Daulagala P, Cheng SMS, Chin A, Luk LLH, Leung K,. Avian Influenza A(H5N1) Neuraminidase Inhibition Antibodies in Healthy Adults after Exposure to Influenza A(H1N1)pdm09. Emerg Infect Dis. 2024 Jan;30(1):168-171. Abstract
submitted by kickingbird at Dec, 27, 2023 from Emerg Infect Dis. 2024 Jan;30(1):168-171 (via https://wwwnc.cdc.gov/eid/article/30/1/23-0756_article)
We detected high titers of cross-reactive neuraminidase inhibition antibodies to influenza A(H5N1) virus clade 2.3.4.4b in 96.8% (61/63) of serum samples from healthy adults in Hong Kong in 2020. In contrast, ... Kristensen C, Larsen LE, Trebbien R, Jensen HE. The avian influenza A virus receptor SA-α2,3-Gal is expressed in the porcine nasal mucosa sustaining the pig as a mixing vessel for new influenza viruses. Virus Res. 2023 Dec 22:199304. Abstract
submitted by kickingbird at Dec, 25, 2023 from Virus Res. 2023 Dec 22:199304 (via https://pubmed.ncbi.nlm.nih.gov/38142890/)
Influenza A viruses (IAVs) originate from wild birds but have on several occasions jumped host barriers and are now also circulating in humans and mammals. The IAV host receptors (glycans with galactose ... Lean FZX, Falchieri M, Furman N, Tyler G, Robinson. Highly pathogenic avian influenza virus H5N1 infection in skua and gulls in the United Kingdom, 2022. Vet Pathol. 2023 Dec 23:3009858231217224. Abstract
submitted by kickingbird at Dec, 25, 2023 from Vet Pathol. 2023 Dec 23:3009858231217224 (via https://journals.sagepub.com/doi/10.1177/03009858231217224)
The reemergence of the highly pathogenic avian influenza virus (HPAIV) subtype H5N1 in the United Kingdom in 2021-2022 has caused unprecedented epizootic events in wild birds and poultry. During the summer ... Hickerson BT, Huang BK, Petrovskaya SN, Ilyushina. Genomic Analysis of Influenza A and B Viruses Carrying Baloxavir Resistance-Associated Substitutions Serially Passaged in Human Epithelial Cells. Viruses. 2023 Dec 16;15(12):2446. Abstract
submitted by kickingbird at Dec, 25, 2023 from Viruses. 2023 Dec 16;15(12):2446 (via https://www.mdpi.com/1999-4915/15/12/2446)
Baloxavir marboxil (baloxavir) is an FDA-approved inhibitor of the influenza virus polymerase acidic (PA) protein. Here, we used next-generation sequencing to compare the genomic mutational profiles of ... Wu R, Zeng X, Wu M, Xie L, Xu G, Mao Y, Wang Z, Ch. The Mobility of Eurasian Avian-like M2 Is Determined by Residue E79 Which Is Essential for Pathogenicity of 2009 Pandemic H1N1 Influenza Virus in Mice. Viruses. 2023 Nov 30;15(12):2365. Abstract
submitted by kickingbird at Dec, 25, 2023 from Viruses. 2023 Nov 30;15(12):2365 (via https://www.mdpi.com/1999-4915/15/12/2365)
In 2009, a novel H1N1 influenza virus caused the first influenza pandemic of the 21st century. Studies have shown that the influenza M gene played important roles in the pathogenicity and transmissibility ... Arbani O, Ducatez MF, Mahmoudi S, Salamat F, Khayi. Low Pathogenic Avian Influenza H9N2 Viruses in Morocco: Antigenic and Molecular Evolution from 2021 to 2023. Viruses. 2023 Nov 30;15(12):2355. Abstract
submitted by kickingbird at Dec, 25, 2023 from Viruses. 2023 Nov 30;15(12):2355 (via https://www.mdpi.com/1999-4915/15/12/2355)
Avian influenza viruses pose significant threats to both the poultry industry and public health worldwide. Among them, the H9N2 subtype has gained substantial attention due to its high prevalence, especially ... Sakuma S, Tanikawa T, Tsunekuni R, Mine J, Kumagai. Experimental Infection of Chickens with H5N8 High Pathogenicity Avian Influenza Viruses Isolated in Japan in the Winter of 2020-2021. Viruses. 2023 Nov 23;15(12):2293. Abstract
submitted by kickingbird at Dec, 25, 2023 from Viruses. 2023 Nov 23;15(12):2293 (via https://www.mdpi.com/1999-4915/15/12/2293)
