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2024-4-20 0:38:32
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SONG D, Moon H, An DJ, Jeong HY, et al.. A Novel Reassortant Canine H3N1 Influenza Virus between Pandemic H1N1 and Canine H3N2 Influenza Viruses in Korea. J Gen Virol. 2011.  Abstract  
submitted by kickingbird at Dec, 20, 2011 from J Gen Virol. 2011 (via http://www.ncbi.nlm.nih.gov/pubmed/22131311)
During recent canine influenza surveillance in South Korea, a novel canine influenza virus (CIV) H3N1 which was a putative reassortant between pandemic H1N1 2009 and H3N2 canine influenza viruses was isolated. ...

Nobuhiro Takemae, Sujira Parchariyanon, Ruttapong. Swine influenza virus infection in different age groups of pigs in farrow-to-finish farms in Thailand. Virology Journal 2011, 8:537.  Abstract  
submitted by kickingbird at Dec, 15, 2011 from Virology Journal 2011, 8:537 (via http://www.virologyj.com/content/8/1/537/abstract)
Background Understanding swine influenza virus (SIV) ecology has become more and more important from both the pig industry and public health points of views. However, the mechanism whereby SIV occurs ...

Epstein S. T-Cell Immune Responses and Asymptomatic H5N1 Influenza Infection. J Infect Dis 2011.  Abstract  
submitted by kickingbird at Dec, 3, 2011 from J Infect Dis 2011 (via http://jid.oxfordjournals.org/content/early/2011/11/10/infdi)
Approximately 60% of people ill with influenza A virus subtype H5N1 infection die [1], a case fatality rate about 25 times worse than that during the 1918 pandemic [2]. It is hard to even imagine the devastation ...

Powell TJ, Fox A, Peng Y, et al.. Identification of H5N1-Specific T-Cell Responses in a High-risk Cohort in Vietnam Indicates the Existence of Potential Asymptomatic Infections. J Infect Dis 2011.  Abstract  
submitted by kickingbird at Dec, 3, 2011 from J Infect Dis 2011 (via http://jid.oxfordjournals.org/content/early/2011/11/10/infdi)
Background.?Most reported human H5N1 viral infections have been severe and were detected after hospital admission. A case ascertainment bias may therefore exist, with mild cases or asymptomatic infections ...

Ma W, Lager KM, Li X, Janke BH, Mosier DA, Painter. Pathogenicity of swine influenza viruses possessing an avian or swine-origin PB2 polymerase gene evaluated in mouse and pig models. Virology. 2011 Feb 5;410(1):1-6. Epub 2010 Nov 11..  Abstract  
submitted by kickingbird at Nov, 28, 2011 from Virology. 2011 Feb 5;410(1):1-6. Epub 2010 Nov 11. (via http://www.ncbi.nlm.nih.gov/pubmed/21074235)
PB2 627K is a determinant of influenza host range and contributes to the pathogenicity of human-, avian-, and mouse-adapted influenza viruses in the mouse model. Here we used mouse and pig models to analyze ...

Song MS, Pascua PN, Lee JH, Baek YH, Park KJ, Kwon. Virulence and genetic compatibility of polymerase reassortant viruses derived from the pandemic (H1N1) 2009 influenza virus and circulating influenza A viruses.. J Virol. 2011 Jul;85(13):6275-86. Epub 2011 Apr 20.  Abstract  
submitted by kickingbird at Nov, 28, 2011 from J Virol. 2011 Jul;85(13):6275-86. Epub 2011 Apr 20 (via http://www.ncbi.nlm.nih.gov/pubmed/21507962)
Gene mutations and reassortment are key mechanisms by which influenza A virus acquires virulence factors. To evaluate the role of the viral polymerase replication machinery in producing virulent pandemic ...

Schrauwen EJ, Herfst S, Chutinimitkul S, Bestebroe. Possible increased pathogenicity of pandemic (H1N1) 2009 influenza virus upon reassortment. Emerg Infect Dis. 2011 Feb;17(2):200-8..  Abstract  
submitted by kickingbird at Nov, 28, 2011 from Emerg Infect Dis. 2011 Feb;17(2):200-8. (via http://www.ncbi.nlm.nih.gov/pubmed/21291589)
Since emergence of the pandemic (H1N1) 2009 virus in April 2009, three influenza A viruses-seasonal (H3N2), seasonal (H1N1), and pandemic (H1N1) 2009-have circulated in humans. Genetic reassortment between ...

