Koutsakos M, et al. Human CD8+ T cell cross-reactivity across influenza A, B and C viruses. Nat Immunol. 2019 Feb 18.. Abstract
submitted by kickingbird at Feb, 21, 2019 from Nat Immunol. 2019 Feb 18. (via https://www.nature.com/articles/s41590-019-0320-6)
Influenza A, B and C viruses (IAV, IBV and ICV, respectively) circulate globally and infect humans, with IAV and IBV causing the most severe disease. CD8+ T cells confer cross-protection against IAV strains, ... Rüdiger D, Kupke SY, Laske T, Zmora P, Reichl U. Multiscale modeling of influenza A virus replication in cell cultures predicts infection dynamics for highly different infection conditions. PLoS Comput Biol. 2019 Feb 19;15(2):e1006819.. Abstract
submitted by kickingbird at Feb, 21, 2019 from PLoS Comput Biol. 2019 Feb 19;15(2):e1006819. (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Influenza A viruses (IAV) are commonly used to infect animal cell cultures for research purposes and vaccine production. Their replication is influenced strongly by the multiplicity of infection (MOI), ... Ilyushina NA, Dickensheets H, Donnelly RP. A comparison of interferon gene expression induced by influenza A virus infection of human airway epithelial cells from two different donors. Virus Res. 2019 Feb 16. Abstract
submitted by kickingbird at Feb, 21, 2019 from Virus Res. 2019 Feb 16 (via https://www.ncbi.nlm.nih.gov/pubmed/30779949)
Influenza is an acute respiratory disease that can cause local annual epidemics and worldwide pandemics of different morbidity and mortality. Our understanding of host factors that modulate the frequency ... Ren L, et al. Influenza A virus (H1N1) triggers a hypoxic response by stabilizing hypoxia-inducible factor-1α via inhibition of proteasome. Virology. 2019 Feb 11;530:51-58. Abstract
submitted by kickingbird at Feb, 21, 2019 from Virology. 2019 Feb 11;530:51-58 (via https://www.ncbi.nlm.nih.gov/pubmed/30780125)
Virus reprogramming of host cellular function is a critical strategy for viral survival and replication. A better understanding of virus-host interaction may provide new potential avenues for the treatment ... Roy Chowdhury I, Yeddula SGR, Kim SH. Pathogenicity and Transmissibility of North American H7 Low Pathogenic Avian Influenza Viruses in Chickens and Turkeys. Viruses. 2019 Feb 16;11(2). Abstract
submitted by kickingbird at Feb, 21, 2019 from Viruses. 2019 Feb 16;11(2) (via https://www.ncbi.nlm.nih.gov/pubmed/30781528)
Low pathogenic avian influenza (LPAI) viruses can silently circulate in poultry and wild aquatic birds and potentially mutate into highly pathogenic avian influenza (HPAI) viruses. In the U.S., recent ... Zhang T, Zhao H, Wang J, Han GZ. Wild birds do not harbor higher diversity of influenza virus internal genes than poultry. Virology. 2019 Feb 7;530:59-64. Abstract
submitted by kickingbird at Feb, 20, 2019 from Virology. 2019 Feb 7;530:59-64 (via https://www.ncbi.nlm.nih.gov/pubmed/30776509)
Avian influenza A virus (AIV) has threatened global economy and public health. Wild birds have long been thought to serve as the natural reservoir of influenza virus, and thus it is expected that wild ... Hu Q, Gilley RP, Dube PH. House dust mite exposure attenuates influenza A infection in a mouse model of pulmonary allergic inflammation. Microb Pathog. 2019 Feb 15.. Abstract
submitted by kickingbird at Feb, 20, 2019 from Microb Pathog. 2019 Feb 15. (via https://www.ncbi.nlm.nih.gov/pubmed/30776411)
