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2024-7-18 3:22:53
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Murakami S, Horimoto T. Novel type D influenza virus. Uirusu. 2017;67(2):161-170.  Abstract  
submitted by kickingbird at Oct, 31, 2018 from Uirusu. 2017;67(2):161-170 (via https://www.ncbi.nlm.nih.gov/pubmed/30369540)
Influenza viruses have been known to be types A to C, including human seasonal influenza virus and avian influenza virus. In recent years, the influenza D virus, which possesses different characteristics ...

Wille M, Br?jer C, Lundkvist ?, J?rhult JD. Alternate routes of influenza A virus infection in Mallard (Anas platyrhynchos). Vet Res. 2018 Oct 29;49(1):110.  Abstract  
submitted by kickingbird at Oct, 31, 2018 from Vet Res. 2018 Oct 29;49(1):110 (via https://www.ncbi.nlm.nih.gov/pubmed/30373662)
The natural reservoir for all influenza A viruses (IAVs) is wild birds, particularly dabbling ducks. During the autumn, viral prevalence can be very high in dabbling ducks (>?30%) in the Northern Hemisphere, ...

Jochems SP, et al. Inflammation induced by influenza virus impairs human innate immune control of pneumococcus. Nat Immunol. 2018 Oct 29.  Abstract  
submitted by kickingbird at Oct, 31, 2018 from Nat Immunol. 2018 Oct 29 (via https://www.ncbi.nlm.nih.gov/pubmed/30374129)
Colonization of the upper respiratory tract by pneumococcus is important both as a determinant of disease and for transmission into the population. The immunological mechanisms that contain pneumococcus ...

Beshara R, et al. Alteration of Flt3-Ligand-dependent de novo generation of conventional dendritic cells during influenza infection contributes to respiratory bacterial superinfection. PLoS Pathog. 2018 Oct 29;14(10):e1007360..  Abstract  
submitted by kickingbird at Oct, 31, 2018 from PLoS Pathog. 2018 Oct 29;14(10):e1007360. (via https://www.ncbi.nlm.nih.gov/pubmed/30372491)
Secondary bacterial infections contribute to the excess morbidity and mortality of influenza A virus (IAV) infection. Disruption of lung integrity and impaired antibacterial immunity during IAV infection ...

Benam KH, Denney L, Ho LP. How the Respiratory Epithelium Senses and Reacts to Influenza Virus. Am J Respir Cell Mol Biol. 2018 Oct 29..  Abstract  
submitted by kickingbird at Oct, 31, 2018 from Am J Respir Cell Mol Biol. 2018 Oct 29. (via https://www.ncbi.nlm.nih.gov/pubmed/30372120)
Our lungs are constantly exposed to the environment and potential pathogens. As the interface between host and environment, the respiratory epithelium has evolved sophisticated sensing mechanisms as part ...

Li C, et al. Co-stimulation With TLR7 Agonist Imiquimod and Inactivated Influenza Virus Particles Promotes Mouse B Cell Activation, Differentiation, and Accelerated Antigen Specific Antibody Production. Front Immunol. 2018 Oct 12;9:2370..  Abstract  
submitted by kickingbird at Oct, 31, 2018 from Front Immunol. 2018 Oct 12;9:2370. (via https://www.ncbi.nlm.nih.gov/pubmed/30369932)
Current influenza vaccines have relatively low effectiveness, especially against antigenically drifted strains, the effectiveness is even lower in the elderly and immunosuppressed individuals. We have ...

Yegani S, Shoushtari AH, Eshratabadi F, Molouki A. Full sequence analysis of hemagglutinin and neuraminidase genes and proteins of highly pathogenic avian influenza H5N1 virus detected in Iran, 2015. Trop Anim Health Prod. 2018 Oct 27..  Abstract  
submitted by kickingbird at Oct, 29, 2018 from Trop Anim Health Prod. 2018 Oct 27. (via https://www.ncbi.nlm.nih.gov/pubmed/30368763)
Over the last two decades, the highly pathogenic avian influenza H5N1 virus has gained a lot of attention due to its zoonotic and mutative nature. Iran is among the countries significantly affected by ...

