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2024-5-3 21:17:52
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Okuda M, et al. Subclade 2.2.1-Specific Human Monoclonal Antibodies That Recognize an Epitope in Antigenic Site A of Influenza A(H5) Virus HA Detected between 2015 and 2018. Viruses. 2019 Apr 2;11(4)..  Abstract  
submitted by kickingbird at Apr, 17, 2019 from Viruses. 2019 Apr 2;11(4). (via https://www.mdpi.com/1999-4915/11/4/321)
Highly pathogenic avian H5 influenza viruses persist among poultry and wild birds throughout the world. They sometimes cause interspecies transmission between avian and mammalian hosts. H5 viruses possessing ...

Wellington D, et al. IFITM3: How genetics influence influenza infection demographically. Biomed J. 2019 Feb;42(1):19-26..  Abstract  
submitted by kickingbird at Apr, 17, 2019 from Biomed J. 2019 Feb;42(1):19-26. (via https://www.sciencedirect.com/science/article/pii/S231941701)
The role of host genetics in influenza infection is unclear despite decades of interest. Confounding factors such as age, sex, ethnicity and environmental factors have made it difficult to assess the role ...

Biondo C, Lentini G, Beninati C, Teti G. The dual role of innate immunity during influenza. Biomed J. 2019 Feb;42(1):8-18..  Abstract  
submitted by kickingbird at Apr, 17, 2019 from Biomed J. 2019 Feb;42(1):8-18. (via https://www.sciencedirect.com/science/article/pii/S231941701)
One of the distinguishing features of the 1918 pandemic is the occurrence of massive, potentially detrimental, activation of the innate immune system in critically ill patients. Whether this reflects an ...

Park ES, et al. Co-degradation of interferon signaling factor DDX3 by PB1-F2 as a basis for high virulence of 1918 pandemic influenza. EMBO J. 2019 Apr 12.  Abstract  
submitted by kickingbird at Apr, 15, 2019 from EMBO J. 2019 Apr 12 (via http://emboj.embopress.org/content/early/2019/04/12/embj.201)
The multifunctional influenza virus protein PB1-F2 plays several roles in deregulation of host innate immune responses and is a known immunopathology enhancer of the 1918 influenza pandemic. Here, we show ...

Yang J, et al. Ducks induce rapid and robust antibody responses than chickens at early time after intravenous infection with H9N2 avian influenza virus. Virol J. 2019 Apr 11;16(1):46..  Abstract  
submitted by kickingbird at Apr, 14, 2019 from Virol J. 2019 Apr 11;16(1):46. (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
BACKGROUND: Compared with chickens, ducks are normally resistant to avian influenza virus without clinical signs while they habor almost all subtypes of influenza A viruses. To date, however the mechanism ...

Tao P, Ning Z, Hao X, Lin X, Zheng Q, Li S. Comparative Analysis of Whole-Transcriptome RNA Expression in MDCK Cells Infected With the H3N2 and H5N1 Canine Influenza Viruses. Front Cell Infect Microbiol. 2019 Mar 26;9:76.  Abstract  
submitted by kickingbird at Apr, 12, 2019 from Front Cell Infect Microbiol. 2019 Mar 26;9:76 (via https://www.frontiersin.org/articles/10.3389/fcimb.2019.0007)
This study aimed to detect changes in the complete transcriptome of MDCK cells after infection with the H5N1 and H3N2 canine influenza viruses using high-throughput sequencing, search for differentially ...

Bergervoet SA, et al. Genetic analysis identifies potential transmission of low pathogenic avian influenza viruses between poultry farms. Transbound Emerg Dis. 2019 Apr 9..  Abstract  
submitted by kickingbird at Apr, 11, 2019 from Transbound Emerg Dis. 2019 Apr 9. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13199)
Poultry can become infected with low pathogenic avian influenza (LPAI) viruses via (in)direct contact with infected wild birds, or by transmission of the virus between farms. This study combines routinely ...

Xie C, et al. Detection of influenza and other respiratory viruses in air sampled from a university campus: a longitudinal study. Clin Infect Dis. 2019 Apr 9..  Abstract  
submitted by kickingbird at Apr, 11, 2019 from Clin Infect Dis. 2019 Apr 9. (via https://academic.oup.com/cid/advance-article-abstract/doi/10)
BACKGROUND: Respiratory virus-laden particles are commonly detected in the exhaled breath of symptomatic patients or in air sampled from healthcare settings. However, the temporal relationship of detecting ...

Sugishita Y, Sugawara T, Ohkusa Y. Association of influenza outbreak in each nursery school and community in a ward in Tokyo, Japan. J Infect Chemother. 2019 Apr 6..  Abstract  
submitted by kickingbird at Apr, 11, 2019 from J Infect Chemother. 2019 Apr 6. (via https://www.ncbi.nlm.nih.gov/pubmed/30962116)
In nursery schools, influenza outbreaks have occurred every year. However, influenza characteristics of its diffusion among nursery schools, within each nursery school, and among classes of different ages ...

Ladman BS, et al. Protection Afforded By Avian Influenza Vaccination Programs Consisting Of A Novel RNA Particle And An Inactivated Avian Influenza Vaccine Against A Highly Pathogenic Avian Influenza Virus Challenge In. Avian Pathol. 2019 Apr 9:1-34.  Abstract  
submitted by kickingbird at Apr, 11, 2019 from Avian Pathol. 2019 Apr 9:1-34 (via https://www.tandfonline.com/doi/abs/10.1080/03079457.2019.16)
The efficacies of an oil adjuvanted-inactivated reverse genetics derived H5 avian influenza virus (AIV) vaccine and an alphavirus replicon RNA particle (RP) AIV vaccine were evaluated in commercial leghorn ...

