Song Y, Huang H, Hu Y, Zhang J, Li F, Yin X, Shi J. A genome-wide CRISPR/Cas9 gene knockout screen identifies immunoglobulin superfamily DCC subclass member 4 as a key host factor that promotes influenza virus endocytosis. PLoS Pathog. 2021 Dec 6;17(12):e1010141. Abstract
submitted by kickingbird at Dec, 8, 2021 from PLoS Pathog. 2021 Dec 6;17(12):e1010141 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Influenza virus infection is dependent on host cellular factors, and identification of these factors and their underlying mechanisms can provide important information for the development of strategies ... Kong H, Fan S, Takada K, Imai M, Neumann G, Kawaok. H3N2 Influenza Viruses with 12- or 16-Amino Acid Deletions in the Receptor-Binding Region of Their Hemagglutinin Protein. mBio. 2021 Dec 7:e0151221. Abstract
submitted by kickingbird at Dec, 8, 2021 from mBio. 2021 Dec 7:e0151221 (via https://journals.asm.org/doi/10.1128/mBio.01512-21)
Human influenza viruses evade host immune responses by accumulating mutations around the receptor-binding region of the hemagglutinin (HA) protein, which is composed of three key elements, the 130-loop, ... Tani N, Kawai N, Chong Y, Bando T, Iwaki N, Kashiw. Susceptibility of epidemic viruses to neuraminidase inhibitors and treatment-emergent resistance in the Japanese 2019-20 influenza season. J Infect. 2021 Nov 30:S0163-4453(21)00583-1. Abstract
submitted by kickingbird at Dec, 6, 2021 from J Infect. 2021 Nov 30:S0163-4453(21)00583-1 (via https://www.journalofinfection.com/article/S0163-4453(21)005)
Objectives: To investigate the susceptibility of epidemic influenza viruses to neuraminidase inhibitors (NAIs) and the emergence of resistant viruses after treatment, a prospective, observational study ... Si YJ, Park YR, Baek YG, Park MJ, Lee EK, Lee KN,. Pathogenesis and genetic characteristics of low pathogenic avian influenza H10 viruses isolated from migratory birds in South Korea during 2010-2019. Transbound Emerg Dis. 2021 Dec 4. Abstract
submitted by kickingbird at Dec, 6, 2021 from Transbound Emerg Dis. 2021 Dec 4 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14409)
Human infection by avian-origin subtype H10 influenza viruses has raised concerns about the pandemic potential of these microbes. H10 subtype low pathogenic avian influenza viruses (LPAIVs) have been isolated ... Hu J, Peng P, Li J, Zhang Q, Li R, Wang X, Gu M, H. Single Dose of Bivalent H5 and H7 Influenza Virus-Like Particle Protects Chickens Against Highly Pathogenic H5N1 and H7N9 Avian Influenza Viruses. Front Vet Sci. 2021 Nov 11;8:774630. Abstract
submitted by kickingbird at Dec, 4, 2021 from Front Vet Sci. 2021 Nov 11;8:774630 (via https://www.frontiersin.org/articles/10.3389/fvets.2021.7746)
Both H5N1 and H7N9 subtype avian influenza viruses cause enormous economic losses and pose considerable threats to public health. Bivalent vaccines against both two subtypes are more effective in control ... Spencer S, Chung JR, Belongia EA, Sundaram M, Meec. Impact of diabetes status on immunogenicity of trivalent inactivated influenza vaccine in older adults. Influenza Other Respir Viruses. 2021 Dec 3. Abstract
submitted by kickingbird at Dec, 4, 2021 from Influenza Other Respir Viruses. 2021 Dec 3 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.12933)
Individuals with type 2 diabetes mellitus experience high rates of influenza virus infection and complications. We compared the magnitude and duration of serologic response to trivalent influenza vaccine ... Kuroda Y, Okada A, Shimoda H, Miwa Y, Watamori A,. Influenza A virus infection in domestic ferrets. Jpn J Infect Dis. 2021 Nov 30. Abstract
submitted by kickingbird at Dec, 3, 2021 from Jpn J Infect Dis. 2021 Nov 30 (via https://www.jstage.jst.go.jp/article/yoken/advpub/0/advpub_J)
