CHAKRABARTI AK, Pasricha G.. An insight into the PB1F2 protein and its multifunctional role in enhancing the pathogenicity of the influenza A viruses. Virology. 2013 Mar 29. pii: S0042-6822(13)00130. Abstract
submitted by kickingbird at Apr, 7, 2013 from Virology. 2013 Mar 29. pii: S0042-6822(13)00130 (via http://www.ncbi.nlm.nih.gov/pubmed/23545143)
PB1F2 is the 11th protein of the influenza A virus. The protein has variable sizes with truncations either at the C- or N-terminal ends. The most recent example being the 2009 pandemic H1N1 virus which ... Wang S, Zhao Z, Bi Y, Sun L, et al.. Tyrosine 132 phosphorylation of influenza A virus M1 protein is crucial for virus replication by controlling its nuclear import. J Virol 2013. Abstract
submitted by kickingbird at Apr, 1, 2013 from J Virol 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/23536660/)
Phosphorylation of viral protein plays important roles in the influenza A virus (IAV) life cycle. By using mass spectrometry, we have identified tyrosine (Y) 132 as a phosphorylation site of matrix protein ... Martinez-Romero C, de Vries E, Belicha-Villanueva. Substitutions T200A and E227A in the hemagglutinin of pandemic 2009 influenza A virus increase lethality but decrease transmission. J Virol 2013. Abstract
submitted by kickingbird at Apr, 1, 2013 from J Virol 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/23536663/)
We describe that swine influenza virus-like substitutions T200A and E227A in the hemagglutinin of the 2009 pandemic influenza virus alter its pathogenesis and transmission. Viral replication is increased ... Graham AC, Hilmer KM, Zickovich JM, Obar JJ, et al. Inflammatory Response of Mast Cells during Influenza A Virus Infection Is Mediated by Active Infection and RIG-I Signaling. J Immunol 2013.. Abstract
submitted by kickingbird at Apr, 1, 2013 from J Immunol 2013. (via http://www.ncbi.nlm.nih.gov/m/pubmed/23526820/)
Influenza A virus (IAV) is a major respiratory pathogen of both humans and animals. The lung is protected from pathogens by alveolar epithelial cells, tissue-resident alveolar macrophages, dendritic cells, ... Lee YN, Youn HN, Kwon JH, Lee DH, et al. Sublingual administration of Lactobacillus rhamnosus affects respiratory immune responses and facilitates protection against influenza virus infection in mice. Antiviral Res 2013 Mar 20. pii: S0166-3542(13)0006. Abstract
submitted by kickingbird at Apr, 1, 2013 from Antiviral Res 2013 Mar 20. pii: S0166-3542(13)0006 (via http://www.ncbi.nlm.nih.gov/m/pubmed/23523767/)
The extensive morbidity and mortality caused by influenza A viruses worldwide prompts the need for a deeper understanding of the host immune response and novel therapeutic and/or prophylactic interventions. ... Samson M, Pizzorno A, Abed Y, Boivin G, et al.. Influenza Virus Resistance to Neuraminidase Inhibitors. Antiviral Res 2013 Mar 21. pii: S0166-3542(13)0006. Abstract
submitted by kickingbird at Apr, 1, 2013 from Antiviral Res 2013 Mar 21. pii: S0166-3542(13)0006 (via http://www.ncbi.nlm.nih.gov/m/pubmed/23523943/)
In addition to immunization programs, antiviral agents can play a major role for the control of seasonal influenza epidemics and may also provide prophylactic and therapeutic benefits during an eventual ... Bertran K, Pérez-Ramírez E, Busquets N, Dolz R, Ra. Pathogenesis and transmissibility of highly (H7N1) and low (H7N9) pathogenic avian influenza virus infection in red-legged partridge (Alectoris rufa).. Vet Res. 2011 Feb 7;42(1):24. doi: 10.1186/1297-97. Abstract
submitted by kickingbird at Mar, 31, 2013 from Vet Res. 2011 Feb 7;42(1):24. doi: 10.1186/1297-97 (via http://www.ncbi.nlm.nih.gov/pubmed/21314907)
