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2024-7-17 23:29:19
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Bradley KC, et al. Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection. Cell Rep. 2019 Jul 2;28(1):245-256.e4.  Abstract  
submitted by kickingbird at Jul, 7, 2019 from Cell Rep. 2019 Jul 2;28(1):245-256.e4 (via https://www.cell.com/cell-reports/fulltext/S2211-1247(19)307)
Type I interferon (IFNα/β) pathways are fine-tuned to elicit antiviral protection while minimizing immunopathology; however, the initiating stimuli, target tissues, and underlying mechanisms are unclear. ...

Li X, Gao Y, Ye Z. A Single Amino Acid Substitution at Residue 218 of Hemagglutinin Improves the Growth of Influenza A(H7N9) Candidate Vaccine Viruses. J Virol. 2019 Jul 3. pii: JVI.00570-19.  Abstract  
submitted by kickingbird at Jul, 7, 2019 from J Virol. 2019 Jul 3. pii: JVI.00570-19 (via https://jvi.asm.org/content/early/2019/06/27/JVI.00570-19)
The potential avian influenza pandemic remains a threat to public health, as the avian-originated influenza A(H7N9) virus has caused more than 1560 laboratory-confirmed human infections since 2013, with ...

Cohen L, et al. A Modular Cytokine Analysis Method Reveals Novel Associations With Clinical Phenotypes and Identifies Sets of Co-signaling Cytokines Across Influenza Natural Infection Cohorts and Healthy Controls. Front Immunol. 2019 Jun 18.  Abstract  
submitted by kickingbird at Jul, 7, 2019 from Front Immunol. 2019 Jun 18 (via https://www.frontiersin.org/articles/10.3389/fimmu.2019.0133)
Cytokines and chemokines are key signaling molecules of the immune system. Recent technological advances enable measurement of multiplexed cytokine profiles in biological samples. These profiles can then ...

Boumart Z, et al. Pathogenicity and Full Genome Sequencing of the Avian Influenza H9N2 Moroccan Isolate 2016. Avian Dis. 2018 Nov 16;63(1):24-30.  Abstract  
submitted by kickingbird at Jul, 2, 2019 from Avian Dis. 2018 Nov 16;63(1):24-30 (via https://bioone.org/journals/Avian-Diseases/volume-63/issue-1)
In Morocco in early 2016, a low pathogenic avian influenza virus serotype H9N2 caused large economic losses to the poultry industry, with specific clinical symptoms and high mortality rates on infected ...

Guo F, et al. Adaptive Evolution of Human-Isolated H5Nx Avian Influenza A Viruses. Front Microbiol. 2019 Jun 12;10:1328.  Abstract  
submitted by kickingbird at Jul, 2, 2019 from Front Microbiol. 2019 Jun 12;10:1328 (via https://www.frontiersin.org/articles/10.3389/fmicb.2019.0132)
Avian influenza A viruses (AIVs) H5N1, first identified in 1996, are highly pathogenic in domestic poultry and continue to occasionally infect humans. In this study, we sought to identify genetic changes ...

Spackman E, et al. Clade 2.3.4.4 H5 North American Highly Pathogenic Avian Influenza Viruses Infect, but Do Not Cause Clinical Signs in, American Black Ducks (Anas rubripes).. Avian Dis. 2019 Jan 18;63(2):366-370.  Abstract  
submitted by kickingbird at Jul, 2, 2019 from Avian Dis. 2019 Jan 18;63(2):366-370 (via https://www.ncbi.nlm.nih.gov/pubmed/31251539)
Highly pathogenic avian influenza virus (HPAIV) from the goose/Guangdong/1996 clade 2.3.4.4 H5 lineage spread from Asia into North America in 2014, most likely by wild bird migrations. Although several ...

Mine J, et al. Phylogeographic evidence for the inter-and intracontinental dissemination of avian influenza viruses via migration flyways. PLoS One. 2019 Jun 26;14(6):e0218506..  Abstract  
submitted by kickingbird at Jun, 28, 2019 from PLoS One. 2019 Jun 26;14(6):e0218506. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Genetically related highly pathogenic avian influenza viruses (HPAIVs) of H5N6 subtype caused outbreaks simultaneously in East Asia and Europe-geographically distinct regions-during winter 2017-2018. This ...

Zhuang Q, et al. Diversity and distribution of type A influenza viruses: an updated panorama analysis based on protein sequences. Virol J. 2019 Jun 26;16(1):85.  Abstract  
submitted by kickingbird at Jun, 28, 2019 from Virol J. 2019 Jun 26;16(1):85 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
BACKGROUND: Type A influenza viruses (IAVs) cause significant infections in humans and multiple species of animals including pigs, horses, birds, dogs and some marine animals. They are of complicated phylogenetic ...

Leach S, et al. Requirement for memory B cell activation in protection from heterologous influenza virus reinfection. Int Immunol. 2019 Jun 20..  Abstract  
submitted by kickingbird at Jun, 25, 2019 from Int Immunol. 2019 Jun 20. (via https://academic.oup.com/intimm/advance-article-abstract/doi)
While two memory compartments, memory B cells and long-lived plasma cells, are thought to contribute to the successful establishment of memory recall responses, the unique roles of each cellular compartment ...

Yan HX, Xu HF, He WJ, Xie Y, Dong GY.. Phylogenetic analysis of HA and NA genes of influenza H1N1 viruses from 1918 to 2017. Acta Virol. 2019;63(2):195-202..  Abstract  
submitted by kickingbird at Jun, 25, 2019 from Acta Virol. 2019;63(2):195-202. (via https://www.ncbi.nlm.nih.gov/pubmed/31230448)
The 1918 "Spanish" pandemic is the earliest known influenza H1N1 virus. Since then H1N1 viruses circulated between humans and animals continuously. With the increased amount of samples of H1N1 viruses ...

