Leow BL, Syamsiah Aini S, Faizul Fikri MY, Muhamma. Molecular characterisation of hemagglutinin and neuraminidase genes of the first highly pathogenic Avian Influenza H5N1 2.3.2.1c virus isolated from Sabah, Malaysia. Trop Biomed. 2022 Jun 1;39(2):160-169. Abstract
submitted by kickingbird at Jul, 16, 2022 from Trop Biomed. 2022 Jun 1;39(2):160-169 (via https://msptm.org/files/Vol39No2/tb-39-2-001-Leow-B-L.pdf)
Highly Pathogenic Avian Influenza (HPAI) is a highly contagious disease in poultry. The outbreaks can lead to flock mortality up to 100% in two to three days. In July 2018, high mortality in a commercial ... J?rgensen RL, Lerche CJ, Pedersen MS, Kirkby N, Bo. Emergence of circulating influenza A H3N2 viruses with genetic drift in the matrix gene: Be alert of false negative test results. APMIS. 2022 Jul 14. Abstract
submitted by kickingbird at Jul, 16, 2022 from APMIS. 2022 Jul 14 (via https://onlinelibrary.wiley.com/doi/10.1111/apm.13262)
In March 2022, we observed samples with a negative fluorescent signal (60.5%, n=43) for the influenza A matrix gene, and a stronger positive signal for subtype A(H3N2). Forty-three samples were positive ... Gao J, Li X, Klenow L, Malik T, Wan H, Ye Z, Danie. Antigenic comparison of the neuraminidases from recent influenza A vaccine viruses and 2019-2020 circulating strains. NPJ Vaccines. 2022 Jul 14;7(1):79. Abstract
submitted by kickingbird at Jul, 16, 2022 from NPJ Vaccines. 2022 Jul 14;7(1):79 (via https://www.nature.com/articles/s41541-022-00500-1)
Although viral-based influenza vaccines contain neuraminidase (NA or N) antigens from the recommended seasonal strains, NA is not extensively evaluated like hemagglutinin (H) during the strain selection ... Inaida S, Matsuno S, Okumura J. Longitudinal surveillance of influenza in Japan, 2006-2016. Sci Rep. 2022 Jul 14;12(1):12026. Abstract
submitted by kickingbird at Jul, 16, 2022 from Sci Rep. 2022 Jul 14;12(1):12026 (via https://www.nature.com/articles/s41598-022-15867-3)
We analysed 2006-2016 national influenza surveillance data in Japan with regards to age-, sex-, and predominant virus-related epidemic patterns and the prevalence of serum influenza virus antibodies. We ... ones JC, Zagribelnyy B, Pascua PNQ, Bezrukov DS, B. Influenza A virus polymerase acidic protein E23G/K substitutions weaken key baloxavir drug-binding contacts with minimal impact on replication and transmission. PLoS Pathog. 2022 Jul 13;18(7):e1010698. Abstract
submitted by kickingbird at Jul, 14, 2022 from PLoS Pathog. 2022 Jul 13;18(7):e1010698 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Baloxavir marboxil (BXM) is approved for treating uncomplicated influenza. The active metabolite baloxavir acid (BXA) inhibits cap-dependent endonuclease activity of the influenza virus polymerase acidic ... Caliendo V, Lewis NS, Pohlmann A, Baillie SR, Bany. Transatlantic spread of highly pathogenic avian influenza H5N1 by wild birds from Europe to North America in 2021. Sci Rep. 2022 Jul 11;12(1):11729. Abstract
submitted by kickingbird at Jul, 14, 2022 from Sci Rep. 2022 Jul 11;12(1):11729 (via https://www.nature.com/articles/s41598-022-13447-z)
Highly pathogenic avian influenza (HPAI) viruses of the A/Goose/Guangdong/1/1996 lineage (GsGd), which threaten the health of poultry, wildlife and humans, are spreading across Asia, Europe, Africa and ... Chiem K, Nogales A, Martinez-Sobrido L. Generation, Characterization, and Applications of Influenza A Reporter Viruses. Methods Mol Biol. 2022;2524:249-268. Abstract
submitted by kickingbird at Jul, 14, 2022 from Methods Mol Biol. 2022;2524:249-268 (via https://link.springer.com/protocol/10.1007/978-1-0716-2453-1)
