Yadav M, Igarashi M, Yamamoto N. Dynamic residue interaction network analysis of the oseltamivir binding site of N1 neuraminidase and its H274Y mutation site conferring drug resistance in influenza A virus. PeerJ. 2021 Jun 2;9:e11552. Abstract
submitted by kickingbird at Jun, 19, 2021 from PeerJ. 2021 Jun 2;9:e11552 (via https://peerj.com/articles/11552/)
Background: Oseltamivir (OTV)-resistant influenza virus exhibits His-to-Tyr mutation at residue 274 (H274Y) in N1 neuraminidase (NA). However, the molecular mechanisms by which the H274Y mutation in NA ... Zhang J, Li X, Wang X, Ye H, Li B, Chen Y, Chen J,. Genomic evolution, transmission dynamics, and pathogenicity of avian influenza A (H5N8) viruses emerging in China, 2020. Virus Evol. 2021 May 6;7(1):veab046. Abstract
submitted by kickingbird at Jun, 19, 2021 from Virus Evol. 2021 May 6;7(1):veab046 (via https://academic.oup.com/ve/article/7/1/veab046/6270935)
Multiple recent outbreaks of highly pathogenic H5N8 viruses originating in aquatic birds frequently occurred in most European countries, Russia, South Korea, and Japan during the winter of 2020-21, and ... Kavian N, Hachim A, Cowling BJ, Valkenburg SA. Repeated influenza vaccination provides cumulative protection from distinct H3N2 viruses. Clin Transl Immunology. 2021 Jun 13;10(6):e1297. Abstract
submitted by kickingbird at Jun, 18, 2021 from Clin Transl Immunology. 2021 Jun 13;10(6):e1297 (via https://onlinelibrary.wiley.com/doi/10.1002/cti2.1297)
Objectives: Current inactivated influenza vaccines provide suboptimal protection against antigenic drift, and repeated annual vaccinations shape antibody specificity but the effect on protection from infection ... Yu Y, Wu M, Cui X, Xu F, Wen F, Pan L, Li S, Sun H. Pathogenicity and transmissibility of current H3N2 swine influenza virus in Southern China: A zoonotic potential. Transbound Emerg Dis. 2021 Jun 15. Abstract
submitted by kickingbird at Jun, 17, 2021 from Transbound Emerg Dis. 2021 Jun 15 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14190)
Swine are considered as "mixing vessels" of influenza A viruses and play an important role in the generation of novel influenza pandemics. In this study, we described that the H3N2 swine influenza (swH3N2) ... Blumenkrantz DR, Mehoke T, Shaw-Saliba K, Powell H. Identification of H3N2 NA and PB1-F2 genetic variants and their association with disease symptoms during the 2014-15 influenza season. Virus Evol. 2021 Jun 4;7(1):veab047. Abstract
submitted by kickingbird at Jun, 17, 2021 from Virus Evol. 2021 Jun 4;7(1):veab047 (via https://academic.oup.com/ve/article/7/1/veab047/6272594)
The 2014-15 influenza season saw the emergence of an H3N2 antigenic drift variant that formed the 3C.2a HA clade. Whole viral genomes were sequenced from nasopharyngeal swabs of ninety-four patients with ... Ghabeshi S, Ebrahimie E, Yavarian J, Salimi V, Sha. Molecular characterization of low pathogenic avian influenza H9N2 virus during co-circulation with newly-emerged highly pathogenic avian influenza H5N8 virus in Iran. Acta Virol. 2021;65(2):200-211. Abstract
submitted by kickingbird at Jun, 17, 2021 from Acta Virol. 2021;65(2):200-211 (via https://pubmed.ncbi.nlm.nih.gov/34130471/)
Identification of molecular characteristics of low pathogenic avian influenza (LPAI) H9N2 virus provides insights into the evolution of this subtype due to the modulation of genomic characteristics in ... Guthmiller JJ, Utset HA, Henry C, Li L, Zheng NY,. An Egg-Derived Sulfated N-Acetyllactosamine Glycan Is an Antigenic Decoy of Influenza Virus Vaccines. mBio. 2021 Jun 15:e0083821. Abstract
submitted by kickingbird at Jun, 16, 2021 from mBio. 2021 Jun 15:e0083821 (via https://journals.asm.org/doi/10.1128/mBio.00838-21)
