Bai Y, Lian P, Li J, Zhang Z, Qiao J. The active GLP-1 analogue liraglutide alleviates H9N2 influenza virus-induced acute lung injury in mice. Microb Pathog. 2020 Dec 4:104645. Abstract
submitted by kickingbird at Dec, 9, 2020 from Microb Pathog. 2020 Dec 4:104645 (via https://www.sciencedirect.com/science/article/pii/S088240102)
Influenza virus is responsible for significant morbidity and mortality worldwide. Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) is the major cause of death in influenza virus infected ...
Huang J, Huang N, Fan M, Zhao L, Luo Y, Ding P, Ti. Hemagglutinin stalk-based monoclonal antibody elicits broadly reactivity against group 1 influenza A virus. Virol J. 2020 Dec 7;17(1):191. Abstract
submitted by kickingbird at Dec, 9, 2020 from Virol J. 2020 Dec 7;17(1):191 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: Influenza virus remains a continuous and severe threat to public health worldwide, and its prevention and treatment have always been a major international issue. Because of its ability to evade ...
van de Wall S, Badovinac VP, Harty JT. Influenza-Specific Lung-Resident Memory CD8 + T Cells. Cold Spring Harb Perspect Biol. 2020 Dec 7:a037978. Abstract
submitted by kickingbird at Dec, 9, 2020 from Cold Spring Harb Perspect Biol. 2020 Dec 7:a037978 (via https://cshperspectives.cshlp.org/content/early/2020/12/07/c)
Despite the availability of seasonal vaccines, influenza A (IAV) prevails as a leading cause of respiratory infection worldwide. Current vaccination efforts aim at increasing protection against heterologous ...
Nachbagauer R, Feser J, Naficy A, Bernstein DI, Gu. A chimeric hemagglutinin-based universal influenza virus vaccine approach induces broad and long-lasting immunity in a randomized, placebo-controlled phase I trial. Nat Med. 2020 Dec 7. Abstract
submitted by kickingbird at Dec, 9, 2020 from Nat Med. 2020 Dec 7 (via https://www.nature.com/articles/s41591-020-1118-7)
Seasonal influenza viruses constantly change through antigenic drift and the emergence of pandemic influenza viruses through antigenic shift is unpredictable. Conventional influenza virus vaccines induce ...
Potter BI, Kondor R, Hadfield J, Huddleston J, Bar. Evolution and rapid spread of a reassortant A(H3N2) virus that predominated the 2017~2018 influenza season. Virus Evol. 2019 Dec 4;5(2):vez046. Abstract
submitted by kickingbird at Dec, 8, 2020 from Virus Evol. 2019 Dec 4;5(2):vez046 (via https://academic.oup.com/ve/article/5/2/vez046/5651259)
The 2017-2018 North American influenza season caused more hospitalizations and deaths than any year since the 2009 H1N1 pandemic. The majority of recorded influenza infections were caused by A(H3N2) viruses, ...
Liu Y, Fu C, Lu G, Luo J, Ye S, Ou J, Wang X, Xu H. Comparison of Pathogenicity of Different Infectious Doses of H3N2 Canine Influenza Virus in Dogs. Front Vet Sci. 2020 Nov 13;7:580301. Abstract
submitted by kickingbird at Dec, 8, 2020 from Front Vet Sci. 2020 Nov 13;7:580301 (via https://www.frontiersin.org/articles/10.3389/fvets.2020.5803)
The canine influenza virus (CIV) outbreaks have raised concerns as they pose a threat to the health of dogs. The successful construction of a canine influenza (CI) infection model is essential to study ...
Kaplan BS, Falkenberg S, Dassanayake R, Neill J, V. Virus Strain Influenced the Interspecies Transmission of Influenza D Virus Between Calves and Pigs. Transbound Emerg Dis. 2020 Dec 1. Abstract
submitted by kickingbird at Dec, 2, 2020 from Transbound Emerg Dis. 2020 Dec 1 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.13943)
Influenza D viruses (IDV) belong to a new genus in the family Orthomyxoviridae. IDV is the etiologic agent of acute, mild respiratory disease in ungulate species with agricultural importance (cattle, pigs, ...
