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2022-6-25 9:55:07

Zhao L, Li Y, Zhao Y, Liu Q, Lu Y, Ping J. SRSF3 facilitates replication of influenza A virus via binding and promoting the transport of viral mRNA. Vet Microbiol. 2022 Jan 17;266:109343.  Abstract  
submitted by kickingbird at Jan, 25, 2022 from Vet Microbiol. 2022 Jan 17;266:109343 (via https://www.sciencedirect.com/science/article/pii/S037811352)
Many host factors were involved in regulating the polymerase activity of influenza A virus. To fully explore the role of polymerase complex-related host factors, we combined high-throughput transcriptome ...

Aji D, Chang N, Zhang C, Du F, Li J, Yun F, Shi W,. Rapid Emergence of the Reassortant H5N2 Highly Pathogenic Avian Influenza Viruses in a Live Poultry Market in Xinjiang, Northwest China. Avian Dis. 2021 Dec;65(4):578-583.  Abstract  
submitted by kickingbird at Jan, 25, 2022 from Avian Dis. 2021 Dec;65(4):578-583 (via https://bioone.org/journals/avian-diseases/volume-65/issue-4)
Live poultry markets (LPMs) play a key role in reassorting and spreading avian influenza viruses (AIVs). In 2018, four strains of H5N2 AIVs were isolated from domestic ducks (Anas platyrhynchos) during ...

Gui R, Chen Q. Molecular Events Involved in Influenza A Virus-Induced Cell Death. Front Microbiol. 2022 Jan 7;12:797789.  Abstract  
submitted by kickingbird at Jan, 25, 2022 from Front Microbiol. 2022 Jan 7;12:797789 (via https://www.frontiersin.org/articles/10.3389/fmicb.2021.7977)
Viral infection usually leads to cell death. Moderate cell death is a protective innate immune response. By contrast, excessive, uncontrolled cell death causes tissue destruction, cytokine storm, or even ...

Chen L, Li G, Tian Y, Zeng T, Xu W, Gu T, Lu L. RNA Sequencing Reveals circRNA Expression Profiles in Chicken DF1 Cells Infected with H5N1 Influenza Virus. Animals (Basel). 2022 Jan 10;12(2):158.  Abstract  
submitted by kickingbird at Jan, 21, 2022 from Animals (Basel). 2022 Jan 10;12(2):158 (via https://www.mdpi.com/2076-2615/12/2/158/htm)
H5N1, a highly pathogenic avian influenza virus that is prevalent in Asia, seriously harms the poultry industry and global public health. However, its pathogenesis is still not well understood. Circular ...

Caliendo V, Leijten L, van de Bildt MWG, Fouchier. Pathology and virology of natural highly pathogenic avian influenza H5N8 infection in wild Common buzzards (Buteo buteo). Sci Rep. 2022 Jan 18;12(1):920.  Abstract  
submitted by kickingbird at Jan, 20, 2022 from Sci Rep. 2022 Jan 18;12(1):920 (via https://www.nature.com/articles/s41598-022-04896-7)
Highly pathogenic avian influenza (HPAI) in wild birds is a major emerging disease, and a cause of increased mortality during outbreaks. The Common buzzard (Buteo buteo) has a considerable chance of acquiring ...

Miyamoto S, Muramoto Y, Shindo K, Fujita-Fujiharu. Contribution of RNA-RNA interactions mediated by the genome packaging signals for the selective genome packaging of influenza A virus. J Virol. 2022 Jan 19:JVI0164121.  Abstract  
submitted by kickingbird at Jan, 20, 2022 from J Virol. 2022 Jan 19:JVI0164121 (via https://journals.asm.org/doi/10.1128/JVI.01641-21)
The influenza A virus genome is composed of eight single-stranded negative-sense RNA segments (vRNAs). The eight vRNAs are selectively packaged into each progeny virion. This process likely involves specific ...

Banerjee S, De A, Kedia N, Bhakta K, Wang L, Bhatt. The species-specific 282 residue in the PB2 subunit of the polymerase regulates RNA synthesis and replication of influenza A viruses infecting bat and non-bat hosts. J Virol. 2022 Jan 19:jvi0219021.  Abstract  
submitted by kickingbird at Jan, 20, 2022 from J Virol. 2022 Jan 19:jvi0219021 (via https://journals.asm.org/doi/10.1128/jvi.02190-21)
Bat influenza viruses are genetically distant from classical influenza A viruses (IAV) and show distinct functional differences in their surface antigens. Nevertheless, any comparative analysis between ...

