Wang P, Zhu W, Liao B, Cai L, Peng L, Yang J. Predicting Influenza Antigenicity by Matrix Completion With Antigen and Antiserum Similarity. Front Microbiol. 2018 Oct 23;9:2500. Abstract
submitted by kickingbird at Nov, 11, 2018 from Front Microbiol. 2018 Oct 23;9:2500 (via https://www.ncbi.nlm.nih.gov/pubmed/30405563)
The rapid mutation of influenza viruses especially on the two surface proteins hemagglutinin (HA) and neuraminidase (NA) has made them capable to escape from population immunity, which has become a key ...
Qin J, Zhang Y, Shen X, Gong L, Xue C, Cao Y. Biological characteristics and immunological properties in Muscovy ducks of H5N6 virus-like particles composed of HA-TM/HA-TMH3 and M1. Avian Pathol. 2018 Nov 8:1-35. Abstract
submitted by kickingbird at Nov, 11, 2018 from Avian Pathol. 2018 Nov 8:1-35 (via https://www.ncbi.nlm.nih.gov/pubmed/30404538)
Highly pathogenic avian influenza viruses (HPAIVs), including H5N6 strains, pose threats to the health of humans and poultry. Waterfowl play a crucial role in HPAIVs. Since current influenza vaccines induce ...
Mayr J, et al. Unravelling the Role of O-glycans in Influenza A Virus Infection. Sci Rep. 2018 Nov 6;8(1):16382. Abstract
submitted by kickingbird at Nov, 11, 2018 from Sci Rep. 2018 Nov 6;8(1):16382 (via https://www.ncbi.nlm.nih.gov/pubmed/30401951)
The initial stage of host cell infection by influenza A viruses (IAV) is mediated through interaction of the viral haemagglutinin (HA) with cell surface glycans. The binding requirement of IAVs for Galβ(1,4)Glc/ ...
Rodriguez L, Nogales A, Iqbal M, Perez DR, et al. Identification of Amino Acid Residues Responsible for Inhibition of Host Gene Expression by Influenza A H9N2 NS1 Targeting of CPSF30. Front Microbiol. 2018 Oct 24;9:2546.. Abstract
submitted by kickingbird at Nov, 11, 2018 from Front Microbiol. 2018 Oct 24;9:2546. (via https://www.ncbi.nlm.nih.gov/pubmed/30405591)
H9N2 influenza A viruses (IAV) are considered low pathogenic avian influenza viruses (LPAIV). These viruses are endemic in poultry in many countries in Asia, the Middle East and parts of Africa. Several ...
Ma G, et al. Histone acetyl transferase TIP60 inhibits the replication of influenza a virus by activation the TBK1-IRF3 pathway. Virol J. 2018 Nov 8;15(1):172.. Abstract
submitted by kickingbird at Nov, 11, 2018 from Virol J. 2018 Nov 8;15(1):172. (via https://www.ncbi.nlm.nih.gov/pubmed/30409205)
Influenza A virus (IAV) is an important pathogen that poses a severe threat to the health of humans. Nucleoprotein (NP) of IAV plays crucial roles in the viral life cycle by interacting with various cellular ...
Lyu Y, Song S, Zhou L, Bing G, Wang Q, Sun Haoran,. Canine Influenza Virus A(H3N2) Clade with Antigenic Variation, China, 2016~2017. Emerg Infect Dis. 2019 Jan. Abstract
submitted by kickingbird at Nov, 10, 2018 from Emerg Infect Dis. 2019 Jan (via https://wwwnc.cdc.gov/eid/article/25/1/17-1878_article)
During 2012-2017, we collected throat swabs from dogs in China to characterize canine influenza virus (CIV) A(H3N2) isolates. A new antigenically and genetically distinct CIV H3N2 clade possessing mutations ...
Rudenko L, et al. Two Live Attenuated Vaccines against Recent Low and Highly Pathogenic H7N9 Influenza Viruses Are Safe and Immunogenic in Ferrets. Vaccines (Basel). 2018 Nov 1;6(4).. Abstract
submitted by kickingbird at Nov, 7, 2018 from Vaccines (Basel). 2018 Nov 1;6(4). (via https://www.ncbi.nlm.nih.gov/pubmed/30388790)
Influenza H7N9 virus is a potentially pandemic subtype to which most people are immunologically naive. To be better prepared for the potential occurrence of an H7N9 pandemic, in 2017 the World Health Organization ...
