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2024-11-26 5:30:43
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Sakuma S, Uchida Y, Kajita M, Tanikawa T, Mine J,. First Outbreak of an H5N8 Highly Pathogenic Avian Influenza Virus on a Chicken Farm in Japan in 2020. Viruses. 2021 Mar 16;13(3):489.  Abstract  
submitted by kickingbird at Apr, 4, 2021 from Viruses. 2021 Mar 16;13(3):489 (via https://www.mdpi.com/1999-4915/13/3/489)
On 5 November 2020, a confirmed outbreak due to an H5N8 highly pathogenic avian influenza virus (HPAIV) occurred at an egg-hen farm in Kagawa prefecture (western Japan). This virus, A/chicken/Kagawa/11C/2020 ...

Baek YG, Lee YN, Lee DH, Shin JI, Lee JH, Chung DH. Multiple Reassortants of H5N8 Clade 2.3.4.4b Highly Pathogenic Avian Influenza Viruses Detected in South Korea during the Winter of 2020-2021. Viruses. 2021 Mar 16;13(3):490.  Abstract  
submitted by kickingbird at Apr, 4, 2021 from Viruses. 2021 Mar 16;13(3):490 (via https://www.mdpi.com/1999-4915/13/3/490)
During October 2020-January 2021, we isolated a total of 67 highly pathogenic avian influenza (HPAI) H5N8 viruses from wild birds and outbreaks in poultry in South Korea. We sequenced the isolates and ...

McKellar J, Rebendenne A, Wencker M, Moncorgé O, G. Mammalian and Avian Host Cell Influenza A Restriction Factors. Viruses. 2021 Mar 22;13(3):522.  Abstract  
submitted by kickingbird at Apr, 4, 2021 from Viruses. 2021 Mar 22;13(3):522 (via https://www.mdpi.com/1999-4915/13/3/522)
The threat of a new influenza pandemic is real. With past pandemics claiming millions of lives, finding new ways to combat this virus is essential. Host cells have developed a multi-modular system to detect ...

Michalak P, Piasecka J, Szutkowska B, Kierzek R, B. Conserved Structural Motifs of Two Distant IAV Subtypes in Genomic Segment 5 RNA. Viruses. 2021 Mar 22;13(3):525.  Abstract  
submitted by kickingbird at Apr, 4, 2021 from Viruses. 2021 Mar 22;13(3):525 (via https://www.mdpi.com/1999-4915/13/3/525)
The functionality of RNA is fully dependent on its structure. For the influenza A virus (IAV), there are confirmed structural motifs mediating processes which are important for the viral replication cycle, ...

Ferahkaya E. Oseltamivir-Induced Mania in a Patient With Influenza A. Clin Neuropharmacol. 2021 Mar 12.  Abstract  
submitted by kickingbird at Apr, 4, 2021 from Clin Neuropharmacol. 2021 Mar 12 (via https://journals.lww.com/clinicalneuropharm/Abstract/9000/Os)
Oseltamivir is an antiviral drug often preferred in treating viral infections. Its use has increased owing to annual influenza outbreaks and the COVID-19 pandemic. Although its adverse effects are often ...

Mengual-Chuliá B, Alonso-Cordero A, Cano L, Del Ma. Surveillance of Influenza A resistance to polymerase complex inhibitors by whole genome analysis, 2016-17, 2017-18 and 2018-19 Seasons, Eastern Spain. Antimicrob Agents Chemother. 2021 Mar 29:AAC.02718.  Abstract  
submitted by kickingbird at Mar, 31, 2021 from Antimicrob Agents Chemother. 2021 Mar 29:AAC.02718 (via https://aac.asm.org/content/early/2021/03/23/AAC.02718-20)
Molecular surveillance by whole genome sequencing was used to monitor the susceptibility of circulating Influenza A viruses to three polymerase complex inhibitors. A total of 12 resistance substitutions ...

Dilai M, Fassi Fihri O, El Harrak M, Bouchiba A, D. An Evaluation of Three Different Primary Equine Influenza Vaccination Intervals in Foals. J Equine Vet Sci. 2021 Apr;99:103397.  Abstract  
submitted by kickingbird at Mar, 31, 2021 from J Equine Vet Sci. 2021 Apr;99:103397 (via https://www.sciencedirect.com/science/article/abs/pii/S07370)
In order to evaluate the effect of three different primary vaccination intervals on EI vaccine response, 21 unvaccinated thoroughbred foals were randomly divided into three groups of 7 and vaccinated with ...

