Chen G-W, Kuo S-M, Yang S-L, Gong Y-N, Hsiao M-R,. Genomic Signatures for Avian H7N9 Viruses Adapting to Humans. PLoS ONE 11(2): e0148432.. Abstract
submitted by kickingbird at Feb, 11, 2016 from PLoS ONE 11(2): e0148432. (via http://journals.plos.org/plosone/article?id=10.1371/journal.)
An avian influenza A H7N9 virus emerged in March 2013 and caused a remarkable number of human fatalities. Genome variability in these viruses may provide insights into host adaptability. We scanned over ... MEYER L, Sausset A, Sedano L, Da Costa B, et al. Codon deletions in the influenza A virus PA gene generate temperature-sensitive viruses. J Virol. 2016 Jan 20. pii: JVI.03101-15.. Abstract
submitted by kickingbird at Jan, 24, 2016 from J Virol. 2016 Jan 20. pii: JVI.03101-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26792748)
The influenza virus RNA-dependent RNA polymerase which is composed of three subunits, PB1, PB2, and PA, catalyses genome replication and transcription within the cell nucleus. The PA linker (residues 197-256) ... JAIRAK W, Boonyapisitsopa S, Chaiyawong S, Nonthab. Genetic characterization of influenza A (H7N6) virus isolated from a live-bird market in Thailand. Arch Virol. 2016 Jan 21.. Abstract
submitted by kickingbird at Jan, 24, 2016 from Arch Virol. 2016 Jan 21. (via http://www.ncbi.nlm.nih.gov/pubmed/26795160)
A one-year influenza A virus (IAV) monitoring program was conducted in a live-bird market (LBM) in Thailand. Using one-step real-time RT-PCR (rRT-PCR), 2.39 % of live birds were found to be IAV positive. ... WANG J, Wu M, Hong W, Fan X, et al. Infectivity and Transmissibility of Avian H9N2 Influenza Viruses in Pigs. J Virol. 2016 Jan 13. pii: JVI.02605-15.. Abstract
submitted by kickingbird at Jan, 17, 2016 from J Virol. 2016 Jan 13. pii: JVI.02605-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26764002)
The H9N2 influenza viruses that are enzootic in terrestrial poultry in China pose a persistent pandemic threat to humans. To investigate whether the continuous circulation and adaptation of these viruses ... CHEN CJ, Ermler ME, Tan GS, Krammer F, et al. Influenza A viruses expressing intra- or inter-group chimeric hemagglutinins. J Virol. 2016 Jan 13. pii: JVI.03060-15. Abstract
submitted by kickingbird at Jan, 17, 2016 from J Virol. 2016 Jan 13. pii: JVI.03060-15 (via http://www.ncbi.nlm.nih.gov/pubmed/26764009)
A panel of influenza A viruses expressing chimeric hemagglutinins (cHA) with intragroup or intergroup head/stalk combinations was generated. Viruses were characterized for growth kinetics and preservation ... GAGLANI M, Pruszynski J, Murthy K, Clipper L, et a. Influenza Vaccine Effectiveness Against 2009 Pandemic Influenza A(H1N1) Virus Differed by Vaccine Type During 2013-2014 in the United States. J Infect Dis. 2016 Jan 6. pii: jiv577. Abstract
submitted by kickingbird at Jan, 17, 2016 from J Infect Dis. 2016 Jan 6. pii: jiv577 (via http://www.ncbi.nlm.nih.gov/pubmed/26743842)
BACKGROUND:
?The predominant strain during the 2013-2014 influenza season was 2009 pandemic influenza A(H1N1) virus (A[H1N1]pdm09). This vaccine-component has remained unchanged from 2009.
METHODS: ... WU C, Wang MH, Lu X, Chong M, et al. Concurrent epidemics of influenza A/H3N2 and A/H1N1pdm in Southern China: A serial cross-sectional study. J Infect. 2015 Dec 30. pii: S0163-4453(15)00405-3.. Abstract
submitted by kickingbird at Jan, 17, 2016 from J Infect. 2015 Dec 30. pii: S0163-4453(15)00405-3. (via http://www.ncbi.nlm.nih.gov/pubmed/26747013)
OBJECTIVES:
This study aimed to elucidate the antibody response pattern of multiple influenza subtypes through a 4-year serological study of a general population in Shenzhen, Southern China.
