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Credille CV, et al. Structure-Activity Relationships in Metal-Binding Pharmacophores for Influenza Endonuclease. J Med Chem. 2018 Oct 16.  Abstract  
submitted by kickingbird at Oct, 24, 2018 from J Med Chem. 2018 Oct 16 (via https://www.ncbi.nlm.nih.gov/pubmed/30351002)
Metalloenzymes represent an important target space for drug discovery. A limitation to the early development of metalloenzyme inhibitors has been the lack of established structure-activity relationships ...

Gong YN, Kuo RL, Chen GW, Shih SR. Centennial review of influenza in Taiwan. Biomed J. 2018 Aug;41(4):234-241..  Abstract  
submitted by kickingbird at Oct, 24, 2018 from Biomed J. 2018 Aug;41(4):234-241. (via https://www.ncbi.nlm.nih.gov/pubmed/30348266)
The history of influenza in Taiwan can be traced up to the 1918 H1N1 Spanish flu pandemic, followed by several others including the 1957 H2N2, 1968 H3N2, and the 2009 new H1N1. A couple of avian influenza ...

Delgadillo-Gutiérrez K, et al. Stability of retroviral pseudotypes carrying the hemagglutinin of avian influenza viruses under various storage conditions. J Virol Methods. 2018 Oct 19..  Abstract  
submitted by kickingbird at Oct, 23, 2018 from J Virol Methods. 2018 Oct 19. (via https://www.ncbi.nlm.nih.gov/pubmed/30347199)
Retroviral pseudotypes are broadly used as safe instruments to mimic the structure and surface of highly pathogenic viruses. They have been employed for the discovery of new drugs, as diagnostic tools ...

Davis RL, et al. The culture of primary duck endothelial cells for the study of avian influenza. BMC Microbiol. 2018 Oct 19;18(1):138.  Abstract  
submitted by kickingbird at Oct, 22, 2018 from BMC Microbiol. 2018 Oct 19;18(1):138 (via https://www.ncbi.nlm.nih.gov/pubmed/30340527)
BACKGROUND: Endothelial cells play a major role in highly pathogenic avian influenza (HPAI) virus pathogenesis in gallinaceous poultry species (e.g. chicken, turkey and quail). Upon infection of gallinaceous ...

Ye S, Cowled CJ, Yap CH, Stambas J. Deep sequencing of primary human lung epithelial cells challenged with H5N1 influenza virus reveals a proviral role for CEACAM1. Sci Rep. 2018 Oct 19;8(1):15468..  Abstract  
submitted by kickingbird at Oct, 21, 2018 from Sci Rep. 2018 Oct 19;8(1):15468. (via https://www.ncbi.nlm.nih.gov/pubmed/30341336)
Current prophylactic and therapeutic strategies targeting human influenza viruses include vaccines and antivirals. Given variable rates of vaccine efficacy and antiviral resistance, alternative strategies ...

Pillsbury AJ, et al. Active surveillance of 2017 seasonal influenza vaccine safety: an observational cohort study of individuals aged 6 months and older in Australia. BMJ Open. 2018 Oct 18;8(10):e023263..  Abstract  
submitted by kickingbird at Oct, 21, 2018 from BMJ Open. 2018 Oct 18;8(10):e023263. (via https://www.ncbi.nlm.nih.gov/pubmed/30341132)
OBJECTIVE: To actively solicit adverse events experienced in the days following immunisation with quadrivalent inactivated influenza vaccine using Australia's near real-time, participant-based vaccine ...

Bartsch SM, et al. Epidemiologic and economic impact of pharmacies as vaccination locations during an influenza epidemic. Vaccine. 2018 Oct 5..  Abstract  
submitted by kickingbird at Oct, 21, 2018 from Vaccine. 2018 Oct 5. (via https://www.ncbi.nlm.nih.gov/pubmed/30340884)
INTRODUCTION: During an influenza epidemic, where early vaccination is crucial, pharmacies may be a resource to increase vaccine distribution reach and capacity.METHODS: We utilized an agent-based model ...

