Cha RM, Park MJ, Baek YG, Lee YN, Jang Y, Kang YM,. Genetic characteristics and pathogenesis of clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus isolated from poultry in South Korea, 2022-2023. Virus Res. 2025 Jan 31:199541. Abstract
submitted by kickingbird at Feb, 3, 2025 from Virus Res. 2025 Jan 31:199541 (via https://pubmed.ncbi.nlm.nih.gov/39894372/)
During the 2022-2023 winter season in South Korea, a novel clade 2.3.4.4b H5N1 HPAIV was first detected in wild birds, which then subsequently caused multiple outbreaks in poultry farms and wild birds. ... Kirkpatrick Roubidoux E, Meliopoulos V, Livingston. Intraductal infection with H5N1 clade 2.3.4.4b influenza virus. J Virol. 2025 Jan 31:e0192724. Abstract
submitted by kickingbird at Feb, 1, 2025 from J Virol. 2025 Jan 31:e0192724 (via https://journals.asm.org/doi/10.1128/jvi.01927-24)
In March 2024, highly pathogenic avian influenza (HPAI) H5N1 of the clade 2.3.4.4b was detected in dairy cows in Texas and has since been detected in several other U.S. states. Virus has been detected ... Beate M. Crossley, etc.,al. In laboratory inactivation of H5N1 in raw whole milk through milk acidification: results from a pilot study. Journal of Dairy Science. Abstract
submitted by kickingbird at Jan, 30, 2025 from Journal of Dairy Science (via https://www.sciencedirect.com/science/article/pii/S002203022)
Avian Influenza virus H5N1 2.3.4.4.b has recently been detected in cattle, with milk from infected animals reported to contain a high viral load, serving as a potential source for shedding and dissemination ... Nicholas C. Morano, etc.,al. Structure of a zoonotic H5N1 hemagglutinin reveals a receptor-binding site occupied by an auto-glycan. Structure, January 2025. Abstract
submitted by kickingbird at Jan, 30, 2025 from Structure, January 2025 (via https://www.sciencedirect.com/science/article/abs/pii/S09692)
Highly pathogenic avian influenza has spilled into many mammals, most notably cows and poultry, with several dozen human breakthrough infections. Zoonotic crossovers, with hemagglutinins mutated to enhance ... Huarui Duan, etc.,al. Computational design and improvement of a broad influenza virus HA stem targeting antibody. Structure, January 2025. Abstract
submitted by kickingbird at Jan, 30, 2025 from Structure, January 2025 (via https://www.sciencedirect.com/science/article/abs/pii/S09692)
Broadly neutralizing antibodies (nAbs) are vital therapeutic tools to counteract both pandemic and seasonal influenza threats. Traditional strategies for optimizing nAbs generally rely on labor-intensive, ... Nishiyama A, Nogimori T, Masuta Y, Matsuura T, Kas. Cross-Reactive Fc-Mediated Antibody Responses to Influenza HA Stem Region in Human Sera Following Seasonal Vaccination. Vaccines. 2025; 13(2):140. Abstract
submitted by kickingbird at Jan, 30, 2025 from Vaccines. 2025; 13(2):140 (via https://www.mdpi.com/2076-393X/13/2/140)
Background: Current influenza A vaccines primarily induce neutralizing antibodies targeting the variable hemagglutinin (HA) head domain, limiting their effectiveness against diverse or emerging influenza ... Thomas Rawson, etc.,al. [preprint]A mathematical model of H5N1 influenza transmission in US dairy cattle.. https://doi.org/10.1101/2025.01.28.25321250. Abstract
submitted by kickingbird at Jan, 30, 2025 from https://doi.org/10.1101/2025.01.28.25321250 (via https://www.medrxiv.org/content/10.1101/2025.01.28.25321250v)
