Louie AY, Kim JS, Drnevich J, Dibaeinia P, Koito H. Influenza A virus infection disrupts oligodendrocyte homeostasis and alters the myelin lipidome in the adult mouse. J Neuroinflammation. 2023 Aug 19;20(1):190. Abstract
submitted by kickingbird at Aug, 21, 2023 from J Neuroinflammation. 2023 Aug 19;20(1):190 (via https://jneuroinflammation.biomedcentral.com/articles/10.118)
Background: Recent data suggest that myelin may be altered by physiological events occurring outside of the central nervous system, which may cause changes to cognition and behavior. Similarly, peripheral ... Alalem M, Dabous E, Awad AM, Alalem N, Guirgis AA,. Influenza a virus regulates interferon signaling and its associated genes; MxA and STAT3 by cellular miR-141 to ensure viral replication. Virol J. 2023 Aug 18;20(1):183. Abstract
submitted by kickingbird at Aug, 21, 2023 from Virol J. 2023 Aug 18;20(1):183 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
The antiviral response against influenza A virus (IAV) infection includes the induction of the interferon (IFN) signaling pathway, including activation of the STATs protein family. Subsequently, antiviral ... El-Shall NA, Abd El Naby WSH, Hussein EGS, Yonis A. Pathogenicity of H5N8 avian influenza virus in chickens and in duck breeds and the role of MX1 and IFN-α in infection outcome and transmission to contact birds. Comp Immunol Microbiol Infect Dis. 2023 Aug 3;100:. Abstract
submitted by kickingbird at Aug, 21, 2023 from Comp Immunol Microbiol Infect Dis. 2023 Aug 3;100: (via https://www.sciencedirect.com/science/article/abs/pii/S01479)
This study examined the pathogenicity, immunogenicity, and transmission potential of the H5N8 HPAI clade 2.3.4.4b virus in three breeds of ducks and in broiler chickens. Chickens, Muscovy, Pekin, and Mallard ... Bergant V, Schnepf D, de Andrade Kr?tzig N, Hubel. mRNA 3´UTR lengthening by alternative polyadenylation attenuates inflammatory responses and correlates with virulence of Influenza A virus. Nat Commun. 2023 Aug 15;14(1):4906. Abstract
submitted by kickingbird at Aug, 17, 2023 from Nat Commun. 2023 Aug 15;14(1):4906 (via https://www.nature.com/articles/s41467-023-40469-6)
Changes of mRNA 3'UTRs by alternative polyadenylation (APA) have been associated to numerous pathologies, but the mechanisms and consequences often remain enigmatic. By combining transcriptomics, proteomics ... Wang X, Liu K, Guo Y, Pei Y, Chen X, Lu X, Gao R,. Emergence of a new designated clade 16 with significant antigenic drift in hemagglutinin gene of H9N2 subtype avian influenza virus in eastern China. Emerg Microbes Infect. 2023 Aug 16:2249558. Abstract
submitted by kickingbird at Aug, 17, 2023 from Emerg Microbes Infect. 2023 Aug 16:2249558 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2)
H9N2 avian influenza viruses (AIVs) pose an increasing threat to the poultry industry worldwide and have pandemic potential. Vaccination has been principal prevention strategy to control H9N2 in China ... Huang X, Cai Y, Yin G, Chen Z, Hu J, Gao Z, Guo X,. Identification of catalytically active domain epitopes in neuraminidase protein of H9N2 subtype of avian influenza virus. Avian Pathol. 2023 Aug 15:1-11. Abstract
submitted by kickingbird at Aug, 16, 2023 from Avian Pathol. 2023 Aug 15:1-11 (via https://www.tandfonline.com/doi/abs/10.1080/03079457.2023.22)
H9N2 subtype of avian influenza virus (AIV) is primarily a bird virus, which is widespread in clinical avian disease, and reported in cases of human infection. As one of the surface proteins of AIV, the ... Xia J, Li YX, Dong MY, Guo ZW, Luo YW, Li NL, Zhao. Evolution of prevalent H9N2 subtype of avian influenza virus during 2019 to 2022 for the development of a control strategy in China. Poult Sci. 2023 Jul 25;102(10):102957. Abstract
submitted by kickingbird at Aug, 16, 2023 from Poult Sci. 2023 Jul 25;102(10):102957 (via https://www.sciencedirect.com/science/article/pii/S003257912)