Calistri A, Salata C, Cosentino M, etc., al. Report of two cases of influenza virus A/H1N1v and B coinfection during the 2010/2011 epidemics in the Italian Veneto region. Virol J 2011 Nov 3;8(502).  Abstract  
submitted by kickingbird at Nov, 6, 2011 from Virol J 2011 Nov 3;8(502) (via http://www.virologyj.com/content/8/1/502/abstract)
From October 2010 to April 2011, in the Italian Veneto Region, 1403 hospitalized patients were tested for influenza virus infection by specific real time RT-PCR. Overall, 327 samples were positive for ...

Myers CA, Kasper MR, Yasuda CY, etc., al. Dual infection of novel influenza A/H3N2 in a cluster of Cambodian patients. Am J Trop Med Hyg 2011 Nov;85(5):961-3.  Abstract  
submitted by kickingbird at Nov, 6, 2011 from Am J Trop Med Hyg 2011 Nov;85(5):961-3 (via http://www.ajtmh.org/content/85/5/961.abstract?sid=8e64400d-)
During the early months of 2009, a novel influenza A/H1N1 virus (pH1N1) emerged in Mexico and quickly spread across the globe. In October 2009, a 23-year-old male residing in central Cambodia was diagnosed ...

Tsukamoto K, Javier PC, Shishido M, Noguchi D, Pea. SYBR Green Based Real-Time Reverse Transcription PCR for Typing and Subtyping of All Hemagglutinin and Neuraminidase genes of Avian Influenza Viruses and Comparison to Standard Serological Subtyping. J Clin Microbiol. 2011 Oct 26..  Abstract  
submitted by kickingbird at Oct, 30, 2011 from J Clin Microbiol. 2011 Oct 26. (via http://www.ncbi.nlm.nih.gov/pubmed/22031706)
Continuing outbreaks of H5N1 highly pathogenic (HP) avian influenza virus (AIV) infections of wild birds and poultry worldwide emphasize the need for global surveillance of wild birds. To support the future ...

Morimoto J, Sato K, Nakayama Y, Kimura C, Kajino K. Osteopontin Modulates the Generation of Memory CD8+ T Cells during Influenza Virus Infection. J Immunol. 2011 Oct 21.  Abstract  
submitted by kickingbird at Oct, 30, 2011 from J Immunol. 2011 Oct 21 (via http://www.ncbi.nlm.nih.gov/pubmed/22021613)
The adaptive immune system generates memory cells, which induce a rapid and robust immune response following secondary Ag encounter. Memory CD8(+) T cells are a critical component of protective immunity ...

Shinya K, Ito M, Makino A, Tanaka M, Miyake K, Eis. The TLR4-TRIF pathway protects against H5N1 influenza virus infection.. J Virol. 2011 Oct 26..  Abstract  
submitted by kickingbird at Oct, 30, 2011 from J Virol. 2011 Oct 26. (via http://www.ncbi.nlm.nih.gov/pubmed/22031950)
Pre-stimulation of the TLR4 pathway with lipopolysaccharide (LPS) protects mice from lethal infection with H5N1 influenza virus. Here, we reveal that the TLR4-TRIF pathway is required for this protective ...

García-Sastre A.. Induction and evasion of type I interferon responses by influenza viruses.. Virus Res. 2011 Oct 21..  Abstract  
submitted by kickingbird at Oct, 30, 2011 from Virus Res. 2011 Oct 21. (via http://www.ncbi.nlm.nih.gov/pubmed/22027189)
Influenza A and B viruses are a major cause of respiratory disease in humans. In addition, influenza A viruses continuously re-emerge from animal reservoirs into humans causing human pandemics every 10-50 ...

Pan D, Sun H, Shen Y, Liu H, Yao X.. Exploring the molecular basis of dsRNA recognition by NS1 protein of influenza A virus using molecular dynamics simulation and free energy calculation. Antiviral Res. 2011 Oct 4..  Abstract  
submitted by kickingbird at Oct, 30, 2011 from Antiviral Res. 2011 Oct 4. (via http://www.ncbi.nlm.nih.gov/pubmed/22001595)
The frequent outbreak of influenza pandemic and the limited available anti-influenza drugs highlight the urgent need for the development of new antiviral drugs. The dsRNA-binding surface of nonstructural ...