Ferrets are animals that are known to be susceptible to influenza A virus (IAV) infection. To evaluate the risk of IAV transmission from diseased ferrets to humans, we performed a serosurvey to detect ... Luo S, Xie Z, Li M, Li D, Xie L, Huang J, Zhang M,. Survey of low pathogenic avian influenza viruses in live poultry markets in Guangxi Province, Southern China, 2016-2019. Sci Rep. 2021 Dec 1;11(1):23223. Abstract
submitted by kickingbird at Dec, 3, 2021 from Sci Rep. 2021 Dec 1;11(1):23223 (via https://www.nature.com/articles/s41598-021-02639-8)
Low pathogenic avian influenza viruses (LPAIVs) have been widespread in poultry and wild birds throughout the world for many decades. LPAIV infections are usually asymptomatic or cause subclinical symptoms. ... Wu XX, Tang SJ, Yao SH, Zhou YQ, Xiao LL, Cheng LF. The viral distribution and pathological characteristics of BALB/c mice infected with highly pathogenic Influenza H7N9 virus. Virol J. 2021 Nov 29;18(1):237. Abstract
submitted by kickingbird at Dec, 2, 2021 from Virol J. 2021 Nov 29;18(1):237 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: The highly pathogenic Influenza H7N9 virus is believed to cause multiple organ infections. However, there have been few systematic animal experiments demonstrating the virus distribution after ... Zheng J, Chen F, Wu K, Wang J, Li F, Huang S, Lu J. Clinical and virological impact of single and dual infections with influenza A (H1N1) and SARS-CoV-2 in adult inpatients. PLoS Negl Trop Dis. 2021 Nov 29;15(11):e0009997. Abstract
submitted by kickingbird at Nov, 30, 2021 from PLoS Negl Trop Dis. 2021 Nov 29;15(11):e0009997 (via https://journals.plos.org/plosntds/article?id=10.1371/journa)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mimics the influenza A (H1N1) virus in terms of clinical presentation, transmission mechanism, and seasonal coincidence. Comprehensive data ... Xu L, Zhao L, Che J, Zhang Q, Cao R, Li X. Identification of novel influenza polymerase PB2 inhibitors using virtual screening approach and molecular dynamics simulation analysis of active compounds. Bioorg Med Chem. 2021 Nov 11;52:116515. Abstract
submitted by kickingbird at Nov, 30, 2021 from Bioorg Med Chem. 2021 Nov 11;52:116515 (via https://www.sciencedirect.com/science/article/abs/pii/S09680)
Hierarchical virtual screening combined with ADME prediction and cluster analysis methods were used to identify influenza virus PB2 inhibitors with high activity, good druggability properties, and diverse ... Zhou B, Wang L, Liang Y, Li J, Pan X. Arctiin suppresses H9N2 avian influenza virus-mediated inflammation via activation of Nrf2/HO-1 signaling. BMC Complement Med Ther. 2021 Nov 26;21(1):289. Abstract
submitted by kickingbird at Nov, 30, 2021 from BMC Complement Med Ther. 2021 Nov 26;21(1):289 (via https://bmccomplementmedtherapies.biomedcentral.com/articles)
Background: H9N2 avian influenza viruses (AIVs) infect avian and mammalian hosts and provide internal genes for new emerging highly pathogenic avian viruses that cause severe pneumonia with high mortality, ... Yin Y, Wang J, Xu X, Zhou B, Chen S, Qin T, Peng D. Riboflavin as a Mucosal Adjuvant for Nasal Influenza Vaccine. Vaccines (Basel). 2021 Nov 9;9(11):1296. Abstract
submitted by kickingbird at Nov, 30, 2021 from Vaccines (Basel). 2021 Nov 9;9(11):1296 (via https://www.mdpi.com/2076-393X/9/11/1296)
Intranasal immunization with whole inactivated virus (WIV) is an important strategy used for influenza prevention and control. However, a powerful mucosal adjuvant is required to improve nasal vaccine ... Lamotte LA, Tafforeau L. How Influenza A Virus NS1 Deals with the Ubiquitin System to Evade Innate Immunity. Viruses. 2021 Nov 19;13(11):2309. Abstract
