Lalueza A, et al. Influence of viral load in the outcome of hospitalized patients with influenza virus infection. Eur J Clin Microbiol Infect Dis. 2019 Feb 28.. Abstract
submitted by kickingbird at Mar, 3, 2019 from Eur J Clin Microbiol Infect Dis. 2019 Feb 28. (via https://link.springer.com/article/10.1007%2Fs10096-019-03514)
The role of viral load in the outcome of patients requiring hospital admission due to influenza is not well established. We aim to assess if there is an association between the viral load and the outcome ...
Shepardson K, et al. A Novel Role for PDZ-Binding Motif of Influenza A Virus Nonstructural Protein 1 in Regulation of Host Susceptibility to Postinfluenza Bacterial Superinfections. Viral Immunol. 2019 Mar 1.. Abstract
submitted by kickingbird at Mar, 3, 2019 from Viral Immunol. 2019 Mar 1. (via https://www.liebertpub.com/doi/10.1089/vim.2018.0118)
Influenza A viruses (IAVs) have multiple mechanisms for altering the host immune response to aid in virus survival and propagation. While both type I and II interferons (IFNs) have been associated with ...
Hasan M, et al. Reverse vaccinology approach to design a novel multi-epitope subunit vaccine against avian influenza A (H7N9) virus. Microb Pathog. 2019 Feb 26. Abstract
submitted by kickingbird at Mar, 3, 2019 from Microb Pathog. 2019 Feb 26 (via https://www.sciencedirect.com/science/article/pii/S088240101)
H7N9, a novel strain of avian origin influenza was the first recorded incidence where a human was transited by a N9 type influenza virus. Effective vaccination against influenza A (H7N9) is a major concern, ...
Pei S, Cane MA, Shaman J. Predictability in process-based ensemble forecast of influenza. PLoS Comput Biol. 2019 Feb 28;15(2):e1006783. Abstract
submitted by kickingbird at Mar, 2, 2019 from PLoS Comput Biol. 2019 Feb 28;15(2):e1006783 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Process-based models have been used to simulate and forecast a number of nonlinear dynamical systems, including influenza and other infectious diseases. In this work, we evaluate the effects of model initial ...
Naguib MM, et al. Avian influenza viruses at the wild-domestic bird interface in Egypt. Infect Ecol Epidemiol. 2019 Feb 20;9(1):1575687.. Abstract
submitted by kickingbird at Mar, 1, 2019 from Infect Ecol Epidemiol. 2019 Feb 20;9(1):1575687. (via https://www.tandfonline.com/doi/full/10.1080/20008686.2019.1)
Wild birds of the orders Anseriformes (mainly ducks, geese and swans) and Charadriiformes (mainly gulls, terns and waders) constitute the natural reservoir for low pathogenic avian influenza (LPAI) viruses. ...
Zeng H, et al. Tropism and Infectivity of a Seasonal A(H1N1) and a Highly Pathogenic Avian A(H5N1) Influenza Virus in Primary Differentiated Ferret Nasal Epithelial Cell Cultures. J Virol. 2019 Feb 27.. Abstract
submitted by kickingbird at Mar, 1, 2019 from J Virol. 2019 Feb 27. (via https://jvi.asm.org/content/early/2019/02/22/JVI.00080-19)
Ferrets represent an invaluable animal model to study influenza virus pathogenesis and transmission. To further characterize this model, we developed a differentiated primary ferret nasal epithelial cell ...
Tang YS, Lo CY, Mok CK, Chan PK, Shaw PC. The extended C-terminal region of influenza C nucleoprotein is important for nuclear import and RNP activity. J Virol. 2019 Feb 27. Abstract
submitted by kickingbird at Mar, 1, 2019 from J Virol. 2019 Feb 27 (via https://jvi.asm.org/content/early/2019/02/22/JVI.02048-18)
The influenza C virus (ICV) is a human pathogenic agent and the infections are frequently identified in children. Compared to influenza A and B viruses, the nucleoprotein of ICV (NPC) has an extended C-terminal ...
Lu Y, et al. In Vivo Characterization of Avian Influenza A (H5N1) and (H7N9) Viruses Isolated from Canadian Travelers. Viruses. 2019 Feb 23;11(2).. Abstract
submitted by kickingbird at Mar, 1, 2019 from Viruses. 2019 Feb 23;11(2). (via https://www.mdpi.com/1999-4915/11/2/193)
Highly pathogenic avian influenza (HPAI) H5N1 and low pathogenic avian influenza (LPAI) H7N9 viruses pose a severe threat to public health through zoonotic infection, causing severe respiratory disease ...
Blanco-Lobo P, Nogales A, Rodríguez L, etc al. Novel Approaches for The Development of Live Attenuated Influenza Vaccines. Viruses. 2019 Feb 22;11(2).. Abstract
submitted by kickingbird at Mar, 1, 2019 from Viruses. 2019 Feb 22;11(2). (via https://www.mdpi.com/1999-4915/11/2/190)
Influenza virus still represents a considerable threat to global public health, despite the advances in the development and wide use of influenza vaccines. Vaccination with traditional inactivate influenza ...
Li Z, Fu J, Lin G, Jiang D. Spatiotemporal Variation and Hotspot Detection of the Avian Influenza A(H7N9) Virus in China, 2013~2017. Int J Environ Res Public Health. 2019 Feb 22;16(4). Abstract
submitted by kickingbird at Mar, 1, 2019 from Int J Environ Res Public Health. 2019 Feb 22;16(4) (via https://www.mdpi.com/1660-4601/16/4/648)
This study aims to describe the spatial and temporal characteristics of human infections with H7N9 virus in China using data from 19 February 2013 to 30 September 2017 extracted from Centre for Health ...