Howland RE, Cowan NR, Wang SS, Moss ML, Glied S. Public transportation and transmission of viral respiratory disease: Evidence from influenza deaths in 121 cities in the United States. PLoS One. 2020 Dec 1;15(12):e0242990. Abstract
submitted by kickingbird at Dec, 2, 2020 from PLoS One. 2020 Dec 1;15(12):e0242990 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
One important concern around the spread of respiratory infectious diseases has been the contribution of public transportation, a space where people are in close contact with one another and with high-use ...
Caddy SL, Vaysburd M, Papa G, Wing M, O´Conn. Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity. EMBO J. 2020 Dec 1:e106228. Abstract
submitted by kickingbird at Dec, 2, 2020 from EMBO J. 2020 Dec 1:e106228 (via https://www.embopress.org/doi/full/10.15252/embj.2020106228)
Nucleoprotein (N) is an immunodominant antigen in many enveloped virus infections. While the diagnostic value of anti-N antibodies is clear, their role in immunity is not. This is because while they are ...
Bashashati M, Chung DH, Fallah Mehrabadi MH, Lee. Evolution of H9N2 avian influenza viruses in Iran, 2017~2019. Transbound Emerg Dis. 2020 Dec 1. Abstract
submitted by kickingbird at Dec, 2, 2020 from Transbound Emerg Dis. 2020 Dec 1 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.13944)
Since its first detection in 1998, avian influenza virus (AIV) subtype H9N2 has been enzootic in Iran. To better understand the evolutionary history of H9N2 viruses in Iran, we sequenced 15 currently circulating ...
Powell JD, Abente EJ, Chang J, Souza CK, Rajao DS,. Characterization of contemporary 2010.1 H3N2 swine influenza A viruses circulating in United States pigs. Virology. 2020 Nov 21;553:94-101. Abstract
submitted by kickingbird at Dec, 1, 2020 from Virology. 2020 Nov 21;553:94-101 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
In 2012, swine influenza surveillance detected a novel reassorted influenza A virus (IAV) strain containing human-seasonal hemagglutinin (HA) and neuraminidase (NA). Subsequently, these viruses reassorted, ...
Wang Y, Zhong W, Salam A, Tarning J, Zhan Q, Huang. Phase 2a, open-label, dose-escalating, multi-center pharmacokinetic study of favipiravir (T-705) in combination with oseltamivir in patients with severe influenza. EBioMedicine. 2020 Nov 21;62:103125. Abstract
submitted by kickingbird at Nov, 26, 2020 from EBioMedicine. 2020 Nov 21;62:103125 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: The pharmacokinetics and appropriate dose regimens of favipiravir are unknown in hospitalized influenza patients; such data are also needed to determine dosage selection for favipiravir trials ...
Li X, Liang Z, Gan J, Lu L.. Epidemic situation of the complex seasonality of imported Influenza A and B virus transmission in Guangxi ports of China. Turk J Med Sci. 2020 Nov 25. Abstract
submitted by kickingbird at Nov, 26, 2020 from Turk J Med Sci. 2020 Nov 25 (via https://pubmed.ncbi.nlm.nih.gov/33237658/)
Background/aim: Analysis of the characteristics of influenza virus in imported cases in Guangxi Province of China.Methods: Throat swabs of imported cases with influenza-like symptoms were detected by real-time ...
Zhu G, Kang M, Wei X, Tang T, Liu T, Xiao J, Song. Different intervention strategies toward live poultry markets against avian influenza A (H7N9) virus: model-based assessment. Environ Res. 2020 Nov 18:110465. Abstract
submitted by kickingbird at Nov, 24, 2020 from Environ Res. 2020 Nov 18:110465 (via https://www.sciencedirect.com/science/article/abs/pii/S00139)
Background: Different interventions targeting live poultry markets (LPMs) are applied in China for controlling avian influenza A (H7N9), including LPM closure and "1110" policy (i.e., daily cleaning, weekly ...