submitted by kickingbird at Nov, 30, 2021 from Viruses. 2021 Nov 19;13(11):2309 (via https://www.mdpi.com/1999-4915/13/11/2309)
Ubiquitination is a post-translational modification regulating critical cellular processes such as protein degradation, trafficking and signaling pathways, including activation of the innate immune response. ... Li Y, Zhang X, Liu Y, Feng Y, Wang T, Ge Y, Kong Y. Characterization of Canine Influenza Virus A (H3N2) Circulating in Dogs in China from 2016 to 2018. Viruses. 2021 Nov 15;13(11):2279.. Abstract
submitted by kickingbird at Nov, 30, 2021 from Viruses. 2021 Nov 15;13(11):2279. (via https://www.mdpi.com/1999-4915/13/11/2279)
Avian H3N2 influenza virus follows cross-host transmission and has spread among dogs in Asia since 2005. After 2015-2016, a new H3N2 subtype canine influenza epidemic occurred in dogs in North America ... Yeo JY, Gan SK. Peering into Avian Influenza A(H5N8) for a Framework towards Pandemic Preparedness. Viruses. 2021 Nov 15;13(11):2276. Abstract
submitted by kickingbird at Nov, 30, 2021 from Viruses. 2021 Nov 15;13(11):2276 (via https://www.mdpi.com/1999-4915/13/11/2276)
2014 marked the first emergence of avian influenza A(H5N8) in Jeonbuk Province, South Korea, which then quickly spread worldwide. In the midst of the 2020-2021 H5N8 outbreak, it spread to domestic poultry ... Lee YN, Lee DH, Kwon JH, Shin JI, Hong SY, Cha RM,. Genetic Characterization of Novel H7Nx Low Pathogenic Avian Influenza Viruses from Wild Birds in South Korea during the Winter of 2020-2021. Viruses. 2021 Nov 13;13(11):2274. Abstract
submitted by kickingbird at Nov, 30, 2021 from Viruses. 2021 Nov 13;13(11):2274 (via https://www.mdpi.com/1999-4915/13/11/2274)
Zoonotic infection with avian influenza viruses (AIVs) of subtype H7, such as H7N9 and H7N4, has raised concerns worldwide. During the winter of 2020-2021, five novel H7 low pathogenic AIVs (LPAIVs) containing ... Duong BT, Bal J, Sung HW, Yeo SJ, Park H. Molecular Analysis of the Avian H7 Influenza Viruses Circulating in South Korea during 2018-2019: Evolutionary Significance and Associated Zoonotic Threats. Viruses. 2021 Nov 11;13(11):2260. Abstract
submitted by kickingbird at Nov, 30, 2021 from Viruses. 2021 Nov 11;13(11):2260 (via https://www.mdpi.com/1999-4915/13/11/2260)
Avian influenza virus (AIV) subtypes H5 and H7, possessing the ability to mutate spontaneously from low pathogenic (LP) to highly pathogenic (HP) variants, are major concerns for enormous socio-economic ... Ren Y, Long S, Cao S. Molecular Docking and Virtual Screening of an Influenza Virus Inhibitor That Disrupts Protein-Protein Interactions. Viruses. 2021 Nov 5;13(11):2229. Abstract
submitted by kickingbird at Nov, 30, 2021 from Viruses. 2021 Nov 5;13(11):2229 (via https://www.mdpi.com/1999-4915/13/11/2229)
Influenza is an acute respiratory infection caused by the influenza virus, but few drugs are available for its treatment. Consequently, researchers have been engaged in efforts to discover new antiviral ... Ye Q, Phan T, Hu WS, Liu X, Fan L, Tan WS, Zhao L. Transcriptomic Characterization Reveals Attributes of High Influenza Virus Productivity in MDCK Cells. Viruses. 2021 Nov 1;13(11):2200. Abstract
submitted by kickingbird at Nov, 30, 2021 from Viruses. 2021 Nov 1;13(11):2200 (via https://www.mdpi.com/1999-4915/13/11/2200)
The Madin-Darby Canine Kidney (MDCK) cell line is among the most commonly used cell lines for the production of influenza virus vaccines. As cell culture-based manufacturing is poised to replace egg-based ... 7775 items, 20/Page, Page[80/389][|<<] [|<] [71] [72] [73] [74] [75] [76] [77] [78] [79] [80] [>|] [>>|] |
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