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2021-1-25 14:49:58
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Jiang W, Li Z, Liu S, et al. Genetic characterization of a highly pathogenic H5N6 avian influenza virus isolated from greylag goose. J Infect. 2020;S0163-4453(20)30550-8.  Abstract  
submitted by kickingbird at Aug, 18, 2020 from J Infect. 2020;S0163-4453(20)30550-8 (via https://pubmed.ncbi.nlm.nih.gov/32800799/)
We isolated and characterized a highly pathogenic H5N6 avian influenza virus in wild birds during avian influenza virus surveillance in 2020. The GG1/H5N6 virus was highly pathogenic. Several mutations ...

Yuyun I, Wibawa H, Setiaji G, Kusumastuti TA, Nugr. Determining highly pathogenic H5 avian influenza clade 2.3.2.1c seroprevalence in ducks, Purbalingga, Central Java, Indonesia. Vet World . 2020 Jun;13(6):1138-1144.  Abstract  
submitted by kickingbird at Aug, 18, 2020 from Vet World . 2020 Jun;13(6):1138-1144 (via https://pubmed.ncbi.nlm.nih.gov/32801565/)
Background and aim: In Indonesia, highly pathogenic avian influenza (HPAI) H5N1 outbreaks in poultry are still reported. The disease causes a decrease in egg production and an increase in mortality; this ...

Weinan Zheng, et al. Nucleoprotein phosphorylation site (Y385) mutation confers temperature sensitivity to influenza A virus due to impaired nucleoprotein oligomerization at a lower temperature. Sci China Life Sci . 2020 Aug 11.  Abstract  
submitted by kickingbird at Aug, 18, 2020 from Sci China Life Sci . 2020 Aug 11 (via https://pubmed.ncbi.nlm.nih.gov/32803713/)
Mutations in viral proteins can lead to the cold adaption of influenza A virus and the cold-adapted virus is an important vaccination instrument. Here, we identify a novel strain of influenza A virus with ...

Ming Zhong, et al. Amide-sialoside protein conjugates as neomucin bioshields prevent influenza virus infection. Carbohydr Res . 2020 Sep;495:108088..  Abstract  
submitted by kickingbird at Aug, 18, 2020 from Carbohydr Res . 2020 Sep;495:108088. (via https://pubmed.ncbi.nlm.nih.gov/32807356/)
We report the preparation of multivalent amide-sialoside-decorated human serum albumin (HSA) and bovine serum albumin (BSA) as mimics of natural mucin and bioshields against influenza virus infection. ...

Zhang M, Zhao C, Chen H, et al. Internal Gene Cassette From a Human-Origin H7N9 Influenza Virus Promotes the Pathogenicity of H9N2 Avian Influenza Virus in Mice. Front Microbiol. 2020;11:1441.  Abstract  
submitted by kickingbird at Aug, 17, 2020 from Front Microbiol. 2020;11:1441 (via https://pubmed.ncbi.nlm.nih.gov/32793127/)
H9N2 avian influenza virus is one of the most widely circulating viruses in poultry and poses a huge potential threat to human health due to its frequent gene reassortment with other influenza viruses. ...

Fay EJ, Aron SL, Macchietto MG, et al. Cell type- and replication stage-specific influenza virus responses in vivo. PLoS Pathog. 2020;16(8):e1008760.  Abstract  
submitted by kickingbird at Aug, 17, 2020 from PLoS Pathog. 2020;16(8):e1008760 (via https://pubmed.ncbi.nlm.nih.gov/32790753/)
Influenza A viruses (IAVs) remain a significant global health burden. Activation of the innate immune response is important for controlling early virus replication and spread. It is unclear how early IAV ...

Lim K, Kodera N, Wang H, et al. High-Speed AFM Reveals Molecular Dynamics of Human Influenza A Hemagglutinin and Its Interaction with Exosomes. Nano Lett. 2020;10.1021/acs.nanolett.0c01755.  Abstract  
submitted by kickingbird at Aug, 14, 2020 from Nano Lett. 2020;10.1021/acs.nanolett.0c01755 (via https://pubmed.ncbi.nlm.nih.gov/32787163/)
Influenza A hemagglutinin (HA) is one of the crucial virulence factors that mediate host tropism and viral infectivity. Presently, the mechanism of the fusogenic transition of HA remains elusive. Here, ...

