LIN Q, Li T, Chen Y, Lau SY, et al. Structural Basis for the Broad, Antibody-Mediated Neutralization of H5N1 Influenza Virus. J Virol. 2018 Jun 20. Abstract
submitted by kickingbird at Jun, 24, 2018 from J Virol. 2018 Jun 20 (via https://www.ncbi.nlm.nih.gov/pubmed/29925655)
Human infection with highly pathogenic avian influenza A viruses lead to cause severe diseases and fatalities. We previously identified a potent and broad-neutralizing antibody (bnAb), 13D4, against the ... DE VRIES RD, Altenburg AF, Nieuwkoop NJ, de Brui. Induction of Cross-Clade Antibody and T-Cell Responses by an MVA-Based Influenza H5N1 Vaccine in a Randomized Phase I/IIa Clinical Trial. J Infect Dis. 2018 Apr 18. Abstract
submitted by kickingbird at Jun, 24, 2018 from J Infect Dis. 2018 Apr 18 (via https://www.ncbi.nlm.nih.gov/pubmed/29912453)
Background: Highly pathogenic avian influenza viruses continue to circulate in poultry and wild birds and occasionally infect humans, sometimes with fatal outcome. Development of vaccines is a priority ... LA FRAZIA S, Piacentini S, Riccio A, Rossignol J. The second-generation thiazolide haloxanide is a potent inhibitor of avian influenza virus replication. Antiviral Res. 2018 Jun 13. Abstract
submitted by kickingbird at Jun, 24, 2018 from Antiviral Res. 2018 Jun 13 (via https://www.ncbi.nlm.nih.gov/pubmed/29908209)
The emergence of new avian influenza virus (AIV) strains able to infect humans represents a serious threat to global human health. In addition to surveillance and vaccine development, antiviral therapy ... ?wi?toń E, ?mietanka K.. Phylogenetic and molecular analysis of highly pathogenic avian influenza H5N8 and H5N5 viruses detected in Poland in 2016-2017. Transbound Emerg Dis. 2018 Jun 19. Abstract
submitted by kickingbird at Jun, 24, 2018 from Transbound Emerg Dis. 2018 Jun 19 (via https://www.ncbi.nlm.nih.gov/pubmed/29920971)
Sixty-five poultry outbreaks and sixty-eight events in wild birds were reported during the highly pathogenic H5N8/H5N5 avian influenza epidemic in Poland in 2016-2017. The analysis of all gene segment ... Dai X, Li N, Roller RJ.. Peroxiredoxin 1 protein interacts with influenza virus ribonucleoproteins and is required for efficient virus replication. Vaccine. 2018 Jun 16. Abstract
submitted by kickingbird at Jun, 24, 2018 from Vaccine. 2018 Jun 16 (via https://www.ncbi.nlm.nih.gov/pubmed/29921490)
Cellular proteins that support influenza virus infection represent potential therapeutic targets. Cytoplasmic egress intermediates of influenza A/WSN/33 were isolated and shown to be associated with the ... Zhao M, etc.,al. Prolonged evolution of virus-specific memory T cell immunity post severe avian influenza A (H7N9) virus infection. J Virol. 2018 Jun 20. Abstract
submitted by kickingbird at Jun, 24, 2018 from J Virol. 2018 Jun 20 (via https://www.ncbi.nlm.nih.gov/pubmed/29925664)
Since 2013, influenza A/H7N9 has emerged as the commonest avian influenza subtype causing human infection, and is associated with a high fatality risk. However, the characteristics of immune memory in ... Stadlbauer D, etc.,al. Cross-reactive mouse monoclonal antibodies raised against the hemagglutinin of A/Shanghai/1/2013 (H7N9) protect against novel H7 virus isolates in the mouse model. Emerg Microbes Infect. 2018 Jun 20;7(1):110.. Abstract
submitted by kickingbird at Jun, 24, 2018 from Emerg Microbes Infect. 2018 Jun 20;7(1):110. (via https://www.ncbi.nlm.nih.gov/pubmed/29925896)