METHODS: ... MOSTAFA A, Kanrai P, Ziebuhr J, Pleschka S, et al. The PB1 segment of an influenza A virus H1N1 2009pdm isolate enhances the replication efficiency of specific influenza vaccine strains in cell culture and embryonated eggs. J Gen Virol. 2016 Jan 7. doi: 10.1099/jgv.0.000390. Abstract
submitted by kickingbird at Jan, 17, 2016 from J Gen Virol. 2016 Jan 7. doi: 10.1099/jgv.0.000390 (via http://www.ncbi.nlm.nih.gov/pubmed/26743314)
Influenza vaccine strains (IVS) contain the hemagglutinin (HA) and neuraminidase (NA) genome segments of relevant circulating strains in the genetic background of influenza A/PR/8/1934 virus (PR8). Previous ... CHEN LJ, Lin XD, Guo WP, Tian JH, et al. Diversity and evolution of avian influenza viruses in live poultry markets, free range poultry and wild wetland birds in China. J Gen Virol. 2016 Jan 12. doi: 10.1099/. Abstract
submitted by kickingbird at Jan, 17, 2016 from J Gen Virol. 2016 Jan 12. doi: 10.1099/ (via http://www.ncbi.nlm.nih.gov/pubmed/26758561)
The wide circulation of novel avian influenza viruses (AIVs) highlights the risk of pandemic influenza emergence in China. To investigate the prevalence and genetic diversity of AIVs in different ecological ... ZHANG J, Zhang Z, Fan HY, Zhang J, et al. Recombinant baculovirus vaccine containing multiple M2e and adjuvant LTB induces T cell dependent, cross-clade protection against H5N1 influenza virus in mice. Vaccine. 2015 Dec 23. Abstract
submitted by kickingbird at Jan, 10, 2016 from Vaccine. 2015 Dec 23 (via http://www.amedeo.com/p2.php?id=26724200&s=flu&pm=6213b1b427)
H5N1, highly pathogenic avian influenza poses, a threat to animal and human health. Rapid changes in H5N1 viruses require periodic reformulation of the conventional strain-matched vaccines, thus emphasizing ... THARAKARAMAN K, Subramanian V, Viswanathan K, Sloa. A broadly neutralizing human monoclonal antibody is effective against H7N9. Proc Natl Acad Sci U S A. 2015 Sep 1;. Abstract
submitted by kickingbird at Jan, 10, 2016 from Proc Natl Acad Sci U S A. 2015 Sep 1; (via http://www.ncbi.nlm.nih.gov/pubmed/26283346)
Emerging strains of influenza represent a significant public health threat with potential pandemic consequences. Of particular concern are the recently emerged H7N9 strains which cause pneumonia with acute ... DINIS JM, Florek NW, Fatola OO, Moncla LH, et al. Deep sequencing reveals potential antigenic variants at low frequency in influenza A-infected humans. J Virol. 2016 Jan 6.. Abstract
submitted by kickingbird at Jan, 10, 2016 from J Virol. 2016 Jan 6. (via http://www.ncbi.nlm.nih.gov/pubmed/26739054)
Influenza vaccines must be frequently reformulated to account for antigenic changes in the viral envelope protein, hemagglutinin (HA). The rapid evolution of influenza virus under immune pressure is likely ... CHEN D, Wen X, Sun Y, Mao H, et al. Multiple viral introductions: molecular characterization of influenza B virus in Wenzhou, Zhejiang, China, from 2011 to 2014 based on hemagglutinin and neuraminidase genes. Arch Virol. 2016 Jan 2.. Abstract
submitted by kickingbird at Jan, 10, 2016 from Arch Virol. 2016 Jan 2. (via http://www.ncbi.nlm.nih.gov/pubmed/26724821)
Influenza B virus is a major causative agent of respiratory disease in humans. Our study of an outbreak of influenza B virus in Wenzhou from 2011 to 2014 revealed that 163 (5.58 %) of 2921 samples ... WEI YR, Yang XY, Li YG, Wei J, et al. Serological survey of avian influenza virus infection in non-avian wildlife in Xinjiang, China. Arch Virol. 2016 Jan 5. Abstract
submitted by kickingbird at Jan, 10, 2016 from Arch Virol. 2016 Jan 5 (via http://www.ncbi.nlm.nih.gov/pubmed/26733295)
We conducted a serological survey to detect antibodies against avian influenza virus (AIV) in Gazella subgutturosa, Canis lupus, Capreolus pygargus, Sus scrofa, Cervus elaphus, Capra ibex, Ovis ammon, ... LLM Poon, T Song, R Rosenfeld, etc.,al. Quantifying influenza virus diversity and transmission in humans. Nature Genetics (2016)doi:10.1038/ng.3479. Abstract
submitted by kickingbird at Jan, 9, 2016 from Nature Genetics (2016)doi:10.1038/ng.3479 (via http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3479.)
