Liu X, Hong H, Wang J, Huang J, Li J, Tao Y, Liu M. Mucosal immune responses and protective efficacy elicited by oral administration AMP-ZnONPs-adjuvanted inactivated H9N2 virus in chickens. Poult Sci. 2024 Jan 26;103(4):103496. Abstract submitted by kickingbird at Feb, 9, 2024 from Poult Sci. 2024 Jan 26;103(4):103496 (via https://www.sciencedirect.com/science/article/pii/S003257912) The avian influenza virus is infected through the mucosal route, thus mucosal barrier defense is very important. While the inactivated H9N2 vaccine cannot achieve sufficient mucosal immunity, adjuvants ... Li ZA, Bajpai AK, Wang R, Liu Y, Webby RJ, Wilk E,. Systems Genetics of Influenza A Virus-infected Mice Identifies TRIM21 as a Critical Regulator of Pulmonary Innate Immune Response. Virus Res. 2024 Feb 6:199335. Abstract submitted by kickingbird at Feb, 9, 2024 from Virus Res. 2024 Feb 6:199335 (via https://pubmed.ncbi.nlm.nih.gov/38331257/) Tripartite motif 21 (TRIM21) is a cytosolic Fc receptor that targets antibody-bound, internalized pathogens for destruction. Apart from this intrinsic defense role, TRIM21 is implicated in autoimmune diseases, ... Krischuns T, Arragain B, Isel C, Paisant S, Budt M. The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun. 2024 Feb 5;15(1):1064. Abstract submitted by kickingbird at Feb, 8, 2024 from Nat Commun. 2024 Feb 5;15(1):1064 (via https://www.nature.com/articles/s41467-024-45205-2) The current model is that the influenza virus polymerase (FluPol) binds either to host RNA polymerase II (RNAP II) or to the acidic nuclear phosphoprotein 32 (ANP32), which drives its conformation and ... Yang Q, Wang B, Lemey P, Dong L, Mu T, Wiebe RA, G. Synchrony of Bird Migration with Global Dispersal of Avian Influenza Reveals Exposed Bird Orders. Nat Commun. 2024 Feb 6;15(1):1126. Abstract submitted by kickingbird at Feb, 8, 2024 from Nat Commun. 2024 Feb 6;15(1):1126 (via https://www.nature.com/articles/s41467-024-45462-1) Highly pathogenic avian influenza virus (HPAIV) A H5, particularly clade 2.3.4.4, has caused worldwide outbreaks in domestic poultry, occasional spillover to humans, and increasing deaths of diverse species ... Zhang L, Li Y, Ma N, Zhao Y, Zhao Y. Heterogeneity of influenza infection at precise scale in Yinchuan, Northwest China, 2012-2022: evidence from Joinpoint regression and spatiotemporal analysis. Sci Rep. 2024 Feb 6;14(1):3079. Abstract submitted by kickingbird at Feb, 8, 2024 from Sci Rep. 2024 Feb 6;14(1):3079 (via https://www.nature.com/articles/s41598-024-53767-w) Identifying high-risk regions and turning points of influenza with a precise spatiotemporal scale may provide effective prevention strategies. In this study, epidemiological characteristics and spatiotemporal ... Li X, Li Y, Shang X, Kong H. A sequence-based machine learning model for predicting antigenic distance for H3N2 influenza virus. Front Microbiol. 2024 Jan 19;15:1345794. Abstract submitted by kickingbird at Feb, 7, 2024 from Front Microbiol. 2024 Jan 19;15:1345794 (via https://www.frontiersin.org/journals/microbiology/articles/1) Introduction: Seasonal influenza A H3N2 viruses are constantly changing, reducing the effectiveness of existing vaccines. As a result, the World Health Organization (WHO) needs to frequently update the ... Olawuyi K, Orole O, Meseko C, Monne I, Shittu I, B. Detection of clade 2.3.4.4 highly pathogenic avian influenza H5 viruses in healthy wild birds in the Hadeji-Nguru wetland, Nigeria 2022. Influenza Other Respir Viruses. 2024 Feb 3;18(2):e. Abstract submitted by kickingbird at Feb, 7, 2024 from Influenza Other Respir Viruses. 