Spruit CM, Zhu X, Tomris I, Carrasco MR, Han AX, B. N-glycolylneuraminic acid binding of avian and equine H7 influenza A viruses. J Virol. 2022 Jan 19:jvi0212021.  Abstract  
submitted by kickingbird at Jan, 20, 2022 from J Virol. 2022 Jan 19:jvi0212021 (via https://journals.asm.org/doi/10.1128/jvi.02120-21)
Influenza A viruses (IAV) initiate infection by binding to glycans with terminal sialic acids on the cell surface. Hosts of IAV variably express two major forms of sialic acid, N-acetylneuraminic acid ...

Yu M, Sun L, Zhang Z, Zhang Y, Zhang H, Na L, Wang. KPNA6 is a Cofactor of ANP32A/B in Supporting Influenza Virus Polymerase Activity. Microbiol Spectr. 2022 Jan 19:e0207321.  Abstract  
submitted by kickingbird at Jan, 20, 2022 from Microbiol Spectr. 2022 Jan 19:e0207321 (via https://journals.asm.org/doi/10.1128/spectrum.02073-21)
Influenza A virus (IAV) RNA-dependent RNA polymerase (vPol) is a heterotrimer composed of PB2, PB1, and PA, which, together with vRNA and nucleoprotein (NP), forms viral ribonucleoprotein (vRNP) complex ...

Jiang L, Samant N, Liu P, Somasundaran M, Jensen J. Identification of a permissive secondary mutation that restores the enzymatic activity of oseltamivir resistance mutation H275Y. J Virol. 2022 Jan 19:jvi0198221.  Abstract  
submitted by kickingbird at Jan, 20, 2022 from J Virol. 2022 Jan 19:jvi0198221 (via https://journals.asm.org/doi/10.1128/jvi.01982-21)
Many oseltamivir resistance mutations exhibit fitness defects in the absence of drug pressure that hinders their propagation in hosts. Secondary permissive mutations can rescue fitness defects and facilitate ...

Encinas P, Del Real G, Dutta J, Khan Z, van Bakel. Evolution of influenza A virus in intensive and free-range swine farms in Spain. Virus Evol. 2021 Nov 30;7(2):veab099.  Abstract  
submitted by kickingbird at Jan, 19, 2022 from Virus Evol. 2021 Nov 30;7(2):veab099 (via https://academic.oup.com/ve/article/7/2/veab099/6446465)
Swine harbor genetically diverse influenza A viruses (IAVs) with the capacity to host-switch to humans, causing global pandemics. Spain is the largest swine producer in Europe and has a mixed production ...

Gao X, Wang N, Chen Y, Gu X, Huang Y, Liu Y, Jiang. Sequence characteristics and phylogenetic analysis of H9N2 subtype avian influenza A viruses detected from poultry and the environment in China, 2018. PeerJ. 2021 Dec 20;9:e12512.  Abstract  
submitted by kickingbird at Jan, 18, 2022 from PeerJ. 2021 Dec 20;9:e12512 (via https://peerj.com/articles/12512/)
H9N2 subtype avian influenza A virus (AIV) is a causative agent that poses serious threats to both the poultry industry and global public health. In this study, we performed active surveillance to identify ...

Liu L, Li Z, Zhou J, Liu J, Li X, Huang W, Xiao N,. Homologous PB1 gene promotes the replication efficiency of avian influenza H7N4 candidate vaccine virus. Influenza Other Respir Viruses. 2022 Jan 17.  Abstract  
submitted by kickingbird at Jan, 18, 2022 from Influenza Other Respir Viruses. 2022 Jan 17 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.12954)
Background: The first and only case of human infection with the avian influenza A (H7N4) virus in China emerged in 2018. The H7N4 virus was distinct from previous H7N9 viruses and raised public concerns. ...