Carnaccini S, et al. Age-dependent pathogenesis of clade 2.3.4.4A H5N2 HPAIV in experimentally infected Broad Breasted White turkeys. Vet Microbiol. 2019 Apr;231:183-190.  Abstract  
submitted by kickingbird at Apr, 9, 2019 from Vet Microbiol. 2019 Apr;231:183-190 (via https://www.sciencedirect.com/science/article/pii/S037811351)
Highly pathogenic avian influenza (HPAI) is a viral disease with devastating consequences to the poultry industry as it results in high morbidity, mortality and international trade restrictions. In the ...

Zhang X, et al. Pathogenesis of co-infections of influenza D virus and Mannheimia haemolytica in cattle. Vet Microbiol. 2019 Apr;231:246-253..  Abstract  
submitted by kickingbird at Apr, 9, 2019 from Vet Microbiol. 2019 Apr;231:246-253. (via https://www.sciencedirect.com/science/article/pii/S037811351)
Bovine respiratory disease (BRD) is economically significant, and influenza D virus (IDV) is commonly identified in cattle with BRD. Mannheimia haemolytica (MHA) is an opportunistic bacterial contributor ...

Mamerow S, et al. Double-attenuated influenza virus elicits broad protection against challenge viruses with different serotypes in swine. Vet Microbiol. 2019 Apr;231:160-168..  Abstract  
submitted by kickingbird at Apr, 9, 2019 from Vet Microbiol. 2019 Apr;231:160-168. (via https://www.sciencedirect.com/science/article/pii/S037811351)
Influenza A viruses (IAV) have caused seasonal epidemics and severe pandemics in humans. Novel pandemic strains as in 2009 may emerge from pigs, serving as perpetual virus reservoir. However, reliably ...

Marr LC, Tang JW, Van Mullekom J, Lakdawala SS. Mechanistic insights into the effect of humidity on airborne influenza virus survival, transmission and incidence. J R Soc Interface. 2019 Jan 31;16(150):20180298.  Abstract  
submitted by kickingbird at Apr, 9, 2019 from J R Soc Interface. 2019 Jan 31;16(150):20180298 (via https://royalsocietypublishing.org/doi/10.1098/rsif.2018.029)
Influenza incidence and seasonality, along with virus survival and transmission, appear to depend at least partly on humidity, and recent studies have suggested that absolute humidity (AH) is more important ...

Andronico A, et al. Highly pathogenic avian influenza H5N8 in south-west France 2016-2017: A modeling study of control strategies. Epidemics. 2019 Mar 28.  Abstract  
submitted by kickingbird at Apr, 7, 2019 from Epidemics. 2019 Mar 28 (via https://www.sciencedirect.com/science/article/pii/S175543651)
In the winter 2016-2017 the largest epidemic of highly pathogenic avian influenza (HPAI) ever recorded in the European Union spread to all 28 member states. France was hit particularly hard and reported ...

Bo?i? B, et al. Comparative pathological findings in mute swans (Cygnus olor) naturally infected with highly pathogenic Avian influenza viruses H5N1 and H5N8 in Serbia. Vet Ital. 2019 Mar 31;55(1):95-101.  Abstract  
submitted by kickingbird at Apr, 7, 2019 from Vet Ital. 2019 Mar 31;55(1):95-101 (via http://www.izs.it/vet_italiana/2019/55_1/VetIt_1463_7919_2.p)
The aim of this study was to compare pathological lesions and viral antigen expression in the organs of mute swans (Cygnus olor) naturally infected with highly pathogenic avian influenza virus subtypes ...

Sun W, et al. Development of Influenza B Universal Vaccine Candidates using the “Mosaic” Hemagglutinin Approach. J Virol. 2019 Apr 3..  Abstract  
submitted by kickingbird at Apr, 6, 2019 from J Virol. 2019 Apr 3. (via https://jvi.asm.org/content/early/2019/03/28/JVI.00333-19)
Influenza B viruses cause seasonal epidemics and are a considerable burden to public health. However, protection by current seasonal vaccines is suboptimal due to the antigenic changes of the circulating ...

Akole A, Warner JM. Model of influenza virus acidification. PLoS ONE 14(4): e0214448..  Abstract  
submitted by kickingbird at Apr, 6, 2019 from PLoS ONE 14(4): e0214448. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Internal acidification of the influenza virus, mediated by the M2 proton channel, is a key step in its life cycle. The interior M1 protein shell dissolves at pH~5.5 to 6.0, allowing the release of vRNA ...

Ciminski K, et al. Human MxA is a potent interspecies barrier for the novel bat-derived influenza A-like virus H18N11. Emerg Microbes Infect. 2019;8(1):556-563..  Abstract  
submitted by kickingbird at Apr, 5, 2019 from Emerg Microbes Infect. 2019;8(1):556-563. (via https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1)
The human innate immune factor MxA represents an effective interspecies barrier for zoonotic influenza A viruses (IAVs) of animal origin. Accordingly, human but not avian IAVs efficiently escape the antiviral ...

Altman MO, et al. Human Influenza A Virus Hemagglutinin Glycan Evolution Follows a Temporal Pattern to a Glycan Limit. MBio. 2019 Apr 2;10(2)..  Abstract  
submitted by kickingbird at Apr, 5, 2019 from MBio. 2019 Apr 2;10(2). (via https://mbio.asm.org/content/10/2/e00204-19)
Human antibody-based immunity to influenza A virus is limited by antigenic drift resulting from amino acid substitutions in the hemagglutinin (HA) head domain. Glycan addition can cause large antigenic ...

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