2024 Feb 3;18(2):e (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13254) Background: The introduction of multiple avian influenza virus (AIV) subtypes into Nigeria has resulted in several poultry outbreaks purportedly linked to trade and wild birds. The role of wild birds in ... Liu K, Qi X, Bao C, Wang X, Liu X. Novel H10N3 avian influenza viruses: a potential threat to public health. Lancet Microbe. 2024 Jan 31:S2666-5247(23)00409-3. Abstract submitted by kickingbird at Feb, 4, 2024 from Lancet Microbe. 2024 Jan 31:S2666-5247(23)00409-3 (via https://www.thelancet.com/journals/lanmic/article/PIIS2666-5) Novel H10N3 avian influenza viruses have been frequently isolated from poultry across various regions of China (including Jiangsu, Zhejiang, Fujian, and other provinces) in recent years and have caused ... Gu G, Liu C, Lee SH, Chun Choi LS, Wilson MT, Pfei. Detection of a reassortant swine H1N2 influenza A virus from pigs in Hong Kong. Virol Sin. 2024 Feb 1:S1995-820X(24)00009-9. Abstract submitted by kickingbird at Feb, 4, 2024 from Virol Sin. 2024 Feb 1:S1995-820X(24)00009-9 (via https://www.sciencedirect.com/science/article/pii/S1995820X2) Influenza A viruses (IAVs) are responsible for significant respiratory illnesses in humans and a broad range of animal species. Repeated outbreaks and the rapid spread of genetically and antigenically ... Kenmoe S, Takuissu GR, Ebogo-Belobo JT, Kengne-Ndé. A systematic review of influenza virus in water environments across human, poultry, and wild bird habitats. Water Res X. 2023 Dec 13;22:100210. Abstract submitted by kickingbird at Feb, 3, 2024 from Water Res X. 2023 Dec 13;22:100210 (via https://www.sciencedirect.com/science/article/pii/S258991472) Influenza, a highly contagious acute respiratory disease, remains a major global health concern. This study aimed to comprehensively assess the prevalence of influenza virus in different aquatic environments. ... Chao S, Wang Y, Wu B, Li R, Dong J, Ji L, Li X, Li. Characterization of viral infections in children with influenza-like-illness during December 2018-January 2019. Front Cell Infect Microbiol. 2024 Jan 18;13:135181. Abstract submitted by kickingbird at Feb, 3, 2024 from Front Cell Infect Microbiol. 2024 Jan 18;13:135181 (via https://www.frontiersin.org/articles/10.3389/fcimb.2023.1351) Introduction: Respiratory viral infection (RVI) is of very concern after the outbreak of COVID-19, especially in pediatric departments. Learning pathogen spectrum of RVI in children previous the epidemic ... Li H, Sun H, Tao M, Han Q, Yu H, Li J, Lu X, Tong. Recombinant parainfluenza virus 5 expressing clade 2.3.4.4b H5 hemagglutinin protein confers broad protection against H5Ny influenza viruses. J Virol. 2024 Feb 2:e0112923. Abstract submitted by kickingbird at Feb, 3, 2024 from J Virol. 2024 Feb 2:e0112923 (via https://journals.asm.org/doi/10.1128/jvi.01129-23) The global circulation of clade 2.3.4.4b H5Ny highly pathogenic avian influenza viruses (HPAIVs) in poultry and wild birds, increasing mammal infections, continues to pose a public health threat and may ... Bessière P, Gaide N, Croville G, Crispo M, Fusade-. High pathogenicity avian influenza A (H5N1) clade 2.3.4.4b virus infection in a captive Tibetan black bear ( Ursus thibetanus): investigations based on paraffin-embedded tissues, France, 2022. Microbiol Spectr. 2024 Feb 2:e0373623. Abstract submitted by kickingbird at Feb, 3, 2024 from Microbiol Spectr. 2024 Feb 2:e0373623 (via https://journals.asm.org/doi/10.1128/spectrum.03736-23) High pathogenicity avian influenza viruses (HPAIVs) H5Nx of clade 2.3.4.4b have been circulating increasingly in both wild and domestic birds in recent years. In turn, this has led to an increase in the ... Curran SJ, Griffin EF, Ferreri LM, Kyriakis CS, Ho. Swine influenza A virus isolates containing the pandemic H1N1 origin matrix gene elicit greater disease in the murine model. Microbiol Spectr. 