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2020-3-31 19:05:34
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Babakazo P, et al. Evaluation of the influenza sentinel surveillance system in the Democratic Republic of Congo, 2012-2015. BMC Public Health. 2019 Dec 10;19(1):1652..  Abstract  
submitted by kickingbird at Dec, 15, 2019 from BMC Public Health. 2019 Dec 10;19(1):1652. (via https://bmcpublichealth.biomedcentral.com/articles/10.1186/s)
BACKGROUND: The World Health Organization recommends periodic evaluations of influenza surveillance systems to identify areas for improvement and provide evidence of data reliability for policymaking. ...

Zhu YL, et al. Reversible Parkinsonism caused by Influenza B-associated encephalitis affecting bilateral basal ganglia: A case report. CNS Neurosci Ther. 2019 Dec 10..  Abstract  
submitted by kickingbird at Dec, 15, 2019 from CNS Neurosci Ther. 2019 Dec 10. (via https://onlinelibrary.wiley.com/doi/full/10.1111/cns.13278)
Influenza viruses are important human pathogens that often cause respiratory tract infections, while neurological complications are rare.1 Secondary Parkinsonism following viral infections usually occur ...

Suttie A, et al. The evolution and genetic diversity of avian influenza A(H9N2) viruses in Cambodia, 2015-2016. PLoS One. 2019 Dec 9;14(12):e0225428..  Abstract  
submitted by kickingbird at Dec, 11, 2019 from PLoS One. 2019 Dec 9;14(12):e0225428. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Low pathogenic A(H9N2) subtype avian influenza viruses (AIVs) were originally detected in Cambodian poultry in 2013, and now circulate endemically. We sequenced and characterised 64 A(H9N2) AIVs detected ...

Suttie A, et al. Diversity of A(H5N1) clade 2.3.2.1c avian influenza viruses with evidence of reassortment in Cambodia, 2014-2016. PLoS One. 2019 Dec 9;14(12):e0226108..  Abstract  
submitted by kickingbird at Dec, 11, 2019 from PLoS One. 2019 Dec 9;14(12):e0226108. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
In Cambodia, highly pathogenic avian influenza A(H5N1) subtype viruses circulate endemically causing poultry outbreaks and zoonotic human cases. To investigate the genomic diversity and development of ...

Suehiro Sakaguchi, Junji Chida. Prion Protein is a Novel Modulator of Influenza: Potential Implications for Anti-Influenza Therapeutics. Curr. Issues Mol. Biol. (2020) 37: 21-32.  Abstract  
submitted by kickingbird at Dec, 11, 2019 from Curr. Issues Mol. Biol. (2020) 37: 21-32 (via https://www.caister.com/cimb/abstracts/v37/21.html)
Worldwide spread of influenza A virus (IAV) strains, which are resistant to currently available anti- influenza agents such as viral neuraminidase inhibitors, has encouraged identification of new target ...

Fatima U, et al. Equine Mx1 Restricts Influenza A Virus Replication by Targeting at Distinct Site of its Nucleoprotein. Viruses. 2019 Dec 2;11(12)..  Abstract  
submitted by kickingbird at Dec, 10, 2019 from Viruses. 2019 Dec 2;11(12). (via https://www.mdpi.com/1999-4915/11/12/1114)
Interferon-mediated host factors myxovirus (Mx) proteins are key features in regulating influenza A virus (IAV) infections. Viral polymerases are essential for viral replication. The Mx1 protein has been ...

Shehata MM, et al. A Recombinant Influenza A/H1N1 Carrying A Short Immunogenic Peptide of MERS-CoV as Bivalent Vaccine in BALB/c Mice. Pathogens. 2019 Dec 2;8(4)..  Abstract  
submitted by kickingbird at Dec, 10, 2019 from Pathogens. 2019 Dec 2;8(4). (via https://www.mdpi.com/2076-0817/8/4/281)
Middle East Respiratory Syndrome Coronavirus (MERS-CoV) became a global human health threat since its first documentation in humans in 2012. An efficient vaccine for the prophylaxis of humans in hotspots ...

Van Poelvoorde LAE, Saelens X, Thomas I, Roosen NH. Next-Generation Sequencing: An Eye-Opener for the Surveillance of Antiviral Resistance in Influenza. Trends Biotechnol. 2019 Dec.  Abstract  
submitted by kickingbird at Dec, 10, 2019 from Trends Biotechnol. 2019 Dec (via https://www.cell.com/trends/biotechnology/fulltext/S0167-779)
Next-generation sequencing (NGS) can enable a more effective response to a wide range of communicable disease threats, such as influenza, which is one of the leading causes of human morbidity and mortality ...

van de Sandt CE, et al. Challenging immunodominance of influenza-specific CD8+ T cell responses restricted by the risk-associated HLA-A*68:01 allomorph. Nat Commun. 2019 Dec 6;10(1):557.  Abstract  
submitted by kickingbird at Dec, 10, 2019 from Nat Commun. 2019 Dec 6;10(1):557 (via https://www.nature.com/articles/s41467-019-13346-4)
Although influenza viruses lead to severe illness in high-risk populations, host genetic factors associated with severe disease are largely unknown. As the HLA-A*68:01 allele can be linked to severe pandemic ...

Xu C, Shu Y. The heterogeneity of influenza seasonality by subtype and lineage in China. J Infect. 2019 Nov 29..  Abstract  
submitted by kickingbird at Dec, 8, 2019 from J Infect. 2019 Nov 29. (via https://www.journalofinfection.com/article/S0163-4453(19)303)
Recently, a notable pattern of synchrony of influenza A and B virus, and respiratory syncytial virus incidence peaks globally was reported in this journal. A previous study characterized seasonal pattern ...

