Wang Y, Zhang X, Bi K, Diao H. Critical role of microRNAs in host and influenza A (H1N1) virus interactions. Life Sci. 2021 Apr 13:119484. Abstract
submitted by kickingbird at Apr, 18, 2021 from Life Sci. 2021 Apr 13:119484 (via https://www.sciencedirect.com/science/article/abs/pii/S00243)
As a type of non-coding RNA, microRNAs are considered to be a new regulator in viral infections. Influenza A (H1N1) virus infection is a serious threat to human health. There is growing evidence supporting ... Liu WJ, Xiao H, Dai L, Liu D, Chen J, Qi X, Bi Y,. Avian influenza A (H7N9) virus: from low pathogenic to highly pathogenic. Front Med. 2021 Apr 16.. Abstract
submitted by kickingbird at Apr, 18, 2021 from Front Med. 2021 Apr 16. (via https://pubmed.ncbi.nlm.nih.gov/33860875/)
The avian influenza A (H7N9) virus is a zoonotic virus that is closely associated with live poultry markets. It has caused infections in humans in China since 2013. Five waves of the H7N9 influenza epidemic ... Chiem K, López-García D, Ortego J, Martinez-Sobrid. Identification of amino acid residues required for inhibition of host gene expression by influenza A/Viet Nam/1203/2004 H5N1 PA-X. J Virol. 2021 Apr 14:JVI.00408-21. Abstract
submitted by kickingbird at Apr, 16, 2021 from J Virol. 2021 Apr 14:JVI.00408-21 (via https://jvi.asm.org/content/early/2021/04/08/JVI.00408-21)
PA-X is a non-structural protein of influenza A virus (IAV), which is encoded by the polymerase acidic (PA) N-terminal region that contains a C-terminal +1 frameshifted sequence. IAV PA-X protein modulates ... Zhirnov OP, Chlanda P. The cleavage of spike protein НА0→НА1/HA2 by trypsin permits activation of the M2 channel without its proteolytic cleavage in the influenza A virus. Virology. 2021 Apr 1;559:86-88. Abstract
submitted by kickingbird at Apr, 14, 2021 from Virology. 2021 Apr 1;559:86-88 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
M2 plays numerous regulatory roles in influenza A virus infection confirming the old adage: "a little body often harbors a great sense". The comment here demonstrates that a small viral protein M2, having ... Khan A, Jahejo AR, Qiao ML, Han XY, Cheng QQ, Mang. NF-кB pathway genes expression in chicken erythrocytes infected with Avian Influenza virus subtype H9N2. Br Poult Sci. 2021 Apr 12. Abstract
submitted by kickingbird at Apr, 14, 2021 from Br Poult Sci. 2021 Apr 12 (via https://www.tandfonline.com/doi/abs/10.1080/00071668.2021.19)
1. Chicken erythrocytes in blood vessels are the most abundant circulating cells, which participate in the host's immune responses. The transcription factor nuclear factor kappa B (NF-κB) plays a vital ... Seekings AH, Warren CJ, Thomas SS, Mahmood S, Jame. Highly pathogenic avian influenza virus H5N6 (clade 2.3.4.4b) has a preferable host tropism for waterfowl reflected in its inefficient transmission to terrestrial poultry. Virology. 2021 Mar 25;559:74-85. Abstract
submitted by kickingbird at Apr, 13, 2021 from Virology. 2021 Mar 25;559:74-85 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Highly-pathogenic avian influenza virus (HPAIV) H5N6 (clade 2.3.4.4b) incurred into Europe in late 2017 and was predominantly detected in wild birds, with very few terrestrial poultry cases. Pekin ducks ... Zhang X, Li Y, Jin S, Zhang Y, Sun L, Hu X, Zhao M. PB1 S524G mutation of wild bird-origin H3N8 influenza A virus enhances virulence and fitness for transmission in mammals. Emerg Microbes Infect. 2021 Apr 12:1-46. Abstract
submitted by kickingbird at Apr, 13, 2021 from Emerg Microbes Infect. 2021 Apr 12:1-46 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2021.1)