Marriott AC, Gooch KE, Brown PJ, Ryan KA, Jones NJ. Severity of heterosubtypic influenza virus infection in ferrets is reduced by live attenuated influenza vaccine. NPJ Vaccines. 2021 Mar 29;6(1):43..  Abstract  
submitted by kickingbird at Mar, 31, 2021 from NPJ Vaccines. 2021 Mar 29;6(1):43. (via https://www.nature.com/articles/s41541-021-00306-7)
Live attenuated influenza vaccine (LAIV) is widely used to protect humans from seasonal influenza infection, particularly in children. In contrast to inactivated vaccines, the LAIV can induce both mucosal ...

Tang YS, Xu S, Chen YW, Wang JH, Shaw PC. Crystal structures of influenza nucleoprotein complexed with nucleic acid provide insights into the mechanism of RNA interaction. Nucleic Acids Res. 2021 Mar 30:gkab203.  Abstract  
submitted by kickingbird at Mar, 31, 2021 from Nucleic Acids Res. 2021 Mar 30:gkab203 (via https://academic.oup.com/nar/advance-article/doi/10.1093/nar)
The nucleoprotein (NP) of influenza virus is the core component of the ribonucleoprotein (RNP) and performs multiple structural and functional roles. Structures of the influenza A, B and D NP molecules ...

MacIntyre CR, Chughtai AA, Das A, Rahman B, Moa AM. Effect of statin use on the risk of influenza and influenza vaccine effectiveness. Int J Cardiol. 2021 Mar 25:S0167-5273(21)00559-3..  Abstract  
submitted by kickingbird at Mar, 30, 2021 from Int J Cardiol. 2021 Mar 25:S0167-5273(21)00559-3. (via https://www.internationaljournalofcardiology.com/article/S01)
Background Some studies have shown that statins reduce the efficacy of influenza vaccine. The aim was to examine the impact of statins on influenza and influenza vaccine effectiveness (VE). Methods This ...

Xie XT, Yitbarek A, Astill J, Singh S, Khan SU, Sh. Within-host model of respiratory virus shedding and antibody response to H9N2 avian influenza virus vaccination and infection in chickens. Infect Dis Model. 2021 Mar 4;6:490-502.  Abstract  
submitted by kickingbird at Mar, 30, 2021 from Infect Dis Model. 2021 Mar 4;6:490-502 (via https://www.sciencedirect.com/science/article/pii/S246804272)
Avian influenza virus (AIV) H9N2 subtype is an infectious pathogen that can affect both the respiratory and gastrointestinal systems in chickens and continues to have an important economic impact on the ...

Heo GB, Kye SJ, Sagong M, Lee EK, Lee KN, Lee YN,. Genetic characterization of H9N2 avian influenza virus previously unrecognized in Korea. J Vet Sci. 2021 Mar;22(2):e21.  Abstract  
submitted by kickingbird at Mar, 29, 2021 from J Vet Sci. 2021 Mar;22(2):e21 (via https://vetsci.org/DOIx.php?id=10.4142/jvs.2021.22.e21)
In this study, we describe the isolation and characterization of previously unreported Y280-lineage H9N2 viruses from two live bird markets in Korea in June 2020. Genetic analysis revealed that they were ...

Wang X, Lin X, Zheng Z, Lu B, Wang J, Tan AH, Zhao. Host-derived lipids orchestrate pulmonary γδ T cell response to provide early protection against influenza virus infection. Nat Commun. 2021 Mar 26;12(1):1914.  Abstract  
submitted by kickingbird at Mar, 28, 2021 from Nat Commun. 2021 Mar 26;12(1):1914 (via https://www.nature.com/articles/s41467-021-22242-9)
Innate immunity is important for host defense by eliciting rapid anti-viral responses and bridging adaptive immunity. Here, we show that endogenous lipids released from virus-infected host cells activate ...