Moasser E, Moasser A, Zaraket H. Incidence of antiviral drug resistance markers among human influenza A viruses in the Eastern Mediterranean Region, 2005-2016. Infect Genet Evol. 2018 Oct 30;67:60-66.. Abstract
submitted by kickingbird at Nov, 7, 2018 from Infect Genet Evol. 2018 Oct 30;67:60-66. (via https://www.ncbi.nlm.nih.gov/pubmed/30389548)
BACKGROUND: Two classes of antiviral drugs are available for influenza antiviral therapy: the adamantanes and the neuraminidase inhibitors (NAIs). Due to the emergence of adamantane-resistant variants, ...
Nishisaka-Nonaka R. et al. Irradiation by ultraviolet light-emitting diodes inactivates influenza a viruses by inhibiting replication and transcription of viral RNA in host cells. J Photochem Photobiol B 2018. Abstract
submitted by kickingbird at Nov, 7, 2018 from J Photochem Photobiol B 2018 (via https://www.ncbi.nlm.nih.gov/pubmed/30391908)
Influenza A viruses (IAVs) pose a serious global threat to humans and their livestock, especially poultry and pigs. This study aimed to investigate how to inactivate IAVs by using different ultraviolet-light-emitting ...
Nicol MQ, et al. Lack of IFNγ signaling attenuates spread of influenza A virus in vivo and leads to reduced pathogenesis. Virology. 2018 Oct 31;526:155-164. Abstract
submitted by kickingbird at Nov, 7, 2018 from Virology. 2018 Oct 31;526:155-164 (via https://www.ncbi.nlm.nih.gov/pubmed/30390564)
IFNγ is a key regulator of inflammatory responses but its role in influenza A virus (IAV) pathogenesis is unclear. Our studies show that infection of mice lacking the IFNγ receptor (IFNγR-/-) at a dose ...
Matos AR, et al. Human CCR5Δ32 (rs333) polymorphism has no influence on severity and mortality of influenza A(H1N1)pdm09 infection in Brazilian patients from the post pandemic period. Infect Genet Evol. 2018 Oct 31;67:55-59. Abstract
submitted by kickingbird at Nov, 7, 2018 from Infect Genet Evol. 2018 Oct 31;67:55-59 (via https://www.ncbi.nlm.nih.gov/pubmed/30389547)
BACKGROUND: Influenza is an acute and highly contagious viral respiratory infection that causes significant morbidity and mortality. The identification of host genetic factors associated with susceptibility ...
Robertson CA, et al. Safety and Immunogenicity of a Full-Dose Split-Virion Inactivated Quadrivalent Influenza Vaccine in Healthy Children 6 to 35 Months of Age: A Randomized Controlled Clinical Trial. Pediatr Infect Dis J. 2018 Nov 2. Abstract
submitted by kickingbird at Nov, 7, 2018 from Pediatr Infect Dis J. 2018 Nov 2 (via https://www.ncbi.nlm.nih.gov/pubmed/30395011)
BACKGROUND: For children aged METHODS: In this phase IV, randomized, observer-blinded, multi-center study, healthy children aged 6 to 35 months were randomized 1:1 to be vaccinated with a half or full ...
Poirot E, et al. Detection of Avian Influenza A(H7N2) Virus Infection Among Animal Shelter Workers Using a Novel Serological Approach-New York City, 2016-2017. J Infect Dis. 2018 Nov 5.. Abstract
submitted by kickingbird at Nov, 7, 2018 from J Infect Dis. 2018 Nov 5. (via https://www.ncbi.nlm.nih.gov/pubmed/30395249)
Background: In 2016, an influenza A(H7N2) virus outbreak occurred in cats in New York City's municipal animal shelters. One human infection was initially detected.Methods: We conducted a serological survey ...