An experimental infection with highly pathogenic avian influenza virus (HPAIV) and low pathogenic avian influenza virus (LPAIV) was carried out in red-legged partridges (Alectoris rufa) in order to study ... Pérez-Ramírez E, Gerrikagoitia X, Barral M, H?fle. Detection of low pathogenic avian influenza viruses in wild birds in Castilla-La Mancha (south central Spain).. Vet Microbiol. 2010 Dec 15;146(3-4):200-8. doi: 10. Abstract
submitted by kickingbird at Mar, 31, 2013 from Vet Microbiol. 2010 Dec 15;146(3-4):200-8. doi: 10 (via http://www.ncbi.nlm.nih.gov/pubmed/20605691)
The Iberian Peninsula is located along the East Atlantic and Black Sea/Mediterranean flyways and is the third ranking European country as wintering quarter for wild migrating birds after Turkey and Rumania. ... HARRIS AK, Meyerson JR, Matsuoka Y, Kuybeda O, et. Structure and accessibility of HA trimers on intact 2009 H1N1 pandemic influenza virus to stem region-specific neutralizing antibodies. Proc Natl Acad Sci U S A. 2013 Mar 4. Abstract
submitted by kickingbird at Mar, 10, 2013 from Proc Natl Acad Sci U S A. 2013 Mar 4 (via http://www.ncbi.nlm.nih.gov/pubmed/23460696)
Rapid antigenic variation of HA, the major virion surface protein of influenza A virus, remains the principal challenge to the development of broader and more effective vaccines. Some regions of HA, such ... SANTOS A, Pal S, Chacon J, Meraz K, et al. SUMOylation affects the interferon blocking activity of the influenza A non-structural protein NS1 without affecting its stability or cellular localization. J Virol. 2013 Mar 6. Abstract
submitted by kickingbird at Mar, 10, 2013 from J Virol. 2013 Mar 6 (via http://www.ncbi.nlm.nih.gov/pubmed/23468495)
Our pioneering studies on the interplay between the Small Ubiquitin-like MOdifier (SUMO) and influenza A virus identified the non-structural NS1 protein as the first known SUMO target of influenza virus ... PETERSEN H, Wang Z, Lenz E, Pleschka S, et al. Reassortment of NS-segments modifies highly-pathogenic avian influenza virus interaction with avian hosts and host cells. J Virol. 2013 Mar 6. Abstract
submitted by kickingbird at Mar, 10, 2013 from J Virol. 2013 Mar 6 (via http://www.ncbi.nlm.nih.gov/pubmed/23468508)
Highly pathogenic avian influenza viruses (HPAIV) of subtypes H5 and H7 have caused numerous outbreaks in diverse poultry species and rising numbers of human infections. Both HPAIV subtypes support a growing ... Fontana J, Steven AC.. At low pH, Influenza virus matrix protein M1 undergoes a conformational change prior to dissociating from the membrane. J Virol. 2013 Mar 6. Abstract
submitted by kickingbird at Mar, 10, 2013 from J Virol. 2013 Mar 6 (via http://www.ncbi.nlm.nih.gov/pubmed/23468509)
The M1 matrix protein of influenza A virus, which plays multiple roles in virion assembly and infection, underlies the viral envelope. However, previous studies have given differing accounts of the number ... GOVORKOVA EA, Baranovich T, Seiler P, Armstrong J,. Antiviral resistance among highly pathogenic influenza A (H5N1) viruses isolated worldwide in 2002-2012 shows need for continued monitoring. Antiviral Res. 2013 Feb 28.. Abstract
submitted by kickingbird at Mar, 10, 2013 from Antiviral Res. 2013 Feb 28. (via http://www.ncbi.nlm.nih.gov/pubmed/23458714)
Highly pathogenic (HP) H5N1 influenza viruses are evolving pathogens with the potential to cause sustained human-to-human transmission and pandemic virus spread. Specific antiviral drugs can play an important ... Tamerius JD, Shaman J, Alonso WJ, et al.. Environmental Predictors of Seasonal Influenza Epidemics across Temperate and Tropical Climates. PLoS Pathog 9(3): e1003194. doi:10.1371/journal.pp. Abstract