Peterson JM, O´Leary CA, Moss WN. In silico analysis of local RNA secondary structure in influenza virus A, B and C finds evidence of widespread ordered stability but little evidence of significant covariation. Sci Rep. 2022 Jan 10;12(1):310.  Abstract  
submitted by kickingbird at Jan, 13, 2022 from Sci Rep. 2022 Jan 10;12(1):310 (via https://www.nature.com/articles/s41598-021-03767-x)
Influenza virus is a persistent threat to human health; indeed, the deadliest modern pandemic was in 1918 when an H1N1 virus killed an estimated 50 million people globally. The intent of this work is to ...

Veler H, Fan H, Keown J, Sharps J, Fournier M, Gri. The C-terminal domains of the PB2 subunit of the influenza A virus RNA polymerase directly interact with cellular GTPase Rab11a. J Virol. 2022 Jan 12:jvi0197921.  Abstract  
submitted by kickingbird at Jan, 13, 2022 from J Virol. 2022 Jan 12:jvi0197921 (via https://journals.asm.org/doi/10.1128/jvi.01979-21)
Influenza A virus (IAV) contains a segmented RNA genome that is transcribed and replicated by the viral RNA polymerase in the cell nucleus. Replicated RNA segments are assembled with viral polymerase and ...

Rashid MU, Gao A, Coombs KM. Influenza A virus uses PSMA2 for downregulation of NRF2-mediated oxidative stress response. J Virol. 2022 Jan 12:jvi0199021.  Abstract  
submitted by kickingbird at Jan, 13, 2022 from J Virol. 2022 Jan 12:jvi0199021 (via https://journals.asm.org/doi/10.1128/jvi.01990-21)
Influenza A virus (IAV), an obligatory intracellular parasite, uses host cellular molecules to complete its replication cycle and suppress immune responses. Proteasome subunit alpha type-2 (PSMA2) is a ...

Yan W, Cui H, Engelsma M, Beerens N, van Oers MM,. Molecular and Antigenic Characterization of Avian H9N2 Viruses in Southern China. Microbiol Spectr. 2022 Jan 12:e0082221.  Abstract  
submitted by kickingbird at Jan, 13, 2022 from Microbiol Spectr. 2022 Jan 12:e0082221 (via https://journals.asm.org/doi/10.1128/spectrum.00822-21)
The H9N2 subtype avian influenza virus (AIV) has become endemic in poultry globally; however due to its low pathogenicity, it is not under primary surveillance and control in many countries. Recent reports ...

Sharma A, Zeller MA, Souza CK, Anderson TK, Vincen. Characterization of a 2016-2017 Human Seasonal H3 Influenza A Virus Spillover Now Endemic to U.S. Swine. mSphere. 2022 Jan 12:e0080921.  Abstract  
submitted by kickingbird at Jan, 13, 2022 from mSphere. 2022 Jan 12:e0080921 (via https://journals.asm.org/doi/10.1128/msphere.00809-21)
In 2017, the Iowa State University Veterinary Diagnostic Laboratory detected a reverse-zoonotic transmission of a human seasonal H3 influenza A virus into swine (IAV-S) in Oklahoma. Pairwise comparison ...

Keown JR, Zhu Z, Carrique L, Fan H, Walker AP, Ser. Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies. Nat Commun. 2022 Jan 11;13(1):251.  Abstract  
submitted by kickingbird at Jan, 13, 2022 from Nat Commun. 2022 Jan 11;13(1):251 (via https://www.nature.com/articles/s41467-021-27950-w)
Influenza A viruses cause seasonal epidemics and global pandemics, representing a considerable burden to healthcare systems. Central to the replication cycle of influenza viruses is the viral RNA-dependent ...

Vu TH, Hong Y, Truong AD, Lee S, Heo J, Lillehoj H. The highly pathogenic H5N1 avian influenza virus induces the MAPK signaling pathway in the trachea of two Ri chicken lines. Anim Biosci. 2022 Jan 5.  Abstract  
submitted by kickingbird at Jan, 10, 2022 from Anim Biosci. 2022 Jan 5 (via https://www.animbiosci.org/journal/view.php?doi=10.5713/ab.2)
Objective: The highly pathogenic avian influenza virus (HPAIV) is a threat to the poultry industry and economy and remains a potential source of pandemic infection in humans. Antiviral genes are considered ...

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