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2024-7-17 17:28:21
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Siegers JY, Dhanasekaran V, Xie R, Deng YM, Patel. Genetic and Antigenic Characterization of an Influenza A(H3N2) Outbreak in Cambodia and the Greater Mekong Subregion during the COVID-19 Pandemic, 2020. J Virol. 2021 Sep 29:JVI0126721.  Abstract  
submitted by kickingbird at Sep, 30, 2021 from J Virol. 2021 Sep 29:JVI0126721 (via https://journals.asm.org/doi/10.1128/JVI.01267-21)
Introduction of non-pharmaceutical interventions to control COVID-19 in early 2020 coincided with a global decrease in active influenza circulation. However, between July and November 2020, an influenza ...

Nogales A, Villamayor L, Utrilla-Trigo S, Ortego J. Natural Selection of H5N1 Avian Influenza A Viruses with Increased PA-X and NS1 Shutoff Activity. Viruses. 2021 Sep 3;13(9):1760.  Abstract  
submitted by kickingbird at Sep, 29, 2021 from Viruses. 2021 Sep 3;13(9):1760 (via https://www.mdpi.com/1999-4915/13/9/1760)
Influenza A viruses (IAV) can infect a broad range of mammalian and avian species. However, the host innate immune system provides defenses that restrict IAV replication and infection. Likewise, IAV have ...

Sanogo IN, Kouakou C, Batawui K, Djegui F, Byaruga. Serological Surveillance of Influenza D Virus in Ruminants and Swine in West and East Africa, 2017-2020. Viruses. 2021 Sep 2;13(9):1749.  Abstract  
submitted by kickingbird at Sep, 29, 2021 from Viruses. 2021 Sep 2;13(9):1749 (via https://www.mdpi.com/1999-4915/13/9/1749)
Influenza D virus (IDV) was first isolated in 2011 in Oklahoma, USA from pigs presenting with influenza-like symptoms. IDV is known to mainly circulate in ruminants, especially cattle. In Africa, there ...

Kotani O, Suzuki Y, Saito S, Ainai A, Ueno A, Hemm. Structure-Guided Creation of an Anti-HA Stalk Antibody F11 Derivative That Neutralizes Both F11-Sensitive and -Resistant Influenza A(H1N1)pdm09 Viruses. Viruses. 2021 Aug 31;13(9):1733.  Abstract  
submitted by kickingbird at Sep, 29, 2021 from Viruses. 2021 Aug 31;13(9):1733 (via https://www.mdpi.com/1999-4915/13/9/1733)
The stalk domain of influenza virus envelope glycoprotein hemagglutinin (HA) constitutes the axis connecting the head and transmembrane domains, and plays pivotal roles in conformational rearrangements ...

Mytle N, Leyrer S, Inglefield JR, Harris AM, Hicke. Influenza Antigens NP and M2 Confer Cross Protection to BALB/c Mice against Lethal Challenge with H1N1, Pandemic H1N1 or H5N1 Influenza A Viruses. Viruses. 2021 Aug 27;13(9):1708.  Abstract  
submitted by kickingbird at Sep, 29, 2021 from Viruses. 2021 Aug 27;13(9):1708 (via https://www.mdpi.com/1999-4915/13/9/1708)
Influenza hemagglutinin (HA) is considered a major protective antigen of seasonal influenza vaccine but antigenic drift of HA necessitates annual immunizations using new circulating HA versions. Low variation ...

Baidya S, Nishimoto Y, Sato S, Shimada Y, Sakurai. Dual Effect of Organogermanium Compound THGP on RIG-I-Mediated Viral Sensing and Viral Replication during Influenza a Virus Infection. Viruses. 2021 Aug 24;13(9):1674.  Abstract  
submitted by kickingbird at Sep, 29, 2021 from Viruses. 2021 Aug 24;13(9):1674 (via https://www.mdpi.com/1999-4915/13/9/1674)
The interaction of viral nucleic acid with protein factors is a crucial process for initiating viral polymerase-mediated viral genome replication while activating pattern recognition receptor (PRR)-mediated ...

