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2025-12-19 2:52:50
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Guo X, Zhou Y, Yan H, An Q, Liang C, Liu L, Qian J. Molecular Markers and Mechanisms of Influenza A Virus Cross-Species Transmission and New Host Adaptation. Viruses. 2024 May 30;16(6):88.  Abstract  
submitted by kickingbird at Jun, 28, 2024 from Viruses. 2024 May 30;16(6):88 (via https://www.mdpi.com/1999-4915/16/6/883)
Influenza A viruses continue to be a serious health risk to people and result in a large-scale socio-economic loss. Avian influenza viruses typically do not replicate efficiently in mammals, but through ...

Warren CJ, Brookes SM, Arnold ME, Irvine RM, Hanse. Assessment of Survival Kinetics for Emergent Highly Pathogenic Clade 2.3.4.4 H5Nx Avian Influenza Viruses. Viruses. 2024 May 31;16(6):889.  Abstract  
submitted by kickingbird at Jun, 28, 2024 from Viruses. 2024 May 31;16(6):889 (via https://www.mdpi.com/1999-4915/16/6/889)
High pathogenicity avian influenza viruses (HPAIVs) cause high morbidity and mortality in poultry species. HPAIV prevalence means high numbers of infected wild birds could lead to spill over events for ...

Shimizu K, Kawakami C, Matsuzaki Y, Fujisaki S, Na. Monitoring Influenza C and D Viruses in Patients With Respiratory Diseases in Japan, January 2018 to March 2023. Influenza Other Respir Viruses. 2024 Jun;18(6):e13.  Abstract  
submitted by kickingbird at Jun, 27, 2024 from Influenza Other Respir Viruses. 2024 Jun;18(6):e13 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13345)
Background: Influenza viruses can cause zoonotic infections that pose public health risks. Surveillance of influenza A and B viruses is conducted globally; however, information on influenza C and D viruses ...

Bordes L, Gerhards NM, Peters S, van Oort S, Roose. H5N1 clade 2.3.4.4b avian influenza viruses replicate in differentiated bovine airway epithelial cells cultured at air-liquid interface. J Gen Virol. 2024 Jun;105(6).  Abstract  
submitted by kickingbird at Jun, 27, 2024 from J Gen Virol. 2024 Jun;105(6) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
Highly pathogenic avian influenza (HPAI) H5N1 viruses are responsible for disease outbreaks in wild birds and poultry, resulting in devastating losses to the poultry sector. Since 2020, an increasing number ...

Tang J, Zou SM, Zhou JF, Gao RB, Xin L, Zeng XX, H. R229I substitution from oseltamivir induction in HA1 region significantly increased the fitness of a H7N9 virus bearing NA 292K. Emerg Microbes Infect. 2024 Jun 26:2373314.  Abstract  
submitted by kickingbird at Jun, 27, 2024 from Emerg Microbes Infect. 2024 Jun 26:2373314 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
The proportion of human isolates with reduced neuraminidase inhibitors (NAIs) susceptibility in highly pathogenic avian influenza (HPAI) H7N9 virus was as high as 13%. These drug-resistant strains showed ...

Zhang X, Zhang Y, Wei F. Research progress on the nonstructural protein 1 (NS1) of influenza a virus. Virulence. 2024 Dec;15(1):2359470.  Abstract  
submitted by kickingbird at Jun, 27, 2024 from Virulence. 2024 Dec;15(1):2359470 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2024.2)
Influenza A virus (IAV) is the leading cause of highly contagious respiratory infections, which poses a serious threat to public health. The non-structural protein 1 (NS1) is encoded by segment 8 of IAV ...

Chatzilena A, Hyams C, Challen R, Marlow R, King J. Winter 2022-23 influenza vaccine effectiveness against influenza-related hospitalised aLRTD: A test-negative, case-control study. Vaccine. 2024 Jun 24:S0264-410X(24)00713-8.  Abstract  
submitted by kickingbird at Jun, 27, 2024 from Vaccine. 2024 Jun 24:S0264-410X(24)00713-8 (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
BackgroundInfluenza activity in the UK started early during the winter 2022–23 season, with most surveillance systems reporting high levels of hospitalisation, intensive care unit influenza admission and ...