Influenza A virus is characterized by high genetic diversity. However, most of what is known about influenza evolution has come from consensus sequences sampled at the epidemiological scale that only represent ... WANG L, Wu A, Wang YE, Quanquin N, et al. Functional Genomics Reveals Linkers Critical for Influenza Polymerase. J Virol. 2015 Dec 30. pii: JVI.02400. Abstract
submitted by kickingbird at Jan, 3, 2016 from J Virol. 2015 Dec 30. pii: JVI.02400 (via http://www.ncbi.nlm.nih.gov/pubmed/26719244)
Influenza virus mRNA synthesis by the RNA-dependent RNA polymerase involves binding and cleavage of capped cellular mRNA by the PB2 and PA subunits, respectively, and extension of viral mRNA by PB1. However, ... NACHBAGAUER R, Miller MS, Hai R, Ryder AB, et al. Hemagglutinin stalk immunity reduces influenza virus replication and transmission in ferrets. J Virol. 2015 Dec 30. pii: JVI.02481-15.. Abstract
submitted by kickingbird at Jan, 3, 2016 from J Virol. 2015 Dec 30. pii: JVI.02481-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26719251)
We assessed in ferrets whether influenza virus hemagglutinin stalk-based immunity provided protection against aerosol-transmitted H1N1 infection. Immunization of ferrets with a universal influenza virus ... CAROLAN LA, Rockman S, Borg K, Guarnaccia T, et al. Characterisation of the localised immune response in the respiratory tract of ferrets following infection with influenza A and B viruses. J Virol. 2015 Dec 30. pii: JVI.02797-15. Abstract
submitted by kickingbird at Jan, 3, 2016 from J Virol. 2015 Dec 30. pii: JVI.02797-15 (via http://www.ncbi.nlm.nih.gov/pubmed/26719259)
The burden of infection with seasonal influenza viruses is significant. Each year is typically characterised by the dominance of one (sub)type or lineage of influenza A or B virus, respectively. The incidence ... HANSON A, Imai M, Hatta M, McBride R, et al. Identification of Stabilizing Mutations in an H5 HA Influenza Virus Protein. J Virol. 2015 Dec 30. pii: JVI.02790. Abstract
submitted by kickingbird at Jan, 3, 2016 from J Virol. 2015 Dec 30. pii: JVI.02790 (via http://www.ncbi.nlm.nih.gov/pubmed/26719265)
Highly pathogenic avian influenza viruses of the H5N1 subtype continue to circulate in poultry in Asia, Africa, and the Middle East. Recently, outbreaks of novel reassortant H5 viruses have also occurred ... CHIN AW, Yen HL, Krauss S, Webby RJ, et al. Recombinant influenza virus with a pandemic H2N2 polymerase complex has a higher adaptive potential than one with seasonal H2N2 polymerase complex. J Gen Virol. 2015 Dec 24. doi: 10.1099. Abstract
submitted by kickingbird at Jan, 3, 2016 from J Gen Virol. 2015 Dec 24. doi: 10.1099 (via http://www.ncbi.nlm.nih.gov/pubmed/26703222)
The reassortment of influenza viral gene segments plays a key role in the genesis of pandemic strains. All of the last three pandemic viruses contained reassorted polymerase complexes with subunits derived ... 5584 items, 20/Page, Page[188/280][|<<] [|<] [181] [182] [183] [184] [185] [186] [187] [188] [189] [190] [>|] [>>|] |
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