Ma MJ, et al. Characterization of antibody and memory T cell response in H7N9 survivors: A cross-sectional analysis. Clin Microbiol Infect. 2019 Jun 20.  Abstract  
submitted by kickingbird at Jun, 25, 2019 from Clin Microbiol Infect. 2019 Jun 20 (via https://www.clinicalmicrobiologyandinfection.com/article/S11)
OBJECTIVES: Despite the importance of immunological memory for protective immunity against viral infection, whether H7N9-specific antibodies and memory T-cell responses remain detectable years after the ...

Adams SE, et al. Effect of influenza H1N1 neuraminidase V116A and I117V mutations on NA activity and sensitivity to NA inhibitors. Antiviral Res. 2019 Jun 19:104539..  Abstract  
submitted by kickingbird at Jun, 24, 2019 from Antiviral Res. 2019 Jun 19:104539. (via https://www.sciencedirect.com/science/article/pii/S016635421)
Neuraminidase inhibitors (NAIs) play a key role in the management of influenza. Given the limited number of FDA-approved anti-influenza drugs, evaluation of potential drug-resistant variants is of high ...

Nemoto M, et al. A single amino acid change in hemagglutinin reduces the cross-reactivity of antiserum against an equine influenza vaccine strain. Arch Virol. 2019 Jun 21..  Abstract  
submitted by kickingbird at Jun, 24, 2019 from Arch Virol. 2019 Jun 21. (via https://link.springer.com/article/10.1007%2Fs00705-019-04328)
Equine influenza virus is an important pathogen for the horse industry because of its economic impact, and vaccination is a key control measure. Our previous work suggested that a mutation at position ...

Prier JE, et al. Early T-BET Expression Ensures an Appropriate CD8+ Lineage-Specific Transcriptional Landscape after Influenza A Virus Infection. J Immunol. 2019 Jun 21..  Abstract  
submitted by kickingbird at Jun, 24, 2019 from J Immunol. 2019 Jun 21. (via https://www.jimmunol.org/content/early/2019/06/21/jimmunol.1)
Virus infection triggers large-scale changes in the phenotype and function of naive CD8+ T cells, resulting in the generation of effector and memory T cells that are then critical for immune clearance. ...

Xiao Y, et al. Deep sequencing of 2009 influenza A/H1N1 virus isolated from volunteer human challenge study participants and natural infections. Virology. 2019 Jun 13;534:96-107..  Abstract  
submitted by kickingbird at Jun, 23, 2019 from Virology. 2019 Jun 13;534:96-107. (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Nasal wash samples from 15 human volunteers challenged with GMP manufactured influenza A/California/04/2009(H1N1) and from 5 naturally infected influenza patients of the 2009 pandemic were deep sequenced ...

Nichols JE, Niles JA, Fleming EH, Roberts NJ. The role of cell surface expression of influenza virus neuraminidase in induction of human lymphocyte apoptosis. Virology. 2019 Jun 10;534:80-86..  Abstract  
submitted by kickingbird at Jun, 21, 2019 from Virology. 2019 Jun 10;534:80-86. (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
The immunopathological mechanisms as well as the role played by influenza A virus infection of human leukocytes and induction of apoptosis have not been fully elucidated. We confirm here that the percentage ...

Liu JH, Chang CC, Chen CW, Wong LT, Chu YW. Conservation Region Finding for Influenza A Viruses by Machine Learning methods of N-linked Glycosylation Sites and B-cell Epitopes. Math Biosci. 2019 Jun 17:108217.  Abstract  
submitted by kickingbird at Jun, 21, 2019 from Math Biosci. 2019 Jun 17:108217 (via https://www.sciencedirect.com/science/article/abs/pii/S00255)
Influenza type A, a serious infectious disease of the human respiratory tract, poses an enormous threat to human health worldwide. It leads to high mortality rates in poultry, pigs, and humans. The primary ...

Li X, Xu B, Shaman J. Pathobiological features favouring the intercontinental dissemination of highly pathogenic avian influenza virus. R Soc Open Sci. 2019 May 8;6(5):190276.  Abstract  
submitted by kickingbird at Jun, 21, 2019 from R Soc Open Sci. 2019 May 8;6(5):190276 (via https://royalsocietypublishing.org/doi/10.1098/rsos.190276)
Avian influenza viruses (AIVs) are a continued threat to global health and economy. Unlike other highly pathogenic AIVs, novel H5N8 disseminated very quickly from Korea to other areas in Asia, Europe and ...

Spencer S, Thompson MG, Flannery B, Fry A. Comparison of Respiratory Specimen Collection Methods for Detection of Influenza Virus Infection by RT-PCR: A Literature Review. J Clin Microbiol. 2019 Jun 19..  Abstract  
submitted by kickingbird at Jun, 21, 2019 from J Clin Microbiol. 2019 Jun 19. (via https://jcm.asm.org/content/early/2019/06/17/JCM.00027-19)
Detection of influenza virus in respiratory specimens from ill individuals is the most commonly used method to identify influenza virus infection. A number of respiratory specimen types may be used, including ...

Staller E, et al. ANP32 proteins are essential for influenza virus replication in human cells. J Virol. 2019 Jun 19..  Abstract  
submitted by kickingbird at Jun, 21, 2019 from J Virol. 2019 Jun 19. (via https://jvi.asm.org/content/early/2019/06/13/JVI.00217-19)
ANP32 proteins have been implicated in supporting influenza virus replication, but most of the work to date has focused on the ability of avian Anp32 proteins to overcome restriction of avian influenza ...

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