Influenza H3N8 viruses have been recovered frequently from wild bird species， including Anseriformes (primarily from migratory ducks) and Charadriiformes (primarily from shorebirds). However, little attention ... Tu YH, Guo Y, Ji S, Shen JL, Fei GH. The Influenza A Virus H3N2 Triggers the Hypersusceptibility of Airway Inflammatory Response via Activating the lncRNA TUG1/miR-145-5p/NF-κB Pathway in COPD. Front Pharmacol. 2021 Feb 22;12:604590. Abstract
submitted by kickingbird at Apr, 13, 2021 from Front Pharmacol. 2021 Feb 22;12:604590 (via https://www.frontiersin.org/articles/10.3389/fphar.2021.6045)
Background: Patients with chronic obstructive pulmonary disease (COPD) are more susceptible to influenza A virus (IAV) with more severe symptoms, yet the underlying molecular mechanisms of the hypersusceptibility ... Chaudhry M, Rashid HB, Thrusfield M, Eisler MC, We. Serosurvey of Avian Influenza Viruses (H5, H7, and H9) and Associated Risk Factors in Backyard Poultry Flocks of Lahore District, Pakistan. Front Vet Sci. 2021 Mar 24;8:631164. Abstract
submitted by kickingbird at Apr, 13, 2021 from Front Vet Sci. 2021 Mar 24;8:631164 (via https://www.frontiersin.org/articles/10.3389/fvets.2021.6311)
Rural poultry constitutes 56% of the total poultry population in Pakistan; however, epidemiological information about avian influenza viruses (AIVs) in backyard poultry flocks is lacking. A cross-sectional ... Deng J, Lu C, Liu C, Oveissi S, Fairlie WD, Lee EF. Influenza A virus infection-induced macroautophagy facilitates MHC class II-restricted endogenous presentation of an immunodominant viral epitope. FEBS J. 2020 Dec 5. Abstract
submitted by kickingbird at Apr, 12, 2021 from FEBS J. 2020 Dec 5 (via https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.15654)
CD4+ T cells recognize peptides presented by major histocompatibility complex class II molecules (MHC-II). These peptides are generally derived from exogenous antigens. Macroautophagy has been reported ... Bartley JM, Cadar AN, Martin DE. Better, Faster, Stronger: mRNA Vaccines Show Promise for Influenza Vaccination in Older Adults. Immunol Invest. 2021 Apr 8:1-11. Abstract
submitted by kickingbird at Apr, 12, 2021 from Immunol Invest. 2021 Apr 8:1-11 (via https://www.tandfonline.com/doi/abs/10.1080/08820139.2021.19)
Older adults have diminished immune responses that lead to increased susceptibility and severity of infectious diseases. Influenza is a leading killer of older adults despite the availability of seasonal ... Wei C, Qian F, Liu Y, Maione L, Hsu HC, Hsu WT, Le. Impact of obesity on influenza compared to pneumonia hospitalization outcomes. Obes Res Clin Pract. 2021 Apr 5:S1871-403X(21)0005. Abstract
submitted by kickingbird at Apr, 12, 2021 from Obes Res Clin Pract. 2021 Apr 5:S1871-403X(21)0005 (via https://www.sciencedirect.com/science/article/abs/pii/S18714)
Objectives: Previous literature has suggested that obesity impacts mortality risk differently in bacterial versus viral infections. This study sought to further elucidate this association in pneumonia ... Li X, Lv X, Li Y, Peng P, Zhou R, Qin S, Ma E, Liu. Highly Pathogenic Avian Influenza A(H5N8) Virus in Swans, China, 2020. Emerg Infect Dis. 2021 Apr 9;27(6). Abstract
submitted by kickingbird at Apr, 12, 2021 from Emerg Infect Dis. 2021 Apr 9;27(6) (via https://wwwnc.cdc.gov/eid/article/27/6/20-4727_article)
In October 2020, highly pathogenic avian influenza A(H5N8) viruses were detected in 2 dead swans in Inner Mongolia, China. Genetic analysis showed that the H5N8 isolates belong to clade 2.3.4.4b and that ... Qi Y, Guo W, Liu C, Li S, Chen X. Maternal transfer of antibodies specific for avian influenza viruses in captive whooper swans (Cygnus cygnus). Comp Immunol Microbiol Infect Dis. 2021 Apr 2;76:1. Abstract
submitted by kickingbird at Apr, 12, 2021 from Comp Immunol Microbiol Infect Dis. 2021 Apr 2;76:1 (via https://www.sciencedirect.com/science/article/abs/pii/S01479)