St Charles KM, et al. Avian Influenza in the U.S. Commercial Upland Game Bird Industry: An Analysis of Selected Practices as Potential Exposure Pathways and Surveillance System Data Reporting. Avian Dis. 2018 Sep;62(3):307-315..  Abstract  
submitted by kickingbird at Oct, 21, 2018 from Avian Dis. 2018 Sep;62(3):307-315. (via https://www.ncbi.nlm.nih.gov/pubmed/30339513)
Producing a smaller yield of higher-value birds compared to conventional poultry production, the U.S. commercial upland game bird industry deals primarily in the sale of live birds for recreational hunting. ...

Ge Y, et al. Detection of reassortant avian influenza A (H11N9) virus in wild birds in China. Transbound Emerg Dis. 2018 Oct 19.  Abstract  
submitted by kickingbird at Oct, 21, 2018 from Transbound Emerg Dis. 2018 Oct 19 (via https://www.ncbi.nlm.nih.gov/pubmed/30338936)
Human infectious avian influenza virus (AIV) H7N9 emerged in China in 2013. The N9 gene of H7N9, which has the ability to cause death in humans, originated from an H11N9 influenza strain circulating in ...

Chen P, Chen E, Chen L, Zhou XJ, Liu R. Detecting early-warning signals of influenza outbreak based on dynamic network marker. J Cell Mol Med. 2018 Oct 19..  Abstract  
submitted by kickingbird at Oct, 21, 2018 from J Cell Mol Med. 2018 Oct 19. (via https://www.ncbi.nlm.nih.gov/pubmed/30338927)
The seasonal outbreaks of influenza infection cause globally respiratory illness, or even death in all age groups. Given early-warning signals preceding the influenza outbreak, timely intervention such ...

Sun Y, et al. Aflatoxin B1 Promotes Influenza Replication and Increases Virus Related Lung Damage via Activation of TLR4 Signaling. Front Immunol. 2018 Oct 4;9:2297.  Abstract  
submitted by kickingbird at Oct, 21, 2018 from Front Immunol. 2018 Oct 4;9:2297 (via https://www.ncbi.nlm.nih.gov/pubmed/30337931)
Aflatoxin B1 (AFB1), which alters immune responses to mammals, is one of the most common mycotoxins in feeds and food. Swine influenza virus (SIV) is a major pathogen of both animals and humans. However, ...

Hughes HR, Brockmeier SL, Loving CL. Bordetella bronchiseptica Colonization Limits Efficacy, but Not Immunogenicity, of Live-Attenuated Influenza Virus Vaccine and Enhances Pathogenesis After Influenza Challenge. Front Immunol. 2018 Oct 4;9:2255.  Abstract  
submitted by kickingbird at Oct, 21, 2018 from Front Immunol. 2018 Oct 4;9:2255 (via https://www.ncbi.nlm.nih.gov/pubmed/30337924)
Intranasally administered live-attenuated influenza virus (LAIV) vaccines provide significant protection against heterologous influenza A virus (IAV) challenge. However, LAIV administration can modify ...

Gopal R, et al. STAT2 Signaling Regulates Macrophage Phenotype During Influenza and Bacterial Super-Infection. Front Immunol. 2018 Sep 25;9:2151.  Abstract  
submitted by kickingbird at Oct, 21, 2018 from Front Immunol. 2018 Sep 25;9:2151 (via https://www.ncbi.nlm.nih.gov/pubmed/30337919)
Influenza is a common respiratory virus that infects between 5 and 20% of the US population and results in 30,000 deaths annually. A primary cause of influenza-associated death is secondary bacterial pneumonia. ...