Dellicour S, et al. Incorporating heterogeneous sampling probabilities in continuous phylogeographic inference - application to H5N1 spread in the Mekong region. Bioinformatics. 2019 Dec 2.  Abstract  
submitted by kickingbird at Dec, 8, 2019 from Bioinformatics. 2019 Dec 2 (via https://www.ncbi.nlm.nih.gov/pubmed/31790143)
MOTIVATION: The potentially low precision associated with the geographic origin of sampled sequences represents an important limitation for spatially-explicit (i.e. continuous) phylogeographic inference ...

Loh L, Koutsakos M, Kedzierska K, Hinks TSC. Influenza A Virus-Infected Lung Epithelial Cell Co-Culture with Human Peripheral Blood Mononuclear Cells. Methods Mol Biol. 2020;2098:141-147.  Abstract  
submitted by kickingbird at Dec, 8, 2019 from Methods Mol Biol. 2020;2098:141-147 (via https://www.ncbi.nlm.nih.gov/pubmed/31792820)
Sensing of influenza A virus (IAV) infection by pattern recognition receptors can occur by either direct infection of lung epithelial cells or uptake of virus-infected cells by innate cells such as dendritic ...

Njouom R, et al. Circulation of influenza virus from 2009 to 2018 in Cameroon: 10 years of surveillance data. PLoS One. 2019 Dec 3;14(12):e0225793..  Abstract  
submitted by kickingbird at Dec, 8, 2019 from PLoS One. 2019 Dec 3;14(12):e0225793. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Since the recent emergence of several subtypes of influenza viruses with pandemic potentials, there has been growing interest on the control of this infection worldwide. This study aimed to describe the ...

Zhou Y, Li S, Bi S, Li N, Bi Y, Liu W, Wang B. Long-lasting protective immunity against H7N9 infection is induced by intramuscular or CpG-adjuvanted intranasal immunization with the split H7N9 vaccine. Int Immunopharmacol. 2019 Dec 2:106013..  Abstract  
submitted by kickingbird at Dec, 8, 2019 from Int Immunopharmacol. 2019 Dec 2:106013. (via https://www.sciencedirect.com/science/article/pii/S156757691)
There is an urgent need for efficient vaccines against the highly pathogenic avian influenza A viral strain H7N9. The duration and intensity of the immune response to H7N9 critically impacts the epidemiology ...

Pascua PNQ, et al. Influenza B viruses from different genetic backgrounds are variably impaired by neuraminidase inhibitor resistance-associated substitutions. Antiviral Res. 2019 Nov 29:104669..  Abstract  
submitted by kickingbird at Dec, 7, 2019 from Antiviral Res. 2019 Nov 29:104669. (via https://www.sciencedirect.com/science/article/pii/S016635421)
Identifying evolutionary routes to antiviral resistance among influenza viruses informs molecular-based resistance surveillance and clinical decisions. To improve antiviral management and understand whether ...

Imai M, et al. Influenza A variants with reduced susceptibility to baloxavir isolated from Japanese patients are fit and transmit through respiratory droplets. Nat Microbiol. 2019 Nov 25..  Abstract  
submitted by kickingbird at Dec, 7, 2019 from Nat Microbiol. 2019 Nov 25. (via https://www.nature.com/articles/s41564-019-0609-0)
Here we report the isolation of the influenza A/H1N1 2009 pandemic (A/H1N1pdm) and A/H3N2 viruses carrying an I38T mutation in the polymerase acidic protein-a mutation that confers reduced susceptibility ...

Bogdanow B, et al. The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant. Nat Commun. 2019 Dec 4;10(1):5518.  Abstract  
submitted by kickingbird at Dec, 7, 2019 from Nat Commun. 2019 Dec 4;10(1):5518 (via https://www.nature.com/articles/s41467-019-13520-8)
Pandemic influenza A virus (IAV) outbreaks occur when strains from animal reservoirs acquire the ability to infect and spread among humans. The molecular basis of this species barrier is incompletely understood. ...

Chiapponi C, et al. Detection of a New Genetic Cluster of Influenza D Virus in Italian Cattle. Viruses. 2019 Nov 30;11(12)..  Abstract  
submitted by kickingbird at Dec, 7, 2019 from Viruses. 2019 Nov 30;11(12). (via https://www.mdpi.com/1999-4915/11/12/1110)
Influenza D virus (IDV) has been increasingly reported all over the world. Cattle are considered the major viral reservoir. Based on the hemagglutinin-esterase (HEF) gene, three main genetic and antigenic ...

Zhong G, et al. Mutations in the NA-like protein of bat influenza H18N11 virus enhance virus replication in mammalian cells, mice, and ferrets. J Virol. 2019 Dec 4.  Abstract  
submitted by kickingbird at Dec, 7, 2019 from J Virol. 2019 Dec 4 (via https://jvi.asm.org/content/early/2019/11/28/JVI.01416-19)
To characterize bat influenza H18N11 virus, we propagated a reverse genetics-generated H18N11 virus in MDCK II cells and detected two adapting mutations in the neuraminidase (NA)-like protein (NA-F144C ...

Valesano AL, et al. Influenza B viruses exhibit lower within-host diversity than influenza A viruses in human hosts. J Virol. 2019 Dec 4.  Abstract  
submitted by kickingbird at Dec, 7, 2019 from J Virol. 2019 Dec 4 (via https://jvi.asm.org/content/early/2019/11/28/JVI.01710-19)
Influenza B virus undergoes seasonal antigenic drift more slowly than influenza A, but the reasons for this difference are unclear. While the evolutionary dynamics of influenza viruses play out globally, ...

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