Influenza outbreaks in nursing homes pose a threat to frail residents and occur even in vaccinated populations. We conducted a pragmatic cluster-randomized trial comparing adjuvanted trivalent ... Boikos C, Fischer L, O´Brien D, Vasey J, Syl. Relative Effectiveness of the Cell-Derived Inactivated Quadrivalent Influenza Vaccine Versus Egg-Derived Inactivated Quadrivalent Influenza Vaccines in Preventing Influenza-Related Medical Encounters. Clin Infect Dis. 2021 Jan 5:ciaa1944. Abstract
submitted by kickingbird at Jan, 6, 2021 from Clin Infect Dis. 2021 Jan 5:ciaa1944 (via https://pubmed.ncbi.nlm.nih.gov/33400775/)
Background: The cell-propagated inactivated quadrivalent influenza vaccine (ccIIV4) may offer improved protection in seasons where egg-derived influenza viruses undergo mutations that affect antigenicity. ... Lambrou AS, Luitel H, Bhattarai RK, Basnet HB, Hea. Informing influenza pandemic preparedness using commercial poultry farmer knowledge, attitudes, and practices (KAP) surrounding biosecurity and self-reported avian influenza outbreaks in Nepal. One Health. 2020 Oct 23;11:100189. Abstract
submitted by kickingbird at Jan, 5, 2021 from One Health. 2020 Oct 23;11:100189 (via https://www.sciencedirect.com/science/article/pii/S235277142)
Avian influenza (AI) is a global health obstacle of critical concern as novel viruses are capable of initiating a pandemic. Recent spillover events of AI into human populations have occurred at human-poultry ... Damjanovska S, Smith C, Sayin I, Burant CJ, Graven. Adjuvant effect of type I interferon induced by many but not all commercial influenza vaccines. Vaccine. 2020 Dec 31:S0264-410X(20)31631-5. Abstract
submitted by kickingbird at Jan, 4, 2021 from Vaccine. 2020 Dec 31:S0264-410X(20)31631-5 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Background: Seasonal influenza vaccines approved and offered in the United States have varying reported degrees of effectiveness year over year and between manufacturers. Influenza vaccines produced from ... Liu Y, Li S, Sun H, Pan L, Cui X, Zhu X, Feng Y, L. Variation and Molecular Basis for Enhancement of Receptor Binding of H9N2 Avian Influenza Viruses in China Isolates. Front Microbiol. 2020 Dec 17;11:602124. Abstract
submitted by kickingbird at Jan, 4, 2021 from Front Microbiol. 2020 Dec 17;11:602124 (via https://pubmed.ncbi.nlm.nih.gov/33391219/)
Currently, H9N2 avian influenza viruses (H9N2 AIVs) globally circulate in poultry and have acquired some adaptation to mammals. However, it is not clear what the molecular basis is for the variation in ... Bai R, Sikkema RS, Munnink BBO, Li CR, Wu J, Zou L. Exploring utility of genomic epidemiology to trace origins of highly pathogenic influenza A/H7N9 in Guangdong. Virus Evol. 2020 Dec 18;6(2):veaa097. Abstract
submitted by kickingbird at Jan, 4, 2021 from Virus Evol. 2020 Dec 18;6(2):veaa097 (via https://academic.oup.com/ve/article/6/2/veaa097/6041617)
The first highly pathogenic (HP) influenza A/H7N9 was reported in Guangdong in January 2017. To investigate the emergence and spread of HP A/H7N9 in Guangdong province, we sequenced 297 viruses (58 HP ... Anjorin AA, Adepoju BA. Serologic evidence of seasonal influenza A and B in HIV patients on combined antiretroviral therapy in Lagos, Nigeria. Afr J Lab Med. 2020 Dec 21;9(1):1048. Abstract
submitted by kickingbird at Jan, 4, 2021 from Afr J Lab Med. 2020 Dec 21;9(1):1048 (via https://ajlmonline.org/index.php/AJLM/article/view/1048)
Background: Influenza and HIV are endemic in Nigeria but there is no epidemiological data on the co-infection of influenza A and B among HIV patients.Objective: We investigated seasonal influenza A and ... 8181 items, 20/Page, Page[134/410][|<<] [|<] [131] [132] [133] [134] [135] [136] [137] [138] [139] [140] [>|] [>>|] |
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