Gazik NH, Holodniy M, Bayat V. Expanding Horizons: Host Range Evolution and Treatment Strategies for Highly Pathogenic Avian Influenza H5N1 and H7N9. Viruses. 2026; 18(1):54. Abstract
submitted by kickingbird at Dec, 31, 2025 from Viruses. 2026; 18(1):54 (via https://www.mdpi.com/1999-4915/18/1/54)
Avian influenza viruses (AIVs), including H5N1 and H7N9, from the Orthomyxoviridae family present substantial public health concerns. The predominant circulating clade 2.3.4.4b has demonstrated enhanced ... Alekseev A, Sobolev I, Sharshov K, Gulyaeva M, Kur. Pathobiology of Highly Pathogenic Avian Influenza A (H5N1 Clade 2.3.4.4b) Virus from Pinnipeds on Tyuleniy Island in the Sea of Okhotsk, Russia. Viruses. 2026; 18(1):51. Abstract
submitted by kickingbird at Dec, 31, 2025 from Viruses. 2026; 18(1):51 (via https://www.mdpi.com/1999-4915/18/1/51)
Highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b has recently emerged as a major threat to wildlife, agriculture, and public health due to its expanding host range and the increasing frequency ... Adams GC, Devlin JE, Klontz E, Laing RA, Branda JA. Development of a Combined Clinical and Research-Developed Testing Strategy for Highly Pathogenic Avian Influenza A Virus H5. Open Forum Infect Dis. 2025 Dec 10;13(1):ofaf744. Abstract
submitted by kickingbird at Dec, 30, 2025 from Open Forum Infect Dis. 2025 Dec 10;13(1):ofaf744 (via https://academic.oup.com/ofid/article/13/1/ofaf744/8376911)
Highly pathogenic avian influenza A (H5) virus continues to spread in animals with ongoing concern for potential human transmission. We describe an adaptable H5 screening approach that integrates clinical ... Avkan I, Gokool S, Smith LE, Clapp G, Cox R, Thoma. Quantifying H5N1 outbreak potential and control effectiveness in high-risk agricultural populations. PLOS Glob Public Health. 2025 Dec 29;5(12):e000546. Abstract
submitted by kickingbird at Dec, 30, 2025 from PLOS Glob Public Health. 2025 Dec 29;5(12):e000546 (via https://journals.plos.org/globalpublichealth/article?id=10.1)
Avian influenza is a global public health threat. Since 2021, the ongoing H5N1 panzootic has brought a major shift in H5Nx epidemiology, including unprecedented spread, wide host range and lack of seasonality. ... Tian C, Feng L, Zhou X, Huang K, Wang F, Luo R, Me. A Portable One-Tube Assay Integrating RT-RPA and CRISPR/Cas12a for Rapid Visual Detection of Eurasian Avian-like H1N1 Swine Influenza Virus in the Field. Viruses. 2026; 18(1):47. Abstract
submitted by kickingbird at Dec, 29, 2025 from Viruses. 2026; 18(1):47 (via https://www.mdpi.com/1999-4915/18/1/47)
The widespread circulation of Eurasian avian-like H1N1 (EA H1N1) swine influenza virus poses significant zoonotic and pandemic risks worldwide. However, current diagnostic methods are difficult to deploy ... Yuwen Luo, etc.,al. Impact of viral Ribonucleoprotein Complex Genetic Stability on Pathogenicity in H9N2 and H6N2 Avian Influenza Viruses. Developmental & Comparative Immunology. Abstract
submitted by kickingbird at Dec, 28, 2025 from Developmental & Comparative Immunology (via https://www.sciencedirect.com/science/article/abs/pii/S01453)
China has a great demand for poultry, while avian influenza (AI) remains widespread and exhibits high instability, posing a persistent challenge to the poultry industry. Elucidating the genetic stability ... Harrell T.L., Shwani A., Suarez D.L. The Impact of Acids, pH, and Incubation Time on Avian Influenza Virus Persistence in Raw Milk. Food Microbiology. Abstract
submitted by kickingbird at Dec, 28, 2025 from Food Microbiology (via https://www.sciencedirect.com/science/article/abs/pii/S07400)