Secondary experimental procedures such as immunostaining have been utilized to study wild-type influenza A viruses (IAV) but are inadequate to rapidly determine the virus in infected cells or for the high-throughput ... Chen J, Xu L, Liu T, Xie S, Li K, Li X, Zhang M, W. Novel Reassortant Avian Influenza A(H5N6) Virus, China, 2021. Emerg Infect Dis. 2022 Jul 12;28(8). Abstract
submitted by kickingbird at Jul, 13, 2022 from Emerg Infect Dis. 2022 Jul 12;28(8) (via https://wwwnc.cdc.gov/eid/article/28/8/21-2241_article)
Although reports of human infection with influenza A(H5N6) increased in 2021, reports of similar H5N6 virus infection in poultry are few. We detected 10 avian influenza A(H5N6) clade 2.3.4.4b viruses in ... Xu H, Palpant T, Weinberger C, Shaw DE. Characterizing Receptor Flexibility to Predict Mutations That Lead to Human Adaptation of Influenza Hemagglutinin. J Chem Theory Comput. 2022 Jul 11. Abstract
submitted by kickingbird at Jul, 13, 2022 from J Chem Theory Comput. 2022 Jul 11 (via https://pubs.acs.org/doi/10.1021/acs.jctc.1c01044)
A key step in the emergence of human pandemic influenza strains has been a switch in binding preference of the viral glycoprotein hemagglutinin (HA) from avian to human sialic acid (SA) receptors. The ... Song H, Liu X, Gao X, Li J, Shang Y, Gao W, Li Y,. Transcriptome analysis of pre-immune state induced by interferon gamma inhibiting the replication of H9N2 avian influenza viruses in chicken embryo fibroblasts. Infect Genet Evol. 2022 Jul 7:105332. Abstract
submitted by kickingbird at Jul, 13, 2022 from Infect Genet Evol. 2022 Jul 7:105332 (via https://www.sciencedirect.com/science/article/pii/S156713482)
Interferon (IFN), a critical antiviral cytokine produced by pathogens-induced cells, plays an important role in host innate immune system. In this study, to investigate the inhibition effect of IFN on ... Song Y, Zhu W, Wang Y, Deng L, Ma Y, Dong C, Gonza. Layered protein nanoparticles containing influenza B HA stalk induced sustained cross-protection against viruses spanning both viral lineages. Biomaterials. 2022 Jul 4;287:121664. Abstract
submitted by kickingbird at Jul, 13, 2022 from Biomaterials. 2022 Jul 4;287:121664 (via https://www.sciencedirect.com/science/article/abs/pii/S01429)
The influenza epidemics pose a significant threat to public health. Of them, type B influenza coincided with several severe flu outbreaks. The efficacy of the current seasonal flu vaccine is limited due ... Xu W, Wang Y, Li L, Qu X, Liu Q, Li T, Wu S, Liao. Transmembrane domain of IFITM3 is responsible for its interaction with influenza virus HA 2 subunit. Xu W, Wang Y, Li L, Qu X, Liu Q, Li T, Wu S, Liao. Abstract
submitted by kickingbird at Jul, 11, 2022 from Xu W, Wang Y, Li L, Qu X, Liu Q, Li T, Wu S, Liao (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Interferon-inducible transmembrane protein 3 (IFITM3) inhibits influenza virus infection by blocking viral membrane fusion, but the exact mechanism remains elusive. Here, we investigated the function and ... Baek YG, Lee YN, Park YR, Chung DH, Kwon JH, Si YJ. Evolution, Transmission, and Pathogenicity of High Pathogenicity Avian Influenza Virus A (H5N8) Clade 2.3.4.4, South Korea, 2014-2016. Front Vet Sci. 2022 Jun 21;9:906944. Abstract
submitted by kickingbird at Jul, 9, 2022 from Front Vet Sci. 2022 Jun 21;9:906944 (via https://www.frontiersin.org/articles/10.3389/fvets.2022.9069)
During 2014-2016, clade 2.3.4.4 H5N8 high pathogenicity avian influenza virus (HPAIV) caused the largest known avian influenza epidemic in South Korea. Based on data from earlier H5N8 outbreaks, primitive ... Tanikawa T, Fujii K, Sugie Y, Tsunekuni R, Nakayam. Comparative susceptibility of mallard (Anas platyrhynchos) to infection with high pathogenicity avian influenza virus strains (Gs/Gd lineage) isolated in Japan in 2004-2017. Vet Microbiol. 2022 Jun 28;272:109496. Abstract