Qian Z, Shou-Yu G, Feng-Xia Z, Peng Y, Wen-Jian S,. Molecular characteristics of H9N2 influenza viruses isolated from farmed raccoon dogs and arctic foxes in China. Res Vet Sci. 2020 Nov 14:S0034-5288(20)31073-0. Abstract
submitted by kickingbird at Nov, 24, 2020 from Res Vet Sci. 2020 Nov 14:S0034-5288(20)31073-0 (via https://www.sciencedirect.com/science/article/abs/pii/S00345)
In this study, eight H9N2 IAVs were isolated from infected diseased, farmed raccoon dogs and arctic foxes. Eight genes shared 98.6%-100% identity among the isolates possessing a PSRSSR/GL motif at the ...
Qi Y, Wang H, Guo W, Liu C, Zhao L, Gu Y, Li S, Ch. Surveillance of multiple subtype specific antibodies against avian influenza viruses among egg yolk in wild ducks from northeast China, 2017~2019. Microb Pathog. 2020 Nov 18:104618. Abstract
submitted by kickingbird at Nov, 24, 2020 from Microb Pathog. 2020 Nov 18:104618 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
Over the past decade, various avian influenza viruses have been isolated from wild ducks found in the northeast of China. To monitor the prevalence of multiple subtype specific AIVs antibodies, 1705 wild ...
Carrique L, Fan H, Walker AP, Keown JR, Sharps J,. Host ANP32A mediates the assembly of the influenza virus replicase. Nature. 2020 Nov 18. Abstract
submitted by kickingbird at Nov, 22, 2020 from Nature. 2020 Nov 18 (via https://www.nature.com/articles/s41586-020-2927-z)
Aquatic birds represent a vast reservoir from which new pandemic influenza A viruses can emerge1. Influenza viruses contain a negative-sense segmented RNA genome that is transcribed and replicated by the ...
Chung DH, Gomez DR, Vargas JM, Amador BL, Torchett. Low Pathogenicity Avian Influenza (H5N2) Viruses, Dominican Republic. Emerg Infect Dis. 2020 Dec;26(12):3094-3096. Abstract
submitted by kickingbird at Nov, 22, 2020 from Emerg Infect Dis. 2020 Dec;26(12):3094-3096 (via https://wwwnc.cdc.gov/eid/article/26/12/20-0268_article)
Low pathogenicity avian influenza (H5N2) virus was detected in poultry in the Dominican Republic in 2007 and re-emerged in 2017. Whole-genome sequencing and phylogenetic analysis show introduction of an ...
Bravo-Vasquez N, Yao J, Jimenez-Bluhm P, Meliopoul. Equine-Like H3 Avian Influenza Viruses in Wild Birds, Chile. Emerg Infect Dis. 2020 Dec;26(12):2887-2898. Abstract
submitted by kickingbird at Nov, 22, 2020 from Emerg Infect Dis. 2020 Dec;26(12):2887-2898 (via https://wwwnc.cdc.gov/eid/article/26/12/20-2063_article)
Since their discovery in the United States in 1963, outbreaks of infection with equine influenza virus (H3N8) have been associated with serious respiratory disease in horses worldwide. Genomic analysis ...
Jiang Y, Ye Z, Chen D, Shu Y. Dual influenza and pneumococcal vaccination was associated with lower short-term risks of all-cause and acute respiratory hospitalizations among the elderly in Shenzhen, China: a retrospective cohort. Emerg Microbes Infect . 2020 Nov 20;1-0. Abstract
submitted by kickingbird at Nov, 22, 2020 from Emerg Microbes Infect . 2020 Nov 20;1-0 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2020.1)
Objectives The present study aimed to evaluate the real-world effectiveness of receiving both influenza and pneumococcal vaccines among Chinese elderly, the evidence on which has been sparse by far. Methods ...
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