We present a stochastic metapopulation transmission model that simulates the spread of H5N1 avian influenza through individual dairy cows in 35,974 dairy herds in the continental United States. Transmission ... Zhang L, Yang Q, Shao Y, Ding S, Guo J, Gao GF, De. Influenza A virus NS2 protein acts on vRNA-resident polymerase to drive the transcription to replication switch. Nucleic Acids Res. 2025 Jan 24;53(3):gkaf027. Abstract
submitted by kickingbird at Jan, 30, 2025 from Nucleic Acids Res. 2025 Jan 24;53(3):gkaf027 (via https://academic.oup.com/nar/article/53/3/gkaf027/7986046)
The heterotrimeric RNA-dependent RNA polymerase (RdRp) of influenza A virus catalyzes viral RNA transcription (vRNA→mRNA) and replication (vRNA→cRNA→vRNA) by adopting different conformations. A switch ... Jie Hu, Yuting Xu, Min Ma, Chenyao Zhao, Yue Yuan,. Novel Reassortant Avian Influenza A(H9N2) Viruses in Wild Birds in Shanghai, China, 2020–2023. Poultry Science. Abstract
submitted by kickingbird at Jan, 28, 2025 from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
The H9N2 subtype of avian influenza virus poses significant challenges to global poultry and human health. During the active surveillance of avian influenza virus in wild birds in Shanghai from 2020 to ... Yan M, Ma T, Shi X, Chen Q, Li L, Xu B, Pan X, Ten. Isolation and Characterization of H1 Subtype Swine Influenza Viruses Recently Circulating in China. Viruses. 2025; 17(2):185. Abstract
submitted by kickingbird at Jan, 28, 2025 from Viruses. 2025; 17(2):185 (via https://www.mdpi.com/1999-4915/17/2/185)
Pigs serve as a mixing vessel for influenza viruses and can independently promote the emergence of pandemic strains in humans. During our surveillance of pig populations from 2021 to 2023 in China, 11 ... Figueroa T, Bessière P, Coggon A, Bouwman KM, van. The Microbiota Contributes to the Control of Highly Pathogenic H5N9 Influenza Virus Replication in Ducks. J Virol. 2020 May 4;94(10):e00289-20. Abstract
submitted by kickingbird at Jan, 28, 2025 from J Virol. 2020 May 4;94(10):e00289-20 (via https://journals.asm.org/doi/10.1128/jvi.00289-20)
Ducks usually show little or no clinical signs following highly pathogenic avian influenza virus infection. In order to analyze whether the microbiota could contribute to the control of influenza virus ... Yuk SS, To EO, Kwon JH, Noh JY, Hong WT, Jeong JH,. Optimization of inactivated H5N9 highly pathogenic avian influenza vaccine and inactivated Salmonella enterica serovar Typhimurium vaccine with antigen dose and prime-boost regimen in domestic ducks. Poult Sci. 2017 Sep 1;96(9):3079-3085. Abstract
submitted by kickingbird at Jan, 28, 2025 from Poult Sci. 2017 Sep 1;96(9):3079-3085 (via https://www.sciencedirect.com/science/article/pii/S003257911)
Owing to the increase in the number of diseases affecting ducks and the demand for food safety by consumers, vaccination has become one of the factors that influence duck meat productivity. The highly ... Smith S, Rayner JO, Kim JH. Fluorofurimazine, a novel NanoLuc substrate, enhances real-time tracking of influenza A virus infection without altering pathogenicity in mice. Microbiol Spectr. 2025 Jan 27:e0268924. Abstract
submitted by kickingbird at Jan, 28, 2025 from Microbiol Spectr. 2025 Jan 27:e0268924 (via https://journals.asm.org/doi/10.1128/spectrum.02689-24)
Bioluminescence imaging (BLI) using engineered bioluminescent viruses has emerged as a powerful tool for real-time, noninvasive monitoring of viral replication in living animals. While traditional luciferase-based ... Gu J, Yan Y, Zeng Z, Liu D, Hu J, Hu S, Wang X, Gu. Hemagglutinin with a polybasic cleavage site confers high virulence on H7N9 avian influenza viruses. Poult Sci. 2025 Jan 18;104(2):104832. Abstract