Environmental allergens elicit complex immune responses in the lungs that can promote the development of asthma or exacerbate preexisting asthma in susceptible individuals. House dust mites are one of ... Fu Y, et al. Infection Studies in Pigs and Porcine Airway Epithelial Cells Reveal an Evolution of A(H1N1)pdm09 Influenza A Viruses Toward Lower Virulence. J Infect Dis. 2019 Feb 18.. Abstract
submitted by kickingbird at Feb, 20, 2019 from J Infect Dis. 2019 Feb 18. (via https://www.ncbi.nlm.nih.gov/pubmed/30776304)
We analyzed the virulence of pandemic H1N1 2009 influenza A viruses in vivo and in vitro. Selected viruses isolated in 2009, 2010, 2014, and 2015 were assessed using an aerosol-mediated high-dose infection ... Cao Y, et al. Global transcriptome analysis of H5N1 influenza virus-infected human cells. Hereditas. 2019 Feb 6;156:10. Abstract
submitted by kickingbird at Feb, 20, 2019 from Hereditas. 2019 Feb 6;156:10 (via https://www.ncbi.nlm.nih.gov/pubmed/30774581)
Background: Influenza A virus (IAV) belongs to the Orthomyxoviridae family. IAV causes a highly contagious respiratory disease in humans that exacts severe economic losses globally. The virus uses strategies ... Curthoys NM, et al. Influenza Hemagglutinin Modulates Phosphatidylinositol 4,5-bisphosphate Membrane Clustering. Biophys J. 2019 Jan 25.. Abstract
submitted by kickingbird at Feb, 20, 2019 from Biophys J. 2019 Jan 25. (via https://www.ncbi.nlm.nih.gov/pubmed/30773293)
The lipid phosphatidylinositol 4,5-bisphosphate (PIP2) forms nanoscopic clusters in cell plasma membranes; however, the processes determining PIP2 mobility and thus its spatial patterns are not fully understood. ... Dumm RE, et al. Non-lytic clearance of influenza B virus from infected cells preserves epithelial barrier function. Nat Commun. 2019 Feb 15;10(1):779. Abstract
submitted by kickingbird at Feb, 19, 2019 from Nat Commun. 2019 Feb 15;10(1):779 (via https://www.ncbi.nlm.nih.gov/pubmed/30770807)
Influenza B virus (IBV) is an acute, respiratory RNA virus that has been assumed to induce the eventual death of all infected cells. We and others have shown however, that infection with apparently cytopathic ... Yeming Wang, et al. Comparative outcomes of adults hospitalized with seasonal influenza A or B virus infection: application of the seven-category ordinal scale. Open Forum Infectious Diseases 15 February 2019. Abstract
submitted by kickingbird at Feb, 19, 2019 from Open Forum Infectious Diseases 15 February 2019 (via https://academic.oup.com/ofid/advance-article/doi/10.1093/of)
ObjectiveTo investigate the difference of disease severity between influenza A and B among hospitalized adults using a novel ordinal scale and existing clinical outcome endpoints.MethodsA prospective, ... James J, et al. The cellular localization of avian influenza virus PB1-F2 protein alters the magnitude of IFN2 promoter and NFκB-dependent promoter antagonism in chicken cells. J Gen Virol. 2019 Jan 23.. Abstract
submitted by kickingbird at Feb, 18, 2019 from J Gen Virol. 2019 Jan 23. (via https://www.ncbi.nlm.nih.gov/pubmed/30672726)
The accessory protein, PB1-F2, of influenza A virus (IAV) functions in a chicken host to prolong infectious virus shedding and thus the transmission window. Here we show that this delay in virus clearance ... Bolte H, et al. Packaging of the Influenza Virus Genome Is Governed by a Plastic Network of RNA- and Nucleoprotein-Mediated Interactions. J Virol. 2019 Feb 5;93(4). Abstract
submitted by kickingbird at Feb, 17, 2019 from J Virol. 2019 Feb 5;93(4) (via https://www.ncbi.nlm.nih.gov/pubmed/30463968)