During the winter of 2020-2021, numerous outbreaks of high pathogenicity avian influenza (HPAI) were caused by viruses of the subtype H5N8 in poultry over a wide region in Japan. The virus can be divided ... Sun X, Belser JA, Pulit-Penaloza JA, Brock N, Kier. A naturally occurring HA-stabilizing amino acid (HA1-Y17) in an A(H9N2) low-pathogenic influenza virus contributes to airborne transmission. mBio. 2023 Dec 19:e0295723. Abstract
submitted by kickingbird at Dec, 20, 2023 from mBio. 2023 Dec 19:e0295723 (via https://journals.asm.org/doi/10.1128/mbio.02957-23)
Despite the accumulation of evidence showing that airborne transmissible influenza A virus (IAV) typically has a lower pH threshold for hemagglutinin (HA) fusion activation, the underlying mechanism for ... Hu J, Zeng Z, Chen X, Zhang M, Hu Z, Gu M, Wang X,. Phosphorylation of PB2 at serine 181 restricts viral replication and virulence of the highly pathogenic H5N1 avian influenza virus in mice. Virol Sin. 2023 Dec 14:S1995-820X(23)00155-4. Abstract
submitted by kickingbird at Dec, 18, 2023 from Virol Sin. 2023 Dec 14:S1995-820X(23)00155-4 (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Influenza A virus (IAV) still poses a pandemic threat to public health, causing a high mortality rate annually and during pandemic years. Posttranslational modification of the viral protein plays a substantial ... Chenavier F, Estrozi LF, Teulon JM, Zarkadas E, Fr. Cryo-EM structure of influenza helical nucleocapsid reveals NP-NP and NP-RNA interactions as a model for the genome encapsidation. Sci Adv. 2023 Dec 15;9(50):eadj9974. Abstract
submitted by kickingbird at Dec, 17, 2023 from Sci Adv. 2023 Dec 15;9(50):eadj9974 (via https://www.science.org/doi/10.1126/sciadv.adj9974)
Influenza virus genome encapsidation is essential for the formation of a helical viral ribonucleoprotein (vRNP) complex composed of nucleoproteins (NP), the trimeric polymerase, and the viral genome. Although ... Dosey A, Ellis D, Boyoglu-Barnum S, Syeda H, Saund. Combinatorial immune refocusing within the influenza hemagglutinin RBD improves cross-neutralizing antibody responses. Cell Rep. 2023 Dec 13;42(12):113553. Abstract
submitted by kickingbird at Dec, 17, 2023 from Cell Rep. 2023 Dec 13;42(12):113553 (via https://www.cell.com/cell-reports/fulltext/S2211-1247(23)015)
The receptor-binding domain (RBD) of influenza virus hemagglutinin (HA) elicits potently neutralizing yet mostly strain-specific antibodies. Here, we evaluate the ability of several immunofocusing techniques ... Bialy D, Richardson S, Chrzastek K, Bhat S, Polo N. Recombinant A(H6N1)-H274Y avian influenza virus with dual drug resistance does not require permissive mutations to retain the replicative fitness in vitro and in ovo. Virology. 2023 Dec 2;590:109954. Abstract
submitted by kickingbird at Dec, 14, 2023 from Virology. 2023 Dec 2;590:109954 (via https://www.sciencedirect.com/science/article/pii/S004268222)
The possible emergence of drug-resistant avian flu raises concerns over the limited effectiveness of currently approved antivirals (neuraminidase inhibitors - NAIs) in the hypothetical event of a zoonotic ... Trov?o NS, Khan SM, Lemey P, Nelson MI, Cherry JL. Comparative evolution of influenza A virus H1 and H3 head and stalk domains across host species. mBio. 2023 Dec 11:e0264923. Abstract
submitted by kickingbird at Dec, 12, 2023 from mBio. 2023 Dec 11:e0264923 (via https://journals.asm.org/doi/10.1128/mbio.02649-23)
For decades, researchers have studied the rapid evolution of influenza A viruses for vaccine design and as a useful model system for the study of host/parasite evolution. By performing an exhaustive analysis ... Guan W, Qu R, Shen L, Mai K, Pan W, Lin Z, Chen L,. Baloxavir marboxil use for critical human infection of avian influenza A H5N6 virus. Med. 2023 Dec 5:S2666-6340(23)00361-6. Abstract