Deka H, Nath D, Uddin A, Chakraborty S. DNA compositional dynamics and codon usage patterns of M1 and M2 matrix protein genes in influenza A virus. Infect Genet Evol. 2018 Oct 24..  Abstract  
submitted by kickingbird at Oct, 29, 2018 from Infect Genet Evol. 2018 Oct 24. (via https://www.ncbi.nlm.nih.gov/pubmed/30367980)
Influenza A virus subtype H3N2 has been a serious health issue across the globe with approximately 36 thousand annual casualties in the United States of America only. Co-circulation in avian, swine and ...

Harland KL, et al. Limited Phenotypic and Functional Plasticity of Influenza Virus-Specific Memory CD8+ T Cells during Activation in an Alternative Cytokine Environment. J Immunol. 2018 Oct 26.  Abstract  
submitted by kickingbird at Oct, 29, 2018 from J Immunol. 2018 Oct 26 (via https://www.ncbi.nlm.nih.gov/pubmed/30366957)
Naive CD8+ T cells show phenotypic, functional, and epigenetic plasticity, enabling differentiation into distinct cellular states. However, whether memory CD8+ T cells demonstrate similar flexibility upon ...

Korenkov D, Isakova-Sivak I, Rudenko L. Basics of CD8 T-cell immune responses after influenza infection and vaccination with inactivated or live attenuated influenza vaccine. Expert Rev Vaccines. 2018 Oct 26.  Abstract  
submitted by kickingbird at Oct, 29, 2018 from Expert Rev Vaccines. 2018 Oct 26 (via https://www.ncbi.nlm.nih.gov/pubmed/30365908)
Numerous effector reactions are involved in antiviral immunity. The antibody and T-cell-mediated reactions are the best-understood processes of the adaptive immune response against influenza virus. One ...

Kim TH, Zhou H. Overexpression of Chicken IRF7 Increased Viral Replication and Programmed Cell Death to the Avian Influenza Virus Infection Through TGF-Beta/FoxO Signaling Axis in DF-1. Front Genet. 2018 Sep 25;9:415.  Abstract  
submitted by kickingbird at Oct, 27, 2018 from Front Genet. 2018 Sep 25;9:415 (via https://www.ncbi.nlm.nih.gov/pubmed/30356848)
During mammalian viral infections, interferon regulatory factor 7 (IRF7) partners with IRF3 to regulate the type I interferon response. In chickens, however, it is still unclear how IRF7 functions in the ...

An Y, Parsons LM, Jankowska E, Melnyk D, et al. N-Glycosylation of Seasonal Influenza Vaccine Hemagglutinins: Implication for potency testing and immune processing. J Virol. 2018 Oct 24..  Abstract  
submitted by kickingbird at Oct, 27, 2018 from J Virol. 2018 Oct 24. (via https://www.ncbi.nlm.nih.gov/pubmed/30355697)
Prior to each annual flu season, health authorities recommend three or four virus strains for inclusion in the annual influenza vaccine: a Type A:H1N1, a Type A:H3N2, and one or two Type B viruses. Antigenic ...

Dornfeld D, et al. Eurasian avian-like swine influenza A viruses escape human MxA restriction by distinct mutations in their nucleoprotein. J Virol. 2018 Oct 24..  Abstract  
submitted by kickingbird at Oct, 27, 2018 from J Virol. 2018 Oct 24. (via https://www.ncbi.nlm.nih.gov/pubmed/30355693)
To cross the human species barrier, influenza A viruses (IAV) of avian origin have to overcome the interferon-induced host restriction factor MxA by acquiring distinct mutations in their nucleoprotein ...

