Gong HH, Worley MJ, Carver KA, Godin CJ, Deng JC. Deficient neutrophil responses early in influenza infection promote viral replication and pulmonary inflammation. PLoS Pathog. 2025 Jan 17;21(1):e1012449. Abstract
submitted by kickingbird at Jan, 18, 2025 from PLoS Pathog. 2025 Jan 17;21(1):e1012449 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Neutrophils play key protective roles in influenza infections, yet excessive neutrophilic inflammation is a hallmark of acute lung injury during severe infections. Phenotypic heterogeneity is increasingly ... Teo QW, Wang Y, Lv H, Oade MS, Mao KJ, Tan TJC, Hu. Probing the functional constraints of influenza A virus NEP by deep mutational scanning. Cell Rep. 2025 Jan 14;44(1):115196. Abstract
submitted by kickingbird at Jan, 18, 2025 from Cell Rep. 2025 Jan 14;44(1):115196 (via https://www.cell.com/cell-reports/fulltext/S2211-1247(24)015)
The influenza A virus nuclear export protein (NEP) is a multifunctional protein that is essential for the viral life cycle and has very high sequence conservation. However, since the open reading frame ... Lambertucci, S.A., Santangeli, A. & Plaza, P.I. The threat of avian influenza H5N1 looms over global biodiversity. Nat. Rev. Biodivers. 1, 7–9 (2025). Abstract
submitted by kickingbird at Jan, 17, 2025 from Nat. Rev. Biodivers. 1, 7–9 (2025) (via https://link.springer.com/article/10.1038/s44358-024-00008-7)
The highly pathogenic avian influenza H5N1 is an emerging and unexpected threat to many wild animal species, which has implications for ecological processes, ecosystem services and conservation of threatened ... Yang, L., Fan, M. Reaction-advection-diffusion model of highly pathogenic avian influenza with behavior of migratory wild birds. J. Math. Biol. 90, 18 (2025). Abstract
submitted by kickingbird at Jan, 17, 2025 from J. Math. Biol. 90, 18 (2025) (via https://link.springer.com/article/10.1007/s00285-024-02181-x)
Wild birds are one of the main natural reservoirs for avian influenza viruses, and their migratory behavior significantly influences the transmission of avian influenza. To better describe the migratory ... Xue, Ruixue, Ma, Huiling, Jiang, Zixin, Xing, Linl. Diversity of the H9N2 Avian Influenza Virus in Shandong Province, China. Transboundary and Emerging Diseases, 2025, 1432483. Abstract
submitted by kickingbird at Jan, 17, 2025 from Transboundary and Emerging Diseases, 2025, 1432483 (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/1432483)
H9N2 avian influenza virus (AIV) is one of the main pathogens causing respiratory disease in chicken; however, differentiating this virus from infectious bronchitis virus (IBV) and newcastle disease virus ... Ma W, Ren C, Shi L, Meng B, Feng Y, Zhang Y. Isoleucine at position 137 of Hemagglutinin acts as a Mammalian adaptation marker of H9N2 Avian influenza virus. Emerg Microbes Infect. 2025 Jan 16:2455597. Abstract
submitted by kickingbird at Jan, 17, 2025 from Emerg Microbes Infect. 2025 Jan 16:2455597 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
The H9N2 subtype of avian influenza virus (AIV) is widely distributed among poultry and wild birds and is also a threat to humans. During AIV active surveillance in Liaoning province from 2015 to 2016, ... Goel V, Ding J, Hatuwal B, Giri E, Deliberto TJ, L. Ecological Drivers of Evolution of Swine Influenza in the United States: A Review. Emerg Microbes Infect. 2025 Jan 16:2455598. Abstract
submitted by kickingbird at Jan, 17, 2025 from Emerg Microbes Infect. 2025 Jan 16:2455598 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Influenza A viruses (IAVs) pose a major public health threat due to their wide host range and pandemic potential. Pigs have been proposed as "mixing vessels" for avian, swine, and human IAVs, significantly ... Rosenke, K., Giffin, A., Kaiser, F. et al. Pathogenesis of bovine H5N1 clade 2.3.4.4b infection in Macaques. Nature (2025). Abstract
submitted by kickingbird at Jan, 16, 2025 from Nature (2025) (via https://www.nature.com/articles/s41586-025-08609-8)
Since early 2022 highly pathogenic avian influenza (HPAI) H5N1 virus infections have been reported in wild aquatic birds and poultry throughout the United States (US) with spillover into several mammalian ... Victoria Meliopoulos, etc.,al. [preprint]Susceptibility of bovine respiratory and mammary epithelial cells to avian and mammalian derived clade 2.3.4.4b H5N1 highly pathogenic avian influenza viruses. https://doi.org/10.1101/2025.01.09.632235. Abstract
submitted by kickingbird at Jan, 15, 2025 from https://doi.org/10.1101/2025.01.09.632235 (via https://www.biorxiv.org/content/10.1101/2025.01.09.632235v1)
Zoonotic transmission of avian influenza viruses into mammals is relatively rare due to anatomical differences in the respiratory tract between species. Recently, clade 2.3.4.4b highly pathogenic H5N1 ... LI Shan, DONG Hui, YAO Xue, et al. Genetic Diversity of H10N3 Avian Influenza Virus Isolated from Anhui Province, China. Chin J Virol, 2024, 40(05): 1022-1032. Abstract
submitted by kickingbird at Jan, 15, 2025 from Chin J Virol, 2024, 40(05): 1022-1032
In April 2021，the first human case of infection by the H10N3 subtype avian influenza virus (AIV)was identified in Jiangsu，China. The genetic diversity and molecular characterizations of H10N3 subtype AIV ... WANG Shenjiao, QI Xian, YU Huiyan, DENG Fei, HUANG. Molecular origion of human infection with a novel avian influenza A H10N3 virus in China, 2021. Microbiology China, 2023, 50(3): 1231-1244.. Abstract