The H9N2 subtype of avian influenza virus (H9N2 AIV) has caused significant losses in chicken flocks throughout China. At present, consensus has been reached that field isolates of H9N2 underwent antigenic ... Kok A, Scheuer R, Bestebroer TM, Burke DF, Wilks S. Characterization of A/H7 influenza virus global antigenic diversity and key determinants in the hemagglutinin globular head mediating A/H7N9 antigenic evolution. mBio. 2023 Aug 11:e0048823. Abstract
submitted by kickingbird at Aug, 12, 2023 from mBio. 2023 Aug 11:e0048823 (via https://journals.asm.org/doi/10.1128/mbio.00488-23)
Avian A/H7 influenza viruses are a global threat to animal and human health. These viruses continue to cause outbreaks in poultry and have caused the highest number of reported zoonotic infections to date, ... Thomas SN, Niemeyer BF, Jimenez-Valdes RJ, Kaiser. Down syndrome is associated with altered frequency and functioning of tracheal multiciliated cells, and response to influenza virus infection. iScience. 2023 Jul 14;26(8):107361. Abstract
submitted by kickingbird at Aug, 10, 2023 from iScience. 2023 Jul 14;26(8):107361 (via https://www.cell.com/iscience/fulltext/S2589-0042(23)01438-4)
Individuals with Down syndrome (DS) clinically manifest severe respiratory illnesses; however, there is a paucity of data on how DS influences homeostatic physiology of lung airway, and its reactive responses ... Tonouchi K, Adachi Y, Suzuki T, Kuroda D, Nishiyam. Structural basis for cross-group recognition of an influenza virus hemagglutinin antibody that targets postfusion stabilized epitope. PLoS Pathog. 2023 Aug 9;19(8):e1011554. Abstract
submitted by kickingbird at Aug, 10, 2023 from PLoS Pathog. 2023 Aug 9;19(8):e1011554 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Plasticity of influenza virus hemagglutinin (HA) conformation increases an opportunity to generate conserved non-native epitopes with unknown functionality. Here, we have performed an in-depth analysis ... Xie Q, Liao X, Huang B, Wang L, Liao G, Luo C, Wen. The truncated IFITM3 facilitates the humoral immune response in inactivated influenza vaccine-vaccinated mice via interaction with CD81. Emerg Microbes Infect. 2023 Aug 9:2246599. Abstract
submitted by kickingbird at Aug, 10, 2023 from Emerg Microbes Infect. 2023 Aug 9:2246599 (via https://pubmed.ncbi.nlm.nih.gov/37556756/)
A single-nucleotide polymorphism (SNP) rs12252-C of interferon-induced transmembrane protein 3 (IFITM3), resulting in a truncated IFITM3 protein lacking 21 N-terminus amino acids, is associated with severe ... Zeller MA, Ma J, Wong FY, Tum S, Hidano A, Holt H,. The genomic landscape of swine influenza A viruses in Southeast Asia. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e230. Abstract
submitted by kickingbird at Aug, 9, 2023 from Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e230 (via https://www.pnas.org/doi/10.1073/pnas.2301926120)
Swine are a primary source for the emergence of pandemic influenza A viruses. The intensification of swine production, along with global trade, has amplified the transmission and zoonotic risk of swine ... Tsang TK, Wang C, Fang VJ, Perera RAPM, So HC, Ip. Reconstructing household transmission dynamics to estimate the infectiousness of asymptomatic influenza virus infections. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e230. Abstract
submitted by kickingbird at Aug, 8, 2023 from Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e230 (via https://www.pnas.org/doi/10.1073/pnas.2304750120)
There has long been controversy over the potential for asymptomatic cases of the influenza virus to have the capacity for onward transmission, but recognition of asymptomatic transmission of COVID-19 stimulates ... Yang Y, Huang Y, Huang K, Zhang Y, Hu X, Zou W, Wu. Isolation and identification of Eurasian avian-like H1N1 swine influenza virus and evaluation of their pathogenicity and immune protective effects in pigs. Vet Microbiol. 2023 Jul 12;284:109827. Abstract