Wu M, Su R, Gu Y, Yu Y, Li S, Sun H, Pan L, Cui X,. Molecular Characteristics, Antigenicity, Pathogenicity, and Zoonotic Potential of a H3N2 Canine Influenza Virus Currently Circulating in South China. Front Microbiol. 2021 Mar 9;12:628979..  Abstract  
submitted by kickingbird at Mar, 28, 2021 from Front Microbiol. 2021 Mar 9;12:628979. (via https://www.frontiersin.org/articles/10.3389/fmicb.2021.6289)
Canine influenza viruses (CIVs) could be a source of influenza viruses which infect humans because canine are important companion pets. To assess the potential risk of H3N2 CIVs currently circulating in ...

Reis R, Adrag?o F, Parente C, Nunes I, Ramos A, Na. A Seasonal Cause of Encephalitis: Influenza Virus A (H3N1) Infection. Eur J Case Rep Intern Med. 2021 Feb 24;8(3):002336.  Abstract  
submitted by kickingbird at Mar, 28, 2021 from Eur J Case Rep Intern Med. 2021 Feb 24;8(3):002336 (via https://www.ejcrim.com/index.php/EJCRIM/article/view/2336)
Influenza virus infection can have a range of presentations, from asymptomatic to life-threatening disease. We present the case of a 57-year-old woman with a known history of schizophrenia (controlled ...

Krischuns T, Lukarska M, Naffakh N, Cusack S. Influenza Virus RNA-Dependent RNA Polymerase and the Host Transcriptional Apparatus. Annu Rev Biochem. 2021 Mar 26.  Abstract  
submitted by kickingbird at Mar, 28, 2021 from Annu Rev Biochem. 2021 Mar 26 (via https://www.annualreviews.org/doi/10.1146/annurev-biochem-07)
Influenza virus RNA-dependent RNA polymerase (FluPol) transcribes the viral RNA genome in the infected cell nucleus. In the 1970s, researchers showed that viral transcription depends on host RNA polymerase ...

Huang C, Yu J, Hause BM, Park JY, Sreenivasan C, U. Emergence of New Phylogenetic Lineage of Influenza D virus with Broad Antigenicity in California, United States. Emerg Microbes Infect. 2021 Mar 26:1-10.  Abstract  
submitted by kickingbird at Mar, 28, 2021 from Emerg Microbes Infect. 2021 Mar 26:1-10 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2021.1)
Influenza D virus (IDV), with bovines as a primary host, circulates widely in cattle populations across North America and Eurasia. Here we report the identification of a novel IDV group with broad antigenicity ...

Slaine PD, Kleer M, Duguay BA, Pringle ES, Kadijk. Thiopurines activate an antiviral unfolded protein response that blocks influenza A virus glycoprotein accumulation. J Virol. 2021 Mar 24:JVI.00453-21.  Abstract  
submitted by kickingbird at Mar, 26, 2021 from J Virol. 2021 Mar 24:JVI.00453-21 (via https://jvi.asm.org/content/early/2021/03/18/JVI.00453-21)
Influenza A viruses (IAVs) utilize host shutoff mechanisms to limit antiviral gene expression and redirect translation machinery to the synthesis of viral proteins. Previously, we showed that IAV replication ...

Boyoglu-Barnum S, Ellis D, Gillespie RA, Hutchinso. Quadrivalent influenza nanoparticle vaccines induce broad protection. Nature. 2021 Mar 24.  Abstract  
submitted by kickingbird at Mar, 26, 2021 from Nature. 2021 Mar 24 (via https://www.nature.com/articles/s41586-021-03365-x)
Influenza vaccines that confer broad and durable protection against diverse viral strains would have a major effect on global health, as they would lessen the need for annual vaccine reformulation and ...

Chen L, Zhu L, Chen J. Human Interferon Inducible Transmembrane Protein 3 (IFITM3) Inhibits Influenza Virus A Replication and Inflammation by Interacting with ABHD16A. Biomed Res Int. 2021 Mar 3;2021:6652147.  Abstract  
submitted by kickingbird at Mar, 26, 2021 from Biomed Res Int. 2021 Mar 3;2021:6652147 (via https://www.hindawi.com/journals/bmri/2021/6652147/)
Studies have shown that human interferon inducible transmembrane protein (hIFITMs) family proteins have broad-spectrum antiviral capabilities. Preliminary studies in our laboratory have tentatively proved ...

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