Influenza viruses grown in eggs for the purposes of vaccine generation often acquire mutations during egg adaptation or possess different glycosylation patterns than viruses circulating among humans. Here, ... Kwon JH, Lee DH, Criado MF, Killmaster L, Ali MZ,. Genetic evolution and transmission dynamics of clade 2.3.2.1a highly pathogenic avian influenza A/H5N1 viruses in Bangladesh. Virus Evol. 2020 Jun 13;6(2):veaa046. Abstract
submitted by kickingbird at Jun, 16, 2021 from Virus Evol. 2020 Jun 13;6(2):veaa046 (via https://academic.oup.com/ve/article/6/2/veaa046/5857140)
Asian lineage A/H5N1 highly pathogenic avian influenza viruses (HPAIVs) have been responsible for continuous outbreaks in Bangladesh since 2007. Although clades 2.2.2 and 2.3.4.2 HPAIVs have disappeared ... Zhao T, Asawa K, Masuda T, Honda A, Kushiro K, Cab. Fluorescent polymeric nanoparticle for ratiometric temperature sensing allows real-time monitoring in influenza virus-infected cells. J Colloid Interface Sci. 2021 Jun 1;601:825-832. Abstract
submitted by kickingbird at Jun, 15, 2021 from J Colloid Interface Sci. 2021 Jun 1;601:825-832 (via https://www.sciencedirect.com/science/article/abs/pii/S00219)
Temperature is a key indicator of infection and disease, however, it is difficult to measure at a cellular level. Nanoparticles are applied to measure the cellular temperature, and enhancement of the stability ... Madslien K, Moldal T, Gjerset B, Gudmundsson S, Fo. First detection of highly pathogenic avian influenza virus in Norway. BMC Vet Res. 2021 Jun 12;17(1):218. Abstract
submitted by kickingbird at Jun, 15, 2021 from BMC Vet Res. 2021 Jun 12;17(1):218 (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
Background: Several outbreaks of highly pathogenic avian influenza (HPAI) caused by influenza A virus of subtype H5N8 have been reported in wild birds and poultry in Europe during autumn 2020. Norway is ... Song W, Guo J, Ni X, Wu J, Xia W, He F, Wang X, Fa. Changes of avian influenza virus subtypes before and after vaccination in live poultry in Nanchang, China from 2016 to 2019. Microbes Infect. 2021 Jun 8:104848. Abstract
submitted by kickingbird at Jun, 15, 2021 from Microbes Infect. 2021 Jun 8:104848 (via https://www.sciencedirect.com/science/article/pii/S128645792)
We investigated fluctuations in the detection rates of avian influenza virus (AIV) subtypes H5, H7, and H9 in live bird markets (LBMs) in Nanchang city, Chinese province Jiangxi, before and after the Chinese ... Schroff P, Hovey JR, Tharumia Jagadeesan C, Nagala. Cardiac Tamponade Secondary to Influenza B Infection. Cureus. 2021 May 7;13(5):e14888. Abstract
submitted by kickingbird at Jun, 12, 2021 from Cureus. 2021 May 7;13(5):e14888 (via https://www.cureus.com/articles/58416-cardiac-tamponade-seco)
Every year, Influenza infection contributes to significant morbidity and mortality carrying a huge economic burden. Extra-pulmonary manifestations are increasingly being recognized. We present a 29-year-old ... Ferrara F, Del Rosario JMM, da Costa KAS, Kinsley. Development of Lentiviral Vectors Pseudotyped With Influenza B Hemagglutinins: Application in Vaccine Immunogenicity, mAb Potency, and Sero-Surveillance Studies. Front Immunol. 2021 May 24;12:661379. Abstract
submitted by kickingbird at Jun, 12, 2021 from Front Immunol. 2021 May 24;12:661379 (via https://www.frontiersin.org/articles/10.3389/fimmu.2021.6613)
Influenza B viruses (IBV) cause respiratory disease epidemics in humans and are therefore components of seasonal influenza vaccines. Serological methods are employed to evaluate vaccine immunogenicity ... Xing L, Chen Y, Chen B, Bu L, Liu Y, Zeng Z, Guan. Antigenic Drift of the Hemagglutinin from an Influenza A (H1N1) pdm09 Clinical Isolate Increases its Pathogenicity In Vitro. Virol Sin. 2021 Jun 9:1–8. doi: 10.1007/s12250-021. Abstract