Gaba A, Xu F, Lu Y, Park HS, Liu G, Zhou Y. THE NS1 PROTEIN OF INFLUENZA A VIRUS PARTICIPATES IN NECROPTOSIS BY INTERACTING WITH MLKL AND INCREASING ITS OLIGOMERIZATION AND MEMBRANE TRANSLOCATION. J Virol. 2018 Oct 24.  Abstract  
submitted by kickingbird at Oct, 27, 2018 from J Virol. 2018 Oct 24 (via https://jvi.asm.org/content/early/2018/10/19/JVI.01835-18.lo)
Elimination of infected cells by programmed cell death is a well-recognized host defense mechanism to control the spread of infection. In addition to apoptosis, necroptosis is also one of the mechanisms ...

Santos JJS, et al. Plasticity of amino acid residue 145 near the receptor binding site of H3 swine influenza A viruses and its impact on receptor binding and antibody recognition. J Virol. 2018 Oct 24.  Abstract  
submitted by kickingbird at Oct, 27, 2018 from J Virol. 2018 Oct 24 (via https://www.ncbi.nlm.nih.gov/pubmed/30355680)
The hemagglutinin (HA), a glycoprotein on the surface of influenza A virus (IAV), initiates the virus life cycle by binding to terminal sialic acid (SA) residues on host cells. The HA gradually accumulates ...

Hird SM, Ganz H, Eisen JA, Boyce WM. The Cloacal Microbiome of Five Wild Duck Species Varies by Species and Influenza A Virus Infection Status. mSphere. 2018 Oct 24;3(5)..  Abstract  
submitted by kickingbird at Oct, 27, 2018 from mSphere. 2018 Oct 24;3(5). (via https://www.ncbi.nlm.nih.gov/pubmed/30355662)
Waterfowl, especially ducks of the genus Anas, are natural reservoir species for influenza A virus (IAV). Duck populations contain nearly all the known diversity of IAVs, and the birds are asymptomatic ...

Wu H, Yang F, Liu F, Lu R, Peng X, Chen B, Yao H. Isolation and characterization of novel reassortant H6N1 avian influenza viruses from chickens in Eastern China. Virol J. 2018 Oct 24;15(1):164..  Abstract  
submitted by kickingbird at Oct, 27, 2018 from Virol J. 2018 Oct 24;15(1):164. (via https://www.ncbi.nlm.nih.gov/pubmed/30355336)
BACKGROUND: The H6N1 subtype of avian influenza viruses (AIVs) can infect people with an influenza-like illness; the H6N1 viruses possess the ability for zoonotic transmission from avians into mammals, ...

Wei D, et al. Genome-wide characterization of the seasonal H3N2 virus in Shanghai reveals natural temperature-sensitive strains conferred by the I668V mutation in the PA subunit. Emerg Microbes Infect. 2018 Oct 23;7(1):171.  Abstract  
submitted by kickingbird at Oct, 27, 2018 from Emerg Microbes Infect. 2018 Oct 23;7(1):171 (via https://www.ncbi.nlm.nih.gov/pubmed/30353004)
Seasonal H3N2 influenza viruses are recognized as major epidemic viruses, exhibiting complex seasonal patterns in regions with temperate climates. To investigate the influence of viral evolution and mutations ...

Bedi S, Noda T, Kawaoka Y, Ono A. A Defect in Influenza A Virus Particle Assembly Specific to Primary Human Macrophages. MBio. 2018 Oct 23;9(5).  Abstract  
submitted by kickingbird at Oct, 27, 2018 from MBio. 2018 Oct 23;9(5) (via https://www.ncbi.nlm.nih.gov/pubmed/30352935)
Influenza A virus (IAV) propagates efficiently in epithelial cells, its primary target in the respiratory tract. In contrast, productive infection of most IAV strains is either blocked or highly inefficient ...

Goldhill DH, et al. The mechanism of resistance to favipiravir in influenza. Proc Natl Acad Sci U S A. 2018 Oct 23..  Abstract  
submitted by kickingbird at Oct, 27, 2018 from Proc Natl Acad Sci U S A. 2018 Oct 23. (via https://www.ncbi.nlm.nih.gov/pubmed/30352857)
Favipiravir is a broad-spectrum antiviral that has shown promise in treatment of influenza virus infections. While emergence of resistance has been observed for many antiinfluenza drugs, to date, clinical ...

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