submitted by kickingbird at Jan, 15, 2025 from Microbiology China, 2023, 50(3): 1231-1244. (via http://journals.im.ac.cn/wswxtbcn)
[Background] Since the human infection with avian influenza that occurred in Hong Kong in 1997, avian influenza virus has become a major threat to human health and public health. [Objective] To perform ... Hawman, D.W., Tipih, T., Hodge, E. et al. Clade 2.3.4.4b but not historical clade 1 HA replicating RNA vaccine protects against bovine H5N1 challenge in mice. Nat Commun 16, 655 (2025). Abstract
submitted by kickingbird at Jan, 15, 2025 from Nat Commun 16, 655 (2025) (via https://link.springer.com/article/10.1038/s41467-024-55546-7)
The ongoing circulation of influenza A H5N1 in the United States has raised concerns of a pandemic caused by highly pathogenic avian influenza. Although the United States has stockpiled and is prepared ... Zou, J., Jiang, M., Xiao, R. et al. GGCX promotes Eurasian avian-like H1N1 swine influenza virus adaption to interspecies receptor binding. Nat Commun 16, 670 (2025). Abstract
submitted by kickingbird at Jan, 15, 2025 from Nat Commun 16, 670 (2025) (via https://link.springer.com/article/10.1038/s41467-025-55903-0)
The Eurasian avian-like (EA) H1N1 swine influenza virus (SIV) possesses the capacity to instigate the next influenza pandemic, owing to its heightened affinity for the human-type α-2,6 sialic acid (SA) ... Zhuanli Wu, Chengcheng Zhao, etc.,al. A Susceptible Cell-Selective Delivery (SCSD) of mRNA-Encoded Cas13d Against Influenza Infection. Advanced Science (2025). Abstract
submitted by kickingbird at Jan, 15, 2025 from Advanced Science (2025) (via https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.20)
To bolster the capacity for managing potential infectious diseases in the future, it is critical to develop specific antiviral drugs that can be rapidly designed and delivered precisely. Herein, a CRISPR/Cas13d ... Zhao C, Zhang X, Wang H, Qiang H, Liu S, Zhang C,. Proteomic Analysis of Differentially Expressed Proteins in A549 Cells Infected with H9N2 Avian Influenza Virus. International Journal of Molecular Sciences. 2025;. Abstract
submitted by kickingbird at Jan, 15, 2025 from International Journal of Molecular Sciences. 2025; (via https://www.mdpi.com/1422-0067/26/2/657)
Influenza A viruses (IAVs) are highly contagious pathogens that cause zoonotic disease with limited availability of antiviral therapies, presenting ongoing challenges to both public health and the livestock ... Liu S, Lin M, Zhou X. T4 Phage Displaying Dual Antigen Clusters Against H3N2 Influenza Virus Infection. Vaccines. 2025; 13(1):70. Abstract
submitted by kickingbird at Jan, 15, 2025 from Vaccines. 2025; 13(1):70 (via https://www.mdpi.com/2076-393X/13/1/70)
Background: The current H3N2 influenza subunit vaccine exhibits weak immunogenicity, which limits its effectiveness in preventing and controlling influenza virus infections. Methods: In this study, we ... Zhimin Wan, etc.,al. Identification of key antigenic sites in hemagglutinin of H10N3 avian influenza virus. Poultry Science (2024). Abstract
submitted by kickingbird at Jan, 15, 2025 from Poultry Science (2024) (via https://www.sciencedirect.com/science/article/pii/S003257912)
The H10 avian influenza viruses (AIV) have been detected in both birds and mammals. Recently, the cases of human infection with H10N8 and H10N3 in China pose high risk to public health. However, the antigenic ... Martins RP, Marc D, Germon P, Trapp S, Caballero-P. Influenza A virus in dairy cattle: infection biology and potential mammary gland-targeted vaccines. NPJ Vaccines. 2025 Jan 14;10(1):8. Abstract
submitted by kickingbird at Jan, 14, 2025 from NPJ Vaccines. 2025 Jan 14;10(1):8 (via https://www.nature.com/articles/s41541-025-01063-7)
Influenza, a major "One Health" threat, has gained heightened attention following recent reports of highly pathogenic avian influenza in dairy cattle and cow-to-human transmission in the USA. This review ... Yang J, Qureshi M, Kolli R, Peacock TP, Sadeyen JR. The Haemagglutinin Gene of Bovine-Origin H5N1 Influenza Viruses Currently Retains Receptor-binding and pH-fusion Characteristics of Avian Host Phenotype. Emerg Microbes Infect. 2025 Jan 13:2451052. Abstract
submitted by kickingbird at Jan, 14, 2025 from Emerg Microbes Infect. 2025 Jan 13:2451052 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus (HPAIV) has caused a panzootic affecting all continents except Australia, expanding its host range to several mammalian species. In March 2024, ... Lv X, Zheng T, Lei X, Ren L, Zhao S, Wang J, Zhuo. RTP4 restricts influenza A virus infection by targeting the viral NS1 protein. Virology. 2025 Jan 7;603:110397. Abstract
submitted by kickingbird at Jan, 13, 2025 from Virology. 2025 Jan 7;603:110397 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
The influenza A virus evades the host innate immune response to establish infection by inhibiting RIG-I activation through its nonstructural protein 1 (NS1). Here, we reported that receptor-transporting ... 5856 items, 20/Page, Page[9/293][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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