Influenza viruses remain a major global public health risk. In addition to seasonal influenza viruses, epizootic influenza A H7 subtype viruses of both the Asian and North American lineage are of concern ... Kesinger E, etc.,al. Influenza D virus M2 protein exhibits ion channel activity in Xenopus laevis oocytes. PLoS One. 2018 Jun 21;13(6):. Abstract
submitted by kickingbird at Jun, 24, 2018 from PLoS One. 2018 Jun 21;13(6): (via https://www.ncbi.nlm.nih.gov/pubmed/29927982)
BACKGROUND: A new type of influenza virus, known as type D, has recently been identified in cattle and pigs. Influenza D virus infection in cattle is typically asymptomatic; however, its infection in swine ... Wang J, etc.,al. Host Long Noncoding RNA lncRNA-PAAN Regulates the Replication of Influenza A Virus. Viruses. 2018 Jun 16;10(6).. Abstract
submitted by kickingbird at Jun, 24, 2018 from Viruses. 2018 Jun 16;10(6). (via https://www.ncbi.nlm.nih.gov/pubmed/29914164)
The productive infection of influenza A virus (IAV) depends on host factors. However, the involvement of long non-coding RNAs (lncRNAs) in IAV infection remains largely uninvestigated. In this work, we ... Valkenburg SA, et al. Protection by universal influenza vaccine is mediated by memory CD4 T cells. Vaccine. 2018 Jun 7. Abstract
submitted by kickingbird at Jun, 18, 2018 from Vaccine. 2018 Jun 7 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29887326/)
There is a diverse array of influenza viruses which circulate between different species, reassort and drift over time. Current seasonal influenza vaccines are ineffective in controlling these viruses. ... Patil G, Zhao M, Song K, Hao W, et al. TRIM41-Mediated Ubiquitination of Nucleoprotein Limits Influenza A Virus Infection. J Virol 2018 Jun 13. Abstract
submitted by kickingbird at Jun, 18, 2018 from J Virol 2018 Jun 13 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29899090/)
Influenza A virus (IAV) is a highly transmissible respiratory pathogen and a major cause of morbidity and mortality around the world. Nucleoprotein (NP) is an abundant IAV protein essential for multiple ... Nachbagauer R, Shore D, Yang H, Johnson SK, et al. Broadly-reactive human monoclonal antibodies elicited following pandemic H1N1 influenza virus exposure protect mice from highly pathogenic H5N1 challenge. J Virol 2018 Jun 13. Abstract
submitted by kickingbird at Jun, 18, 2018 from J Virol 2018 Jun 13 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29899095/)
Broadly cross-reactive antibodies that recognize conserved epitopes within the influenza virus hemagglutinin (HA) stalk domain are of particular interest for their potential use as therapeutic and prophylactic ... Ko EJ, Lee Y, Lee YT, Kim YJ, et al. MPL and CpG combination adjuvants promote homologous and heterosubtypic cross protection of inactivated split influenza virus vaccine. Antiviral Res 2018 Jun 6.. Abstract
submitted by kickingbird at Jun, 18, 2018 from Antiviral Res 2018 Jun 6. (via https://www.ncbi.nlm.nih.gov/m/pubmed/29885376/)
Annual vaccination is not effective in conferring cross-protection against antigenically different influenza viruses. Therefore, it is of high priority to improve the cross protective efficacy of influenza ... Wessels U, etc.,al. A dual motif in the hemagglutinin of H5N1 Goose/Guangdong-like HPAIV is conserved from their early evolution and increases both membrane fusion pH and virulence. J Virol. 2018 Jun 13. Abstract
submitted by kickingbird at Jun, 17, 2018 from J Virol. 2018 Jun 13 (via https://www.ncbi.nlm.nih.gov/pubmed/29899102)