Zhao B, Li H, Cao S, Zhong W, Li B, Jia W, Ning Z. Negative Regulators of Inflammation Response to the Dynamic Expression of Cytokines in DF-1 and MDCK Cells Infected by Avian Influenza Viruses. Inflammation. 2021 Sep 28.  Abstract  
submitted by kickingbird at Sep, 29, 2021 from Inflammation. 2021 Sep 28 (via https://link.springer.com/article/10.1007%2Fs10753-021-01568)
The H5N1 and H9N2 avian influenza viruses (AIVs) seriously endanger the poultry industry and threaten human health. Characteristic inflammatory responses caused by H5N1 and H9N2 AIVs in birds and mammals ...

El Guerche-Séblain C, Rigoine De Fougerolles T, Sa. Comparison of influenza surveillance systems in Australia, China, Malaysia and expert recommendations for influenza control. BMC Public Health. 2021 Sep 26;21(1):1750.  Abstract  
submitted by kickingbird at Sep, 28, 2021 from BMC Public Health. 2021 Sep 26;21(1):1750 (via https://bmcpublichealth.biomedcentral.com/articles/10.1186/s)
Background: The Western Pacific Region (WPR) is exposed each year to seasonal influenza and is often the source of new influenza virus variants and novel pathogen emergence. National influenza surveillance ...

Shinde V, Cho I, Plested JS, Agrawal S, Fiske J, C. Comparison of the safety and immunogenicity of a novel Matrix-M-adjuvanted nanoparticle influenza vaccine with a quadrivalent seasonal influenza vaccine in older adults: a phase 3 randomised controlle. ancet Infect Dis. 2021 Sep 23:S1473-3099(21)00192-.  Abstract  
submitted by kickingbird at Sep, 28, 2021 from ancet Infect Dis. 2021 Sep 23:S1473-3099(21)00192- (via https://www.thelancet.com/journals/laninf/article/PIIS1473-3)
Background: Improved seasonal influenza vaccines for older adults that can induce broadly cross-reactive antibodies and enhanced T-cell responses, particularly against A H3N2 viruses, while avoiding egg-adaptive ...

Elsayed M, Arafa A, Abdelwahab S, Hashish A, Youss. Novel reassortant of H9N2 avian influenza viruses isolated from chickens and quails in Egypt. Vet World. 2021 Aug;14(8):2142-2149.  Abstract  
submitted by kickingbird at Sep, 28, 2021 from Vet World. 2021 Aug;14(8):2142-2149 (via http://www.veterinaryworld.org/Vol.14/August-2021/21.html)
Background and aim: Poultry infections with H9N2 avian influenza viruses (AIVs) are endemic in Egypt. This study determined the genetic changes in the sequences of H9N2 AIVs isolated from chicken and quails ...

Park G, Kim HO, Lim JW, Park C, Yeom M, Song D, Ha. Rapid detection of influenza A (H1N1) virus by conductive polymer-based nanoparticle via optical response to virus-specific binding. Nano Res. 2021 Sep 21:1-9.  Abstract  
submitted by kickingbird at Sep, 28, 2021 from Nano Res. 2021 Sep 21:1-9 (via https://link.springer.com/article/10.1007%2Fs12274-021-3772-)
A recurrent pandemic with unpredictable viral nature has implied the need for a rapid diagnostic technology to facilitate timely and appropriate countermeasures against viral infections. In this study, ...

Froggatt HM, Burke KN, Chaparian RR, Miranda HA, Z. Influenza A virus segments five and six can harbor artificial introns allowing expanded coding capacity. PLoS Pathog. 2021 Sep 27;17(9):e1009951.  Abstract  
submitted by kickingbird at Sep, 28, 2021 from PLoS Pathog. 2021 Sep 27;17(9):e1009951 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Influenza A viruses encode their genomes across eight, negative sense RNA segments. The six largest segments produce mRNA transcripts that do not generally splice; however, the two smallest segments are ...

Weekly U.S. Influenza Surveillance Report. US CDC Fluview: Novel Influenza A Virus A(H1N2)v_ possible h2h. US CDC.  Abstract  
submitted by kickingbird at Sep, 26, 2021 from US CDC (via https://www.cdc.gov/flu/weekly/index.htm)
One human infection with an influenza A(H1N2) variant (A(H1N2)v) virus was reported by Ohio. The patient is When an influenza virus that normally circulates in swine (but not people) is detected in a person, ...