submitted by kickingbird at Dec, 11, 2023 from Med. 2023 Dec 5:S2666-6340(23)00361-6 (via https://www.cell.com/med/fulltext/S2666-6340(23)00361-6)
Background: Recent outbreaks of avian influenza and ongoing virus reassortment have drawn focus on spill-over infections. The increase in human infections with highly pathogenic avian influenza H5N6 virus ... Lijuan Liang, etc.,al. Genetic variation and evolution of influenza viruses isolated from co-infection cases in Guangdong Province. DOI: 10.3760/cma.j.cn112309-20230717-00213. Abstract
submitted by kickingbird at Dec, 11, 2023 from DOI: 10.3760/cma.j.cn112309-20230717-00213 (via https://rs.yiigle.com/cmaid/1482234)
Objective To analyze and reveal the genetic evolution and variation of influenza viruses in cases of co-infection in Guangdong Province.Methods Throat swab samples were collected from four cases of H1N1pdm ... Wang X, Zheng H, Gao R, Ren L, Jin M, Ji Z, Wang X. Genetically Related Avian Influenza H7N9 Viruses Exhibit Different Pathogenicity in Mice. Animals (Basel). 2023 Nov 28;13(23):3680. Abstract
submitted by kickingbird at Dec, 10, 2023 from Animals (Basel). 2023 Nov 28;13(23):3680 (via https://www.mdpi.com/2076-2615/13/23/3680)
Avian influenza viruses can cross species barriers and adapt to mammals. The H7N9 subtype AIV that emerged in China in 2013 caused 1568 human infections, with a mortality rate of nearly 40%. We conducted ... Zhao W, Liu X, Zhang X, Qiu Z, Jiao J, Li Y, Gao R. Virulence and transmission characteristics of clade 2.3.4.4b H5N6 subtype avian influenza viruses possessing different internal gene constellations. Virulence. 2023 Dec;14(1):2250065. Abstract
submitted by kickingbird at Dec, 9, 2023 from Virulence. 2023 Dec;14(1):2250065 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2023.2)
Clade 2.3.4.4 H5N6 avian influenza virus (AIV) has been predominant in poultry in China, and the circulating haemagglutinin (HA) gene has changed from clade 2.3.4.4h to clade 2.3.4.4b in recent years. ... Caceres CJ, Gay LC, Faccin FC, Pérez DR. Use of Reverse Genetics for the Generation of Recombinant Influenza Viruses Carrying Nanoluciferase. Methods Mol Biol. 2024;2733:47-74. Abstract
submitted by kickingbird at Dec, 9, 2023 from Methods Mol Biol. 2024;2733:47-74 (via https://link.springer.com/protocol/10.1007/978-1-0716-3533-9)
Influenza A (FLUAV) and influenza B (FLUBV) viruses are human and/or animal pathogens widely studied due to their importance to public health and animal production. Both FLUAV and FLUBV possess a genome ... Kessler S, García-Sastre A, Schwemmle M, Ciminski. Reverse Genetics of Bat Influenza A Viruses. Methods Mol Biol. 2024;2733:75-86. Abstract
submitted by kickingbird at Dec, 9, 2023 from Methods Mol Biol. 2024;2733:75-86 (via https://link.springer.com/protocol/10.1007/978-1-0716-3533-9)
New World fruit bats were recently found to harbor two distinct and previously unknown influenza A viruses (IAVs) of the subtypes H17N10 and H18N11. Although viral genome sequences were detected in the ... Zhang L, Shao Y, Wang Y, Yang Q, Guo J, Gao GF, De. Twenty natural amino acid substitution screening at the last residue 121 of influenza A virus NS2 protein reveals the critical role of NS2 in promoting virus genome replication by coordinating with vi. J Virol. 2023 Dec 6:e0116623. Abstract
submitted by kickingbird at Dec, 7, 2023 from J Virol. 2023 Dec 6:e0116623 (via https://journals.asm.org/doi/10.1128/jvi.01166-23)
The intrinsic mechanisms of influenza RNA polymerase (FluPol) in catalyzing viral genome transcription and replication have been largely resolved. However, the mechanisms of how transcription and replication ... 5147 items, 20/Page, Page[8/258][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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