Liang WS, He YC, Wu HD, et al. Ecological factors associated with persistent circulation of multiple highly pathogenic avian influenza viruses among poultry farms in Taiwan during 2015~17. PLoS One. 2020;15(8):e0236581.  Abstract  
submitted by kickingbird at Aug, 14, 2020 from PLoS One. 2020;15(8):e0236581 (via https://pubmed.ncbi.nlm.nih.gov/32790744/)
Emergence and intercontinental spread of highly pathogenic avian influenza A (HPAI) H5Nx virus clade 2.3.4.4 has resulted in substantial economic losses to the poultry industry in Asia, Europe, and North ...

Liu K, Gao R, Wang X, et al. Pathogenicity and transmissibility of clade 2.3.4.4 highly pathogenic avian influenza virus subtype H5N6 in pigeons. Vet Microbiol. 2020;247:108776.  Abstract  
submitted by kickingbird at Aug, 10, 2020 from Vet Microbiol. 2020;247:108776 (via https://pubmed.ncbi.nlm.nih.gov/32768222/)
Pigeons were previously thought to be resistant to H5 viruses and to play a minimal role in spreading these viruses. In this study, we evaluated the pathogenicity of two clade 2.3.4.4 H5N6 viruses in pigeons ...

Lycett SJ, Pohlmann A, Staubach C, et al. Genesis and spread of multiple reassortants during the 2016/2017 H5 avian influenza epidemic in Eurasia. Proc Natl Acad Sci U S A. 2020;202001813.  Abstract  
submitted by kickingbird at Aug, 10, 2020 from Proc Natl Acad Sci U S A. 2020;202001813 (via https://pubmed.ncbi.nlm.nih.gov/32769208/)
Highly pathogenic avian influenza (HPAI) viruses of the H5 A/goose/Guangdong/1/96 lineage can cause severe disease in poultry and wild birds, and occasionally in humans. In recent years, H5 HPAI viruses ...

Yu CM, Chen IC, Tung CP, et al. A panel of anti-influenza virus nucleoprotein antibodies selected from phage-displayed synthetic antibody libraries with rapid diagnostic capability to distinguish diverse influenza virus subtypes. Sci Rep. 2020;10(1):13318.  Abstract  
submitted by kickingbird at Aug, 10, 2020 from Sci Rep. 2020;10(1):13318 (via https://pubmed.ncbi.nlm.nih.gov/32770098/)
Immunoassays based on sandwich immuno-complexes of capture and detection antibodies simultaneously binding to the target analytes have been powerful technologies in molecular analyses. Recent developments ...

Diallo AA, Souley MM, Issa Ibrahim A, et al. Transboundary spread of equine influenza viruses (H3N8) in West and Central Africa: Molecular characterization of identified viruses during outbreaks in Niger and Senegal, in 2019. Transbound Emerg Dis. 2020;10.1111/tbed.13779.  Abstract  
submitted by kickingbird at Aug, 10, 2020 from Transbound Emerg Dis. 2020;10.1111/tbed.13779 (via https://pubmed.ncbi.nlm.nih.gov/32770642/)
Since November 2018, several countries in West and Central Africa have reported mortalities in donkeys and horses. Specifically, more than 66,000 horses and donkeys have succumbed to disease in Burkina ...

Yu L, Pan J, Cao G, et al. AIV polyantigen epitope expressed by recombinant baculovirus induces a systemic immune response in chicken and mouse models. Virol J. 2020;17(1):121.  Abstract  
submitted by kickingbird at Aug, 8, 2020 from Virol J. 2020;17(1):121 (via https://pubmed.ncbi.nlm.nih.gov/32758272/)
Background: The protective efficacy of avian influenza virus (AIV) vaccines is unsatisfactory due to the presence of various serotypes generated by genetic reassortment. Thus, immunization with a polyantigen ...