Hong ZY, et al. Equipping inner central components of influenza A virus with quantum dots. Anal Chem. 2018 Nov 5.. Abstract
submitted by kickingbird at Nov, 7, 2018 from Anal Chem. 2018 Nov 5. (via https://pubs.acs.org/doi/10.1021/acs.analchem.8b03995)
Influenza A virus (IAV), a risk to public health, is enveloped and contains viral ribonucleoprotein (vRNP) complexes, where vRNP complexes are centrality to every aspect of IAV life cycle. Labeling both ...
Shah P, Zaveri JS, Haddock LJ.. Acute Macular Neuroretinopathy Following the Administration of an Influenza Vaccination. Ophthalmic Surg Lasers Imaging Retina. Abstract
submitted by kickingbird at Nov, 7, 2018 from Ophthalmic Surg Lasers Imaging Retina (via https://www.ncbi.nlm.nih.gov/pubmed/30395681)
This manuscript reports a rare association of the development of acute macular neuroretinopathy (AMN) after administration of an influenza vaccination. A 42-year-old white female presented with a 2-week ...
Mohseni SS, et al. Identification of novel inhibitor against endonuclease subunit of Influenza pH1N1 polymerase: A combined molecular docking, molecular dynamics, MMPBSA, QMMM and ADME studies to combat influenza A viru. Comput Biol Chem. 2018 Aug 23;77:279-290. Abstract
submitted by kickingbird at Nov, 7, 2018 from Comput Biol Chem. 2018 Aug 23;77:279-290 (via https://www.ncbi.nlm.nih.gov/pubmed/30396155)
The influenza H1N1 virus is the causative agent of the flu pandemic in the world. Due to the shortage of effective means of control, it is remained the serious threats to public and avian health. To battle ...
Song JY, et al. Immunogenicity and safety of an egg-based inactivated quadrivalent influenza vaccine (GC3110A) versus two inactivated trivalent influenza vaccines with alternate B strains: A phase Ⅲ randomized clinic. Hum Vaccin Immunother. 2018 Nov 5. Abstract
submitted by kickingbird at Nov, 7, 2018 from Hum Vaccin Immunother. 2018 Nov 5 (via https://www.ncbi.nlm.nih.gov/pubmed/30396317)
Two antigenically distinct influenza B lineage viruses (Yamagata/Victoria) have been co-circulating globally since the mid-1980s. The quadrivalent influenza vaccine (QIV) may provide better protection ...
Il Kim J, et al. Distinct molecular evolution of influenza H3N2 strains in the 2016/17 season and its implications for vaccine effectiveness. Mol Phylogenet Evol. 2018 Nov 3.. Abstract
submitted by kickingbird at Nov, 7, 2018 from Mol Phylogenet Evol. 2018 Nov 3. (via https://www.ncbi.nlm.nih.gov/pubmed/30399431)
Influenza virus is a respiratory pathogen that causes seasonal epidemics by resulting in a considerable number of influenza-like illness (ILI) patients. During the 2016/17 season, ILI rates increased unusually ...
Alkie TN, Yitbarek A, Taha-Abdelaziz K, et al. Characterization of immunogenicity of avian influenza antigens encapsulated in PLGA nanoparticles following mucosal and subcutaneous delivery in chickens. PLoS One. 2018 Nov 1;13(11):e0206324. Abstract
submitted by kickingbird at Nov, 6, 2018 from PLoS One. 2018 Nov 1;13(11):e0206324 (via https://www.ncbi.nlm.nih.gov/pubmed/30383798)
Mucosal vaccine delivery systems have paramount importance for the induction of mucosal antibody responses. Two studies were conducted to evaluate immunogenicity of inactivated AIV antigens encapsulated ...
KyungHyun Lee, et al. Highly Pathogenic Avian Influenza A(H5N6) in Domestic Cats, South Korea. Emerg Infect Dis. 2018 Dec. Abstract
submitted by kickingbird at Nov, 3, 2018 from Emerg Infect Dis. 2018 Dec (via https://wwwnc.cdc.gov/eid/article/24/12/18-0290_article)
In December 2016, highly pathogenic avian influenza (HPAI) infection with systemic pathological lesions was found in cats in South Korea. Genetic analyses indicated that the feline isolates were similar ...
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