2024 Feb 1:e0338623. Abstract submitted by kickingbird at Feb, 3, 2024 from Microbiol Spectr. 2024 Feb 1:e0338623 (via https://journals.asm.org/doi/10.1128/spectrum.03386-23) Since the 1990s, endemic North American swine influenza A viruses (swFLUAVs) contained an internal gene segment constellation, the triple reassortment internal gene (TRIG) cassette. In 2009, the H1N1 pandemic ... Rowe T, Davis W, Wentworth DE, Ross T. Differential interferon responses to influenza A and B viruses in primary ferret respiratory epithelial cells. J Virol. 2024 Jan 31:e0149423. Abstract submitted by kickingbird at Feb, 1, 2024 from J Virol. 2024 Jan 31:e0149423 (via https://journals.asm.org/doi/10.1128/jvi.01494-23) Influenza B viruses (IBV) cocirculate with influenza A viruses (IAV) and cause periodic epidemics of disease, yet antibody and cellular responses following IBV infection are less well understood. Using ... Na L, Sun L, Yu M, Zhang Y, Zhang Y, Zhang Z, Zhan. Avian ANP32A incorporated in avian influenza A virions promotes interspecies transmission by priming early viral replication in mammals. Sci Adv. 2024 Feb 2;10(5):eadj4163. Abstract submitted by kickingbird at Feb, 1, 2024 from Sci Adv. 2024 Feb 2;10(5):eadj4163 (via https://www.science.org/doi/10.1126/sciadv.adj4163) Species-specific differences in acidic nuclear phosphoprotein 32 family member A (ANP32A) determine the restriction of avian-signature polymerase in mammalian cells. Mutations that evade this restriction, ... de Araújo AC, Silva LMN, Cho AY, Repenning M, Amga. Incursion of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus, Brazil, 2023. Emerg Infect Dis. 2024 Jan 30;30(3). Abstract submitted by kickingbird at Feb, 1, 2024 from Emerg Infect Dis. 2024 Jan 30;30(3) (via https://wwwnc.cdc.gov/eid/article/30/3/23-1157_article) We report 4 highly pathogenic avian influenza A(H5N1) clade 2.3.4.4.b viruses in samples collected during June 2023 from Royal terns and Cabot's terns in Brazil. Phylodynamic analysis revealed viral movement ... Fang K, Song W, Zhang Y, Zheng Y, You C, Hu J, Liu. Comparative analysis and prediction of avian influenza in Shangrao city, China from 2016 to 2022. Virology. 2024 Jan 24;592:109995. Abstract submitted by kickingbird at Feb, 1, 2024 from Virology. 2024 Jan 24;592:109995 (via https://www.sciencedirect.com/science/article/abs/pii/S00426) The aim of this study was to investigate the effects of vaccination, COVID-19 pandemic and migration of migratory birds on the avian influenza positivity rate in Shangrao City and to predict the future ... Jia Y, Yang J, Wang Z, Du Y, Cui J, Wang L, Guo F,. Genetic properties and pathogenicity of a novel reassortant H10N5 influenza virus from wild birds. Arch Virol. 2017 May;162(5):1349-1353. Abstract submitted by kickingbird at Jan, 31, 2024 from Arch Virol. 2017 May;162(5):1349-1353 (via https://link.springer.com/article/10.1007/s00705-017-3234-3) In this study, we analyzed the genome of a H10N5 influenza virus from wild birds. This virus was identified as a novel reassortant virus with internal genes from multiple subtypes and of distinct origins. ... Wang N, Zou W, Yang Y, Guo X, Hua Y, Zhang Q, Zhao. Complete genome sequence of an H10N5 avian influenza virus isolated from pigs in central China. J Virol. 2012 Dec;86(24):13865-6. Abstract submitted by kickingbird at Jan, 31, 2024 from J Virol. 2012 Dec;86(24):13865-6 (via https://journals.asm.org/doi/10.1128/jvi.02687-12) An avian H10N5 influenza virus, A/swine/Hubei/10/2008/H10N5, was isolated from pigs in the Hubei Province of central China. 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