In March 2024, highly pathogenic avian influenza virus (HPAIV) clade 2.3.4.4.b H5N1 was detected in dairy cattle. Since detection, the virus has spread across 17 states, infecting more than 1000 dairy ... Ane Marie Anderson, etc.,al. DNA vaccines targeting hemagglutinin from 18 subtypes of influenza A virus to antigen presenting cells confer broad protection. Molecular Therapy Nucleic Acids. Abstract
submitted by kickingbird at Dec, 28, 2025 from Molecular Therapy Nucleic Acids (via https://www.sciencedirect.com/science/article/pii/S216225312)
Novel vaccines that confer broad protection against influenza A viruses (IAV) are urgently needed. Hemagglutinin (HA) is the major influenza antigen targeted by protective immune responses. We have here ... Zhu, T., Zhu, M., Lu, F. et al. Pre-activation timing determines influenza severity and viral pathogenicity via STING Inhibition. Sci Rep 15, 44501 (2025). Abstract
submitted by kickingbird at Dec, 28, 2025 from Sci Rep 15, 44501 (2025) (via https://www.nature.com/articles/s41598-025-28063-w)
Severe influenza is frequently associated with bacterial or viral co-infections. Although immune-mediated mechanisms have been extensively investigated, the cell-intrinsic responses of respiratory epithelial ... Yang G, Chen P-L, Rovito SW, Minari K, Writt HN, D. Resistance Mutations to Broadly Neutralizing Antibodies Destabilize Hemagglutinin and Attenuate H1N1 Influenza Virus. Viruses. 2026; 18(1):32. Abstract
submitted by kickingbird at Dec, 25, 2025 from Viruses. 2026; 18(1):32 (via https://www.mdpi.com/1999-4915/18/1/32)
Because antigenic drift primarily generates amino-acid changes in the membrane-distal hemagglutinin (HA) head, broadly neutralizing antibodies (bNAbs) are being developed to target conserved epitopes in ... Panova, A.S., Gudymo, A.S., Kolosova, N.P. et al. Genotype A3 influenza A(H5N1) isolated from fur seals shows high virulence in mammals, but not airborne transmission. Sci Rep 15, 44463 (2025). Abstract
submitted by kickingbird at Dec, 25, 2025 from Sci Rep 15, 44463 (2025) (via https://link.springer.com/article/10.1038/s41598-025-28032-3)
The global spread of highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b viruses has recently extended to include diverse mammalian species, raising new concerns about pandemic risk. In 2023, this ... Mengdi Guan, etc.,al. Genetic diversity of H13 avian influenza viruses in migratory shorebirds in eastern China. Journal of Integrative Agriculture. Abstract
submitted by kickingbird at Dec, 25, 2025 from Journal of Integrative Agriculture (via https://www.sciencedirect.com/science/article/pii/S209531192)
Highlights1.Twenty one H13 subtype avian influenza viruses were isolated from 50016 samples in migratory birds during 2017 to 2024 in Shandong Province, China2.The H13 viruses were mainly harbored by shorebirds ... Epidemic and Pandemic Preparedness and Prevention. Stockpiling of medical countermeasures for pandemic influenza: considerations brief. WHO. Abstract
submitted by kickingbird at Dec, 24, 2025 from WHO (via https://www.who.int/publications/i/item/9789240117860)
This document provides a comprehensive, risk-informed framework to support countries in assessing, designing, and managing medical countermeasure (MCM) stockpiles for pandemic influenza and related respiratory ... Epidemic and Pandemic Preparedness and Prevention. Planning for national allocations of pandemic influenza medical countermeasures: considerations brief. WHO. Abstract