Lisovski S, et al. The roles of migratory and resident birds in local avian influenza infection dynamics. J Appl Ecol. 2018 Nov;55(6):2963-2975..  Abstract  
submitted by kickingbird at Oct, 21, 2018 from J Appl Ecol. 2018 Nov;55(6):2963-2975. (via https://www.ncbi.nlm.nih.gov/pubmed/30337766)
Migratory birds are an increasing focus of interest when it comes to infection dynamics and the spread of avian influenza viruses (AIV). However, we lack detailed understanding migratory birds' contribution ...

Mohebbi A, et al. Molecular Epidemiology of the Hemagglutinin gene of prevalent influenza virus A/H1N1/pdm09 among patient in Iran. Virus Res. 2018 Oct 15.  Abstract  
submitted by kickingbird at Oct, 21, 2018 from Virus Res. 2018 Oct 15 (via https://www.ncbi.nlm.nih.gov/pubmed/30336188)
In 2015, the influenza virus A/H1N1/pdm09 strain outbreak became prevalent throughout the different provinces of Iran. There are relatively limited complete genetic sequences available for this virus from ...

Ali ST, Cowling BJ, Lau EHY, Fang VJ, Leung GM.. Mitigation of Influenza B Epidemic with School Closures, Hong Kong, 2018. Emerg Infect Dis. 2018 Nov;24(11):2071-2073.  Abstract  
submitted by kickingbird at Oct, 21, 2018 from Emerg Infect Dis. 2018 Nov;24(11):2071-2073 (via https://www.ncbi.nlm.nih.gov/pubmed/30334723)
In winter 2018, schools in Hong Kong were closed 1 week before the scheduled Chinese New Year holiday to mitigate an influenza B virus epidemic. The intervention occurred after the epidemic peak and reduced ...

Zhang Y, et al. Hospitalizations for Influenza-Associated Severe Acute Respiratory Infection, Beijing, China, 2014~2016. Emerg Infect Dis. 2018 Nov;24(11):2098-2102.  Abstract  
submitted by kickingbird at Oct, 21, 2018 from Emerg Infect Dis. 2018 Nov;24(11):2098-2102 (via https://wwwnc.cdc.gov/eid/article/24/11/17-1410_article)
We analyzed surveillance data for 2 sentinel hospitals to estimate the influenza-associated severe acute respiratory infection hospitalization rate in Beijing, China. The rate was 39 and 37 per 100,000 ...

Kumar P, Gaur P, Kumari R, Lal SK. Influenza A virus neuraminidase protein interacts with Hsp90, to stabilize itself and enhance cell survival. J Cell Biochem. 2018 Oct 18..  Abstract  
submitted by kickingbird at Oct, 21, 2018 from J Cell Biochem. 2018 Oct 18. (via https://www.ncbi.nlm.nih.gov/pubmed/30335904)
Neuraminidase protein (NA) of influenza A virus (IAV) is popularly known for its sialidase function to assist in the release of progeny virus. However, involvement of NA in other stages of the IAV life ...

Zheng Y, et al. Canine Influenza Virus is Mildly Restricted by Canine Tetherin Protein. Viruses. 2018 Oct 16;10(10).  Abstract  
submitted by kickingbird at Oct, 21, 2018 from Viruses. 2018 Oct 16;10(10) (via https://www.ncbi.nlm.nih.gov/pubmed/30332780)
Tetherin (BST2/CD317/HM1.24) has emerged as a key host-cell ·defence molecule that acts by inhibiting the release and spread of diverse enveloped virions from infected cells. We analysed the biological ...

Im SP, et al. Potential Use of Genetically Engineered Variable Lymphocyte Receptor B Specific to Avian Influenza Virus H9N2. J Immunol. 2018 Oct 17.  Abstract  
submitted by kickingbird at Oct, 21, 2018 from J Immunol. 2018 Oct 17 (via https://www.ncbi.nlm.nih.gov/pubmed/30333123)
The variable lymphocyte receptor (VLR) B of jawless vertebrates functions as a secreted Ab of jawed vertebrates and has emerged as an alternative Ab with a single polypeptide chain. After observing an ...

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