Zoonotic highly pathogenic avian influenza viruses (HPAIV) have raised serious public health concerns of a novel pandemic. These strains emerge from low-pathogenic precursors by acquisition of a polybasic ... Cai H, Liu M, Russell CJ. Directed evolution of an influenza reporter virus to restore replication and virulence and enhance non-invasive bioluminescence imaging in mice. J Virol. 2018 Jun 13. Abstract
submitted by kickingbird at Jun, 17, 2018 from J Virol. 2018 Jun 13 (via https://www.ncbi.nlm.nih.gov/pubmed/29899096)
Reporter viruses provide a powerful tool to study infection, yet incorporating a non-essential gene often results in virus attenuation and genetic instability. Here, we used directed evolution of a luciferase-expressing ... Fulton BO, Sun W, Heaton NS, Palese P. The influenza B virus hemagglutinin head domain is less tolerant to transposon mutagenesis than that of the influenza A virus. J Virol. 2018 Jun 13. Abstract
submitted by kickingbird at Jun, 17, 2018 from J Virol. 2018 Jun 13 (via https://www.ncbi.nlm.nih.gov/pubmed/29899093)
Influenza A and B viruses can continuously evade humoral immune responses by developing mutations in the globular head of the hemagglutinin (HA) that prevent antibody binding. However, the influenza B ... Engelhardt OG, etc.,al. Comparison of single radial immunodiffusion, SDS-PAGE and HPLC potency assays for inactivated influenza vaccines shows differences in ability to predict immunogenicity of haemagglutinin antigen. Vaccine. 2018 Jun 9. pii: S0264-410X(18)30742-4. Abstract
submitted by kickingbird at Jun, 17, 2018 from Vaccine. 2018 Jun 9. pii: S0264-410X(18)30742-4 (via https://www.ncbi.nlm.nih.gov/pubmed/29895503)
The current gold-standard potency test for inactivated influenza vaccines is the single radial immunodiffusion (SRD) assay. A number of alternative potency tests for inactivated influenza vaccines have ... Malbari K, etc.,al. In search of effective H1N1 neuraminidase inhibitor by molecular docking, antiviral evaluation and membrane interaction studies using NMR. Acta Virol. 2018;62(2):179-190. Abstract
submitted by kickingbird at Jun, 17, 2018 from Acta Virol. 2018;62(2):179-190 (via https://www.ncbi.nlm.nih.gov/pubmed/29895159)
Considering the need for discovery of new antiviral drugs, in view to combat the issue of resistance particularly to anti-influenza drugs, a series of 2'-amino, 3'-amino and 2', 4'-dihydroxy chalcone derivatives ... Chen X, Qi Y, Wang H, Wang Y, Wang H, Ni H. Prevalence of Multiple Subtypes of Avian Influenza Virus Antibodies in Egg Yolks of Mallard ( Anas platyrhynchos) and White-winged Terns ( Chlidonias leucopterus) in the Northeastern Republic of China. J Wildl Dis. 2018 Jun 12. Abstract
submitted by kickingbird at Jun, 17, 2018 from J Wildl Dis. 2018 Jun 12 (via https://www.ncbi.nlm.nih.gov/pubmed/29894211)
Wild birds are natural hosts of avian influenza viruses (AIV) and can transmit viruses to poultry and other species. To monitor the prevalence of AIV antibodies, 211 eggs from wild Mallards ( Anas platyrhynchos) ... Zhou J, etc.,al. Differentiated human airway organoids to assess infectivity of emerging influenza virus. Proc Natl Acad Sci U S A. 2018 Jun 11.. Abstract
submitted by kickingbird at Jun, 17, 2018 from Proc Natl Acad Sci U S A. 2018 Jun 11. (via https://www.ncbi.nlm.nih.gov/pubmed/29891677)
Novel reassortant avian influenza H7N9 virus and pandemic 2009 H1N1 (H1N1pdm) virus cause human infections, while avian H7N2 and swine H1N1 virus mainly infect birds and pigs, respectively. There is no ... 5328 items, 20/Page, Page[147/267][|<<] [|<] [141] [142] [143] [144] [145] [146] [147] [148] [149] [150] [>|] [>>|] |
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