Kissling E, et al. Interim 2018/19 influenza vaccine effectiveness: six European studies, October 2018 to January 2019. Euro Surveill. 2019 Feb;24(8).. Abstract
submitted by kickingbird at Feb, 28, 2019 from Euro Surveill. 2019 Feb;24(8). (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
Influenza A(H1N1)pdm09 and A(H3N2) viruses both circulated in Europe in October 2018-January 2019. Interim results from six studies indicate that 2018/19 influenza vaccine effectiveness (VE) estimates ...
Corbett KS, et al. Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages. MBio. 2019 Feb 26;10(1).. Abstract
submitted by kickingbird at Feb, 28, 2019 from MBio. 2019 Feb 26;10(1). (via https://mbio.asm.org/content/10/1/e02810-18)
Influenza vaccines targeting the highly conserved stem of the hemagglutinin (HA) surface glycoprotein have the potential to protect against pandemic and drifted seasonal influenza viruses not covered by ...
Kramer SC, Shaman J. Development and validation of influenza forecasting for 64 temperate and tropical countries. PLoS Comput Biol. 2019 Feb 27;15(2):e1006742.. Abstract
submitted by kickingbird at Feb, 28, 2019 from PLoS Comput Biol. 2019 Feb 27;15(2):e1006742. (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Accurate forecasts of influenza incidence can be used to inform medical and public health decision-making and response efforts. However, forecasting systems are uncommon in most countries, with a few notable ...
Farsakoglu Y, et al. Influenza Vaccination Induces NK-Cell-Mediated Type-II IFN Response that Regulates Humoral Immunity in an IL-6-Dependent Manner. Cell Rep. 2019 Feb 26;26(9):2307-2315.e5. Abstract
submitted by kickingbird at Feb, 28, 2019 from Cell Rep. 2019 Feb 26;26(9):2307-2315.e5 (via https://www.cell.com/cell-reports/fulltext/S2211-1247(19)301)
The role of natural killer (NK) cells in the immune response against vaccines is not fully understood. Here, we examine the function of infiltrated NK cells in the initiation of the inflammatory response ...
Klifa R, et al. Influenza vaccination among children with idiopathic nephrotic syndrome: an investigation of practices. BMC Nephrol. 2019 Feb 25;20(1):65.. Abstract
submitted by kickingbird at Feb, 27, 2019 from BMC Nephrol. 2019 Feb 25;20(1):65. (via https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882)
BACKGROUND: Annual influenza vaccination is recommended for all children with idiopathic nephrotic syndrome (INS) in France. Consequently, the Social Security automatically sends prescriptions to all patients ...
Rich HE, et al. Interferon Lambda Inhibits Bacterial Uptake During Influenza Super-Infection. Infect Immun. 2019 Feb 25. Abstract
submitted by kickingbird at Feb, 27, 2019 from Infect Immun. 2019 Feb 25 (via https://iai.asm.org/content/early/2019/02/22/IAI.00114-19)
Influenza kills 30-40,000 people each year in the United States, and causes ten times as many hospitalizations. A common complication of influenza is bacterial super-infection, which exacerbates morbidity ...
Jorquera PA, et al. Insights into the antigenic advancement of influenza A(H3N2) viruses, 2011~2018. Sci Rep. 2019 Feb 25;9(1):2676.. Abstract
submitted by kickingbird at Feb, 27, 2019 from Sci Rep. 2019 Feb 25;9(1):2676. (via https://www.nature.com/articles/s41598-019-39276-1)
Influenza A(H3N2) viruses evade human immunity primarily by acquiring antigenic changes in the haemagglutinin (HA). HA receptor-binding features of contemporary A(H3N2) viruses hinder traditional antigenic ...
Holzer B, Martini V, Edmans M, Tchilian E. T and B Cell Immune Responses to Influenza Viruses in Pigs. Front Immunol. 2019 Feb 5;10:98.. Abstract
submitted by kickingbird at Feb, 27, 2019 from Front Immunol. 2019 Feb 5;10:98. (via https://www.frontiersin.org/articles/10.3389/fimmu.2019.0009)
Influenza viruses are an ongoing threat to humans and are endemic in pigs, causing considerable economic losses to farmers. Pigs are also a source of new viruses potentially capable of initiating human ...
Worobey M, Cox J, Gill D. The origins of the great pandemic. Evol Med Public Health. 2019 Jan 21;2019(1):18-25. Abstract
submitted by kickingbird at Feb, 27, 2019 from Evol Med Public Health. 2019 Jan 21;2019(1):18-25 (via https://academic.oup.com/emph/article/2019/1/18/5298310)
The timing and location of the first cases of the 1918 influenza pandemic are still controversial, a century after the pandemic became widely recognized. Here, we critically review competing hypotheses ...
Abusrewil S, et al. Influenza surveillance in Middle East, North, East and South Africa: Report of the 8th MENA Influenza Stakeholders Network. Influenza Other Respir Viruses. 2019 Feb 22.. Abstract
submitted by kickingbird at Feb, 27, 2019 from Influenza Other Respir Viruses. 2019 Feb 22. (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12628)
The Middle-East and Africa Influenza Surveillance Network (MENA-ISN), established in 2014, includes 15 countries at present. Country representatives presented their influenza surveillance programmes, vaccine ...
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