Marina R. Good, etc.,al. [preprint]A single mutation in dairy cow-associated H5N1 viruses increases receptor binding breadth. https://doi.org/10.1101/2024.06.22.600211.  Abstract  
submitted by kickingbird at Jun, 25, 2024 from https://doi.org/10.1101/2024.06.22.600211 (via https://www.biorxiv.org/content/10.1101/2024.06.22.600211v1)
Clade 2.3.4.4b H5N1 is causing an unprecedented outbreak in dairy cows in the United States. To understand if recent H5N1 viruses are changing their receptor use, we screened recombinant hemagglutinin ...

Bonilla-Aldana DK, Calle-Hernández DM, Ulloque-Bad. Highly pathogenic avian influenza A(H5N1) in animals: A systematic review and meta-analysis. New Microbes New Infect. 2024 Jun 1;60-61:101439.  Abstract  
submitted by kickingbird at Jun, 25, 2024 from New Microbes New Infect. 2024 Jun 1;60-61:101439 (via https://www.sciencedirect.com/science/article/pii/S205229752)
Introduction: Avian influenza A H5N1 is a significant global public health threat. Although relevant, systematic reviews about its prevalence in animals are lacking.Methods: We performed a systematic literature ...

Le Sage V, Campbell AJ, Reed DS, Duprex WP, Lakdaw. Persistence of Influenza H5N1 and H1N1 Viruses in Unpasteurized Milk on Milking Unit Surfaces. Emerg Infect Dis. 2024 Jun 24;30(8).  Abstract  
submitted by kickingbird at Jun, 25, 2024 from Emerg Infect Dis. 2024 Jun 24;30(8) (via https://wwwnc.cdc.gov/eid/article/30/8/24-0775_article)
Examining the persistence of highly pathogenic avian influenza A(H5N1) from cattle and human influenza A(H1N1)pdm09 pandemic viruses in unpasteurized milk revealed that both remain infectious on milking ...

Liu T, Reiser WK, Tan TJC, Lv H, Rivera-Cardona J,. Natural variation in neuraminidase activity influences the evolutionary potential of the seasonal H1N1 lineage hemagglutinin. Virus Evol. 2024 Jun 19;10(1):veae046.  Abstract  
submitted by kickingbird at Jun, 25, 2024 from Virus Evol. 2024 Jun 19;10(1):veae046 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v)
The antigenic evolution of the influenza A virus hemagglutinin (HA) gene poses a major challenge for the development of vaccines capable of eliciting long-term protection. Prior efforts to understand the ...

Wu W, Alexander JS, Booth JL, Miller CA, Metcalf J. Influenza virus infection exacerbates gene expression related to neurocognitive dysfunction in brains of old mice. Immun Ageing. 2024 Jun 21;21(1):39.  Abstract  
submitted by kickingbird at Jun, 24, 2024 from Immun Ageing. 2024 Jun 21;21(1):39 (via https://immunityageing.biomedcentral.com/articles/10.1186/s1)
Background: Age > 65 years is a key risk factor for poor outcomes after human influenza infection. Specifically, in addition to respiratory disease, non-neurotropic influenza A virus (IAV) causes neuro-cognitive ...

Takadate Y, Mine J, Tsunekuni R, Sakuma S, Kumagai. Genetic diversity of H5N1 and H5N2 high pathogenicity avian influenza viruses isolated from poultry in Japan during the winter of 2022-2023. Virus Res. 2024 Jun 19:199425.  Abstract  
submitted by kickingbird at Jun, 23, 2024 from Virus Res. 2024 Jun 19:199425 (via https://pubmed.ncbi.nlm.nih.gov/38906223/)
High pathogenicity avian influenza viruses (HPAIVs) of the H5N1 and H5N2 subtypes were responsible for 84 HPAI outbreaks on poultry premises in Japan during October 2022-April 2023. The number of outbreaks ...