submitted by kickingbird at Mar, 10, 2013 from PLoS Pathog 9(3): e1003194. doi:10.1371/journal.pp (via http://www.plospathogens.org/article/info:doi/10.1371/journa)
Abstract
Human influenza infections exhibit a strong seasonal cycle in temperate regions. Recent laboratory and epidemiological evidence suggests that low specific humidity conditions facilitate the ... Amesh A. Adalja. ECMO for Severe Influenza:Description of a Large French Cohort Study. Center for Biosecurity of UPMC. Abstract
submitted by kickingbird at Mar, 9, 2013 from Center for Biosecurity of UPMC (via http://www.upmc-biosecurity.org/)
When a young otherwise healthy individual develops severe acute respiratory distress syndrome (ARDS), rescue therapies are often employed to improve oxygenation, with extra-corporeal membrane oxygenation ... M Morita, etc.,al. The Lipid Mediator Protectin D1 Inhibits Influenza Virus Replication and Improves Severe Influenza. Cell, 07 March 2013. Abstract
submitted by kickingbird at Mar, 8, 2013 from Cell, 07 March 2013 (via http://www.cell.com/retrieve/pii/S009286741300216X?cc=y)
Influenza A viruses are a major cause of mortality. Given the potential for future lethal pandemics, effective drugs are needed for the treatment of severe influenza such as that caused by H5N1 viruses. ... L Pena, etc.,al. Influenza viruses with rearranged genomes as live-attenuated vaccines. J Virol, published online Feb 28. Abstract
submitted by kickingbird at Mar, 8, 2013 from J Virol, published online Feb 28 (via http://jvi.asm.org/content/early/2013/02/20/JVI.02490-12.sho)
H5N1 and H9N2 avian influenza subtypes top the World Health Organization's list for the greatest pandemic potential. Inactivated H5N1 vaccines induce limited immune responses and, in the case of live attenuated ... Noti JD, Blachere FM, McMillen CM, Lindsley WG, Ka. High Humidity Leads to Loss of Infectious Influenza Virus from Simulated Coughs. PLoS ONE 8(2): e57485. doi:10.1371/journal.pone.00. Abstract
submitted by kickingbird at Mar, 8, 2013 from PLoS ONE 8(2): e57485. doi:10.1371/journal.pone.00 (via http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjourna)
Abstract
Background
The role of relative humidity in the aerosol transmission of influenza was examined in a simulated examination room containing coughing and breathing manikins.
Methods
Nebulized ... ME Sundaram, etc.,al. Vitamin D is not associated with serologic response to influenza vaccine in adults over 50 years old. Vaccine, published online Feb 28. Abstract
submitted by kickingbird at Mar, 8, 2013 from Vaccine, published online Feb 28 (via http://www.sciencedirect.com/science/article/pii/S0264410X13)
Abstract
Vitamin D deficiency has been implicated in risk of respiratory illness. We determined whether serum vitamin D levels are related to influenza vaccine response measured by hemagglutinin antibody ... Dobrovolny HM, Reddy MB, Kamal MA, Rayner CR, Beau. Assessing Mathematical Models of Influenza Infections Using Features of the Immune Response. PLoS ONE 8(2): e57088. doi:10.1371/journal.pone.00. Abstract
submitted by kickingbird at Mar, 8, 2013 from PLoS ONE 8(2): e57088. doi:10.1371/journal.pone.00 (via http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjourna)
The role of the host immune response in determining the severity and duration of an influenza infection is still unclear. In order to identify severity factors and more accurately predict the course of ... 7491 items, 20/Page, Page[271/375][|<<] [|<] [271] [272] [273] [274] [275] [276] [277] [278] [279] [280] [>|] [>>|] |
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