submitted by kickingbird at Jun, 12, 2021 from Virol Sin. 2021 Jun 9:1–8. doi: 10.1007/s12250-021 (via https://link.springer.com/article/10.1007/s12250-021-00401-y)
The influenza A (H1N1) pdm09 virus emerged in 2009 and has been continuously circulating in humans for over ten years. Here, we analyzed a clinical influenza A (H1N1) pdm09-infected patient case hospitalized ... Liu S, Mok BW, Deng S, Liu H, Wang P, Song W, Chen. Mammalian cells use the autophagy process to restrict avian influenza virus replication. Cell Rep. 2021 Jun 8;35(10):109213. Abstract
submitted by kickingbird at Jun, 12, 2021 from Cell Rep. 2021 Jun 8;35(10):109213 (via https://www.cell.com/cell-reports/fulltext/S2211-1247(21)005)
Host adaptive mutations in the influenza A virus (IAV) PB2 protein are critical for human infection, but their molecular action is not well understood. We observe that when IAV containing avian PB2 infects ... Criado MF, Moresco KA, Stallknecht DE, Swayne DE. Low-pathogenicity influenza viruses replicate differently in laughing gulls and mallards. Influenza Other Respir Viruses. 2021 Jun 10. Abstract
submitted by kickingbird at Jun, 12, 2021 from Influenza Other Respir Viruses. 2021 Jun 10 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.12878)
Wild aquatic birds are natural reservoirs of low-pathogenicity avian influenza viruses (LPAIVs). Laughing gulls inoculated with four gull-origin LPAIVs (H7N3, H6N4, H3N8, and H2N3) had a predominate respiratory ... Jiang D, Tian Y, Zhang Y, Lu X, Xiao D, Zhou C. One-step fast and label-free imaging array for multiplexed detection of trace avian influenza viruses. Anal Chim Acta. 2021 Aug 1;1171:338645. Abstract
submitted by kickingbird at Jun, 12, 2021 from Anal Chim Acta. 2021 Aug 1;1171:338645 (via https://www.sciencedirect.com/science/article/abs/pii/S00032)
Rapid and low-cost diagnosis of multiple infectious diseases is of great significance especially in densely populated or resource-constrained settings. Herein, we developed a one-step fast and label-free ... Barnard KN, Wasik BR, Alford-Lawrence BK, Hayward. Sequence dynamics of three influenza A virus strains grown in different MDCK cell lines, including those expressing different sialic acid receptors. J Evol Biol. 2021 Jun 11. Abstract
submitted by kickingbird at Jun, 12, 2021 from J Evol Biol. 2021 Jun 11 (via https://pubmed.ncbi.nlm.nih.gov/34114711/)
Viruses are often cultured in cell lines for research and vaccine development, and those often differ from the natural hosts or tissues. Cell lines can also differ in the presence of virus receptors, such ... Ziebert F, Kuli? IM. How Influenza´s Spike Motor Works. Phys Rev Lett. 2021 May 28;126(21):218101. Abstract
submitted by kickingbird at Jun, 12, 2021 from Phys Rev Lett. 2021 May 28;126(21):218101 (via https://journals.aps.org/prl/abstract/10.1103/PhysRevLett.12)
While often believed to be a passive agent that merely exploits its host's metabolism, the influenza virus has recently been shown to actively move across glycan-coated surfaces. This form of enzymatically ... Shingai M, Nomura N, Sekiya T, Ohno M, Fujikura D,. Potent priming by inactivated whole influenza virus particle vaccines is linked to viral RNA uptake into antigen presenting cells. Vaccine. 2021 Jun 2:S0264-410X(21)00660-5. Abstract
submitted by kickingbird at Jun, 8, 2021 from Vaccine. 2021 Jun 2:S0264-410X(21)00660-5 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Current detergent or ether-disrupted split vaccines (SVs) for influenza do not always induce adequate immune responses, especially in young children. This contrasts with the whole virus particle vaccines ... 8128 items, 20/Page, Page[117/407][|<<] [|<] [111] [112] [113] [114] [115] [116] [117] [118] [119] [120] [>|] [>>|] |
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