Guo F, Yang J, Pan J, et al. Origin and Evolution of H1N1/pdm2009: A Codon Usage Perspective. Front Microbiol. 2020;11:1615.  Abstract  
submitted by kickingbird at Aug, 8, 2020 from Front Microbiol. 2020;11:1615 (via https://pubmed.ncbi.nlm.nih.gov/32760376/)
The H1N1/pdm2009 virus is a new triple-reassortant virus. While Eurasian avian-like and triple-reassortant swine influenza viruses are the direct ancestors of H1N1/pdm2009, the classic swine influenza ...

Zhou L, Feng Z, Liu J, et al. A single N342D substitution in influenza B Virus NA protein determines viral pathogenicity in mice. Emerg Microbes Infect. 2020;1-35.  Abstract  
submitted by kickingbird at Aug, 5, 2020 from Emerg Microbes Infect. 2020;1-35 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2020.1)
Influenza B virus (IBV) is one of the most important human respiratory viruses: it causes approximately one-third of the global influenza-related disease burden each year. However, compared with the several ...

Kim SH, Choi JW, Kim AR, Lee SC, Yoon MY. Development of ssDNA Aptamers for Diagnosis and Inhibition of the Highly Pathogenic Avian Influenza Virus Subtype H5N1. Biomolecules. 2020;10(8):E1116.  Abstract  
submitted by kickingbird at Aug, 2, 2020 from Biomolecules. 2020;10(8):E1116 (via https://pubmed.ncbi.nlm.nih.gov/32731467/)
Avian influenza (AI) has severely affected the poultry industry worldwide and has caused the deaths of millions of birds. Highly pathogenic avian influenza virus is characterized by high mortality and ...

Zhang M, Huang Y, Godson DL, Fernando C, Alexander. Assessment of Metagenomic Sequencing and qPCR for Detection of Influenza D Virus in Bovine Respiratory Tract Samples. Viruses. 2020;12(8):E814.  Abstract  
submitted by kickingbird at Aug, 2, 2020 from Viruses. 2020;12(8):E814 (via https://pubmed.ncbi.nlm.nih.gov/32731471/)
High throughput sequencing is currently revolutionizing the genomics field and providing new approaches to the detection and characterization of microorganisms. The objective of this study was to assess ...

Dharmayanti NLPI, Hewajuli DA, Ratnawati A, Hartaw. Genetic diversity of the H5N1 viruses in live bird markets, Indonesia. J Vet Sci. 2020;21(4):e56.  Abstract  
submitted by kickingbird at Aug, 2, 2020 from J Vet Sci. 2020;21(4):e56 (via https://pubmed.ncbi.nlm.nih.gov/32735094/)
Background: The live bird market (LBM) plays an important role in the dynamic evolution of the avian influenza H5N1 virus. Objectives: The main objective of this study was to monitor the genetic diversity ...

Yang F, Xu L, Liu F, Yao H, Wu N, Wu H. Development and evaluation of a TaqMan MGB RT-PCR assay for detection of H5 and N8 subtype influenza virus. BMC Infect Dis. 2020;20(1):550.  Abstract  
submitted by kickingbird at Jul, 31, 2020 from BMC Infect Dis. 2020;20(1):550 (via https://pubmed.ncbi.nlm.nih.gov/32727378/)
Background: Highly pathogenic influenza A (H5N8) viruses have caused several worldwide outbreaks in birds and are of potential risk to humans. Thus, a specific, rapid and sensitive method for detection ...

Hernandez-Mejia G, Hernandez-Vargas EA. Uncovering antibody cross-reaction dynamics in influenza A infections. Bioinformatics. 2020;btaa691.  Abstract  
submitted by kickingbird at Jul, 31, 2020 from Bioinformatics. 2020;btaa691 (via https://pubmed.ncbi.nlm.nih.gov/32730562/)
Motivation: Influenza viruses are a cause of large outbreaks and pandemics with high death tolls. A key obstacle is that flu vaccines have inconsistent performance, in the best cases up to 60% effectiveness, ...

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