The genome of influenza A virus is organized into eight ribonucleoproteins, each composed of a distinct RNA segment bound by the viral polymerase and oligomeric viral nucleoprotein. Packaging sequences ... White MC1, Tao H, Steel J, Lowen AC. H5N8 and H7N9 packaging signals constrain HA reassortment with a seasonal H3N2 influenza A virus. Proc Natl Acad Sci U S A. 2019 Feb 13. Abstract
submitted by kickingbird at Feb, 16, 2019 from Proc Natl Acad Sci U S A. 2019 Feb 13 (via https://www.ncbi.nlm.nih.gov/pubmed/30760600)
Influenza A virus (IAV) has a segmented genome, which (i) allows for exchange of gene segments in coinfected cells, termed reassortment, and (ii) necessitates a selective packaging mechanism to ensure ... Ito M, et al. Characterization of Mouse Monoclonal Antibodies Against the HA of A(H7N9) Influenza Virus. Viruses. 2019 Feb 11;11(2). Abstract
submitted by kickingbird at Feb, 16, 2019 from Viruses. 2019 Feb 11;11(2) (via https://www.ncbi.nlm.nih.gov/pubmed/30754701)
Many cases of human infection with the H7N9 virus have been detected in China since 2013. H7N9 viruses are maintained in chickens and are transmitted to humans at live bird markets. During circulation ... Vrijens P, et al. Influenza virus entry via the GM3 ganglioside-mediated platelet-derived growth factor receptor β signalling pathway. J Gen Virol. 2019 Feb 14.. Abstract
submitted by kickingbird at Feb, 16, 2019 from J Gen Virol. 2019 Feb 14. (via https://www.ncbi.nlm.nih.gov/pubmed/30762518)
The possible resistance of influenza virus against existing antiviral drugs calls for new therapeutic concepts. One appealing strategy is to inhibit virus entry, in particular at the stage of internalization. ... Kargarfard F, Sami A, Hemmatzadeh F, Ebrahimie E. Identifying mutation positions in all segments of influenza genome enables better differentiation between pandemic and seasonal strains. Gene. 2019 Feb 12. pii: S0378-1119(19)30058-7.. Abstract
submitted by kickingbird at Feb, 16, 2019 from Gene. 2019 Feb 12. pii: S0378-1119(19)30058-7. (via https://www.ncbi.nlm.nih.gov/pubmed/30769139)
Influenza has a negative sense, single-stranded, segmented RNA. In the context of pandemic influenza research, most studies have focused on variations in the surface proteins (Hemagglutinin and Neuraminidase). ... Nikolaev EV, Zloza A, Sontag ED. Immunobiochemical Reconstruction of Influenza Lung Infection-Melanoma Skin Cancer Interactions. Front Immunol. 2019 Jan 28;10:4. Abstract
submitted by kickingbird at Feb, 14, 2019 from Front Immunol. 2019 Jan 28;10:4 (via https://www.ncbi.nlm.nih.gov/pubmed/30745900)
It was recently reported that acute influenza infection of the lung promoted distal melanoma growth in the dermis of mice. Melanoma-specific CD8+ T cells were shunted to the lung in the presence of the ... Kwon JH, et al. Different pathogenicity of two strains of clade 2.3.4.4c H5N6 highly pathogenic avian influenza viruses bearing different PA and NS gene in domestic ducks. Virology. 2019 Jan 15;530:11-18. Abstract
submitted by kickingbird at Feb, 14, 2019 from Virology. 2019 Jan 15;530:11-18 (via https://www.ncbi.nlm.nih.gov/pubmed/30753976)
H5Nx clade 2.3.4.4 highly pathogenic avian influenza viruses (HPAIVs) have been disseminated to wide geographic regions since 2014. In 2016, five distinct genotypes (C-1 to C-5) of clade 2.3.4.4c H5N6 ... 5328 items, 20/Page, Page[120/267][|<<] [|<] [111] [112] [113] [114] [115] [116] [117] [118] [119] [120] [>|] [>>|] |
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