Suzuki T, Ainai A, Nagata N, Sata T, Sawa H, Haseg. A novel function of the N-terminal domain of PA in assembly of influenza A virus RNA polymerase. Biochem Biophys Res Commun. 2011 Oct 6..  Abstract  
submitted by kickingbird at Oct, 30, 2011 from Biochem Biophys Res Commun. 2011 Oct 6. (via http://www.ncbi.nlm.nih.gov/pubmed/22001919)
Transcription and replication of the negative-sense single-stranded influenza A virus genomic viral RNA are catalyzed by the viral RNA polymerase, which is a trimeric complex encoded by the three largest ...

Tremblay D, Allard V, Doyon JF, Bellehumeur C, Spe. Emergence of a new swine H3N2 and pandemic (H1N1) 2009 influenza A virus reassortant in two Canadian animal populations, mink and swine. J Clin Microbiol. 2011 Oct 19..  Abstract  
submitted by kickingbird at Oct, 30, 2011 from J Clin Microbiol. 2011 Oct 19. (via http://www.ncbi.nlm.nih.gov/pubmed/22012020)
A swine H3N2 (swH3N2) and pandemic (H1N1) 2009 (pH1N1) influenza A virus reassortant (swH3N2/pH1N1) was detected in Canadian swine at the end of 2010. Simultaneously, a similar virus was also detected ...

Thaa B, Tielesch C, Moller L, Schmitt AO, Wolff T,. Growth of influenza A virus is not impeded by simultaneous removal of the cholesterol binding and acylation sites in the M2 protein. J Gen Virol. 2011 Oct 19.  Abstract  
submitted by kickingbird at Oct, 30, 2011 from J Gen Virol. 2011 Oct 19 (via http://www.ncbi.nlm.nih.gov/pubmed/22012459)
Influenza virus assembly and budding occur in the 'budozone', a coalesced raft domain in the plasma membrane. The viral transmembrane protein M2 is implicated in virus particle scission, the ultimate step ...

Hui KP, Lee SM, Cheung CY, Mao H, Lai AK, Chan RW,. H5N1 Influenza Virus-Induced Mediators Upregulate RIG-I in Uninfected Cells by Paracrine Effects Contributing to Amplified Cytokine Cascades. J Infect Dis. 2011 Oct.  Abstract  
submitted by kickingbird at Oct, 30, 2011 from J Infect Dis. 2011 Oct (via http://www.ncbi.nlm.nih.gov/pubmed/22013225)
Highly pathogenic avian influenza H5N1 viruses cause severe disease in humans, and dysregulation of cytokine responses is believed to contribute to the pathogenesis of human H5N1 disease. However, mechanisms ...

Ohmit SE, Petrie JG, Cross RT, Johnson E, Monto AS. Influenza Hemagglutination-Inhibition Antibody Titer as a Correlate of Vaccine-Induced Protection. J Infect Dis. 2011 Oct 12..  Abstract  
submitted by kickingbird at Oct, 30, 2011 from J Infect Dis. 2011 Oct 12. (via http://www.ncbi.nlm.nih.gov/pubmed/21998477)
Background.?Antibody to influenza virus hemagglutinin has been traditionally associated with protection. Questions have been raised about its use as a surrogate for vaccine efficacy, particularly with ...

Ginting TE, Shinya K, Kyan Y, Makino A, Matsumoto. Amino acid changes in hemagglutinin contribute to the replication of oseltamivir-resistant H1N1 influenza viruses. J Virol. 2011 Oct 19.  Abstract  
submitted by kickingbird at Oct, 30, 2011 from J Virol. 2011 Oct 19 (via http://www.ncbi.nlm.nih.gov/pubmed/22013054)
Oseltamivir-resistant H1N1 influenza viruses emerged in 2007-2008 and have subsequently circulated widely. However, prior to 2007-2008, viruses possessing the neuraminidase (NA) H274Y mutation, which confers ...

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