submitted by kickingbird at Jul, 9, 2022 from Vet Microbiol. 2022 Jun 28;272:109496 (via https://www.sciencedirect.com/science/article/pii/S037811352)
The Goose/Guangdong-lineage (Gs/Gd) H5 high pathogenicity avian influenza viruses (HPAIVs) spread among poultry and wild birds worldwide; an association has been identified between the migration of wild ... Si L, Shen Q, Li J, Chen L, Shen J, Xiao X, Bai H,. Generation of a live attenuated influenza A vaccine by proteolysis targeting. Nat Biotechnol. 2022 Jul 4. Abstract
submitted by kickingbird at Jul, 7, 2022 from Nat Biotechnol. 2022 Jul 4 (via https://www.nature.com/articles/s41587-022-01381-4)
The usefulness of live attenuated virus vaccines has been limited by suboptimal immunogenicity, safety concerns or cumbersome manufacturing processes and techniques. Here we describe the generation of ... Kakuya F, Okubo H, Fujiyasu H, Kurisawa MJ, Kinebu. Clinical effectiveness of baloxavir marboxil against influenza in three seasons. Pediatr Int. 2022 Jan;64(1):e15169.. Abstract
submitted by kickingbird at Jul, 7, 2022 from Pediatr Int. 2022 Jan;64(1):e15169. (via https://onlinelibrary.wiley.com/doi/10.1111/ped.15169)
Background: Previous reports have not clarified the difference in clinical efficacy between baloxavir and oseltamivir against influenza.Methods: A prospective observational study was performed during 2017-2018, ... Jamoussi A, Ayed S, Merhabene T, Doghri H, Ben Khe. Severe influenza A in a Tunisian ICU sentinel SARI centre: Epidemiological and clinical features. PLoS One. 2022 Jul 6;17(7):e0270814.. Abstract
submitted by kickingbird at Jul, 7, 2022 from PLoS One. 2022 Jul 6;17(7):e0270814. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Introduction: Influenza A virus infection is a contagious acute respiratory infection which mostly evolves in an epidemic form, less frequently as pandemic outbreaks. It can take a severe clinical form ... Wang C, Qu R, Zong Y, Qin C, Liu L, Gao X, Sun H,. Enhanced stability of M1 protein mediated by a phospho-resistant mutation promotes the replication of prevailing avian influenza virus in mammals. PLoS Pathog. 2022 Jul 6;18(7):e1010645.. Abstract
submitted by kickingbird at Jul, 7, 2022 from PLoS Pathog. 2022 Jul 6;18(7):e1010645. (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Avian influenza virus (AIV) can evolve multiple strategies to combat host antiviral defenses and establish efficient infectivity in mammals, including humans. H9N2 AIV and its reassortants (such as H5N6 ... Ding L, Chen Y, Su N, Xu X, Yin J, Qiu J, Wang J,. Comparison of acute respiratory distress syndrome in patients with COVID-19 and influenza A (H7N9) virus infection. Int J Infect Dis. 2022 Jul 3:S1201-9712(22)00387-3. Abstract
submitted by kickingbird at Jul, 7, 2022 from Int J Infect Dis. 2022 Jul 3:S1201-9712(22)00387-3 (via https://www.ijidonline.com/article/S1201-9712(22)00387-3/ful)
Objectives: We aimed to compared the clinical features of acute respiratory distress syndrome (ARDS) induced by COVID-19 and H7N9 virus infections.Methods: Clinical data of 100 COVID-19 patients and 46 ... Rattanaburi S, Sawaswong V, Nimsamer P, Mayuramart. Genome characterization and mutation analysis of human influenza A virus in Thailand. Genomics Inform. 2022 Jun;20(2):e21. Abstract
submitted by kickingbird at Jul, 7, 2022 from Genomics Inform. 2022 Jun;20(2):e21 (via https://genominfo.org/journal/view.php?doi=10.5808/gi.21077)
The influenza A viruses have high mutation rates and cause a serious health problem worldwide. Therefore, this study focused on genome characterization of the viruses isolated from Thai patients based ... 8131 items, 20/Page, Page[86/407][|<<] [|<] [81] [82] [83] [84] [85] [86] [87] [88] [89] [90] [>|] [>>|] |
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