submitted by kickingbird at Jan, 27, 2025 from Poult Sci. 2025 Jan 18;104(2):104832 (via https://www.sciencedirect.com/science/article/pii/S003257912)
H7N9 avian influenza virus (AIV) first emerged in February 2013 in China, and early isolates were all low pathogenic (LP). After circulation for a few years in live poultry markets of China, LP H7N9 AIVs ... Katharina Daniel, etc.,al. [preprint]Detection of low pre-existing humoral immunity against influenza virus H5N1 clade 2.3.4.4b in unexposed individuals. https://doi.org/10.1101/2025.01.22.634277. Abstract
submitted by kickingbird at Jan, 26, 2025 from https://doi.org/10.1101/2025.01.22.634277 (via https://www.biorxiv.org/content/10.1101/2025.01.22.634277v1)
The repeated spill-over of Influenza A virus H5N1 clade 2.3.4.4b from cattle to humans highlights the risk of a human H5N1 pandemic. Given the impact of pre-existing immunity on the course and severity ... Caliendo V, Bellido Martin B, Fouchier RAM, Verdaa. Highly Pathogenic Avian Influenza Contributes to the Population Decline of the Peregrine Falcon (Falco peregrinus) in The Netherlands. Viruses. 2024 Dec 27;17(1):24. Abstract
submitted by kickingbird at Jan, 26, 2025 from Viruses. 2024 Dec 27;17(1):24 (via https://www.mdpi.com/1999-4915/17/1/24)
Highly pathogenic avian influenza (HPAI) epizootics have caused repeated mass mortality events among wild birds. The effect of the infection is potentially detrimental for a variety of bird species, including ... Alvarez I, Banihashem F, Persson A, Hurri E, Kim H. Detection and Phylogenetic Characterization of Influenza D in Swedish Cattle. Viruses. 2024 Dec 26;17(1):17. Abstract
submitted by kickingbird at Jan, 26, 2025 from Viruses. 2024 Dec 26;17(1):17 (via https://www.mdpi.com/1999-4915/17/1/17)
Increased evidence suggests that cattle are the primary host of Influenza D virus (IDV) and may contribute to respiratory disease in this species. The aim of this study was to detect and characterise IDV ... Sheikh, M.O.B., Rashid, P.M.A., Rahim, Z.H. et al. Molecular characterization and genetic analysis of highly pathogenic H5N1 clade 2.3.4.4b in seagulls from Dukan Lake, Iraq. Virus Genes (2025). Abstract
submitted by kickingbird at Jan, 24, 2025 from Virus Genes (2025) (via https://link.springer.com/article/10.1007/s11262-025-02133-7)
Avian influenza virus (AIV) remains a significant global threat, with periodic reemergence in Iraq. This study marks the first molecular characterization of the highly pathogenic avian influenza (HPAI) ... Good MR, Suja D, Guthmiller JJ. The sweet side of H5N1 influenza virus infection. PLoS Pathog 21(1): e1012847. Abstract
submitted by kickingbird at Jan, 24, 2025 from PLoS Pathog 21(1): e1012847 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
H5Nx viruses remain a threat to human health. Over the past few years, the H5Nx clade 2.3.4.4b has rapidly spread to 6 continents, leading to massive avian and mammalian host deaths. In late March 2024, ... Zhang M, Zeng Z, Chen X, Wang G, Cai X, Hu Z, Gu M. Phosphorylation of PA at serine 225 enhances viral fitness of the highly pathogenic H5N1 avian influenza virus in mice. Vet Microbiol. 2025 Jan 20;302:110400. Abstract
submitted by kickingbird at Jan, 24, 2025 from Vet Microbiol. 2025 Jan 20;302:110400 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Currently, there is increasing spillover of highly pathogenic H5N1 avian influenza virus (AIV) to mammals, raising a concern of pandemic threat about this virus. Although the function of PA protein of ... 6502 items, 20/Page, Page[40/326][|<<] [|<] [31] [32] [33] [34] [35] [36] [37] [38] [39] [40] [>|] [>>|] |
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