submitted by kickingbird at Aug, 7, 2023 from Vet Microbiol. 2023 Jul 12;284:109827 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Swine influenza (SI) is a severe disease affecting pigs, with a huge economic impact on pig farmers. Currently, available SIV vaccines do not meet the requirements for Swine influenza prevention and control, ... Xu S, Yu L, Teng Q, Li X, Jin Z, Qu Y, Li J, Zhang. Enhance immune response to H9 AIV DNA vaccine based on polygene expression and DGL nanoparticle encapsulation. Poult Sci. 2023 Jul 6;102(10):102925. Abstract
submitted by kickingbird at Aug, 7, 2023 from Poult Sci. 2023 Jul 6;102(10):102925 (via https://www.sciencedirect.com/science/article/pii/S003257912)
DNA vaccination has great potential to treat or prevent avian influenza pandemics, but the technique may be limited by low immunogenicity and gene delivery in clinical testing. Here, to improve the immune ... Thompson D, Cismaru CV, Rougier JS, Schwemmle M, Z. The M2 proteins of bat influenza A viruses reveal atypical features compared to conventional M2 proteins. J Virol. 2023 Aug 4:e0038823. Abstract
submitted by kickingbird at Aug, 5, 2023 from J Virol. 2023 Aug 4:e0038823 (via https://journals.asm.org/doi/10.1128/jvi.00388-23)
The influenza A virus (IAV) M2 protein has proton channel activity, which plays a role in virus uncoating and may help to preserve the metastable conformation of the IAV hemagglutinin (HA). In contrast ... Farrell A, Phan T, Brooke CB, Koelle K, Ke R. Semi-infectious particles contribute substantially to influenza virus within-host dynamics when infection is dominated by spatial structure. Virus Evol. 2023 Mar 21;9(1):vead020. Abstract
submitted by kickingbird at Aug, 5, 2023 from Virus Evol. 2023 Mar 21;9(1):vead020 (via https://academic.oup.com/ve/article/9/1/vead020/7117732)
Influenza is an ribonucleic acid virus with a genome that comprises eight segments. Experiments show that the vast majority of virions fail to express one or more gene segments and thus cannot cause a ... Moreno G, Carbonell R, Díaz E, Martín-Loeches I, R. Effectiveness of prolonged versus standard-course of oseltamivir in critically ill patients with severe influenza infection: A multicentre cohort study. J Med Virol. 2023 Aug;95(8):e29010. Abstract
submitted by kickingbird at Aug, 5, 2023 from J Med Virol. 2023 Aug;95(8):e29010 (via https://onlinelibrary.wiley.com/doi/10.1002/jmv.29010)
The aim of this study is to investigate the effectiveness of prolonged versus standard course oseltamivir treatment among critically ill patients with severe influenza. A retrospective study of a prospectively ... Mo J, Spackman E, Swayne DE. Prediction of highly pathogenic avian influenza vaccine efficacy in chickens by comparison of in vitro and in vivo data: A meta-analysis and systematic review. Vaccine. 2023 Aug 1:S0264-410X(23)00922-2. Abstract
submitted by kickingbird at Aug, 4, 2023 from Vaccine. 2023 Aug 1:S0264-410X(23)00922-2 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Vaccines for avian influenza (AI) can protect poultry against disease, mortality, and virus transmission. Numerous factors, including: vaccine platform, immunogenicity, and relatedness to the field strain, ... Zhou H, Liu J, Li L, Sun J, Wei Q, Huan Y, Carr MJ. Circulation of influenza C virus of C/Sao Paulo/378/82 lineage among pediatric acute respiratory cases, Shandong, China. Virology. 2023 Jul 27;587:109855. Abstract
submitted by kickingbird at Aug, 4, 2023 from Virology. 2023 Jul 27;587:109855 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Influenza C virus (ICV) was identified in five pediatric acute respiratory cases in Shandong. Co-infection with other respiratory viruses was detected in four of these cases. Two ICV genomes were obtained ... 5581 items, 20/Page, Page[36/280][|<<] [|<] [31] [32] [33] [34] [35] [36] [37] [38] [39] [40] [>|] [>>|] |
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