The transfer of maternal antibodies to offspring can effectively protect against avian influenza virus (AIV) infection during early life in chickens and can prevent AIV spread by decreasing the overall ... Sato M, Takashita E, Katayose M, Nemoto K, Sakai N. Detection of variants with reduced baloxavir marboxil and oseltamivir susceptibility in children with influenza A during the 2019-2020 influenza season. J Infect Dis. 2021 Apr 10:jiab196. Abstract
submitted by kickingbird at Apr, 12, 2021 from J Infect Dis. 2021 Apr 10:jiab196 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
Background: We aimed to detect influenza variants with reduced susceptibility to baloxavir marboxil (baloxavir) and oseltamivir and identify differences in the clinical course between children with and ... Sempere Borau M, Stertz S. Entry of influenza A virus into host cells - recent progress and remaining challenges. Curr Opin Virol. 2021 Apr 7;48:23-29. Abstract
submitted by kickingbird at Apr, 12, 2021 from Curr Opin Virol. 2021 Apr 7;48:23-29 (via https://www.sciencedirect.com/science/article/pii/S187962572)
Influenza A viruses (IAV) are a major burden for human health and thus the topic of intense research efforts. The entry of IAV into host cells is of particular interest as early infection steps are the ... Li G, Wang X, Li Q, Yang J, Liu X, Qi W, Guo J, De. Development of an immunochromatographic strip for rapid detection of H7 subtype avian influenza viruses. Virol J. 2021 Apr 7;18(1):68. Abstract
submitted by kickingbird at Apr, 9, 2021 from Virol J. 2021 Apr 7;18(1):68 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: H7N9 avian influenza virus (AIV) including highly and low pathogenic viruses have been detected in China since 2013. H7N9 AIV has a high mortality rate after infection in humans, and most human ... Zheng J, Wen L, Yen HL, Liu M, Liu Y, Teng O, Wu W. Phenotypic and functional characteristics of a novel influenza hemagglutinin-specific memory NK cell. J Virol. 2021 Apr 7:JVI.00165-21. Abstract
submitted by kickingbird at Apr, 9, 2021 from J Virol. 2021 Apr 7:JVI.00165-21 (via https://jvi.asm.org/content/early/2021/04/02/JVI.00165-21)
Immune memory represents the most efficient defense against invasion and transmission of infectious pathogens. In contrast to memory T and B cells, the roles of innate immunity in recall responses remain ... Mori K, Ohniwa RL, Takizawa N, Naito T, Saito M. Development of a Genetically Stable Live Attenuated Influenza Vaccine Strain using an Engineered High-Fidelity Viral Polymerase. J Virol. 2021 Apr 7:JVI.00493-21. Abstract
submitted by kickingbird at Apr, 9, 2021 from J Virol. 2021 Apr 7:JVI.00493-21 (via https://jvi.asm.org/content/early/2021/04/02/JVI.00493-21)
RNA viruses demonstrate a vast range of variants, called quasispecies, due to error-prone replication by viral RNA-dependent RNA polymerase. Although live attenuated vaccines are effective in preventing ... Giurgea LT, Park JK, Walters KA, Scherler K, Cerva. The effect of calcium and magnesium on activity, immunogenicity, and efficacy of a recombinant N1/N2 neuraminidase vaccine. NPJ Vaccines. 2021 Apr 6;6(1):48. Abstract
submitted by kickingbird at Apr, 8, 2021 from NPJ Vaccines. 2021 Apr 6;6(1):48 (via https://www.nature.com/articles/s41541-021-00310-x)
Despite the importance of immunity against neuraminidase (NA), NA content and immunogenicity are neglected in current influenza vaccines. To address this, a recombinant N1/N2 NA vaccine (NAV) was developed. ... 7725 items, 20/Page, Page[102/387][|<<] [|<] [101] [102] [103] [104] [105] [106] [107] [108] [109] [110] [>|] [>>|] |
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