submitted by kickingbird at Dec, 24, 2025 from WHO (via https://www.who.int/publications/i/item/9789240117884)
This document presents comprehensive, ethics-based considerations to guide national decisions on allocating pandemic products such as vaccines, therapeutics, and diagnostics. Drawing on lessons from past ... Alvin Crespo-Bellido, etc.,al. [preprint]Emergence of D1.1 reassortant H5N1 avian influenza viruses in North America. https://doi.org/10.64898/2025.12.19.695329. Abstract
submitted by kickingbird at Dec, 24, 2025 from https://doi.org/10.64898/2025.12.19.695329 (via https://www.biorxiv.org/content/10.64898/2025.12.19.695329v1)
Since 2021, highly pathogenic avian influenza viruses (HPAIV) belonging to H5N1 clade 2.3.4.4b have caused high mortality in North American wild birds and poultry. In 2025, a new D1.1 genotype caused two ... Shen M, Yu J, Fu B, Yu C, Cui C, Chen S, et al. Influenza D Virus in Black Donkeys, Northern China. Emerg Infect Dis. 2025 Dec. Abstract
submitted by kickingbird at Dec, 24, 2025 from Emerg Infect Dis. 2025 Dec (via https://wwwnc.cdc.gov/eid/article/31/12/25-0666_article)
Influenza D virus (IDV) is prevalent in cattle in China, and a risk for spillover to other species exists. We detected IDV antibodies in 6/315 of black donkeys in northern China, suggesting cattle-to-donkey ... Hatta Y, De La Cruz J, Murray T, Hiatt B, Jang Y,. Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Poultry Farm Workers, Washington, USA, 2024. Emerg Infect Dis. 2025 Dec. Abstract
submitted by kickingbird at Dec, 24, 2025 from Emerg Infect Dis. 2025 Dec (via https://wwwnc.cdc.gov/eid/article/31/12/25-1118_article)
Poultry workers in Washington, USA, were infected with highly pathogenic avian influenza A(H5N1) virus and recovered. The viruses were clade 2.3.4.4b genotype D1.1, closely related to viruses causing poultry ... Song Y, Yan A, Song S, Gong H, Chen L, Fu B, Zhang. Phylogenetic Analyses and Biological Characterization of H9N2 Avian Influenza Virus Isolated from Chickens in China from 2022 to 2023. Microorganisms. 2026; 14(1):37. Abstract
submitted by kickingbird at Dec, 24, 2025 from Microorganisms. 2026; 14(1):37 (via https://www.mdpi.com/2076-2607/14/1/37)
The continued diversification of the H9N2 avian influenza virus (AIV) into multiple antigenically and phylogenetically distinct lineages is promoting the emergence of strains with pandemic potential. Constant ... Schmierer J, Lutz M, Takimoto T. 0. Enhanced genome replication activity of pandemic H1N1 influenza A virus through PA mutations. J Virol 0:e01391-25. Abstract
submitted by kickingbird at Dec, 24, 2025 from J Virol 0:e01391-25 (via https://journals.asm.org/doi/10.1128/jvi.01391-25)
The 2009 pandemic H1N1 (pH1N1) influenza A virus (IAV) is a reassortant virus with two polymerase components, PA and PB2, originating from avian IAV. Avian IAV polymerase does not function efficiently ... Jeffery D. Sullivan, etc.,al. Rapid increase in antibodies to influenza A virus H5 and N1 in Lesser Scaup (Aythya affinis) following the introduction of 2.3.4.4b H5N1 into North America. Canadian Journal of Microbiology. Abstract
submitted by kickingbird at Dec, 24, 2025 from Canadian Journal of Microbiology (via https://www.sciencedirect.com/org/science/article/pii/S00084)
Clade 2.3.4.4b Eurasian-origin H5N1 entered North America in late 2021 and spread across the continent. While studies have characterized the antibody response mounted by dabbling ducks following exposure, ... 9808 items, 20/Page, Page[9/491][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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