Zhang RR, Yang X, Shi CW, Yu LJ, Lian YB, Huang HB. Improved pathogenicity of H9N2 subtype of avian influenza virus induced by mutations occurred after serial adaptations in mice. Microb Pathog. 2021 Sep 22:105204.  Abstract  
submitted by kickingbird at Sep, 26, 2021 from Microb Pathog. 2021 Sep 22:105204 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
H9N2 subtype, a low pathogenic avian influenza virus, is emerging as a major causative agent circulating poultry workplaces across China and other Asian countries. Increasing case number of interspecies ...

Wang T, Wei F, Liu L, Sun Y, Song J, Wang M, Yang. Recombinant HA1-ΔfliC enhances adherence to respiratory epithelial cells and promotes the superiorly protective immune responses against H9N2 influenza virus in chickens. et Microbiol. 2021 Sep 15;262:109238.  Abstract  
submitted by kickingbird at Sep, 26, 2021 from et Microbiol. 2021 Sep 15;262:109238 (via https://www.sciencedirect.com/science/article/pii/S037811352)
H9N2 subtype avian influenza virus (AIV) is an ongoing threat causing substantial loss to the poultry industry and thus necessitating the development of safe and effective vaccines against AIV. Given that ...

Yang F, Xiao Y, Liu F, Yao H, Wu N, Wu H. Molecular Characterization and Antigenic analysis of reassortant H9N2 subtype avian influenza viruses in Eastern China in 2016. Virus Res. 2021 Sep 21:198577..  Abstract  
submitted by kickingbird at Sep, 26, 2021 from Virus Res. 2021 Sep 21:198577. (via https://pubmed.ncbi.nlm.nih.gov/34560182/)
H9N2 avian influenza viruses (AIVs) can cause respiratory symptoms and decrease the egg production. Additionally, H9N2 AIVs can provide internal genes for reassortment with other subtypes. During the monitoring ...

West J, R?der J, Matrosovich T, Beicht J, Baumann. Characterization of changes in the hemagglutinin that accompanied the emergence of H3N2/1968 pandemic influenza viruses. PLoS Pathog. 2021 Sep 23;17(9):e1009566..  Abstract  
submitted by kickingbird at Sep, 26, 2021 from PLoS Pathog. 2021 Sep 23;17(9):e1009566. (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The hemagglutinin (HA) of A/H3N2 pandemic influenza viruses (IAVs) of 1968 differed from its inferred avian precursor by eight amino acid substitutions. To determine their phenotypic effects, we studied ...

Marsh CK, Sheppeard V, Tobin S, Gilmour R, Andrews. Drivers of the summer influenza epidemic in New South Wales, 2018-19. Med J Aust. 2021 Sep 21.  Abstract  
submitted by kickingbird at Sep, 23, 2021 from Med J Aust. 2021 Sep 21 (via https://onlinelibrary.wiley.com/doi/10.5694/mja2.51266)
Objectives: To assess the extent to which the 2018-19 New South Wales summer influenza epidemic was associated with overseas or domestic travel and with seasonal influenza vaccination status.Design, setting: ...

Kohli MA, Maschio M, Mould-Quevedo JF, Drummond M,. The cost-effectiveness of an adjuvanted quadrivalent influenza vaccine in the United Kingdom. Hum Vaccin Immunother. 2021 Sep 22:1-8.  Abstract  
submitted by kickingbird at Sep, 23, 2021 from Hum Vaccin Immunother. 2021 Sep 22:1-8 (via https://www.tandfonline.com/doi/full/10.1080/21645515.2021.1)
In the United Kingdom (UK), both the MF59-adjuvanted quadrivalent influenza vaccine (aQIV) and the high-dose QIV (QIV-HD) are preferred for persons aged 65 years and older but only aQIV is reimbursed by ...

Zapf AJ, Hardick J, McBryde B, Sauer LM, Fensterma. Impact of coinfection status and comorbidity on disease severity in adult emergency department patients with influenza B. Influenza Other Respir Viruses. 2021 Sep 17..  Abstract  
submitted by kickingbird at Sep, 22, 2021 from Influenza Other Respir Viruses. 2021 Sep 17. (via https://onlinelibrary.wiley.com/doi/10.1111/irv.12907)
Background: Influenza B accounts for approximately one fourth of the seasonal influenza burden. However, research on the importance of influenza B has received less attention compared to influenza A. We ...

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