Dandachi I, Alrezaihi A, Amin D, AlRagi N, Alhatla. Molecular surveillance of influenza A virus in Saudi Arabia: whole-genome sequencing and metagenomic approaches. Microbiol Spectr. 2024 Jun 21:e0066524.  Abstract  
submitted by kickingbird at Jun, 22, 2024 from Microbiol Spectr. 2024 Jun 21:e0066524 (via https://journals.asm.org/doi/epub/10.1128/spectrum.00665-24)
Outbreaks of influenza A viruses are generally seasonal and cause annual epidemics worldwide. Due to their frequent reassortment and evolution, annual surveillance is of paramount importance to guide vaccine ...

Kareinen Lauri, Tammiranta Niina, Kauppinen Ari, Z. Highly pathogenic avian influenza A(H5N1) virus infections on fur farms connected to mass mortalities of black-headed gulls, Finland, July to October 2023. Euro Surveill. 2024;29(25):pii=2400063.  Abstract  
submitted by kickingbird at Jun, 21, 2024 from Euro Surveill. 2024;29(25):pii=2400063 (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
Highly pathogenic avian influenza (HPAI) has caused widespread mortality in both wild and domestic birds in Europe 2020–2023. In July 2023, HPAI A(H5N1) was detected on 27 fur farms in Finland. In total, ...

J Nuzzo, etc.,al. The United States Needs A Better Testing Playbook For Future Public Health Emergencies. https://doi.org/10.1377/hlthaff.2024.00038.  Abstract  
submitted by kickingbird at Jun, 21, 2024 from https://doi.org/10.1377/hlthaff.2024.00038 (via https://www.healthaffairs.org/doi/10.1377/hlthaff.2024.00038)
The absence of a comprehensive national playbook for developing and deploying testing has hindered the United States’ ability to rapidly suppress recent biological emergencies (for example, the COVID-19 ...

Wrotek, A., Jackowska, T. A noninferiority randomized open-label pilot study of 3- versus 7-day influenza postexposure prophylaxis with oseltamivir in hospitalized children. Sci Rep 14, 14192 (2024).  Abstract  
submitted by kickingbird at Jun, 21, 2024 from Sci Rep 14, 14192 (2024) (via https://www.nature.com/articles/s41598-024-65244-5)
Short influenza postexposure prophylaxis (PEP) showed high efficacy in adults, but studies in children are lacking. This randomized open-label pilot trial aimed to verify noninferiority of a 3- versus ...

Prosser, D.J., Kent, C.M., Sullivan, J.D. et al. Using an adaptive modeling framework to identify avian influenza spillover risk at the wild-domestic interface. Sci Rep 14, 14199 (2024).  Abstract  
submitted by kickingbird at Jun, 21, 2024 from Sci Rep 14, 14199 (2024) (via https://www.nature.com/articles/s41598-024-64912-w)
The wild to domestic bird interface is an important nexus for emergence and transmission of highly pathogenic avian influenza (HPAI) viruses. Although the recent incursion of HPAI H5N1 Clade 2.3.4.4b into ...

Sun Y, Wagatsuma K, Saito R, Sato I, Kawashima T,. Duration of fever in children infected with influenza A(H1N1)pdm09, A(H3N2) or B virus and treated with baloxavir marboxil, oseltamivir, laninamivir, or zanamivir in Japan during the 2012-2013 and 201. Antiviral Res. 2024 Jun 17:105938.  Abstract  
submitted by kickingbird at Jun, 20, 2024 from Antiviral Res. 2024 Jun 17:105938 (via https://www.sciencedirect.com/science/article/pii/S016635422)
We compared the duration of fever in children infected with A(H1N1)pdm09, A(H3N2), or influenza B viruses following treatment with baloxavir marboxil (baloxavir) or neuraminidase inhibitors (NAIs) (oseltamivir, ...

Adesola RO, Onoja BA, Adamu AM, Agbaje ST, Abdulaz. Molecular epidemiology and genetic evolution of avian influenza H5N1 subtype in Nigeria, 2006 to 2021. Virus Genes. 2024 Jun 19.  Abstract  
submitted by kickingbird at Jun, 20, 2024 from Virus Genes. 2024 Jun 19 (via https://link.springer.com/article/10.1007/s11262-024-02080-9)
Nigeria recorded one of the earliest outbreaks of the Highly Pathogenic Avian Influenza (HPAI) virus H5N1 in 2006, which spread to other African countries. In 2023, 18 countries reported outbreaks of H5N1 ...

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